SCOPUS 정보 검색 플랫폼

Volumn 200, Issue 4, 2013, Pages 537-549

Canonical Wnt signaling inhibits osteoclastogenesis independent of osteoprotegerin

(8) Albers, Joachim a Keller, Johannes a Baranowsky, Anke a Beil, Frank Timo a Catala Lehnen, Philip a Schulze, Jochen a Amling, Michael a Schinke, Thorsten a

a UNIVERSITY MEDICAL CENTER HAMBURG EPPENDORF (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

BETA CATENIN; OSTEOPROTEGERIN; WNT3A PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL DIFFERENTIATION; CONTROLLED STUDY; MOUSE; NONHUMAN; OSSIFICATION; OSTEOBLAST; OSTEOCLAST; OSTEOCLASTOGENESIS; OSTEOLYSIS; OSTEOPENIA; PRIORITY JOURNAL; WNT SIGNALING PATHWAY;

ANIMALS; BETA CATENIN; BONE RESORPTION; CELL DIFFERENTIATION; GENE EXPRESSION PROFILING; MICE; MICE, INBRED C57BL; OSTEOCLASTS; OSTEOGENESIS; OSTEOPROTEGERIN; RECEPTORS, G-PROTEIN-COUPLED; RECEPTORS, WNT; WNT SIGNALING PATHWAY; WNT3A PROTEIN;

EID: 84874387975 PISSN: 00219525 EISSN: 15408140 Source Type: Journal
DOI: 10.1083/jcb.201207142 Document Type: Article

Times cited : (157)

References (38)

1
- 79955482044
- Control of bone formation by the serpentine receptor Frizzled-9
- Albers, J., J. Schulze, F.T. Beil, M. Gebauer, A. Baranowsky, J. Keller, R.P. Marshall, K. Wintges, F.W. Friedrich, M. Priemel, et al. 2011. Control of bone formation by the serpentine receptor Frizzled-9. J. Cell Biol. 192:1057-1072. http://dx.doi.org/10.1083/jcb.201008012
- (2011) J. Cell Biol. , vol.192 , pp. 1057-1072
- Albers, J.¹ Schulze, J.² Beil, F.T.³ Gebauer, M.⁴ Baranowsky, A.⁵ Keller, J.⁶ Marshall, R.P.⁷ Wintges, K.⁸ Friedrich, F.W.⁹ Priemel, M.¹⁰

2
- 33751032130
- Wnt signaling: a key regulator of bone mass
- Baron, R., G. Rawadi, and S. Roman-Roman. 2006. Wnt signaling: a key regulator of bone mass. Curr. Top. Dev. Biol. 76:103-127. http://dx.doi.org/10.1016/S0070-2153(06)76004-5
- (2006) Curr. Top. Dev. Biol. , vol.76 , pp. 103-127
- Baron, R.¹ Rawadi, G.² Roman-Roman, S.³

3
- 0037118285
- High bone density due to a mutation in LDL-receptor-related protein 5
- Boyden, L.M., J. Mao, J. Belsky, L. Mitzner, A. Farhi, M.A. Mitnick, D. Wu, K. Insogna, and R.P. Lifton. 2002. High bone density due to a mutation in LDL-receptor-related protein 5. N. Engl. J. Med. 346:1513-1521. http://dx.doi.org/10.1056/NEJMoa013444
- (2002) N. Engl. J. Med. , vol.346 , pp. 1513-1521
- Boyden, L.M.¹ Mao, J.² Belsky, J.³ Mitzner, L.⁴ Farhi, A.⁵ Mitnick, M.A.⁶ Wu, D.⁷ Insogna, K.⁸ Lifton, R.P.⁹

4
- 0037673945
- Osteoclast differentiation and activation
- Boyle, W.J., W.S. Simonet, and D.L. Lacey. 2003. Osteoclast differentiation and activation. Nature. 423:337-342. http://dx.doi.org/10.1038/nature01658
- (2003) Nature. , vol.423 , pp. 337-342
- Boyle, W.J.¹ Simonet, W.S.² Lacey, D.L.³

5
- 0035034603
- Inactivation of the betacatenin gene by Wnt1-Cre-mediated deletion results in dramatic brain malformation and failure of craniofacial development
- Brault, V., R. Moore, S. Kutsch, M. Ishibashi, D.H. Rowitch, A.P. McMahon, L. Sommer, O. Boussadia, and R. Kemler. 2001. Inactivation of the betacatenin gene by Wnt1-Cre-mediated deletion results in dramatic brain malformation and failure of craniofacial development. Development. 128:1253-1264.
- (2001) Development. , vol.128 , pp. 1253-1264
- Brault, V.¹ Moore, R.² Kutsch, S.³ Ishibashi, M.⁴ Rowitch, D.H.⁵ McMahon, A.P.⁶ Sommer, L.⁷ Boussadia, O.⁸ Kemler, R.⁹

6
- 0032079445
- osteoprotegerindeficient mice develop early onset osteoporosis and arterial calcification
- Bucay, N., I. Sarosi, C.R. Dunstan, S. Morony, J. Tarpley, C. Capparelli, S. Scully, H.L. Tan, W. Xu, D.L. Lacey, et al. 1998. osteoprotegerindeficient mice develop early onset osteoporosis and arterial calcification. Genes Dev. 12:1260-1268. http://dx.doi.org/10.1101/gad.12.9.1260
- (1998) Genes Dev. , vol.12 , pp. 1260-1268
- Bucay, N.¹ Sarosi, I.² Dunstan, C.R.³ Morony, S.⁴ Tarpley, J.⁵ Capparelli, C.⁶ Scully, S.⁷ Tan, H.L.⁸ Xu, W.⁹ Lacey, D.L.¹⁰

7
- 0033177995
- Conditional gene targeting in macrophages and granulocytes using LysMcre mice
- Clausen, B.E., C. Burkhardt, W. Reith, R. Renkawitz, and I. Förster. 1999. Conditional gene targeting in macrophages and granulocytes using LysMcre mice. Transgenic Res. 8:265-277. http://dx.doi.org/10.1023/A:1008942828960
- (1999) Transgenic Res. , vol.8 , pp. 265-277
- Clausen, B.E.¹ Burkhardt, C.² Reith, W.³ Renkawitz, R.⁴ Förster, I.⁵

8
- 84861986053
- Wnt/β-catenin signaling and disease
- Clevers, H., and R. Nusse. 2012. Wnt/β-catenin signaling and disease. Cell. 149:1192-1205. http://dx.doi.org/10.1016/j.cell.2012.05.012
- (2012) Cell. , vol.149 , pp. 1192-1205
- Clevers, H.¹ Nusse, R.²

9
- 79958171733
- Lrp5 functions in bone to regulate bone mass
- Cui, Y., P.J. Niziolek, B.T. MacDonald, C.R. Zylstra, N. Alenina, D.R. Robinson, Z. Zhong, S. Matthes, C.M. Jacobsen, R.A. Conlon, et al. 2011. Lrp5 functions in bone to regulate bone mass. Nat. Med. 17:684-691. http://dx.doi.org/10.1038/nm.2388
- (2011) Nat. Med. , vol.17 , pp. 684-691
- Cui, Y.¹ Niziolek, P.J.² MacDonald, B.T.³ Zylstra, C.R.⁴ Alenina, N.⁵ Robinson, D.R.⁶ Zhong, Z.⁷ Matthes, S.⁸ Jacobsen, C.M.⁹ Conlon, R.A.¹⁰

10
- 0035811492
- Insights into Wnt binding and signalling from the structures of two Frizzled cysteine-rich domains
- Dann, C.E., J.C. Hsieh, A. Rattner, D. Sharma, J. Nathans, and D.J. Leahy. 2001. Insights into Wnt binding and signalling from the structures of two Frizzled cysteine-rich domains. Nature. 412:86-90. http://dx.doi.org/10.1038/35083601
- (2001) Nature. , vol.412 , pp. 86-90
- Dann, C.E.¹ Hsieh, J.C.² Rattner, A.³ Sharma, D.⁴ Nathans, J.⁵ Leahy, D.J.⁶

11
- 17844372752
- Wnt/beta-catenin signaling in mesenchymal progenitors controls osteoblast and chondrocyte differentiation during vertebrate skeletogenesis
- Day, T.F., X. Guo, L. Garrett-Beal, and Y. Yang. 2005. Wnt/beta-catenin signaling in mesenchymal progenitors controls osteoblast and chondrocyte differentiation during vertebrate skeletogenesis. Dev. Cell. 8:739-750. http://dx.doi.org/10.1016/j.devcel.2005.03.016
- (2005) Dev. Cell. , vol.8 , pp. 739-750
- Day, T.F.¹ Guo, X.² Garrett-Beal, L.³ Yang, Y.⁴

12
- 34347254641
- The soluble wnt receptor Frizzled8CRD-hFc inhibits the growth of teratocarcinomas in vivo
- DeAlmeida, V.I., L. Miao, J.A. Ernst, H. Koeppen, P. Polakis, and B. Rubinfeld. 2007. The soluble wnt receptor Frizzled8CRD-hFc inhibits the growth of teratocarcinomas in vivo. Cancer Res. 67:5371-5379. http://dx.doi.org/10.1158/0008-5472.CAN-07-0266
- (2007) Cancer Res. , vol.67 , pp. 5371-5379
- DeAlmeida, V.I.¹ Miao, L.² Ernst, J.A.³ Koeppen, H.⁴ Polakis, P.⁵ Rubinfeld, B.⁶

13
- 20244373613
- Canonical Wnt signaling in differentiated osteoblasts controls osteoclast differentiation
- Glass, D.A. II, P. Bialek, J.D. Ahn, M. Starbuck, M.S. Patel, H. Clevers, M.M. Taketo, F. Long, A.P. McMahon, R.A. Lang, and G. Karsenty. 2005. Canonical Wnt signaling in differentiated osteoblasts controls osteoclast differentiation. Dev. Cell. 8:751-764. http://dx.doi.org/10.1016/j.devcel.2005.02.017
- (2005) Dev. Cell. , vol.8 , pp. 751-764
- Glass, D.A.¹ Bialek, P.² Ahn, J.D.³ Starbuck, M.⁴ Patel, M.S.⁵ Clevers, H.⁶ Taketo, M.M.⁷ Long, F.⁸ McMahon, A.P.⁹ Lang, R.A.¹⁰ Karsenty, G.¹¹

14
- 18044386744
- LDL receptor-related protein 5 (LRP5) affects bone accrual and eye development
- Osteoporosis-Pseudoglioma Syndrome Collaborative Group
- Gong, Y., R.B. Slee, N. Fukai, G. Rawadi, S. Roman-Roman, A.M. Reginato, H. Wang, T. Cundy, F.H. Glorieux, D. Lev, et al; Osteoporosis-Pseudoglioma Syndrome Collaborative Group. 2001. LDL receptor-related protein 5 (LRP5) affects bone accrual and eye development. Cell. 197:513-523. http://dx.doi.org/10.1016/S0092-8674(01)00571-2
- (2001) Cell. , vol.107 , pp. 513-523
- Gong, Y.¹ Slee, R.B.² Fukai, N.³ Rawadi, G.⁴ Roman-Roman, S.⁵ Reginato, A.M.⁶ Wang, H.⁷ Cundy, T.⁸ Glorieux, F.H.⁹ Lev, D.¹⁰

15
- 0037673933
- Control of osteoblast function and regulation of bone mass
- Harada, S., and G.A. Rodan. 2003. Control of osteoblast function and regulation of bone mass. Nature. 423:349-355. http://dx.doi.org/10.1038/nature01660
- (2003) Nature. , vol.423 , pp. 349-355
- Harada, S.¹ Rodan, G.A.²

16
- 61849137831
- Inhibiting Dickkopf-1 (Dkk1) removes suppression of bone formation and prevents the development of osteolytic bone disease in multiple myeloma
- Heath, D.J., A.D. Chantry, C.H. Buckle, L. Coulton, J.D. Shaughnessy Jr., H.R. Evans, J.A. Snowden, D.R. Stover, K. Vanderkerken, and P.I. Croucher. 2009. Inhibiting Dickkopf-1 (Dkk1) removes suppression of bone formation and prevents the development of osteolytic bone disease in multiple myeloma. J. Bone Miner. Res. 24:425-436. http://dx.doi.org/10.1359/jbmr.081104
- (2009) J. Bone Miner. Res. , vol.24 , pp. 425-436
- Heath, D.J.¹ Chantry, A.D.² Buckle, C.H.³ Coulton, L.⁴ Shaughnessy Jr., J.D.⁵ Evans, H.⁶ Snowden, J.A.⁷ Stover, D.R.⁸ Vanderkerken, K.⁹ Croucher, P.I.¹⁰

17
- 17844363974
- Canonical Wnt/beta-catenin signaling prevents osteoblasts from differentiating into chondrocytes
- Hill, T.P., D. Später, M.M. Taketo, W. Birchmeier, and C. Hartmann. 2005. Canonical Wnt/beta-catenin signaling prevents osteoblasts from differentiating into chondrocytes. Dev. Cell. 8:727-738. http://dx.doi.org/10.1016/j.devcel.2005.02.013
- (2005) Dev. Cell. , vol.8 , pp. 727-738
- Hill, T.P.¹ Später, D.² Taketo, M.M.³ Birchmeier, W.⁴ Hartmann, C.⁵

18
- 20444376156
- Essential role of beta-catenin in postnatal bone acquisition
- Holmen, S.L., C.R. Zylstra, A. Mukherjee, R.E. Sigler, M.C. Faugere, M.L. Bouxsein, L. Deng, T.L. Clemens, and B.O. Williams. 2005. Essential role of beta-catenin in postnatal bone acquisition. J. Biol. Chem. 280:21162-21168. http://dx.doi.org/10.1074/jbc.M501900200
- (2005) J. Biol. Chem. , vol.280 , pp. 21162-21168
- Holmen, S.L.¹ Zylstra, C.R.² Mukherjee, A.³ Sigler, R.E.⁴ Faugere, M.C.⁵ Bouxsein, M.L.⁶ Deng, L.⁷ Clemens, T.L.⁸ Williams, B.O.⁹

19
- 0037092049
- Cbfa1- independent decrease in osteoblast proliferation, osteopenia, and persistent embryonic eye vascularization in mice deficient in Lrp5, a Wnt coreceptor
- Kato, M., M.S. Patel, R. Levasseur, I. Lobov, B.H. Chang, D.A. Glass II, C. Hartmann, L. Li, T.H. Hwang, C.F. Brayton, et al. 2002. Cbfa1- independent decrease in osteoblast proliferation, osteopenia, and persistent embryonic eye vascularization in mice deficient in Lrp5, a Wnt coreceptor. J. Cell Biol. 157:303-314. http://dx.doi.org/10.1083/jcb.200201089
- (2002) J. Cell Biol. , vol.157 , pp. 303-314
- Kato, M.¹ Patel, M.S.² Levasseur, R.³ Lobov, I.⁴ Chang, B.H.⁵ Glass, D.A.⁶ Hartmann, C.⁷ Li, L.⁸ Hwang, T.H.⁹ Brayton, C.F.¹⁰

20
- 77953407742
- Osteocyte Wnt/beta-catenin signaling is required for normal bone homeostasis
- Kramer, I., C. Halleux, H. Keller, M. Pegurri, J.H. Gooi, P.B. Weber, J.Q. Feng, L.F. Bonewald, and M. Kneissel. 2010. Osteocyte Wnt/beta-catenin signaling is required for normal bone homeostasis. Mol. Cell. Biol. 30:3071- 3085. http://dx.doi.org/10.1128/MCB.01428-09
- (2010) Mol. Cell. Biol. , vol.30 , pp. 3071-3085
- Kramer, I.¹ Halleux, C.² Keller, H.³ Pegurri, M.⁴ Gooi, J.H.⁵ Weber, P.B.⁶ Feng, J.Q.⁷ Bonewald, L.F.⁸ Kneissel, M.⁹

21
- 33748156090
- Dkk1-mediated inhibition of Wnt signaling in bone results in osteopenia
- Li, J., I. Sarosi, R.C. Cattley, J. Pretorius, F. Asuncion, M. Grisanti, S. Morony, S. Adamu, Z. Geng, W. Qiu, et al. 2006. Dkk1-mediated inhibition of Wnt signaling in bone results in osteopenia. Bone. 39:754-766. http://dx.doi.org/10.1016/j.bone.2006.03.017
- (2006) Bone. , vol.39 , pp. 754-766
- Li, J.¹ Sarosi, I.² Cattley, R.C.³ Pretorius, J.⁴ Asuncion, F.⁵ Grisanti, M.⁶ Morony, S.⁷ Adamu, S.⁸ Geng, Z.⁹ Qiu, W.¹⁰

22
- 0036138175
- A mutation in the LDL receptor-related protein 5 gene results in the autosomal dominant high-bone-mass trait
- Little, R.D., J.P. Carulli, R.G. Del Mastro, J. Dupuis, M. Osborne, C. Folz, S.P. Manning, P.M. Swain, S.C. Zhao, B. Eustace, et al. 2002. A mutation in the LDL receptor-related protein 5 gene results in the autosomal dominant high-bone-mass trait. Am. J. Hum. Genet. 70:11-19. http://dx.doi.org/10.1086/338450
- (2002) Am. J. Hum. Genet. , vol.70 , pp. 11-19
- Little, R.D.¹ Carulli, J.P.² Del Mastro, R.G.³ Dupuis, J.⁴ Osborne, M.⁵ Folz, C.⁶ Manning, S.P.⁷ Swain, P.M.⁸ Zhao, S.C.⁹ Eustace, B.¹⁰

23
- 84858007236
- Wnt5a-Ror2 signaling between osteoblast-lineage cells and osteoclast precursors enhances osteoclastogenesis
- Maeda, K., Y. Kobayashi, N. Udagawa, S. Uehara, A. Ishihara, T. Mizoguchi, Y. Kikuchi, I. Takada, S. Kato, S. Kani, et al. 2012. Wnt5a-Ror2 signaling between osteoblast-lineage cells and osteoclast precursors enhances osteoclastogenesis. Nat. Med. 18:405-412. http://dx.doi.org/10.1038/nm.2653
- (2012) Nat. Med. , vol.18 , pp. 405-412
- Maeda, K.¹ Kobayashi, Y.² Udagawa, N.³ Uehara, S.⁴ Ishihara, A.⁵ Mizoguchi, T.⁶ Kikuchi, Y.⁷ Takada, I.⁸ Kato, S.⁹ Kani, S.¹⁰

24
- 84863239847
- TREM2 and β-catenin regulate bone homeostasis by controlling the rate of osteoclastogenesis
- Otero, K., M. Shinohara, H. Zhao, M. Cella, S. Gilfillan, A. Colucci, R. Faccio, F.P. Ross, S.L. Teitelbaum, H. Takayanagi, and M. Colonna. 2012. TREM2 and β-catenin regulate bone homeostasis by controlling the rate of osteoclastogenesis. J. Immunol. 188:2612-2621. http://dx.doi.org/10.4049/jimmunol.1102836
- (2012) J. Immunol. , vol.188 , pp. 2612-2621
- Otero, K.¹ Shinohara, M.² Zhao, H.³ Cella, M.⁴ Gilfillan, S.⁵ Colucci, A.⁶ Faccio, R.⁷ Ross, F.P.⁸ Teitelbaum, S.L.⁹ Takayanagi, H.¹⁰ Colonna, M.¹¹

25
- 33751547539
- How many drug targets are there?
- Overington, J.P., B. Al-Lazikani, and A.L. Hopkins. 2006. How many drug targets are there? Nat. Rev. Drug Discov. 5:993-996. http://dx.doi.org/10.1038/nrd2199
- (2006) Nat. Rev. Drug Discov. , vol.5 , pp. 993-996
- Overington, J.P.¹ Al-Lazikani, B.² Hopkins, A.L.³

26
- 0023488581
- Bone histomorphometry: standardization of nomenclature, symbols, and units
- Report of the ASBMR Histomorphometry Nomenclature Committee
- Parfitt, A.M., M.K. Drezner, F.H. Glorieux, J.A. Kanis, H. Malluche, P.J. Meunier, S.M. Ott, and R.R. Recker; Report of the ASBMR Histomorphometry Nomenclature Committee. 1987. Bone histomorphometry: standardization of nomenclature, symbols, and units. J. Bone Miner. Res. 2:595-610. http://dx.doi.org/10.1002/jbmr.5650020617
- (1987) J. Bone Miner. Res. , vol.2 , pp. 595-610
- Parfitt, A.M.¹ Drezner, M.K.² Glorieux, F.H.³ Kanis, J.A.⁴ Malluche, H.⁵ Meunier, P.J.⁶ Ott, S.M.⁷ Recker, R.R.⁸

27
- 47649120741
- Wnt3a signaling within bone inhibits multiple myeloma bone disease and tumor growth
- Qiang, Y.W., J.D. Shaughnessy Jr., and S. Yaccoby. 2008. Wnt3a signaling within bone inhibits multiple myeloma bone disease and tumor growth. Blood. 112:374-382. http://dx.doi.org/10.1182/blood-2007-10-120253
- (2008) Blood. , vol.112 , pp. 374-382
- Qiang, Y.W.¹ Shaughnessy Jr., J.D.² Yaccoby, S.³

28
- 79953751008
- Osteoporosis: now and the future
- Rachner, T.D., S. Khosla, and L.C. Hofbauer. 2011. Osteoporosis: now and the future. Lancet. 377:1276-1287. http://dx.doi.org/10.1016/S0140-6736(10)62349-5
- (2011) Lancet. , vol.377 , pp. 1276-1287
- Rachner, T.D.¹ Khosla, S.² Hofbauer, L.C.³

29
- 84859796622
- Novel therapies in benign and malignant bone diseases
- Rachner, T.D., P. Hadji, and L.C. Hofbauer. 2012. Novel therapies in benign and malignant bone diseases. Pharmacol. Ther. 134:338-344. http://dx.doi.org/10.1016/j.pharmthera.2012.02.005
- (2012) Pharmacol. Ther. , vol.134 , pp. 338-344
- Rachner, T.D.¹ Hadji, P.² Hofbauer, L.C.³

30
- 34748812548
- The Frizzled family of unconventional G-protein- coupled receptors
- Schulte, G., and V. Bryja. 2007. The Frizzled family of unconventional G-protein- coupled receptors. Trends Pharmacol. Sci. 28:518-525. http://dx.doi.org/10.1016/j.tips.2007.09.001
- (2007) Trends Pharmacol. Sci. , vol.28 , pp. 518-525
- Schulte, G.¹ Bryja, V.²

31
- 77956546077
- Negative regulation of bone formation by the transmembrane Wnt antagonist Kremen-2
- Schulze, J., S. Seitz, H. Saito, M. Schneebauer, R.P. Marshall, A. Baranowsky, B. Busse, A.F. Schilling, F.W. Friedrich, J. Albers, et al. 2010. Negative regulation of bone formation by the transmembrane Wnt antagonist Kremen-2. PLoS ONE. 5:e10309. http://dx.doi.org/10.1371/journal.pone.0010309
- (2010) PLoS ONE. , vol.5
- Schulze, J.¹ Seitz, S.² Saito, H.³ Schneebauer, M.⁴ Marshall, R.P.⁵ Baranowsky, A.⁶ Busse, B.⁷ Schilling, A.F.⁸ Friedrich, F.W.⁹ Albers, J.¹⁰

32
- 79953065064
- Interleukin-33 is expressed in differentiated osteoblasts and blocks osteoclast formation from bone marrow precursor cells
- Schulze, J., T. Bickert, F.T. Beil, M.M. Zaiss, J. Albers, K. Wintges, T. Streichert, K. Klaetschke, J. Keller, T.N. Hissnauer, et al. 2011. Interleukin-33 is expressed in differentiated osteoblasts and blocks osteoclast formation from bone marrow precursor cells. J. Bone Miner. Res. 26:704-717. http://dx.doi.org/10.1002/jbmr.269
- (2011) J. Bone Miner. Res. , vol.26 , pp. 704-717
- Schulze, J.¹ Bickert, T.² Beil, F.T.³ Zaiss, M.M.⁴ Albers, J.⁵ Wintges, K.⁶ Streichert, T.⁷ Klaetschke, K.⁸ Keller, J.⁹ Hissnauer, T.N.¹⁰

33
- 0043267732
- Genetic regulation of osteoclast development and function
- Teitelbaum, S.L., and F.P. Ross. 2003. Genetic regulation of osteoclast development and function. Nat. Rev. Genet. 4:638-649. http://dx.doi.org/10.1038/nrg1122
- (2003) Nat. Rev. Genet. , vol.4 , pp. 638-649
- Teitelbaum, S.L.¹ Ross, F.P.²

34
- 0346363760
- The role of the Wnt-signaling antagonist DKK1 in the development of osteolytic lesions in multiple myeloma
- Tian, E., F. Zhan, R. Walker, E. Rasmussen, Y. Ma, B. Barlogie, and J.D. Shaughnessy Jr. 2003. The role of the Wnt-signaling antagonist DKK1 in the development of osteolytic lesions in multiple myeloma. N. Engl. J. Med. 349:2483-2494. http://dx.doi.org/10.1056/NEJMoa030847
- (2003) N. Engl. J. Med. , vol.349 , pp. 2483-2494
- Tian, E.¹ Zhan, F.² Walker, R.³ Rasmussen, E.⁴ Ma, Y.⁵ Barlogie, B.⁶ Shaughnessy Jr., J.D.⁷

35
- 83255192191
- Biphasic and dosage-dependent regulation of osteoclastogenesis by β-catenin
- Wei, W., D. Zeve, J.M. Suh, X. Wang, Y. Du, J.E. Zerwekh, P.C. Dechow, J.M. Graff, and Y. Wan. 2011. Biphasic and dosage-dependent regulation of osteoclastogenesis by β-catenin. Mol. Cell. Biol. 31:4706-4719. http://dx.doi.org/10.1128/MCB.05980-11
- (2011) Mol. Cell. Biol. , vol.31 , pp. 4706-4719
- Wei, W.¹ Zeve, D.² Suh, J.M.³ Wang, X.⁴ Du, Y.⁵ Zerwekh, J.E.⁶ Dechow, P.C.⁷ Graff, J.M.⁸ Wan, Y.⁹

36
- 0037082324
- Target validation of G-protein coupled receptors
- Wise, A., K. Gearing, and S. Rees. 2002. Target validation of G-protein coupled receptors. Drug Discov. Today. 7:235-246. http://dx.doi.org/10.1016/S1359-6446(01)02131-6
- (2002) Drug Discov. Today. , vol.7 , pp. 235-246
- Wise, A.¹ Gearing, K.² Rees, S.³

37
- 33847397091
- Antibody-based inhibition of DKK1 suppresses tumor-induced bone resorption and multiple myeloma growth in vivo
- Yaccoby, S., W. Ling, F. Zhan, R. Walker, B. Barlogie, and J.D. Shaughnessy Jr. 2007. Antibody-based inhibition of DKK1 suppresses tumor-induced bone resorption and multiple myeloma growth in vivo. Blood. 199:2106- 2111. http://dx.doi.org/10.1182/blood-2006-09-047712
- (2007) Blood. , vol.109 , pp. 2106-2111
- Yaccoby, S.¹ Ling, W.² Zhan, F.³ Walker, R.⁴ Barlogie, B.⁵ Shaughnessy Jr., J.D.⁶

38
- 56349162283
- Lrp5 controls bone formation by inhibiting serotonin synthesis in the duodenum
- Yadav, V.K., J.H. Ryu, N. Suda, K.F. Tanaka, J.A. Gingrich, G. Schütz, F.H. Glorieux, C.Y. Chiang, J.D. Zajac, K.L. Insogna, et al. 2008. Lrp5 controls bone formation by inhibiting serotonin synthesis in the duodenum. Cell. 135:825-837. http://dx.doi.org/10.1016/j.cell.2008.09.059
- (2008) Cell. , vol.135 , pp. 825-837
- Yadav, V.K.¹ Ryu, J.H.² Suda, N.³ Tanaka, K.F.⁴ Gingrich, J.A.⁵ Schütz, G.⁶ Glorieux, F.H.⁷ Chiang, C.Y.⁸ Zajac, J.D.⁹ Insogna, K.L.¹⁰

* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.