메뉴 건너뛰기




Volumn 9, Issue SUPPL.1, 2013, Pages 144-158

Mass spectrometry based environmental metabolomics: A primer and review

Author keywords

FT ICR; LC MS MS; Mechanism; Metabolic fingerprinting; Orbitrap; Stress

Indexed keywords

3 CARENE; ACRYLIC ACID; BETAINE DERIVATIVE; CHLORPHENOTANE; DEHYDROABIETIC ACID; DIMETHYL SULFIDE; ENDOSULFAN; FLUORANTHENE; HERBICIDE; POLYCYCLIC AROMATIC HYDROCARBON; PYRENE; TERPINOLENE; TRIMETHYLAMINE;

EID: 84874367641     PISSN: 15733882     EISSN: 15733890     Source Type: Journal    
DOI: 10.1007/s11306-012-0412-x     Document Type: Review
Times cited : (127)

References (111)
  • 1
    • 79951721889 scopus 로고    scopus 로고
    • Metabolomics in pesticide research and development: Review and future perspectives
    • Aliferis, K. A., & Chrysayi-Tokousbalides, M. (2011). Metabolomics in pesticide research and development: Review and future perspectives. Metabolomics, 7, 35-53.
    • (2011) Metabolomics , vol.7 , pp. 35-53
    • Aliferis, K.A.1    Chrysayi-Tokousbalides, M.2
  • 2
    • 79955910093 scopus 로고    scopus 로고
    • Evolution and metabolic significance of the urea cycle in photosynthetic diatoms
    • Allen, A. E., Dupont, C. L., Obornik, M., Horak, A., Nunes-Nesi, A., McCrow, J. P., et al. (2011). Evolution and metabolic significance of the urea cycle in photosynthetic diatoms. Nature, 473, 203-207.
    • (2011) Nature , vol.473 , pp. 203-207
    • Allen, A.E.1    Dupont, C.L.2    Obornik, M.3    Horak, A.4    Nunes-Nesi, A.5    McCrow, J.P.6
  • 3
    • 74449088783 scopus 로고    scopus 로고
    • Inter-laboratory reproducibility of fast gas chromatography-electron impact-time of flight mass spectrometry (GC-EI-TOF/MS) based plant metabolomics
    • Allwood, J. W., Erban, A., de Koning, S., Dunn, W. B., Luedemann, A., Lommen, A., et al. (2009). Inter-laboratory reproducibility of fast gas chromatography-electron impact-time of flight mass spectrometry (GC-EI-TOF/MS) based plant metabolomics. Metabolomics, 5, 479-496.
    • (2009) Metabolomics , vol.5 , pp. 479-496
    • Allwood, J.W.1    Erban, A.2    de Koning, S.3    Dunn, W.B.4    Luedemann, A.5    Lommen, A.6
  • 4
    • 0031868164 scopus 로고    scopus 로고
    • The use of lipid metabolic profiling to assess the biological impact of marine sewage pollution
    • Avery, E. L., Dunstan, R. H., & Nell, J. A. (1998). The use of lipid metabolic profiling to assess the biological impact of marine sewage pollution. Archives of Environmental Contamination and Toxicology, 35, 229-235.
    • (1998) Archives of Environmental Contamination and Toxicology , vol.35 , pp. 229-235
    • Avery, E.L.1    Dunstan, R.H.2    Nell, J.A.3
  • 5
    • 70349510684 scopus 로고    scopus 로고
    • Metabolic profiling reveals growth stage variability in diatom exudates
    • Barofsky, A., Vidoudez, C., & Pohnert, G. (2009). Metabolic profiling reveals growth stage variability in diatom exudates. Limnology and Oceanography: Methods, 7, 382-390.
    • (2009) Limnology and Oceanography: Methods , vol.7 , pp. 382-390
    • Barofsky, A.1    Vidoudez, C.2    Pohnert, G.3
  • 8
    • 14744300520 scopus 로고    scopus 로고
    • Metabolomics applications of FT-ICR mass spectrometry
    • Brown, S. C., Kruppa, G., & Dasseux, J. L. (2005). Metabolomics applications of FT-ICR mass spectrometry. Mass Spectrometry Reviews, 24, 223-231.
    • (2005) Mass Spectrometry Reviews , vol.24 , pp. 223-231
    • Brown, S.C.1    Kruppa, G.2    Dasseux, J.L.3
  • 10
    • 61849165638 scopus 로고    scopus 로고
    • Environmental metabolomics: A critical review and future perspectives
    • Bundy, J. G., Davey, M. P., & Viant, M. R. (2009). Environmental metabolomics: A critical review and future perspectives. Metabolomics, 5, 3-21.
    • (2009) Metabolomics , vol.5 , pp. 3-21
    • Bundy, J.G.1    Davey, M.P.2    Viant, M.R.3
  • 11
    • 79959997053 scopus 로고    scopus 로고
    • Multi-segment direct inject nano-ESI-LTQ-FT-ICR-MS/MS for protein identification
    • Chen, J., Canales, L., & Neal, R. E. (2011). Multi-segment direct inject nano-ESI-LTQ-FT-ICR-MS/MS for protein identification. Proteome Science, 9, 38.
    • (2011) Proteome Science , vol.9 , pp. 38
    • Chen, J.1    Canales, L.2    Neal, R.E.3
  • 14
    • 37349118022 scopus 로고    scopus 로고
    • Population-specific metabolic phenotypes of Arabidopsis lyrata ssp. petraea
    • Davey, M. P., Burrell, M. M., Woodward, F. I., & Quick, W. P. (2008). Population-specific metabolic phenotypes of Arabidopsis lyrata ssp. petraea. New Phytologist, 177, 380-388.
    • (2008) New Phytologist , vol.177 , pp. 380-388
    • Davey, M.P.1    Burrell, M.M.2    Woodward, F.I.3    Quick, W.P.4
  • 15
    • 61849121750 scopus 로고    scopus 로고
    • Intraspecific variation in cold-temperature metabolic phenotypes of Arabidopsis lyrata ssp. petraea
    • Davey, M. P., Woodward, F. I., & Quick, W. P. (2009). Intraspecific variation in cold-temperature metabolic phenotypes of Arabidopsis lyrata ssp. petraea. Metabolomics, 5, 138-149.
    • (2009) Metabolomics , vol.5 , pp. 138-149
    • Davey, M.P.1    Woodward, F.I.2    Quick, W.P.3
  • 17
    • 0028997403 scopus 로고
    • Commentary on effects of anthropogenic and natural organic-chemicals on development, swimming behavior, and reproduction of Daphnia, a key member of aquatic ecosystems
    • Dodson, S. I., & Hanazato, T. (1995). Commentary on effects of anthropogenic and natural organic-chemicals on development, swimming behavior, and reproduction of Daphnia, a key member of aquatic ecosystems. Environmental Health Perspectives, 103, 7-11.
    • (1995) Environmental Health Perspectives , vol.103 , pp. 7-11
    • Dodson, S.I.1    Hanazato, T.2
  • 18
    • 16244402990 scopus 로고    scopus 로고
    • Metabolomics: Current analytical platforms and methodologies
    • Dunn, W. B., & Ellis, D. I. (2005). Metabolomics: Current analytical platforms and methodologies. Trends in Analytical Chemistry, 24, 285-294.
    • (2005) Trends in Analytical Chemistry , vol.24 , pp. 285-294
    • Dunn, W.B.1    Ellis, D.I.2
  • 19
    • 78650315006 scopus 로고    scopus 로고
    • Systems level studies of mammalian metabolomes: The roles of mass spectrometry and nuclear magnetic resonance spectroscopy
    • Dunn, W. B., Broadhurst, D. I., Atherton, H. J., Goodacre, R., & Griffin, J. L. (2011). Systems level studies of mammalian metabolomes: The roles of mass spectrometry and nuclear magnetic resonance spectroscopy. Chemical Society Reviews, 40, 387-426.
    • (2011) Chemical Society Reviews , vol.40 , pp. 387-426
    • Dunn, W.B.1    Broadhurst, D.I.2    Atherton, H.J.3    Goodacre, R.4    Griffin, J.L.5
  • 22
    • 41049100247 scopus 로고    scopus 로고
    • Extending the breadth of metabolite profiling by gas chromatography coupled to mass spectrometry
    • Fiehn, O. (2008). Extending the breadth of metabolite profiling by gas chromatography coupled to mass spectrometry. Trends in Analytical Chemistry, 27, 261-269.
    • (2008) Trends in Analytical Chemistry , vol.27 , pp. 261-269
    • Fiehn, O.1
  • 23
    • 56449108866 scopus 로고    scopus 로고
    • Methodology for profiling the steroid metabolome in animal tissues using ultraperformance liquid chromatography-electrospray-time-of-flight mass spectrometry
    • Flores-Valverde, A. M., & Hill, E. M. (2008). Methodology for profiling the steroid metabolome in animal tissues using ultraperformance liquid chromatography-electrospray-time-of-flight mass spectrometry. Analytical Chemistry, 80, 8771-8779.
    • (2008) Analytical Chemistry , vol.80 , pp. 8771-8779
    • Flores-Valverde, A.M.1    Hill, E.M.2
  • 24
    • 77951821521 scopus 로고    scopus 로고
    • Disruption of the steroid metabolome in fish caused by exposure to the environmental estrogen 17 alpha-ethinylestradiol
    • Flores-Valverde, A. M., Horwood, J., & Hill, E. M. (2010). Disruption of the steroid metabolome in fish caused by exposure to the environmental estrogen 17 alpha-ethinylestradiol. Environmental Science and Technology, 44, 3552-3558.
    • (2010) Environmental Science and Technology , vol.44 , pp. 3552-3558
    • Flores-Valverde, A.M.1    Horwood, J.2    Hill, E.M.3
  • 26
    • 45949087351 scopus 로고    scopus 로고
    • Hydrophilic interaction and reversed-phase ultra-performance liquid chromatography TOF-MS for metabolomic analysis of Zucker rat urine
    • Gika, H. G., Theodoridis, G. A., & Wilson, I. D. (2008). Hydrophilic interaction and reversed-phase ultra-performance liquid chromatography TOF-MS for metabolomic analysis of Zucker rat urine. Journal of Separation Science, 31, 1598-1608.
    • (2008) Journal of Separation Science , vol.31 , pp. 1598-1608
    • Gika, H.G.1    Theodoridis, G.A.2    Wilson, I.D.3
  • 28
    • 68949157005 scopus 로고    scopus 로고
    • Mass spectrometry: From proteomics to metabolomics and lipidomics
    • Griffiths, W. J., & Wang, Y. Q. (2009). Mass spectrometry: From proteomics to metabolomics and lipidomics. Chemical Society Reviews, 38, 1882-1896.
    • (2009) Chemical Society Reviews , vol.38 , pp. 1882-1896
    • Griffiths, W.J.1    Wang, Y.Q.2
  • 29
    • 0032991929 scopus 로고    scopus 로고
    • Deconvolution gas chromatography mass spectrometry of urinary organic acids-potential for pattern recognition and automated identification of metabolic disorders
    • Halket, J. M., Przyborowska, A., Stein, S. E., Mallard, W. G., Down, S., & Chalmers, R. A. (1999). Deconvolution gas chromatography mass spectrometry of urinary organic acids-potential for pattern recognition and automated identification of metabolic disorders. Rapid Communications in Mass Spectrometry, 13, 279-284.
    • (1999) Rapid Communications in Mass Spectrometry , vol.13 , pp. 279-284
    • Halket, J.M.1    Przyborowska, A.2    Stein, S.E.3    Mallard, W.G.4    Down, S.5    Chalmers, R.A.6
  • 30
    • 43349100561 scopus 로고    scopus 로고
    • Towards high-throughput metabolomics using ultrahigh-field Fourier transform ion cyclotron resonance mass spectrometry
    • Han, J., Danell, R. M., Patel, J. R., Gumerov, D. R., Scarlett, C. O., Speir, J. P., et al. (2008). Towards high-throughput metabolomics using ultrahigh-field Fourier transform ion cyclotron resonance mass spectrometry. Metabolomics, 4, 128-140.
    • (2008) Metabolomics , vol.4 , pp. 128-140
    • Han, J.1    Danell, R.M.2    Patel, J.R.3    Gumerov, D.R.4    Scarlett, C.O.5    Speir, J.P.6
  • 31
    • 78650186960 scopus 로고    scopus 로고
    • Mass spectrometry-based technologies for high-throughput metabolomics
    • Han, J., Datla, R., Chan, S., & Borchers, C. H. (2009). Mass spectrometry-based technologies for high-throughput metabolomics. Bioanalysis, 1, 1665-1684.
    • (2009) Bioanalysis , vol.1 , pp. 1665-1684
    • Han, J.1    Datla, R.2    Chan, S.3    Borchers, C.H.4
  • 32
    • 78649317662 scopus 로고    scopus 로고
    • Abundant betaines in reef-building corals and ecological indicators of a photoprotective role
    • Hill, R. W., Li, C., Jones, A. D., Gunn, J. P., & Frade, P. R. (2010). Abundant betaines in reef-building corals and ecological indicators of a photoprotective role. Coral Reefs, 29, 869-880.
    • (2010) Coral Reefs , vol.29 , pp. 869-880
    • Hill, R.W.1    Li, C.2    Jones, A.D.3    Gunn, J.P.4    Frade, P.R.5
  • 33
    • 77957725564 scopus 로고    scopus 로고
    • Changes in diurnal patterns within the Populus transcriptome and metabolome in response to photoperiod variation
    • Hoffman, D. E., Jonsson, P., Bylesjo, M., Trygg, J., Antti, H., Eriksson, M. E., et al. (2010). Changes in diurnal patterns within the Populus transcriptome and metabolome in response to photoperiod variation. Plant, Cell and Environment, 33, 1298-1313.
    • (2010) Plant, Cell and Environment , vol.33 , pp. 1298-1313
    • Hoffman, D.E.1    Jonsson, P.2    Bylesjo, M.3    Trygg, J.4    Antti, H.5    Eriksson, M.E.6
  • 34
    • 43749087841 scopus 로고    scopus 로고
    • Human metabolic phenotype diversity and its association with diet and blood pressure
    • Holmes, E., Loo, R. L., Stamler, J., Bictash, M., Yap, I. K. S., Chan, Q., et al. (2008). Human metabolic phenotype diversity and its association with diet and blood pressure. Nature, 453, 396-400.
    • (2008) Nature , vol.453 , pp. 396-400
    • Holmes, E.1    Loo, R.L.2    Stamler, J.3    Bictash, M.4    Yap, I.K.S.5    Chan, Q.6
  • 35
    • 27544478275 scopus 로고    scopus 로고
    • Uniformity of ionization response of structurally diverse analytes using a chip-based nanoelectrospray ionization source
    • Hop, C., Chen, Y., & Yu, L. J. (2005). Uniformity of ionization response of structurally diverse analytes using a chip-based nanoelectrospray ionization source. Rapid Communications in Mass Spectrometry, 19, 3139-3142.
    • (2005) Rapid Communications in Mass Spectrometry , vol.19 , pp. 3139-3142
    • Hop, C.1    Chen, Y.2    Yu, L.J.3
  • 37
    • 79955008258 scopus 로고    scopus 로고
    • Metabolic fingerprinting as an indicator of biodiversity: Towards understanding inter-specific relationships among Homoscleromorpha sponges
    • Ivanišević, J., Thomas, O. P., Lejeusne, C., Chevaldonne, P., & Perez, T. (2011). Metabolic fingerprinting as an indicator of biodiversity: Towards understanding inter-specific relationships among Homoscleromorpha sponges. Metabolomics, 7, 289-304.
    • (2011) Metabolomics , vol.7 , pp. 289-304
    • Ivanišević, J.1    Thomas, O.P.2    Lejeusne, C.3    Chevaldonne, P.4    Perez, T.5
  • 39
    • 77954546853 scopus 로고    scopus 로고
    • Pathway analysis of the transcriptome and metabolome of salt sensitive and tolerant poplar species reveals evolutionary adaption of stress tolerance mechanisms
    • Janz, D., Behnke, K., Schnitzler, J. P., Kanawati, B., Schmitt-Kopplin, P., & Polle, A. (2010). Pathway analysis of the transcriptome and metabolome of salt sensitive and tolerant poplar species reveals evolutionary adaption of stress tolerance mechanisms. BMC Plant Biology, 10, 150.
    • (2010) BMC Plant Biology , vol.10 , pp. 150
    • Janz, D.1    Behnke, K.2    Schnitzler, J.P.3    Kanawati, B.4    Schmitt-Kopplin, P.5    Polle, A.6
  • 40
    • 43049181666 scopus 로고    scopus 로고
    • A metabolomics based approach to assessing the toxicity of the polyaromatic hydrocarbon pyrene to the earthworm Lumbricus rubellus
    • Jones, O. A. H., Spurgeon, D. J., Svendsen, C., & Griffin, J. L. (2008). A metabolomics based approach to assessing the toxicity of the polyaromatic hydrocarbon pyrene to the earthworm Lumbricus rubellus. Chemosphere, 71, 601-609.
    • (2008) Chemosphere , vol.71 , pp. 601-609
    • Jones, O.A.H.1    Spurgeon, D.J.2    Svendsen, C.3    Griffin, J.L.4
  • 41
    • 77955790535 scopus 로고    scopus 로고
    • Fourier transform mass spectrometry for metabolome analysis
    • Junot, C., Madalinski, G., Tabet, J. C., & Ezan, E. (2010). Fourier transform mass spectrometry for metabolome analysis. Analyst, 135, 2203-2219.
    • (2010) Analyst , vol.135 , pp. 2203-2219
    • Junot, C.1    Madalinski, G.2    Tabet, J.C.3    Ezan, E.4
  • 43
    • 42749084916 scopus 로고    scopus 로고
    • Improvement of sample throughput using fast gas chromatography mass-spectrometry for biochemical diagnosis of organic acid disorders
    • Kawana, S., Nakagawa, K., Hasegawa, Y., Kobayashi, H., & Yamaguchi, S. (2008). Improvement of sample throughput using fast gas chromatography mass-spectrometry for biochemical diagnosis of organic acid disorders. Clinica Chimica Acta, 392, 34-40.
    • (2008) Clinica Chimica Acta , vol.392 , pp. 34-40
    • Kawana, S.1    Nakagawa, K.2    Hasegawa, Y.3    Kobayashi, H.4    Yamaguchi, S.5
  • 45
    • 78650737804 scopus 로고    scopus 로고
    • Advances in structure elucidation of small molecules using mass spectrometry
    • Kind, T., & Fiehn, O. (2011). Advances in structure elucidation of small molecules using mass spectrometry. Bioanalytical Reviews, 2, 23-60.
    • (2011) Bioanalytical Reviews , vol.2 , pp. 23-60
    • Kind, T.1    Fiehn, O.2
  • 46
    • 72449186517 scopus 로고    scopus 로고
    • FiehnLib: Mass spectral and retention index libraries for metabolomics based on quadrupole and time-of-flight gas chromatography/mass spectrometry
    • Kind, T., Wohlgemuth, G., Lee, D. Y., Lu, Y., Palazoglu, M., Shahbaz, S., et al. (2009). FiehnLib: Mass spectral and retention index libraries for metabolomics based on quadrupole and time-of-flight gas chromatography/mass spectrometry. Analytical Chemistry, 81, 10038-10048.
    • (2009) Analytical Chemistry , vol.81 , pp. 10038-10048
    • Kind, T.1    Wohlgemuth, G.2    Lee, D.Y.3    Lu, Y.4    Palazoglu, M.5    Shahbaz, S.6
  • 47
    • 61849108205 scopus 로고    scopus 로고
    • A metabolomics approach to assessing phytotoxic effects on the green alga Scenedesmus vacuolatus
    • Kluender, C., Sans-Piche, F., Riedl, J., Altenburger, R., Hartig, C., Laue, G., et al. (2009). A metabolomics approach to assessing phytotoxic effects on the green alga Scenedesmus vacuolatus. Metabolomics, 5, 59-71.
    • (2009) Metabolomics , vol.5 , pp. 59-71
    • Kluender, C.1    Sans-Piche, F.2    Riedl, J.3    Altenburger, R.4    Hartig, C.5    Laue, G.6
  • 48
    • 80051704393 scopus 로고    scopus 로고
    • Quantitative metabolomics based on gas chromatography mass spectrometry: Status and perspectives
    • Koek, M. M., Jellema, R. H., van der Greef, J., Tas, A. C., & Hankemeier, T. (2011a). Quantitative metabolomics based on gas chromatography mass spectrometry: Status and perspectives. Metabolomics, 7, 307-328.
    • (2011) Metabolomics , vol.7 , pp. 307-328
    • Koek, M.M.1    Jellema, R.H.2    van der Greef, J.3    Tas, A.C.4    Hankemeier, T.5
  • 49
    • 79951726798 scopus 로고    scopus 로고
    • Semi-automated non-target processing in GC × GC-MS metabolomics analysis: Applicability for biomedical studies
    • Koek, M. M., van der Kloet, F. M., Kleemann, R., Kooistra, T., Verheij, E. R., & Hankemeier, T. (2011b). Semi-automated non-target processing in GC × GC-MS metabolomics analysis: Applicability for biomedical studies. Metabolomics, 7, 1-14.
    • (2011) Metabolomics , vol.7 , pp. 1-14
    • Koek, M.M.1    van der Kloet, F.M.2    Kleemann, R.3    Kooistra, T.4    Verheij, E.R.5    Hankemeier, T.6
  • 50
    • 67650930485 scopus 로고    scopus 로고
    • Semi-quantitative and structural metabolic phenotyping by direct infusion ion trap mass spectrometry and its application in genetical metabolomics
    • Koulman, A., Cao, M., Faville, M., Lane, G., Mace, W., & Rasmussen, S. (2009). Semi-quantitative and structural metabolic phenotyping by direct infusion ion trap mass spectrometry and its application in genetical metabolomics. Rapid Communications in Mass Spectrometry, 23, 2253-2263.
    • (2009) Rapid Communications in Mass Spectrometry , vol.23 , pp. 2253-2263
    • Koulman, A.1    Cao, M.2    Faville, M.3    Lane, G.4    Mace, W.5    Rasmussen, S.6
  • 51
    • 72949083047 scopus 로고    scopus 로고
    • Methodological considerations in the development of HPLC-MS methods for the analysis of rodent plasma for metabolomic studies
    • Lai, L., Michopoulos, F., Gika, H., Theodoridis, G., Wilkinson, R. W., Odedra, R., et al. (2010). Methodological considerations in the development of HPLC-MS methods for the analysis of rodent plasma for metabolomic studies. Molecular Biosystems, 6, 108-120.
    • (2010) Molecular Biosystems , vol.6 , pp. 108-120
    • Lai, L.1    Michopoulos, F.2    Gika, H.3    Theodoridis, G.4    Wilkinson, R.W.5    Odedra, R.6
  • 52
    • 79961071148 scopus 로고    scopus 로고
    • Exceptional production of both prodigiosin and cycloprodigiosin as major metabolic constituents by a novel marine bacterium, Zooshikella rubidus S1-1
    • Lee, J. S., Kim, Y. S., Park, S., Kim, J., Kang, S. J., Lee, M. H., et al. (2011). Exceptional production of both prodigiosin and cycloprodigiosin as major metabolic constituents by a novel marine bacterium, Zooshikella rubidus S1-1. Applied and Environmental Microbiology, 77, 4967-4973.
    • (2011) Applied and Environmental Microbiology , vol.77 , pp. 4967-4973
    • Lee, J.S.1    Kim, Y.S.2    Park, S.3    Kim, J.4    Kang, S.J.5    Lee, M.H.6
  • 53
    • 77953480233 scopus 로고    scopus 로고
    • Determination of betaine metabolites and dimethylsulfoniopropionate in coral tissues using liquid chromatography-time-of-flight mass spectrometry and stable isotope-labeled internal standards
    • Li, C., Hill, R. W., & Jones, A. D. (2010). Determination of betaine metabolites and dimethylsulfoniopropionate in coral tissues using liquid chromatography-time-of-flight mass spectrometry and stable isotope-labeled internal standards. Journal of Chromatography B, 878, 1809-1816.
    • (2010) Journal of Chromatography B , vol.878 , pp. 1809-1816
    • Li, C.1    Hill, R.W.2    Jones, A.D.3
  • 54
    • 33747815789 scopus 로고    scopus 로고
    • Metabolomics: Methodologies and applications in the environmental sciences
    • Lin, C. Y., Viant, M. R., & Tjeerdema, R. S. (2006). Metabolomics: Methodologies and applications in the environmental sciences. Journal of Pesticide Science, 31, 245-251.
    • (2006) Journal of Pesticide Science , vol.31 , pp. 245-251
    • Lin, C.Y.1    Viant, M.R.2    Tjeerdema, R.S.3
  • 56
    • 61849170023 scopus 로고    scopus 로고
    • (1)H NMR and GC/MS metabolomics of earthworm responses to sub-lethal DDT and endosulfan exposure
    • McKelvie, J. R., Yuk, J., Xu, Y. P., Simpson, A. J., & Simpson, M. J. (2009). (1)H NMR and GC/MS metabolomics of earthworm responses to sub-lethal DDT and endosulfan exposure. Metabolomics, 5, 84-94.
    • (2009) Metabolomics , vol.5 , pp. 84-94
    • McKelvie, J.R.1    Yuk, J.2    Xu, Y.P.3    Simpson, A.J.4    Simpson, M.J.5
  • 57
    • 34548718338 scopus 로고    scopus 로고
    • Shifts in the carbohydrate, polyol, and amino acid pools during rapid cold-hardening and diapause-associated cold-hardening in flesh flies (Sarcophaga crassipalpis): A metabolomic comparison
    • Michaud, M. R., & Denlinger, D. L. (2007). Shifts in the carbohydrate, polyol, and amino acid pools during rapid cold-hardening and diapause-associated cold-hardening in flesh flies (Sarcophaga crassipalpis): A metabolomic comparison. Journal of Comparative Physiology B, 177, 753-763.
    • (2007) Journal of Comparative Physiology B , vol.177 , pp. 753-763
    • Michaud, M.R.1    Denlinger, D.L.2
  • 58
    • 41949139870 scopus 로고    scopus 로고
    • Metabolomics reveals unique and shared metabolic changes in response to heat shock, freezing and desiccation in the Antarctic midge, Belgica antarctica
    • Michaud, M. R., Benoit, J. B., Lopez-Martinez, G., Elnitsky, M. A., Lee, R. E., & Denlinger, D. L. (2008). Metabolomics reveals unique and shared metabolic changes in response to heat shock, freezing and desiccation in the Antarctic midge, Belgica antarctica. Journal of Insect Physiology, 54, 645-655.
    • (2008) Journal of Insect Physiology , vol.54 , pp. 645-655
    • Michaud, M.R.1    Benoit, J.B.2    Lopez-Martinez, G.3    Elnitsky, M.A.4    Lee, R.E.5    Denlinger, D.L.6
  • 59
    • 65249146628 scopus 로고    scopus 로고
    • UPLC-MS-based analysis of human plasma for metabolomics using solvent precipitation or solid phase extraction
    • Michopoulos, F., Lai, L., Gika, H., Theodoridis, G., & Wilson, I. (2009). UPLC-MS-based analysis of human plasma for metabolomics using solvent precipitation or solid phase extraction. Journal of Proteome Research, 8, 2114-2121.
    • (2009) Journal of Proteome Research , vol.8 , pp. 2114-2121
    • Michopoulos, F.1    Lai, L.2    Gika, H.3    Theodoridis, G.4    Wilson, I.5
  • 60
    • 7744221296 scopus 로고    scopus 로고
    • Quantitative metabolic profiling by 1-dimensional H-1-NMR analyses: Application to plant genetics and functional genomics
    • Moing, A., Maucourt, M., Renaud, C., Gaudillere, M., Brouquisse, R., Lebouteiller, B., et al. (2004). Quantitative metabolic profiling by 1-dimensional H-1-NMR analyses: Application to plant genetics and functional genomics. Functional Plant Biology, 31, 889-902.
    • (2004) Functional Plant Biology , vol.31 , pp. 889-902
    • Moing, A.1    Maucourt, M.2    Renaud, C.3    Gaudillere, M.4    Brouquisse, R.5    Lebouteiller, B.6
  • 61
    • 34748869539 scopus 로고    scopus 로고
    • Standard reporting requirements for biological samples in metabolomics experiments: Environmental context
    • Morrison, N., Bearden, D., Bundy, J. G., Collette, T., Currie, F., Davey, M. P., et al. (2007). Standard reporting requirements for biological samples in metabolomics experiments: Environmental context. Metabolomics, 3, 203-210.
    • (2007) Metabolomics , vol.3 , pp. 203-210
    • Morrison, N.1    Bearden, D.2    Bundy, J.G.3    Collette, T.4    Currie, F.5    Davey, M.P.6
  • 62
    • 79960421231 scopus 로고    scopus 로고
    • New applications of mass spectrometry in lipid analysis
    • Murphy, R. C., & Gaskell, S. J. (2011). New applications of mass spectrometry in lipid analysis. Journal of Biological Chemistry, 286, 25427-25433.
    • (2011) Journal of Biological Chemistry , vol.286 , pp. 25427-25433
    • Murphy, R.C.1    Gaskell, S.J.2
  • 64
    • 65449138064 scopus 로고    scopus 로고
    • Analysis of the hibernation cycle using LC-MS-based metabolomics in ground squirrel liver
    • Nelson, C. J., Otis, J. P., Martin, S. L., & Carey, H. V. (2009). Analysis of the hibernation cycle using LC-MS-based metabolomics in ground squirrel liver. Physiological Genomics, 37, 43-51.
    • (2009) Physiological Genomics , vol.37 , pp. 43-51
    • Nelson, C.J.1    Otis, J.P.2    Martin, S.L.3    Carey, H.V.4
  • 65
    • 78649907918 scopus 로고    scopus 로고
    • Global analysis of circulating metabolites in hibernating ground squirrels
    • Nelson, C. J., Otis, J. P., & Carey, H. V. (2010). Global analysis of circulating metabolites in hibernating ground squirrels. Comparative Biochemistry and Physiology D, 5, 265-273.
    • (2010) Comparative Biochemistry and Physiology D , vol.5 , pp. 265-273
    • Nelson, C.J.1    Otis, J.P.2    Carey, H.V.3
  • 67
    • 38949166304 scopus 로고    scopus 로고
    • Application of metabolomics to genotype and phenotype discrimination of birch trees grown in a long-term open-field experiment
    • Ossipov, V., Ossipova, S., Bykov, V., Oksanen, E., Koricheva, J., & Haukioja, E. (2008). Application of metabolomics to genotype and phenotype discrimination of birch trees grown in a long-term open-field experiment. Metabolomics, 4, 39-51.
    • (2008) Metabolomics , vol.4 , pp. 39-51
    • Ossipov, V.1    Ossipova, S.2    Bykov, V.3    Oksanen, E.4    Koricheva, J.5    Haukioja, E.6
  • 68
    • 56149090838 scopus 로고    scopus 로고
    • Development and validation of a gas chromatography/mass spectrometry metabolomic platform for the global profiling of urinary metabolites
    • Pasikanti, K. K., Ho, P. C., & Chan, E. C. Y. (2008). Development and validation of a gas chromatography/mass spectrometry metabolomic platform for the global profiling of urinary metabolites. Rapid Communications in Mass Spectrometry, 22, 2984-2992.
    • (2008) Rapid Communications in Mass Spectrometry , vol.22 , pp. 2984-2992
    • Pasikanti, K.K.1    Ho, P.C.2    Chan, E.C.Y.3
  • 69
    • 0036388279 scopus 로고    scopus 로고
    • Metabolomics: The use of electrospray mass spectrometry coupled to reversed-phase liquid chromatography shows potential for the screening of rat urine in drug development
    • Plumb, R. S., Stumpf, C. L., Gorenstein, M. V., Castro-Perez, J. M., Dear, G. J., Anthony, M., et al. (2002). Metabolomics: The use of electrospray mass spectrometry coupled to reversed-phase liquid chromatography shows potential for the screening of rat urine in drug development. Rapid Communications in Mass Spectrometry, 16, 1991-1996.
    • (2002) Rapid Communications in Mass Spectrometry , vol.16 , pp. 1991-1996
    • Plumb, R.S.1    Stumpf, C.L.2    Gorenstein, M.V.3    Castro-Perez, J.M.4    Dear, G.J.5    Anthony, M.6
  • 70
    • 33749512402 scopus 로고    scopus 로고
    • The detection of phenotypic differences in the metabolic plasma profile of three strains of Zucker rats at 20 weeks of age using ultra-performance liquid chromatography/orthogonal acceleration time-of-flight mass spectrometry
    • Plumb, R. S., Johnson, K. A., Rainville, P., Shockcor, J. P., Williams, R., Granger, J. H., et al. (2006). The detection of phenotypic differences in the metabolic plasma profile of three strains of Zucker rats at 20 weeks of age using ultra-performance liquid chromatography/orthogonal acceleration time-of-flight mass spectrometry. Rapid Communications in Mass Spectrometry, 20, 2800-2806.
    • (2006) Rapid Communications in Mass Spectrometry , vol.20 , pp. 2800-2806
    • Plumb, R.S.1    Johnson, K.A.2    Rainville, P.3    Shockcor, J.P.4    Williams, R.5    Granger, J.H.6
  • 71
    • 79954515824 scopus 로고    scopus 로고
    • Metabolomics of microliter hemolymph samples enables an improved understanding of the combined metabolic and transcriptional responses of Daphnia magna to cadmium
    • Poynton, H. C., Taylor, N. S., Hicks, J., Colson, K., Chan, S. R., Clark, C., et al. (2011). Metabolomics of microliter hemolymph samples enables an improved understanding of the combined metabolic and transcriptional responses of Daphnia magna to cadmium. Environmental Science and Technology, 45, 3710-3717.
    • (2011) Environmental Science and Technology , vol.45 , pp. 3710-3717
    • Poynton, H.C.1    Taylor, N.S.2    Hicks, J.3    Colson, K.4    Chan, S.R.5    Clark, C.6
  • 72
    • 72849141575 scopus 로고    scopus 로고
    • Searching for signals in the noise: Metabolomics in chemical ecology
    • Prince, E. K., & Pohnert, G. (2010). Searching for signals in the noise: Metabolomics in chemical ecology. Analytical and Bioanalytical Chemistry, 396, 193-197.
    • (2010) Analytical and Bioanalytical Chemistry , vol.396 , pp. 193-197
    • Prince, E.K.1    Pohnert, G.2
  • 73
    • 43049167370 scopus 로고    scopus 로고
    • Development of GCxGC/TOF-MS metabolomics for use in ecotoxicological studies with invertebrates
    • Ralston-Hooper, K., Hopf, A., Oh, C., Zhang, X., Adamec, J., & Sepulveda, M. S. (2008). Development of GCxGC/TOF-MS metabolomics for use in ecotoxicological studies with invertebrates. Aquatic Toxicology, 88, 48-52.
    • (2008) Aquatic Toxicology , vol.88 , pp. 48-52
    • Ralston-Hooper, K.1    Hopf, A.2    Oh, C.3    Zhang, X.4    Adamec, J.5    Sepulveda, M.S.6
  • 74
    • 79960364802 scopus 로고    scopus 로고
    • Exploring matrix effects and quantification performance in metabolomics experiments using artificial biological gradients
    • Redestig, H., Kobayashi, M., Saito, K., & Kusano, M. (2011). Exploring matrix effects and quantification performance in metabolomics experiments using artificial biological gradients. Analytical Chemistry, 83, 5645-5651.
    • (2011) Analytical Chemistry , vol.83 , pp. 5645-5651
    • Redestig, H.1    Kobayashi, M.2    Saito, K.3    Kusano, M.4
  • 75
    • 77958131500 scopus 로고    scopus 로고
    • Terpenoid metabolite profiling in Sitka spruce identifies association of dehydroabietic acid, (+)-3-carene, and terpinolene with resistance against white pine weevil
    • Robert, J. A., Madilao, L. L., White, R., Yanchuk, A., King, J., & Bohlmann, J. (2010). Terpenoid metabolite profiling in Sitka spruce identifies association of dehydroabietic acid, (+)-3-carene, and terpinolene with resistance against white pine weevil. Botany-Botanique, 88, 810-820.
    • (2010) Botany-Botanique , vol.88 , pp. 810-820
    • Robert, J.A.1    Madilao, L.L.2    White, R.3    Yanchuk, A.4    King, J.5    Bohlmann, J.6
  • 77
    • 34248342618 scopus 로고    scopus 로고
    • Metabolite profiling of Douglas-fir (Pseudotsuga menziesii) field trials reveals strong environmental and weak genetic variation
    • Robinson, A. R., Ukrainetz, N. K., Kang, K. Y., & Mansfield, S. D. (2007). Metabolite profiling of Douglas-fir (Pseudotsuga menziesii) field trials reveals strong environmental and weak genetic variation. New Phytologist, 174, 762-773.
    • (2007) New Phytologist , vol.174 , pp. 762-773
    • Robinson, A.R.1    Ukrainetz, N.K.2    Kang, K.Y.3    Mansfield, S.D.4
  • 78
    • 30544454201 scopus 로고    scopus 로고
    • Metabolomics reviewed: A new "Omics" platform technology for systems biology and implications for natural products research
    • Rochfort, S. (2005). Metabolomics reviewed: A new "Omics" platform technology for systems biology and implications for natural products research. Journal of Natural Products, 68, 1813-1820.
    • (2005) Journal of Natural Products , vol.68 , pp. 1813-1820
    • Rochfort, S.1
  • 79
    • 52649173241 scopus 로고    scopus 로고
    • Contributions from metabolomics to fish research
    • Samuelsson, L. M., & Larsson, D. G. J. (2008). Contributions from metabolomics to fish research. Molecular Biosystems, 4, 974-979.
    • (2008) Molecular Biosystems , vol.4 , pp. 974-979
    • Samuelsson, L.M.1    Larsson, D.G.J.2
  • 81
    • 1542375217 scopus 로고    scopus 로고
    • Ecotoxicogenomics: The challenge of integrating genomics into aquatic and terrestrial ecotoxicology
    • Snape, J. R., Maund, S. J., Pickford, D. B., & Hutchinson, T. H. (2004). Ecotoxicogenomics: The challenge of integrating genomics into aquatic and terrestrial ecotoxicology. Aquatic Toxicology, 67, 143-154.
    • (2004) Aquatic Toxicology , vol.67 , pp. 143-154
    • Snape, J.R.1    Maund, S.J.2    Pickford, D.B.3    Hutchinson, T.H.4
  • 82
    • 68049109441 scopus 로고    scopus 로고
    • Metabolomic profiling of anionic metabolites by capillary electrophoresis mass spectrometry
    • Soga, T., Igarashi, K., Ito, C., Mizobuchi, K., Zimmermann, H. P., & Tomita, M. (2009). Metabolomic profiling of anionic metabolites by capillary electrophoresis mass spectrometry. Analytical Chemistry, 81, 6165-6174.
    • (2009) Analytical Chemistry , vol.81 , pp. 6165-6174
    • Soga, T.1    Igarashi, K.2    Ito, C.3    Mizobuchi, K.4    Zimmermann, H.P.5    Tomita, M.6
  • 83
    • 34347229424 scopus 로고    scopus 로고
    • Dynamic range and mass accuracy of wide-scan direct infusion nanoelectrospray Fourier transform ion cyclotron resonance mass spectrometry-based metabolomics increased by the spectral stitching method
    • Southam, A. D., Payne, T. G., Cooper, H. J., Arvanitis, T. N., & Viant, M. R. (2007). Dynamic range and mass accuracy of wide-scan direct infusion nanoelectrospray Fourier transform ion cyclotron resonance mass spectrometry-based metabolomics increased by the spectral stitching method. Analytical Chemistry, 79, 4595-4602.
    • (2007) Analytical Chemistry , vol.79 , pp. 4595-4602
    • Southam, A.D.1    Payne, T.G.2    Cooper, H.J.3    Arvanitis, T.N.4    Viant, M.R.5
  • 84
    • 79954523476 scopus 로고    scopus 로고
    • Metabolomics reveals target and off-target toxicities of a model organophosphate pesticide to roach (Rutilus rutilus): Implications for biomonitoring
    • Southam, A. D., Lange, A., Hines, A., Hill, E. M., Katsu, Y., Iguchi, T., et al. (2011). Metabolomics reveals target and off-target toxicities of a model organophosphate pesticide to roach (Rutilus rutilus): Implications for biomonitoring. Environmental Science and Technology, 45, 3759-3767.
    • (2011) Environmental Science and Technology , vol.45 , pp. 3759-3767
    • Southam, A.D.1    Lange, A.2    Hines, A.3    Hill, E.M.4    Katsu, Y.5    Iguchi, T.6
  • 86
    • 61849120270 scopus 로고    scopus 로고
    • A new approach to toxicity testing in Daphnia magna: Application of high throughput FT-ICR mass spectrometry metabolomics
    • Taylor, N. S., Weber, R. J. M., Southam, A. D., Payne, T. G., Hrydziuszko, O., Arvanitis, T. N., et al. (2009). A new approach to toxicity testing in Daphnia magna: Application of high throughput FT-ICR mass spectrometry metabolomics. Metabolomics, 5, 44-58.
    • (2009) Metabolomics , vol.5 , pp. 44-58
    • Taylor, N.S.1    Weber, R.J.M.2    Southam, A.D.3    Payne, T.G.4    Hrydziuszko, O.5    Arvanitis, T.N.6
  • 87
    • 77958485622 scopus 로고    scopus 로고
    • Discriminating between different acute chemical toxicities via changes in the Daphnid metabolome
    • Taylor, N. S., Weber, R. J. M., White, T. A., & Viant, M. R. (2010). Discriminating between different acute chemical toxicities via changes in the Daphnid metabolome. Toxicological Sciences, 118, 307-317.
    • (2010) Toxicological Sciences , vol.118 , pp. 307-317
    • Taylor, N.S.1    Weber, R.J.M.2    White, T.A.3    Viant, M.R.4
  • 88
    • 0037083636 scopus 로고    scopus 로고
    • Analysis of highly polar compounds of plant origin: Combination of hydrophilic interaction chromatography and electrospray ion trap mass spectrometry
    • Tolstikov, V. V., & Fiehn, O. (2002). Analysis of highly polar compounds of plant origin: Combination of hydrophilic interaction chromatography and electrospray ion trap mass spectrometry. Analytical Biochemistry, 301, 298-307.
    • (2002) Analytical Biochemistry , vol.301 , pp. 298-307
    • Tolstikov, V.V.1    Fiehn, O.2
  • 89
    • 0345168159 scopus 로고    scopus 로고
    • Monolithic silica-based capillary reversed-phase liquid chromatography/electrospray mass spectrometry for plant metabolomics
    • Tolstikov, V. V., Lommen, A., Nakanishi, K., Tanaka, N., & Fiehn, O. (2003). Monolithic silica-based capillary reversed-phase liquid chromatography/electrospray mass spectrometry for plant metabolomics. Analytical Chemistry, 75, 6737-6740.
    • (2003) Analytical Chemistry , vol.75 , pp. 6737-6740
    • Tolstikov, V.V.1    Lommen, A.2    Nakanishi, K.3    Tanaka, N.4    Fiehn, O.5
  • 90
    • 44449127723 scopus 로고    scopus 로고
    • Correlating the transcriptome, proteome, and metabolome in the environmental adaptation of a hyperthermophile
    • Trauger, S. A., Kalisak, E., Kalisiak, J., Morita, H., Weinberg, M. V., Menon, A. L., et al. (2008). Correlating the transcriptome, proteome, and metabolome in the environmental adaptation of a hyperthermophile. Journal of Proteome Research, 7, 1027-1035.
    • (2008) Journal of Proteome Research , vol.7 , pp. 1027-1035
    • Trauger, S.A.1    Kalisak, E.2    Kalisiak, J.3    Morita, H.4    Weinberg, M.V.5    Menon, A.L.6
  • 91
    • 77149124246 scopus 로고    scopus 로고
    • Integrating Omic technologies into aquatic ecological risk assessment and environmental monitoring: Hurdles, achievements, and future outlook
    • van Aggelen, G., Ankley, G. T., Baldwin, W. S., Bearden, D. W., Benson, W. H., Chipman, J. K., et al. (2010). Integrating Omic technologies into aquatic ecological risk assessment and environmental monitoring: Hurdles, achievements, and future outlook. Environmental Health Perspectives, 118, 1-5.
    • (2010) Environmental Health Perspectives , vol.118 , pp. 1-5
    • van Aggelen, G.1    Ankley, G.T.2    Baldwin, W.S.3    Bearden, D.W.4    Benson, W.H.5    Chipman, J.K.6
  • 92
    • 76349113800 scopus 로고    scopus 로고
    • Mixtures of similarly acting compounds in Daphnia magna: From gene to metabolite and beyond
    • Vandenbrouck, T., Jones, O. A. H., Dom, N., Griffin, J. L., & De Coen, W. (2010). Mixtures of similarly acting compounds in Daphnia magna: From gene to metabolite and beyond. Environment International, 36, 254-268.
    • (2010) Environment International , vol.36 , pp. 254-268
    • Vandenbrouck, T.1    Jones, O.A.H.2    Dom, N.3    Griffin, J.L.4    De Coen, W.5
  • 93
    • 34047109055 scopus 로고    scopus 로고
    • Metabolomics of aquatic organisms: The new 'omics' on the block
    • Viant, M. R. (2007). Metabolomics of aquatic organisms: The new 'omics' on the block. Marine Ecology Progress Series, 332, 301-306.
    • (2007) Marine Ecology Progress Series , vol.332 , pp. 301-306
    • Viant, M.R.1
  • 94
    • 52649126218 scopus 로고    scopus 로고
    • Recent developments in environmental metabolomics
    • Viant, M. R. (2008). Recent developments in environmental metabolomics. Molecular Biosystems, 4, 980-986.
    • (2008) Molecular Biosystems , vol.4 , pp. 980-986
    • Viant, M.R.1
  • 95
    • 0242628319 scopus 로고    scopus 로고
    • NMR-based metabolomics: A powerful approach for characterizing the effects of environmental stressors on organism health
    • Viant, M. R., Rosenblum, E. S., & Tjeerdema, R. S. (2003). NMR-based metabolomics: A powerful approach for characterizing the effects of environmental stressors on organism health. Environmental Science and Technology, 37, 4982-4989.
    • (2003) Environmental Science and Technology , vol.37 , pp. 4982-4989
    • Viant, M.R.1    Rosenblum, E.S.2    Tjeerdema, R.S.3
  • 98
    • 79958238506 scopus 로고    scopus 로고
    • Ecosystem, location, and climate effects on foliar secondary metabolites of lodge pole pine populations from central British Columbia
    • Wallis, C. M., Huber, D. P. W., & Lewis, K. J. (2011). Ecosystem, location, and climate effects on foliar secondary metabolites of lodge pole pine populations from central British Columbia. Journal of Chemical Ecology, 37, 607-621.
    • (2011) Journal of Chemical Ecology , vol.37 , pp. 607-621
    • Wallis, C.M.1    Huber, D.P.W.2    Lewis, K.J.3
  • 99
    • 0033982341 scopus 로고    scopus 로고
    • An NMR-based metabolomic investigation of the toxic effects of 3-trifluoromethyl-aniline on the earthworm Eisenia veneta
    • Warne, M. A., Lenz, E. M., Osborn, D., Weeks, J. M., & Nicholson, J. K. (2000). An NMR-based metabolomic investigation of the toxic effects of 3-trifluoromethyl-aniline on the earthworm Eisenia veneta. Biomarkers, 5, 56-72.
    • (2000) Biomarkers , vol.5 , pp. 56-72
    • Warne, M.A.1    Lenz, E.M.2    Osborn, D.3    Weeks, J.M.4    Nicholson, J.K.5
  • 100
    • 77958506191 scopus 로고    scopus 로고
    • MI-Pack: Increased confidence of metabolite identification in mass spectra by integrating accurate masses and metabolic pathways
    • Weber, R. J. M., & Viant, M. R. (2010). MI-Pack: Increased confidence of metabolite identification in mass spectra by integrating accurate masses and metabolic pathways. Chemometrics and Intelligent Laboratory Systems, 104, 75-82.
    • (2010) Chemometrics and Intelligent Laboratory Systems , vol.104 , pp. 75-82
    • Weber, R.J.M.1    Viant, M.R.2
  • 101
    • 79956129310 scopus 로고    scopus 로고
    • Characterization of isotopic abundance measurements in high resolution FT-ICR and Orbitrap mass spectra for improved confidence of metabolite identification
    • Weber, R. J. M., Southam, A. D., Sommer, U., & Viant, M. R. (2011). Characterization of isotopic abundance measurements in high resolution FT-ICR and Orbitrap mass spectra for improved confidence of metabolite identification. Analytical Chemistry, 83, 3737-3743.
    • (2011) Analytical Chemistry , vol.83 , pp. 3737-3743
    • Weber, R.J.M.1    Southam, A.D.2    Sommer, U.3    Viant, M.R.4
  • 102
    • 77954197821 scopus 로고    scopus 로고
    • High-throughput and multiplexed LC/MS/MRM method for targeted metabolomics
    • Wei, R., Li, G. D., & Seymour, A. B. (2010). High-throughput and multiplexed LC/MS/MRM method for targeted metabolomics. Analytical Chemistry, 82, 5527-5533.
    • (2010) Analytical Chemistry , vol.82 , pp. 5527-5533
    • Wei, R.1    Li, G.D.2    Seymour, A.B.3
  • 103
    • 77958098520 scopus 로고    scopus 로고
    • Fatty acid profiles as a potential lipidomic biomarker of exposure to brevetoxin for endangered Florida manatees (Trichechus manatus latirostris)
    • Wetzel, D. L., Reynolds, J. E., Sprinkel, J. M., Schwacke, L., Mercurio, P., & Rommel, S. A. (2010). Fatty acid profiles as a potential lipidomic biomarker of exposure to brevetoxin for endangered Florida manatees (Trichechus manatus latirostris). Science of the Total Environment, 408, 6124-6133.
    • (2010) Science of the Total Environment , vol.408 , pp. 6124-6133
    • Wetzel, D.L.1    Reynolds, J.E.2    Sprinkel, J.M.3    Schwacke, L.4    Mercurio, P.5    Rommel, S.A.6
  • 104
    • 35148894195 scopus 로고    scopus 로고
    • The potential role of wound-activated volatile release in the chemical defence of the brown alga Dictyota dichotoma: Blend recognition by marine herbivores
    • Wiesemeier, T., Hay, M., & Pohnert, G. (2007). The potential role of wound-activated volatile release in the chemical defence of the brown alga Dictyota dichotoma: Blend recognition by marine herbivores. Aquatic Sciences, 69, 403-412.
    • (2007) Aquatic Sciences , vol.69 , pp. 403-412
    • Wiesemeier, T.1    Hay, M.2    Pohnert, G.3
  • 105
    • 70350507673 scopus 로고    scopus 로고
    • The European Union's REACH regulation: A review of its history and requirements
    • Williams, E. S., Panko, J., & Paustenbach, D. J. (2009). The European Union's REACH regulation: A review of its history and requirements. Critical Reviews in Toxicology, 39, 553-575.
    • (2009) Critical Reviews in Toxicology , vol.39 , pp. 553-575
    • Williams, E.S.1    Panko, J.2    Paustenbach, D.J.3
  • 106
    • 69249084942 scopus 로고    scopus 로고
    • Toward a new US chemicals policy: Rebuilding the foundation to advance new science, green chemistry, and environmental health
    • Wilson, M. P., & Schwarzman, M. R. (2009). Toward a new US chemicals policy: Rebuilding the foundation to advance new science, green chemistry, and environmental health. Environmental Health Perspectives, 117, 1202-1209.
    • (2009) Environmental Health Perspectives , vol.117 , pp. 1202-1209
    • Wilson, M.P.1    Schwarzman, M.R.2
  • 107
    • 17444404226 scopus 로고    scopus 로고
    • High resolution "Ultra performance" liquid chromatography coupled to oa-TOF mass spectrometry as a tool for differential metabolic pathway profiling in functional genomic studies
    • Wilson, I. D., Nicholson, J. K., Castro-Perez, J., Granger, J. H., Johnson, K. A., Smith, B. W., et al. (2005a). High resolution "Ultra performance" liquid chromatography coupled to oa-TOF mass spectrometry as a tool for differential metabolic pathway profiling in functional genomic studies. Journal of Proteome Research, 4, 591-598.
    • (2005) Journal of Proteome Research , vol.4 , pp. 591-598
    • Wilson, I.D.1    Nicholson, J.K.2    Castro-Perez, J.3    Granger, J.H.4    Johnson, K.A.5    Smith, B.W.6
  • 109
    • 36148989929 scopus 로고    scopus 로고
    • High throughput tissue extraction protocol for NMR- and MS-based metabolomics
    • Wu, H., Southam, A. D., Hines, A., & Viant, M. R. (2008). High throughput tissue extraction protocol for NMR- and MS-based metabolomics. Analytical Biochemistry, 372, 204-212.
    • (2008) Analytical Biochemistry , vol.372 , pp. 204-212
    • Wu, H.1    Southam, A.D.2    Hines, A.3    Viant, M.R.4
  • 110
    • 77951621214 scopus 로고    scopus 로고
    • Global characterization of the photosynthetic glycerolipids from a marine diatom Stephanodiscus sp. by ultra performance liquid chromatography coupled with electrospray ionization-quadrupole-time of flight mass spectrometry
    • Xu, J. L., Chen, D. Y., Yan, X. J., Chen, J. J., & Zhou, C. X. (2010). Global characterization of the photosynthetic glycerolipids from a marine diatom Stephanodiscus sp. by ultra performance liquid chromatography coupled with electrospray ionization-quadrupole-time of flight mass spectrometry. Analytica Chimica Acta, 663, 60-68.
    • (2010) Analytica Chimica Acta , vol.663 , pp. 60-68
    • Xu, J.L.1    Chen, D.Y.2    Yan, X.J.3    Chen, J.J.4    Zhou, C.X.5
  • 111
    • 63649128102 scopus 로고    scopus 로고
    • Development of a robust and repeatable UPLC-MS method for the long-term metabolomic study of human serum
    • Zelena, E., Dunn, W. B., Broadhurst, D., Francis-McIntyre, S., Carroll, K. M., Begley, P., et al. (2009). Development of a robust and repeatable UPLC-MS method for the long-term metabolomic study of human serum. Analytical Chemistry, 81, 1357-1364.
    • (2009) Analytical Chemistry , vol.81 , pp. 1357-1364
    • Zelena, E.1    Dunn, W.B.2    Broadhurst, D.3    Francis-McIntyre, S.4    Carroll, K.M.5    Begley, P.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.