Nodal and ALK7 inhibit proliferation and induce apoptosis in human trophoblast cells

Journal of Biological Chemistry

Volumn 279, Issue 30, 2004, Pages 31277-31286

  Munir, Sadia ^a   Xu, Guoxiong ^a   Wu, Yaojiong ^b   Yang, Burton ^b   Lala, Peeyush K ^c   Peng, Chun ^a  

^a YORK UNIVERSITY   (Canada)

^b SUNNYBROOK RESEARCH INSTITUTE   (Canada)

^c UNIVERSITY OF WESTERN ONTARIO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

BIOASSAY; CELLS; GROWTH KINETICS; METABOLISM; RNA; TISSUE;

CELL CYCLE; CELL PROLIFERATION; FLOW CYTOMETRY; HUMAN TROPHOBLAST CELLS;

ENZYME INHIBITION;

ACTIVIN RECEPTOR LIKE KINASE 7; BISBENZIMIDE; CASPASE 3; CYCLIN D1; CYCLIN DEPENDENT KINASE 2; CYCLIN E; MESSENGER RNA; PROTEIN NODAL; PROTEIN P27; RECEPTOR; SMAD2 PROTEIN; SMAD3 PROTEIN; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CELL COUNT; CELL CYCLE G1 PHASE; CELL METABOLISM; CELL PROLIFERATION; CHORIOCARCINOMA; CONTROLLED STUDY; FLOW CYTOMETRY; GENE OVEREXPRESSION; GROWTH INHIBITION; HUMAN; HUMAN CELL; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN FAMILY; SIGNAL TRANSDUCTION; STAINING; TROPHOBLAST; WESTERN BLOTTING;

ACTIVIN RECEPTORS, TYPE I; APOPTOSIS; BASE SEQUENCE; CELL DIVISION; CELL LINE; DNA PRIMERS; DNA-BINDING PROTEINS; FEMALE; G1 PHASE; GENE EXPRESSION; HUMANS; PREGNANCY; RNA, MESSENGER; SIGNAL TRANSDUCTION; SMAD2 PROTEIN; SMAD3 PROTEIN; TRANS-ACTIVATORS; TRANSFECTION; TRANSFORMING GROWTH FACTOR BETA; TROPHOBLASTS;

VERTEBRATA;

EID: 3843110160     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M400641200     Document Type: Article

References (48)

1. Massagué, J., and Chen, Y.-G. (2000) Genes Dev. 6, 627-644
2. Zimmerman, C. M., and Padgett, R. W. (2000) Gene (Amst.) 249, 17-30
3. Chang, H., Brown, C. W., and Matzuk, M. M. (2002) Endocr. Rev. 23, 787-823
4. Graham, C. H., and Lala, P. K. (1991) J. Cell. Physiol. 148, 228-234
5. Graham, C. H., Lysiak, J. J., McCrae, K. R., and Lala, P. K. (1992) Biol. Reprod. 46, 561-572
6. Peng, C. (2003) J. Obstet. Gynaecol. Can. 25, 834-845
7. Brennan, J., Norris, D. P., and Robertson, E. J. (2002) Genes Dev. 16, 2339-2344
8. Eimon, P. M., and Harland, R. M. (2002) Development (Camb.) 129, 3089-3103
9. Nonaka, S., Shiratori, H., Saijoh, Y., and Hamada, H. (2002) Nature 418, 96-99
10. Iannaccone, P. M., Chou, X., Khokha, M., Boucher, D., and Kuehn, M. R. (1992) Dev. Dyn. 194, 198-208
11. Ma, G. T., Soloveva, V., Tzeng, S.-J., Lowe, L. A., Pfendler, K. C., Iannacone, P. M., Kuehn, M. R., and Linzer, D. H. (2001) Dev. Biol. 236, 124-131
12. Roberts, H. J., Hu, S., Qiu, Q., Leung, P. C. K., Cannigia, I., Gruslin, A., Tsang, B., and Peng, C. (2003) Biol. Reprod. 68, 1719-1726
13. Wrana, J. L., Attisano, L., Wieser, R., Ventura, F., and Massagué, J. (1994) Nature 370, 341-347
14. Miyazawa, K., Shinozaki, M., Hara, T., Furuya, T., and Miyazono, K. (2002) Genes Cells 7, 1191-1204
15. Liu, F. (2003) Front. Biosci. 8, S1280-S1303
16. Derynck, R., and Zhang, Y. E. (2003) Nature 425, 577-584
17. Tsuchida, K., Sawchenko, P. E., Nishikawa, S. I., and Vale, W. W. (1996) Mol. Cell. Neurosci. 7, 467-478
18. Rydén, M., Imamura, T., Jörnvall, H., Belluardo, N., Neveu, I., Trupp, M., Okadome, T., ten Dijke, P., and Ibanez, C. F. (1996) J. Biol. Chem. 271, 30603-30609
19. Reissmann, E., Jornvall, H., Blokzijl, A., Anderson, O., Chang, C., Minchiotti, G., Persico, M. G., Ibanex, C., and Brivanlou, A. H. (2001) Genes Dev. 15, 2010-2022
20. Bondestam, J., Huotari, M. A., Moren, A., Ustinov, J., Kaivo-Oja, N., Kallio, J., Horelli-Kuitunen, N., Aaltonen, J., Fujii, M., Moustakas, A., ten Dijke, P., Otonkoski, T., and Ritvos, O. (2001) Cytogenet. Cell Genet. 95, 157-162
21. Jörnvall, H., Blokzijl, A., ten Dijke, P., and Ibanez, C. F. (2001) J. Biol. Chem. 276, 5140-5146
22. Watanabe, R., Yamada, Y., Ihara, Y., Someya, Y., Kubota, A., Kagimoto, S., Kuroe, A., Iwakura, T., Shen, Z. P., Inada, A., Adachi, T., Ban, N., Miyawaki, K., Sunaga, Y., Tsuda, K., and Seino, Y. (1999) Biochem. Biophys. Res. Commun. 254, 707-712
23. Yeo, C., and Whitman, M. (2001) Mol. Cell 7, 949-957
24. Yan, Y. T., Liu, J. J., Luo, Y., Chaosu, E., Haltiwanger, R. S., Abate-Shen, C., and Shen, M. M. (2002) Mol. Cell. Biol. 22, 4439-4449
25. Kumar, A., Novoselov, V., Celeste, A. J., Wolfman, N. M., ten Dijke, P., and Kuehn, M. R. (2001) J. Biol. Chem. 276, 656-661
26. Schafer, K. A. (1998) Vet. Pathol. 35, 461-478
27. Vidal, A., and Koff, A. (2000) Gene (Amst.) 247, 1-15
28. Morgan, D. O. (1997) Ann. Rev. Cell Dev. Biol. 13, 261-291
29. Donovan, J., and Slingerland, J. (2000) Breast Cancer Res. 2, 116-124
30. Graham, C. H., Hawley, T. S., Hawley, R. G., MacDougall, J. R., Kerbel, R. S., Khoo, N., and Lala, P. K. (1993) Exp. Cell Res. 206, 204-211
31. Xu, G., Chakraborty, C., and Lala, P. K. (2002) Biochem. Biophys. Res. Commun. 294, 1079-1086
32. Xu, G., Chakraborty, C., and Lala, P. K. (2001) Biochem. Biophys. Res. Commun. 287, 47-55
33. Wu, D., Luo, S., Wang, Y., Zhuang, L., Chen, Y., and Peng, C. (2001) Mol. Cell. Endocrinol. 175, 111-121
34. Bianco, C., Adkins, H. B., Wechselberger, C., Seno, M., Normanno, N., De Luca, A., Sun, Y., Khan, N., Kenney, N., Ebert, A., Williams, K. P., Sanicola, M., and Salomon, D. S. (2002) Mol. Cell. Biol. 22, 2586-2597
35. Adkins, H. B., Bianco, C., Schiffer, S. G., Rayhorn, P., Zafari, M., Cheung, A. E., Orozco, O., Olson, D., De Luca, A., Chen, L. L., Miatkowski, K., Benjamin, C., Normanno, N., Williams, K. P., Jarpe, M., LePage, D., Salomon, D., and Sanicola, M. (2003) J. Clin. Investig. 112, 575-587
36. Kim, B.-C., Van Gelder, H., Kim, T. A., Lee, H.-J., Baik, K. G., Chun, H. H., Lee, D. A., Choi, K. S., and Kim, S.-J. (2004) J. Biol. Chem. 279, 28458-28465
37. Grana, X., and Reddy, E. P. (1995) Oncogene 11, 211-219
38. Ohtsubo, M., Theodoras, A. M., Schumacher, J., Roberts, J. M., and Pagano, M. (1995) Mol. Cell. Biol. 15, 2612-2624
39. Krude, T., Jackman, M., Pines, J., and Laskey, R. A. (1997) Cell 88, 109-119
40. Sherr, C. J., and Roberts, J. M. (1995) Genes Dev. 9, 1149-1163
41. Philipp-Staheli, J., Payne, S. R., and Kemp, C. J. (2001) Exp. Cell Res. 264, 148-168
42. Akhurst, R. J., and Derynck, R. (2001) Trends Cell Biol. 11, S44-S51
43. Wieser, R. (2001) Curr. Opin. Oncol. 13, 70-77
44. Reiss, M. (1999) Microbes Infect. 1, 1327-1347
45. Graham, C. H., Connelly, I., MacDougall, J. R., Kerbel, R. S., Stetler-Stevenson, W. G., and Lala, P. K. (1994) Exp. Cell Res. 214, 93-99
46. Aboagye-Mathiesen, G., Zdravkovic, M., Toth, F. D., Graham, C. H., Lala, P. K., and Ebbesen, P. (1996) Early Pregnancy 2, 102-112
47. Luo, S., Yu, H., Wu, D., and Peng, C. (2002) Mol. Hum. Reprod. 8, 318-325
48. Xu, G., Chakraborty, C., and Lala, P. K. (2003) Biochem. Biophys. Res. Commun. 300, 383-390