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Volumn 3, Issue JAN, 2013, Pages

Activation of somatostatin 2 receptors in the brain and the periphery induces opposite changes in circulating ghrelin levels: Functional implications

Author keywords

Cortistatin; Ghrelin cell; Somatostatin receptor agonists and antagonist; Somatostatin receptor subtypes; X A like cell

Indexed keywords


EID: 84874264433     PISSN: None     EISSN: 16642392     Source Type: Journal    
DOI: 10.3389/fendo.2012.00178     Document Type: Review
Times cited : (8)

References (170)
  • 1
    • 17944379112 scopus 로고    scopus 로고
    • Stomach is a major source of circulating ghrelin, and feeding state determines plasma ghrelin-like immunoreactivity levels in humans
    • Ariyasu, H., Takaya, K., Tagami, T., Ogawa, Y., Hosoda, K., Akamizu, T., et al. (2001). Stomach is a major source of circulating ghrelin, and feeding state determines plasma ghrelin-like immunoreactivity levels in humans. J. Clin. Endocrinol. Metab. 86, 4753-4758.
    • (2001) J. Clin. Endocrinol. Metab. , vol.86 , pp. 4753-4758
    • Ariyasu, H.1    Takaya, K.2    Tagami, T.3    Ogawa, Y.4    Hosoda, K.5    Akamizu, T.6
  • 2
    • 0036073405 scopus 로고    scopus 로고
    • Extent and direction of ghrelin transport across the blood-brain barrier is determined by its unique primary structure
    • Banks, W. A., Tschöp, M., Robinson, S. M., and Heiman, M. L. (2002). Extent and direction of ghrelin transport across the blood-brain barrier is determined by its unique primary structure. J. Pharmacol. Exp. Ther. 302, 822-827.
    • (2002) J. Pharmacol. Exp. Ther. , vol.302 , pp. 822-827
    • Banks, W.A.1    Tschöp, M.2    Robinson, S.M.3    Heiman, M.L.4
  • 3
    • 34548450155 scopus 로고    scopus 로고
    • Heterooligomerization of human dopamine receptor 2 and somatostatin receptor 2 co-immunoprecipitation and fluorescence resonance energy transfer analysis
    • Baragli, A., Alturaihi, H., Watt, H. L., Abdallah, A., and Kumar, U. (2007). Heterooligomerization of human dopamine receptor 2 and somatostatin receptor 2 co-immunoprecipitation and fluorescence resonance energy transfer analysis. Cell. Signal. 19,2304-2316.
    • (2007) Cell. Signal. , vol.19 , pp. 2304-2316
    • Baragli, A.1    Alturaihi, H.2    Watt, H.L.3    Abdallah, A.4    Kumar, U.5
  • 4
    • 0038030760 scopus 로고    scopus 로고
    • Ghrelin secretion in humans is sexually dimorphic, suppressed by somatostatin, and not affected by the ambient growth hormone levels
    • Barkan, A. L., Dimaraki, E. V., Jes-sup, S. K., Symons, K. V., Ermolenko, M., and Jaffe, C. A. (2003). Ghrelin secretion in humans is sexually dimorphic, suppressed by somatostatin, and not affected by the ambient growth hormone levels. J. Clin. Endocrinol. Metab. 88, 2180-2184.
    • (2003) J. Clin. Endocrinol. Metab. , vol.88 , pp. 2180-2184
    • Barkan, A.L.1    Dimaraki, E.V.2    Jes-sup, S.K.3    Symons, K.V.4    Ermolenko, M.5    Jaffe, C.A.6
  • 5
    • 0020363575 scopus 로고
    • SMS 201-995: a very potent and selective octapeptide analogue of somatostatin with prolonged action
    • Bauer, W., Briner, U., Doepfner, W., Haller, R., Huguenin, R., Marbach, P., et al. (1982). SMS 201-995: a very potent and selective octapeptide analogue of somatostatin with prolonged action. Life Sci. 31, 1133-1140.
    • (1982) Life Sci , vol.31 , pp. 1133-1140
    • Bauer, W.1    Briner, U.2    Doepfner, W.3    Haller, R.4    Huguenin, R.5    Marbach, P.6
  • 7
    • 0028247252 scopus 로고
    • Octreotide increases thresholds of colonic visceral perception in IBS patients without modifying muscle tone
    • Bradette, M., Delvaux, M., Stau-mont, G., Fioramonti, J., Bueno, L., and Frexinos, J. (1994). Octreotide increases thresholds of colonic visceral perception in IBS patients without modifying muscle tone. Dig. Dis. Sci. 39,1171-1178.
    • (1994) Dig. Dis. Sci. , vol.39 , pp. 1171-1178
    • Bradette, M.1    Delvaux, M.2    Stau-mont, G.3    Fioramonti, J.4    Bueno, L.5    Frexinos, J.6
  • 8
    • 0015914428 scopus 로고
    • Hypothalamic polypep-tide that inhibits the secretion of immunoreactive pituitary growth hormone
    • Brazeau, P., Vale, W., Burgus, R., Ling, N., Butcher, M., Rivier, J., et al. (1973). Hypothalamic polypep-tide that inhibits the secretion of immunoreactive pituitary growth hormone. Science 179, 77-79.
    • (1973) Science , vol.179 , pp. 77-79
    • Brazeau, P.1    Vale, W.2    Burgus, R.3    Ling, N.4    Butcher, M.5    Rivier, J.6
  • 9
    • 0030724520 scopus 로고    scopus 로고
    • Species differences between male rat and ram pituitary somatostatin receptors involved in the inhibition of growth hormone secretion
    • Briard, N., Dutour, A., Epelbaum, J., Sauze, N., Slama, A., and Oliver, C. (1997). Species differences between male rat and ram pituitary somatostatin receptors involved in the inhibition of growth hormone secretion. Eur. I Endocrinol. 137, 545-555.
    • (1997) Eur. I Endocrinol. , vol.137 , pp. 545-555
    • Briard, N.1    Dutour, A.2    Epelbaum, J.3    Sauze, N.4    Slama, A.5    Oliver, C.6
  • 11
  • 13
    • 0021341532 scopus 로고
    • Central nervous system regulation of adreno-corticotropin secretion: role of somatostatins
    • Brown, M. R., Rivier, C., and Vale, W. (1984). Central nervous system regulation of adreno-corticotropin secretion: role of somatostatins. Endocrinology 114, 1546-1549.
    • (1984) Endocrinology , vol.114 , pp. 1546-1549
    • Brown, M.R.1    Rivier, C.2    Vale, W.3
  • 14
    • 46849089935 scopus 로고    scopus 로고
    • Design and in vitro characterization of highly sst2-selective somatostatin antagonists suitable for radiotargeting
    • Cescato, R., Erchegyi, J., Waser, B., Pic-cand, V., Maecke, H. R., Rivier, J. E., et al. (2008). Design and in vitro characterization of highly sst2-selective somatostatin antagonists suitable for radiotargeting. J. Med. Chem. 51, 4030-4037.
    • (2008) J. Med. Chem. , vol.51 , pp. 4030-4037
    • Cescato, R.1    Erchegyi, J.2    Waser, B.3    Pic-cand, V.4    Maecke, H.R.5    Rivier, J.E.6
  • 15
    • 0038298292 scopus 로고    scopus 로고
    • Circulating ghrelin levels in patients with pancreatic and gastrointestinal neu-roendocrine tumors: identification of one pancreatic ghrelinoma
    • Corbetta, S., Peracchi, M., Cap-piello, V., Lania, A., Lauri, E., Vago, L., et al. (2003). Circulating ghrelin levels in patients with pancreatic and gastrointestinal neu-roendocrine tumors: identification of one pancreatic ghrelinoma. J. Clin. Endocrinol. Metab. 88, 3117-3120.
    • (2003) J. Clin. Endocrinol. Metab. , vol.88 , pp. 3117-3120
    • Corbetta, S.1    Peracchi, M.2    Cap-piello, V.3    Lania, A.4    Lauri, E.5    Vago, L.6
  • 16
    • 84857376637 scopus 로고    scopus 로고
    • Somatostatin dramatically stimulates growth hormone release from primate somatotrophs acting at low doses via somatostatin receptor 5 and cyclic AMP
    • Cordoba-Chacon, J., Gahete, M. D., Culler, M. D., Castano, J. P., Kine-man, R. D., and Luque, R. M. (2012). Somatostatin dramatically stimulates growth hormone release from primate somatotrophs acting at low doses via somatostatin receptor 5 and cyclic AMP. J. Neuroendocrinol. 24, 453-463.
    • (2012) J. Neuroendocrinol. , vol.24 , pp. 453-463
    • Cordoba-Chacon, J.1    Gahete, M.D.2    Culler, M.D.3    Castano, J.P.4    Kine-man, R.D.5    Luque, R.M.6
  • 17
    • 82355190866 scopus 로고    scopus 로고
    • Cortistatin is not a somatostatin analogue but stimulates prolactin release, and inhibits GH and ACTH in a gender-dependent fashion: potential role of ghrelin
    • Cordoba-Chacon, J., Gahete, M. D., Pozo-Salas, A. I., Martinez-Fuentes, A. J., de Lecea, L., Gracia-Navarro, E, et al. (2011). Cortistatin is not a somatostatin analogue but stimulates prolactin release, and inhibits GH and ACTH in a gender-dependent fashion: potential role of ghrelin. Endocrinology 152, 4800-4812.
    • (2011) Endocrinology , vol.152 , pp. 4800-4812
    • Cordoba-Chacon, J.1    Gahete, M.D.2    Pozo-Salas, A.I.3    Martinez-Fuentes, A.J.4    de Lecea, L.5    Gracia-Navarro, E.6
  • 19
    • 0017696972 scopus 로고
    • Evidence that some intrinsic neurons of the intestine contain somatostatin
    • Costa, M., Patel, Y., Furness, J. B., and Arimura, A. (1977). Evidence that some intrinsic neurons of the intestine contain somatostatin. Neurosci. Lett. 6,215-222.
    • (1977) Neurosci. Lett. , vol.6 , pp. 215-222
    • Costa, M.1    Patel, Y.2    Furness, J.B.3    Arimura, A.4
  • 21
    • 0035433977 scopus 로고    scopus 로고
    • A preprandial rise in plasma ghrelin levels suggests a role in meal initiation in humans
    • Cummings, D. E., Purnell, J. Q., Frayo, R. S., Schmidova, K., Wisse, B. E., and Weigle, D. S. (2001). A preprandial rise in plasma ghrelin levels suggests a role in meal initiation in humans. Diabetes. 50, 1714-1719.
    • (2001) Diabetes , vol.50 , pp. 1714-1719
    • Cummings, D.E.1    Purnell, J.Q.2    Frayo, R.S.3    Schmidova, K.4    Wisse, B.E.5    Weigle, D.S.6
  • 24
    • 84856715703 scopus 로고    scopus 로고
    • High constitutive activity is an intrinsic feature of ghrelin receptor protein: a study with a functional monomeric GHS-R1a receptor reconstituted in lipid discs
    • Damian, M., Marie, J., Leyris, J. P., Fehrentz, J. A., Verdie, P., Martinez, J., et al. (2012). High constitutive activity is an intrinsic feature of ghrelin receptor protein: a study with a functional monomeric GHS-R1a receptor reconstituted in lipid discs. J. Biol. Chem. 287, 3630-3641.
    • (2012) J. Biol. Chem. , vol.287 , pp. 3630-3641
    • Damian, M.1    Marie, J.2    Leyris, J.P.3    Fehrentz, J.A.4    Verdie, P.5    Martinez, J.6
  • 25
    • 0036787457 scopus 로고    scopus 로고
    • The role of the gastric afferent vagal nerve in ghrelin-induced feeding and growth hormone secretion in rats
    • Date, Y., Murakami, N., Toshinai, K., Matsukura, S., Niijima, A., Mat-suo, H., et al. (2002). The role of the gastric afferent vagal nerve in ghrelin-induced feeding and growth hormone secretion in rats. Gastroen-terology 123, 1120-1128.
    • (2002) Gastroen-terology , vol.123 , pp. 1120-1128
    • Date, Y.1    Murakami, N.2    Toshinai, K.3    Matsukura, S.4    Niijima, A.5    Mat-suo, H.6
  • 26
    • 29844444877 scopus 로고    scopus 로고
    • International Union of Pharmacology. LVI. Ghrelin receptor nomenclature, distribution, and function
    • Davenport, A. P., Bonner, T. I., Foord, S. M., Harmar, A. J., Neubig, R. R., Pin, J. P., et al. (2005). International Union of Pharmacology. LVI. Ghrelin receptor nomenclature, distribution, and function. Pharmacol Rev. 57, 541-546.
    • (2005) Pharmacol Rev , vol.57 , pp. 541-546
    • Davenport, A.P.1    Bonner, T.I.2    Foord, S.M.3    Harmar, A.J.4    Neubig, R.R.5    Pin, J.P.6
  • 29
    • 0035117145 scopus 로고    scopus 로고
    • Cortistatin, but not somatostatin, binds to growth hormone secretagogue (GHS) receptors of human pituitary gland
    • Deghenghi, R., Papotti, M., Ghigo, E., and Muccioli, G. (2001b). Cortistatin, but not somatostatin, binds to growth hormone secretagogue (GHS) receptors of human pituitary gland. J. Endocrinol Invest. 24, RC1- RC33.
    • (2001) J. Endocrinol Invest. , vol.24
    • Deghenghi, R.1    Papotti, M.2    Ghigo, E.3    Muccioli, G.4
  • 30
    • 0035083390 scopus 로고    scopus 로고
    • Somatostatin octapeptides (lanreotide, octreotide, vapreotide, and their analogs) share the growth hormone-releasing peptide receptor in the human pituitary gland
    • Deghenghi, R., Papotti, M., Ghigo, E., Muccioli, G., and Locatelli, V. (2001c). Somatostatin octapeptides (lanreotide, octreotide, vapreotide, and their analogs) share the growth hormone-releasing peptide receptor in the human pituitary gland. Endocrine 14, 29-33.
    • (2001) Endocrine , vol.14 , pp. 29-33
    • Deghenghi, R.1    Papotti, M.2    Ghigo, E.3    Muccioli, G.4    Locatelli, V.5
  • 31
    • 55649108863 scopus 로고    scopus 로고
    • Glucagon-like peptide-1, but not glucose-dependent insulinotropic peptide, inhibits glucagon secretion via somatostatin (receptor subtype 2) in the perfused rat pancreas
    • de Heer, J., Rasmussen, C., Coy, D. H., and Holst, J. J. (2008). Glucagon-like peptide-1, but not glucose-dependent insulinotropic peptide, inhibits glucagon secretion via somatostatin (receptor subtype 2) in the perfused rat pancreas. Diabetologia 51,2263-2270.
    • (2008) Diabetologia , vol.51 , pp. 2263-2270
    • de Heer, J.1    Rasmussen, C.2    Coy, D.H.3    Holst, J.J.4
  • 32
    • 34547652457 scopus 로고    scopus 로고
    • Secretion of ghrelin from rat stomach ghrelin cells in response to local microinfusion of candidate messenger compounds: a microdialysis study
    • de la Cour, C. D., Norlen, P., and Hakanson, R. (2007). Secretion of ghrelin from rat stomach ghrelin cells in response to local microinfusion of candidate messenger compounds: a microdialysis study. Regul Pept. 143, 118-126.
    • (2007) Regul Pept , vol.143 , pp. 118-126
    • de la Cour, C.D.1    Norlen, P.2    Hakanson, R.3
  • 36
    • 0036268616 scopus 로고    scopus 로고
    • The GH-releasing effect of ghrelin, a natural GH secretagogue, is only blunted by the infusion of exogenous somatostatin in humans
    • Di Vito, L., Broglio, F., Benso, A., Got-tero, C., Prodam, F., Papotti, M., et al. (2002). The GH-releasing effect of ghrelin, a natural GH secretagogue, is only blunted by the infusion of exogenous somatostatin in humans. Clin. Endocrinol (Oxf.) 56, 643-648.
    • (2002) Clin. Endocrinol (Oxf.) , vol.56 , pp. 643-648
    • Di Vito, L.1    Broglio, F.2    Benso, A.3    Got-tero, C.4    Prodam, F.5    Papotti, M.6
  • 39
    • 65649136518 scopus 로고    scopus 로고
    • Novel, potent, and radio-iodinatable somatostatin receptor 1 (sst1) selective analogues
    • Erchegyi, J., Cescato, R., Grace, C. R., Waser, B., Piccand, V., Hoyer, D., et al. (2009). Novel, potent, and radio-iodinatable somatostatin receptor 1 (sst1) selective analogues. J. Med. Chem. 52, 2733-2746.
    • (2009) J. Med. Chem. , vol.52 , pp. 2733-2746
    • Erchegyi, J.1    Cescato, R.2    Grace, C.R.3    Waser, B.4    Piccand, V.5    Hoyer, D.6
  • 40
    • 42949169479 scopus 로고    scopus 로고
    • Ring size of somatostatin analogues (ODT-8) modulates receptor selectivity and binding affinity
    • Erchegyi, J., Grace, C. R., Samant, M., Cescato, R., Piccand, V., Riek, R., et al. (2008). Ring size of somatostatin analogues (ODT-8) modulates receptor selectivity and binding affinity. J. Med. Chem. 51, 2668-2675.
    • (2008) J. Med. Chem. , vol.51 , pp. 2668-2675
    • Erchegyi, J.1    Grace, C.R.2    Samant, M.3    Cescato, R.4    Piccand, V.5    Riek, R.6
  • 41
    • 0033737866 scopus 로고    scopus 로고
    • Distribution and characterisation of somatostatin receptor mRNA and binding sites in the brain and periphery
    • Fehlmann, D., Langenegger, D., Schuep-bach, E., Siehler, S., Feuerbach, D., and Hoyer, D. (2000). Distribution and characterisation of somatostatin receptor mRNA and binding sites in the brain and periphery. J. Physiol. Paris 94,265-281.
    • (2000) J. Physiol. Paris , vol.94 , pp. 265-281
    • Fehlmann, D.1    Langenegger, D.2    Schuep-bach, E.3    Siehler, S.4    Feuerbach, D.5    Hoyer, D.6
  • 42
    • 0025223234 scopus 로고
    • Central somatostatin: a re-examination of its effects on feeding
    • Feifel, D., and Vaccarino, F. J. (1990). Central somatostatin: a re-examination of its effects on feeding. Brain Res. 535, 189-194.
    • (1990) Brain Res , vol.535 , pp. 189-194
    • Feifel, D.1    Vaccarino, F.J.2
  • 43
    • 80052472127 scopus 로고    scopus 로고
    • Ghrelin and obestatin modulate growth hormone-releasing hormone release and synaptic inputs onto growth hormone-releasing hormone neurons
    • Feng, D. D., Yang, S. K., Loudes, C., Simon, A., Al-Sarraf, T., Culler, M., et al. (2011). Ghrelin and obestatin modulate growth hormone-releasing hormone release and synaptic inputs onto growth hormone-releasing hormone neurons. Eur. J. Neurosci. 34, 732-744.
    • (2011) Eur. J. Neurosci. , vol.34 , pp. 732-744
    • Feng, D.D.1    Yang, S.K.2    Loudes, C.3    Simon, A.4    Al-Sarraf, T.5    Culler, M.6
  • 44
    • 0019824917 scopus 로고
    • The immunocytochemical localization of somatostatin-containing neurons in the rat central nervous system
    • Finley, J. C., Maderdrut, J. L., Roger, L. J., and Petrusz, P. (1981). The immunocytochemical localization of somatostatin-containing neurons in the rat central nervous system. Neu-roscience 6,2173-2192.
    • (1981) Neu-roscience , vol.6 , pp. 2173-2192
    • Finley, J.C.1    Maderdrut, J.L.2    Roger, L.J.3    Petrusz, P.4
  • 45
    • 57349142534 scopus 로고    scopus 로고
    • Reassessment of sst2 somatostatin receptor expression in human normal and neo-plastic tissues using the novel rabbit monoclonal antibody UMB-1
    • Fischer, T., Doll, C., Jacobs, S., Kolodziej, A., Stumm, R., and Schulz, S. (2008). Reassessment of sst2 somatostatin receptor expression in human normal and neo-plastic tissues using the novel rabbit monoclonal antibody UMB-1. J. Clin. Endocrinol Metab. 93, 4519-4524.
    • (2008) J. Clin. Endocrinol Metab. , vol.93 , pp. 4519-4524
    • Fischer, T.1    Doll, C.2    Jacobs, S.3    Kolodziej, A.4    Stumm, R.5    Schulz, S.6
  • 48
    • 74749103533 scopus 로고    scopus 로고
    • Metabolic regulation of ghrelin O-acyl transferase (GOAT) expression in the mouse hypothala-mus, pituitary, and stomach
    • Gahete, M. D., Cordoba-Chacon, J., Salvatori, R., Castano, J. P., Kine-man, R. D., and Luque, R. M. (2010b). Metabolic regulation of ghrelin O-acyl transferase (GOAT) expression in the mouse hypothala-mus, pituitary, and stomach. Mol. Cell Endocrinol. 317, 154-160.
    • (2010) Mol. Cell Endocrinol. , vol.317 , pp. 154-160
    • Gahete, M.D.1    Cordoba-Chacon, J.2    Salvatori, R.3    Castano, J.P.4    Kine-man, R.D.5    Luque, R.M.6
  • 49
    • 0345440005 scopus 로고    scopus 로고
    • Diurnal variations and sleep deprivation-induced changes in rat hypothalamic GHRH and somatostatin contents
    • Gardi, J., Obal, F. Jr., Fang, J., Zhang, J., and Krueger, J. M. (1999). Diurnal variations and sleep deprivation-induced changes in rat hypothalamic GHRH and somatostatin contents. Am. J. Physiol. 277, R1339-R1344.
    • (1999) Am. J. Physiol. , vol.277
    • Gardi, J.1    Obal Jr, F.2    Fang, J.3    Zhang, J.4    Krueger, J.M.5
  • 50
    • 84861665921 scopus 로고    scopus 로고
    • Peptide receptor radionu-clide therapy with somatostatin analogues in neuroendocrine tumors
    • Giovacchini, G., Nicolas, G., and Forrer, F. (2012). Peptide receptor radionu-clide therapy with somatostatin analogues in neuroendocrine tumors. Anticancer Agents Med. Chem. 12, 526-542.
    • (2012) Anticancer Agents Med. Chem. , vol.12 , pp. 526-542
    • Giovacchini, G.1    Nicolas, G.2    Forrer, F.3
  • 51
    • 57749084282 scopus 로고    scopus 로고
    • Influence of chronic undernutrition and leptin on GOAT mRNA levels in rat stomach mucosa
    • Gonzalez, C. R., Vazquez, M. J., Lopez, M., andDieguez, C. (2008). Influence of chronic undernutrition and leptin on GOAT mRNA levels in rat stomach mucosa. J. Mol Endocrinol. 41, 415-421.
    • (2008) J. Mol Endocrinol. , vol.41 , pp. 415-421
    • Gonzalez, C.R.1    Vazquez, M.J.2    Lopez, M.3    Dieguez, C.4
  • 52
    • 43549110929 scopus 로고    scopus 로고
    • Emergence of cortistatin as a new immunomodulatory factor with therapeutic potential in immune disorders
    • Gonzalez-Rey, E., and Delgado, M. (2008). Emergence of cortistatin as a new immunomodulatory factor with therapeutic potential in immune disorders. Mol Cell Endocrinol. 286, 135-140.
    • (2008) Mol Cell Endocrinol , vol.286 , pp. 135-140
    • Gonzalez-Rey, E.1    Delgado, M.2
  • 53
    • 33746674999 scopus 로고    scopus 로고
    • Novel sst2-selective somatostatin agonists Three-dimensional consensus structure by NMR
    • Grace, C. R., Erchegyi, J., Koerber, S. C., Reubi, J. C., Rivier, J., and Riek, R. (2006). Novel sst2-selective somatostatin agonists. Three-dimensional consensus structure by NMR. J. Med. Chem. 49,4487-4496.
    • (2006) J. Med. Chem. , vol.49 , pp. 4487-4496
    • Grace, C.R.1    Erchegyi, J.2    Koerber, S.C.3    Reubi, J.C.4    Rivier, J.5    Riek, R.6
  • 54
    • 42949155714 scopus 로고    scopus 로고
    • Ring size in octreotide amide modulates differently agonist versus antagonist binding affinity and selectivity
    • Grace, C. R., Erchegyi, J., Samant, M., Cescato, R., Piccand, V., Riek, R., et al. (2008). Ring size in octreotide amide modulates differently agonist versus antagonist binding affinity and selectivity. J. Med. Chem. 51, 2676-2681.
    • (2008) J. Med. Chem. , vol.51 , pp. 2676-2681
    • Grace, C.R.1    Erchegyi, J.2    Samant, M.3    Cescato, R.4    Piccand, V.5    Riek, R.6
  • 55
  • 56
    • 79952473901 scopus 로고    scopus 로고
    • Neuroen-docrinology: a short historical review
    • Guillemin, R. (2011). Neuroen-docrinology: a short historical review. Ann. N Y Acad. Sci. 1220, 1-5.
    • (2011) Ann. N Y Acad. Sci. , vol.1220 , pp. 1-5
    • Guillemin, R.1
  • 58
    • 0033608746 scopus 로고    scopus 로고
    • Corticotropin-releasing factor receptor type 1 mediates emotional stress-induced inhibition of food intake and behavioral changes in rats
    • Hotta, M., Shibasaki, T., Arai, K., and Demura, H. (1999). Corticotropin-releasing factor receptor type 1 mediates emotional stress-induced inhibition of food intake and behavioral changes in rats. Brain Res. 823, 221-225.
    • (1999) Brain Res , vol.823 , pp. 221-225
    • Hotta, M.1    Shibasaki, T.2    Arai, K.3    Demura, H.4
  • 59
    • 0031042715 scopus 로고    scopus 로고
    • Somatostatin release as measured by in vivo microdialysis: circadian variation and effect of prolonged food deprivation
    • Ishikawa, M., Mizobuchi, M., Taka-hashi, H., Bando, H., and Saito, S. (1997). Somatostatin release as measured by in vivo microdialysis: circadian variation and effect of prolonged food deprivation. Brain Res. 749,226-231.
    • (1997) Brain Res , vol.749 , pp. 226-231
    • Ishikawa, M.1    Mizobuchi, M.2    Taka-hashi, H.3    Bando, H.4    Saito, S.5
  • 60
    • 18744391060 scopus 로고    scopus 로고
    • Ghrelin expression in islet cell tumors: augmented expression of ghrelin in a case of glucagonoma with multiple endocrine neoplasm type I
    • Iwakura, H., Hosoda, K., Doi, R., Komoto, I., Nishimura, H., Son, C., et al. (2002). Ghrelin expression in islet cell tumors: augmented expression of ghrelin in a case of glucagonoma with multiple endocrine neoplasm type I. J. Clin. Endocrinol. Metab. 87, 4885-4888.
    • (2002) J. Clin. Endocrinol. Metab. , vol.87 , pp. 4885-4888
    • Iwakura, H.1    Hosoda, K.2    Doi, R.3    Komoto, I.4    Nishimura, H.5    Son, C.6
  • 63
    • 0021710551 scopus 로고
    • Immunohistochemi-cal distribution of somatostatin-like immunoreactivity in the central nervous system of the adult rat
    • Johansson, O., Hokfelt, T., and Elde, R. P. (1984). Immunohistochemi-cal distribution of somatostatin-like immunoreactivity in the central nervous system of the adult rat. Neuro-science 13,265-339.
    • (1984) Neuro-science , vol.13 , pp. 265-339
    • Johansson, O.1    Hokfelt, T.2    Elde, R.P.3
  • 64
    • 84855369905 scopus 로고    scopus 로고
    • Mouse ghrelin-O-acyltransferase (GOAT) plays a critical role in bile acid reabsorption
    • Kang, K., Schmahl, J., Lee, J. M., Garcia, K., Patil, K, Chen, A., et al. (2012). Mouse ghrelin-O-acyltransferase (GOAT) plays a critical role in bile acid reabsorption. FASEB J.26,259-271.
    • (2012) FASEB J , vol.26 , pp. 259-271
    • Kang, K.1    Schmahl, J.2    Lee, J.M.3    Garcia, K.4    Patil, K.5    Chen, A.6
  • 65
    • 0042200265 scopus 로고    scopus 로고
    • Changes in ghrelin and ghrelin receptor expression according to feeding status
    • Kim, M. S., Yoon, C. Y., Park, K. H., Shin, C. S., Park, K. S., Kim, S. Y., et al. (2003). Changes in ghrelin and ghrelin receptor expression according to feeding status. Neuroreport 14, 1317-1320.
    • (2003) Neuroreport , vol.14 , pp. 1317-1320
    • Kim, M.S.1    Yoon, C.Y.2    Park, K.H.3    Shin, C.S.4    Park, K.S.5    Kim, S.Y.6
  • 66
    • 34548083739 scopus 로고    scopus 로고
    • Evidence that ghrelin is as potent as growth hormone (GH)-releasing hormone (GHRH) in releasing GH from primary pituitary cell cultures of a nonhuman primate (Papio anubis), acting through intracellular signaling pathways distinct from GHRH
    • Kineman, R. D., and Luque, R. M. (2007). Evidence that ghrelin is as potent as growth hormone (GH)-releasing hormone (GHRH) in releasing GH from primary pituitary cell cultures of a nonhuman primate (Papio anubis), acting through intracellular signaling pathways distinct from GHRH. Endocrinology 148,4440-4449.
    • (2007) Endocrinology , vol.148 , pp. 4440-4449
    • Kineman, R.D.1    Luque, R.M.2
  • 67
    • 0033540056 scopus 로고    scopus 로고
    • Ghrelin is a growth-hormone-releasing acylated peptide from stomach
    • Kojima, M., Hosoda, H., Date, Y., Nakazato, M., Matsuo, H., and Kan-gawa, K. (1999). Ghrelin is a growth-hormone-releasing acylated peptide from stomach. Nature 402, 656-660.
    • (1999) Nature , vol.402 , pp. 656-660
    • Kojima, M.1    Hosoda, H.2    Date, Y.3    Nakazato, M.4    Matsuo, H.5    Kan-gawa, K.6
  • 68
    • 0035320623 scopus 로고    scopus 로고
    • Ghrelin: discovery of the natural endogenous ligand for the growth hormone secre-tagogue receptor
    • Kojima, M., Hosoda, H., Matsuo, H., and Kangawa, K. (2001). Ghrelin: discovery of the natural endogenous ligand for the growth hormone secre-tagogue receptor. Trends Endocrinol. Metab. 12, 118-122.
    • (2001) Trends Endocrinol. Metab. , vol.12 , pp. 118-122
    • Kojima, M.1    Hosoda, H.2    Matsuo, H.3    Kangawa, K.4
  • 69
    • 15544385058 scopus 로고    scopus 로고
    • Ghrelin: structure and function
    • Kojima, M., and Kangawa, K. (2005). Ghrelin: structure and function. Physiol Rev. 85, 495-522.
    • (2005) Physiol Rev , vol.85 , pp. 495-522
    • Kojima, M.1    Kangawa, K.2
  • 70
    • 81755173376 scopus 로고    scopus 로고
    • The discovery of ghrelin: with a little luck and great passion
    • Kojima, M., and Kangawa, K. (2011). The discovery of ghrelin: with a little luck and great passion. Peptides 32, 2153-2154.
    • (2011) Peptides , vol.32 , pp. 2153-2154
    • Kojima, M.1    Kangawa, K.2
  • 71
    • 0032748271 scopus 로고    scopus 로고
    • Somatostatin receptor subtype 1 modulates basal inhibition of growth hormone release in somatotrophs
    • Kreienkamp, H. J., Akgun, E., Baumeis-ter, H., Meyerhof, W., and Richter, D. (1999). Somatostatin receptor subtype 1 modulates basal inhibition of growth hormone release in somatotrophs. FEBS Lett. 462, 464-466.
    • (1999) FEBS Lett , vol.462 , pp. 464-466
    • Kreienkamp, H.J.1    Akgun, E.2    Baumeis-ter, H.3    Meyerhof, W.4    Richter, D.5
  • 73
    • 80052583940 scopus 로고    scopus 로고
    • The expression of ghrelin O-acyltransferase (GOAT) in human tissues
    • Lim, C. T., Kola, B., Grossman, A., and Korbonits, M. (2011). The expression of ghrelin O-acyltransferase (GOAT) in human tissues. Endocr. J. 8, 707-710.
    • (2011) Endocr. J. , vol.8 , pp. 707-710
    • Lim, C.T.1    Kola, B.2    Grossman, A.3    Korbonits, M.4
  • 74
    • 71349087067 scopus 로고    scopus 로고
    • Cortistatin attenuates vascular calcification in rats
    • Liu, Y., Zhou, Y. B., Zhang, G. G., Cai, Y., Duan, X. H., Teng, X., et al. (2010). Cortistatin attenuates vascular calcification in rats. Regul. Pept. 159,35-43.
    • (2010) Regul. Pept. , vol.159 , pp. 35-43
    • Liu, Y.1    Zhou, Y.B.2    Zhang, G.G.3    Cai, Y.4    Duan, X.H.5    Teng, X.6
  • 75
    • 0030860441 scopus 로고    scopus 로고
    • Somatostatin inhibits gastrin release and acid secretion by activating sst2 in dogs
    • Lloyd, K. C., Amirmoazzami, S., Friedik, E, Chew, P., and Walsh, J. H. (1997). Somatostatin inhibits gastrin release and acid secretion by activating sst2 in dogs. Am. J. Physiol. 272, G1481-G1488.
    • (1997) Am. J. Physiol. , vol.272
    • Lloyd, K.C.1    Amirmoazzami, S.2    Friedik, E.3    Chew, P.4    Walsh, J.H.5
  • 76
    • 84864774949 scopus 로고    scopus 로고
    • Postprandial inhibition of gastric ghrelin secretion by long-chain fatty acid (LCFA) through GPR 120 in isolated gastric ghrelin cells and mice
    • Lu, X., Zhao, X., Feng, J., Liou, A. P., Anthony, S., Pechhold, S., et al. (2012). Postprandial inhibition of gastric ghrelin secretion by long-chain fatty acid (LCFA) through GPR 120 in isolated gastric ghrelin cells and mice. Am. J. Physiol. Gastrointest. Liver Physiol. 303, G367-G376.
    • (2012) Am. J. Physiol. Gastrointest. Liver Physiol. , vol.303
    • Lu, X.1    Zhao, X.2    Feng, J.3    Liou, A.P.4    Anthony, S.5    Pechhold, S.6
  • 77
    • 1242296338 scopus 로고    scopus 로고
    • Expression and distribution of somatostatin receptor subtypes in the pancreatic islets of mice and rats
    • Ludvigsen, E., Olsson, R., Stridsberg, M., Janson, E. T., and Sandler, S. (2004). Expression and distribution of somatostatin receptor subtypes in the pancreatic islets of mice and rats. J. Histochem. Cytochem. 52,391-400.
    • (2004) J. Histochem. Cytochem. , vol.52 , pp. 391-400
    • Ludvigsen, E.1    Olsson, R.2    Stridsberg, M.3    Janson, E.T.4    Sandler, S.5
  • 79
    • 33745191222 scopus 로고    scopus 로고
    • Cortistatin mimics somatostatin by inducing a dual, dose-dependent stimulatory and inhibitory effect on growth hormone secretion in soma-totropes
    • Luque, R. M., Peinado, J. R., Gracia-Navarro, F., Broglio, F., Ghigo, E., Kineman, R. D., et al. (2006b). Cortistatin mimics somatostatin by inducing a dual, dose-dependent stimulatory and inhibitory effect on growth hormone secretion in soma-totropes. J. Mol. Endocrinol. 36, 547-556.
    • (2006) J. Mol. Endocrinol. , vol.36 , pp. 547-556
    • Luque, R.M.1    Peinado, J.R.2    Gracia-Navarro, F.3    Broglio, F.4    Ghigo, E.5    Kineman, R.D.6
  • 81
    • 0020516074 scopus 로고
    • Inhibitory effect of somatostatin-28 on pancreatic polypeptide, glucagon and insulin secretion in normal man
    • Marco, J., Correas, I., Zulueta, M. A., Vincent, E., Coy, D. H., Comaru-Schally, A. M., et al. (1983). Inhibitory effect of somatostatin-28 on pancreatic polypeptide, glucagon and insulin secretion in normal man. Horm. Metab. Res. 15, 363-366.
    • (1983) Horm. Metab. Res. , vol.15 , pp. 363-366
    • Marco, J.1    Correas, I.2    Zulueta, M.A.3    Vincent, E.4    Coy, D.H.5    Comaru-Schally, A.M.6
  • 82
    • 0343962642 scopus 로고    scopus 로고
    • Intracisternal injection of somatostatin receptor 5-preferring agonists induces a vagal cholinergic stimulation of gastric emptying in rats
    • Martinez, V., Rivier, J., Coy, D., and Taché, Y. (2000). Intracisternal injection of somatostatin receptor 5-preferring agonists induces a vagal cholinergic stimulation of gastric emptying in rats. J. Pharmacol. Exp. Ther. 293, 1099-1105.
    • (2000) J. Pharmacol. Exp. Ther. , vol.293 , pp. 1099-1105
    • Martinez, V.1    Rivier, J.2    Coy, D.3    Taché, Y.4
  • 83
    • 0022365002 scopus 로고
    • Evidence for corticotropin-releasing factor, neurotensin, and somatostatin in the neural pathway from the central nucleus of the amygdala to the parabrachial nucleus
    • Moga, M. M., and Gray, T. S. (1985). Evidence for corticotropin-releasing factor, neurotensin, and somatostatin in the neural pathway from the central nucleus of the amygdala to the parabrachial nucleus. J. Comp. Neu-rol. 241,275-284.
    • (1985) J. Comp. Neu-rol. , vol.241 , pp. 275-284
    • Moga, M.M.1    Gray, T.S.2
  • 84
    • 0027172417 scopus 로고
    • CRF in the paraventricular nucleus of the hypothalamus stimulates colonic motor activity in fasted rats
    • Mönnikes, H., Raybould, H. E., Schmidt, B., and Taché, Y. (1993). CRF in the paraventricular nucleus of the hypothalamus stimulates colonic motor activity in fasted rats. Peptides 14, 743-747.
    • (1993) Peptides , vol.14 , pp. 743-747
    • Mönnikes, H.1    Raybould, H.E.2    Schmidt, B.3    Taché, Y.4
  • 85
    • 0028322934 scopus 로고
    • Microinfusion of corti-cotropin releasing factor into the locus coeruleus/subcoeruleus nuclei stimulates colonic motor function in rats
    • Mönnikes, H., Schmidt, B. G., Tebbe, J., Bauer, C., and Taché, Y. (1994). Microinfusion of corti-cotropin releasing factor into the locus coeruleus/subcoeruleus nuclei stimulates colonic motor function in rats. Brain Res. 644, 101-108.
    • (1994) Brain Res , vol.644 , pp. 101-108
    • Mönnikes, H.1    Schmidt, B.G.2    Tebbe, J.3    Bauer, C.4    Taché, Y.5
  • 86
    • 77952109070 scopus 로고    scopus 로고
    • Electrophysiological effect of ghrelin and somatostatin on rat hypothala-mic arcuate neurons in vitro
    • Mori, K., Kim, J., and Sasaki, K. (2010). Electrophysiological effect of ghrelin and somatostatin on rat hypothala-mic arcuate neurons in vitro. Peptides 31, 1139-1145.
    • (2010) Peptides , vol.31 , pp. 1139-1145
    • Mori, K.1    Kim, J.2    Sasaki, K.3
  • 87
    • 0035072228 scopus 로고    scopus 로고
    • Binding of 125I-labeled ghrelin to membranes from human hypothalamus and pituitary gland
    • Muccioli, G., Papotti, M., Locatelli, V., Ghigo, E., and Deghenghi, R. (2001). Binding of 125I-labeled ghrelin to membranes from human hypothalamus and pituitary gland. J. Endocrinol. Invest. 24, RC7-RC9.
    • (2001) J. Endocrinol. Invest. , vol.24
    • Muccioli, G.1    Papotti, M.2    Locatelli, V.3    Ghigo, E.4    Deghenghi, R.5
  • 88
    • 20244366719 scopus 로고    scopus 로고
    • Ingested medium-chain fatty acids are directly utilized for the acyl modification of ghrelin
    • Nishi, Y., Hiejima, H., Hosoda, H., Kaiya, H., Mori, K., Fukue, Y., et al. (2005). Ingested medium-chain fatty acids are directly utilized for the acyl modification of ghrelin. Endocrinology 146, 2255-2264.
    • (2005) Endocrinology , vol.146 , pp. 2255-2264
    • Nishi, Y.1    Hiejima, H.2    Hosoda, H.3    Kaiya, H.4    Mori, K.5    Fukue, Y.6
  • 90
    • 33645420927 scopus 로고    scopus 로고
    • Differential BBB interactions of three ingestive peptides: obestatin, ghrelin, and adiponectin
    • Pan, W., Tu, H., and Kastin, A. J. (2006). Differential BBB interactions of three ingestive peptides: obestatin, ghrelin, and adiponectin. Peptides 27, 911-916.
    • (2006) Peptides , vol.27 , pp. 911-916
    • Pan, W.1    Tu, H.2    Kastin, A.J.3
  • 93
    • 82155166239 scopus 로고    scopus 로고
    • Novel therapeutic agents for the treatment of gastroenteropancre-atic neuroendocrine tumors
    • Pavel, M. E., and Wiedenmann, B. (2011). Novel therapeutic agents for the treatment of gastroenteropancre-atic neuroendocrine tumors. Horm. Metab. Res. 43, 844-853.
    • (2011) Horm. Metab. Res. , vol.43 , pp. 844-853
    • Pavel, M.E.1    Wiedenmann, B.2
  • 94
    • 0016679090 scopus 로고
    • The effect of somatostatin on release and insulinotropic action of gastric inhibitory polypeptide
    • Pederson, R. A., Dryburgh, J. R., and Brown, J. C. (1975). The effect of somatostatin on release and insulinotropic action of gastric inhibitory polypeptide. Can. J. Physiol. Pharmacol. 53, 1200-1205.
    • (1975) Can. J. Physiol. Pharmacol. , vol.53 , pp. 1200-1205
    • Pederson, R.A.1    Dryburgh, J.R.2    Brown, J.C.3
  • 96
    • 0037704513 scopus 로고    scopus 로고
    • Somatostatin receptor type 2 mediates bombesin-induced inhibition of gastric acid secretion in mice
    • Piqueras, L., Taché, Y., and Martinez, V. (2003). Somatostatin receptor type 2 mediates bombesin-induced inhibition of gastric acid secretion in mice. J. Physiol. 549, 889-901.
    • (2003) J. Physiol. , vol.549 , pp. 889-901
    • Piqueras, L.1    Taché, Y.2    Martinez, V.3
  • 97
    • 0018837330 scopus 로고
    • N-terminally extended somatostatin: the primary structure of somatostatin-28
    • Pradayrol, L., Jornvall, H., Mutt, V., and Ribet, A. (1980). N-terminally extended somatostatin: the primary structure of somatostatin-28. FEBS Lett. 109, 55-58.
    • (1980) FEBS Lett , vol.109 , pp. 55-58
    • Pradayrol, L.1    Jornvall, H.2    Mutt, V.3    Ribet, A.4
  • 98
    • 38549133093 scopus 로고    scopus 로고
    • Cortistatin-8, a synthetic cortistatin-derived ghrelin receptor ligand, does not modify the endocrine responses to acylated ghrelin or hexarelin in humans
    • Prodam, F., Benso, A., Gramaglia, E., Lucatello, B., Riganti, F., van der Lely, A. J., et al. (2008). Cortistatin-8, a synthetic cortistatin-derived ghrelin receptor ligand, does not modify the endocrine responses to acylated ghrelin or hexarelin in humans. Neu-ropeptides 42, 89-93.
    • (2008) Neu-ropeptides , vol.42 , pp. 89-93
    • Prodam, F.1    Benso, A.2    Gramaglia, E.3    Lucatello, B.4    Riganti, F.5    van der Lely, A.J.6
  • 99
    • 27744530393 scopus 로고    scopus 로고
    • Ghrelin expression in neuroendocrine tumours of the gastrointestinal tract with multiple endocrine neoplasia type 1
    • Raffel, A., Krausch, M., Cupisti, K., Gerharz, C. D., Eisenberger, C. F., and Knoefel, W. T. (2005). Ghrelin expression in neuroendocrine tumours of the gastrointestinal tract with multiple endocrine neoplasia type 1. Horm. Metab. Res. 37, 653-655.
    • (2005) Horm. Metab. Res. , vol.37 , pp. 653-655
    • Raffel, A.1    Krausch, M.2    Cupisti, K.3    Gerharz, C.D.4    Eisenberger, C.F.5    Knoefel, W.T.6
  • 100
    • 0021327318 scopus 로고
    • Inhibition of growth of pancreatic carcinomas in animal models by analogs of hypothalamic hormones
    • Redding, T.W., and Schally, A. V. (1984). Inhibition of growth of pancreatic carcinomas in animal models by analogs of hypothalamic hormones. Proc. Natl. Acad. Sci. U.S.A. 81, 248-252.
    • (1984) Proc. Natl. Acad. Sci. U. S. A. , vol.81 , pp. 248-252
    • Redding, T.W.1    Schally, A.V.2
  • 102
    • 0034677745 scopus 로고    scopus 로고
    • Subtypes of the somatostatin receptor assemble as functional homo and heterodimers
    • Rocheville, M., Lange, D. C., Kumar, U., Sasi, R., Patel, R. C., and Patel, Y C. (2000). Subtypes of the somatostatin receptor assemble as functional homo and heterodimers. J. Biol. Chem. 275, 7862-7869.
    • (2000) J. Biol. Chem. , vol.275 , pp. 7862-7869
    • Rocheville, M.1    Lange, D.C.2    Kumar, U.3    Sasi, R.4    Patel, R.C.5    Patel, Y.C.6
  • 103
    • 84867572078 scopus 로고    scopus 로고
    • The ghrelin O-acyltransferase-ghrelin system reduces TNF-alpha-induced apopto-sis and autophagy in human visceral adipocytes
    • Rodriguez, A., Gomez-Ambrosi, J., Catalan, V., Rotellar, F., Valenti, V., Silva, C., et al. (2012). The ghrelin O-acyltransferase-ghrelin system reduces TNF-alpha-induced apopto-sis and autophagy in human visceral adipocytes. Diabetologia 55, 3038- 3050.
    • (2012) Diabetologia , vol.55 , pp. 3038-3050
    • Rodriguez, A.1    Gomez-Ambrosi, J.2    Catalan, V.3    Rotellar, F.4    Valenti, V.5    Silva, C.6
  • 104
    • 0021711280 scopus 로고
    • Increase in neurotensin-like immunoreactivity in rat plasma after administration of calcium, bombesin and fat and its inhibition by somatostatin
    • Rokaeus, A. (1984). Increase in neurotensin-like immunoreactivity in rat plasma after administration of calcium, bombesin and fat and its inhibition by somatostatin. Acta Physiol. Scand. 122, 261-267.
    • (1984) Acta Physiol. Scand. , vol.122 , pp. 261-267
    • Rokaeus, A.1
  • 105
    • 34249652012 scopus 로고    scopus 로고
    • Spontaneous hypersensitivity in mesenteric afferent nerves of mice deficient in the sst2 subtype of somatostatin receptor
    • Rong, W., Winchester, W. J., and Grundy, D. (2007). Spontaneous hypersensitivity in mesenteric afferent nerves of mice deficient in the sst2 subtype of somatostatin receptor. J. Physiol. 581,779-786.
    • (2007) J. Physiol. , vol.581 , pp. 779-786
    • Rong, W.1    Winchester, W.J.2    Grundy, D.3
  • 107
    • 0038031634 scopus 로고    scopus 로고
    • Growth hormone secre-tagogue receptor expression in the cells of the stomach-projected afferent nerve in the rat nodose ganglion
    • Sakata, I., Yamazaki, M., Inoue, K., Hayashi, Y., Kangawa, K., and Sakai, T. (2003). Growth hormone secre-tagogue receptor expression in the cells of the stomach-projected afferent nerve in the rat nodose ganglion. Neurosci. Lett. 342,183-186.
    • (2003) Neurosci. Lett. , vol.342 , pp. 183-186
    • Sakata, I.1    Yamazaki, M.2    Inoue, K.3    Hayashi, Y.4    Kangawa, K.5    Sakai, T.6
  • 109
    • 65549152532 scopus 로고    scopus 로고
    • Anorexigenic and electrophysiological actions of novel ghrelin receptor (GHS-R1A) antagonists in rats
    • Salome, N., Haage, D., Perrissoud, D., Moulin, A., Demange, L., Egecioglu, E., et al. (2009). Anorexigenic and electrophysiological actions of novel ghrelin receptor (GHS-R1A) antagonists in rats. Eur. J. Pharmacol. 612, 167-173.
    • (2009) Eur. J. Pharmacol. , vol.612 , pp. 167-173
    • Salome, N.1    Haage, D.2    Perrissoud, D.3    Moulin, A.4    Demange, L.5    Egecioglu, E.6
  • 110
    • 17744399907 scopus 로고    scopus 로고
    • Bim-23244, a somatostatin receptor subtype 2 and 5-selective analog with enhanced efficacy in suppressing growth hormone (GH) from octreotide-resistant human GH-secreting adenomas
    • Saveanu, A., Gunz, G., Dufour, H., Caron, P., Fina, F., Ouafik, L., et al. (2001). Bim-23244, a somatostatin receptor subtype 2 and 5-selective analog with enhanced efficacy in suppressing growth hormone (GH) from octreotide-resistant human GH-secreting adenomas. J. Clin. Endocrinol. Metab. 86, 140-145.
    • (2001) J. Clin. Endocrinol. Metab. , vol.86 , pp. 140-145
    • Saveanu, A.1    Gunz, G.2    Dufour, H.3    Caron, P.4    Fina, F.5    Ouafik, L.6
  • 111
    • 0343776185 scopus 로고    scopus 로고
    • sst1 mRNA is the prominent somatostatin receptor mRNA in the rat gastrointestinal tract: reverse transcription polymerase chain reaction and in situ-hybridization study
    • Schafer, J., and Meyerhof, W. (1999). sst1 mRNA is the prominent somatostatin receptor mRNA in the rat gastrointestinal tract: reverse transcription polymerase chain reaction and in situ-hybridization study. Neu-ropeptides 33, 457-463.
    • (1999) Neu-ropeptides , vol.33 , pp. 457-463
    • Schafer, J.1    Meyerhof, W.2
  • 112
    • 0033737865 scopus 로고    scopus 로고
    • Localization of five somatostatin receptors in the rat central nervous system using subtype-specific antibodies
    • Schulz, S., Handel, M., Schreff, M., Schmidt, H., and Hollt, V. (2000). Localization of five somatostatin receptors in the rat central nervous system using subtype-specific antibodies. J. Physiol. Paris 94, 259-264.
    • (2000) J. Physiol. Paris , vol.94 , pp. 259-264
    • Schulz, S.1    Handel, M.2    Schreff, M.3    Schmidt, H.4    Hollt, V.5
  • 114
    • 5644225972 scopus 로고    scopus 로고
    • Both corticotropin-releasing factor receptor type 1 and type 2 are involved in stress-induced inhibition of food intake in rats
    • Sekino, A., Ohata, H., Mano-Otagiri, A., Arai, K., and Shibasaki, T. (2004). Both corticotropin-releasing factor receptor type 1 and type 2 are involved in stress-induced inhibition of food intake in rats. Psychopharma-cology (Berl.) 76, 30-38.
    • (2004) Psychopharma-cology (Berl.) , vol.76 , pp. 30-38
    • Sekino, A.1    Ohata, H.2    Mano-Otagiri, A.3    Arai, K.4    Shibasaki, T.5
  • 115
    • 36949027359 scopus 로고    scopus 로고
    • Growth hormone and somatostatin directly inhibit gastric ghrelin secretion An in vitro organ culture system
    • Seoane, L. M., Al-Massadi, O., Bar-reiro, F., Dieguez, C., and Casanueva, F. F. (2007). Growth hormone and somatostatin directly inhibit gastric ghrelin secretion. An in vitro organ culture system. J. Endocrinol. Invest. 30, RC22-RC25.
    • (2007) J. Endocrinol. Invest. , vol.30
    • Seoane, L.M.1    Al-Massadi, O.2    Bar-reiro, F.3    Dieguez, C.4    Casanueva, F.F.5
  • 116
    • 84857138764 scopus 로고    scopus 로고
    • Des-acyl ghrelin exhibits pro-anabolic and anti-catabolic effects on C2C12 myotubes exposed to cytokines and reduces burn-induced muscle proteolysis in rats
    • Sheriff, S., Kadeer, N., Joshi, R., Friend, L. A., James, J. H., and Balasubra-maniam, A. (2012). Des-acyl ghrelin exhibits pro-anabolic and anti-catabolic effects on C2C12 myotubes exposed to cytokines and reduces burn-induced muscle proteolysis in rats. Mol. Cell. Endocrinol. 351, 286-295.
    • (2012) Mol. Cell. Endocrinol. , vol.351 , pp. 286-295
    • Sheriff, S.1    Kadeer, N.2    Joshi, R.3    Friend, L.A.4    James, J.H.5    Balasubra-maniam, A.6
  • 118
    • 0031028364 scopus 로고    scopus 로고
    • Somatostatin receptor subtype specificity in human fet al pituitary cultures. Differential role of SSTR2 and SSTR5 for growth hormone, thyroid-stimulating hormone, and prolactin regulation
    • Shimon, I., Taylor, J. E., Dong, J. Z., Bitonte, R. A., Kim, S., Morgan, B., et al. (1997). Somatostatin receptor subtype specificity in human fet al pituitary cultures. Differential role of SSTR2 and SSTR5 for growth hormone, thyroid-stimulating hormone, and prolactin regulation. J. Clin. Invest. 99, 789-798.
    • (1997) J. Clin. Invest. , vol.99 , pp. 789-798
    • Shimon, I.1    Taylor, J.E.2    Dong, J.Z.3    Bitonte, R.A.4    Kim, S.5    Morgan, B.6
  • 119
    • 0025689520 scopus 로고
    • Somatostatin analog, SMS 201-995, inhibits pancreatic exocrine secretion and release of secretin and cholecystokinin in rats
    • Shiratori, K., Watanabe, S., and Takeuchi, T. (1991). Somatostatin analog, SMS 201-995, inhibits pancreatic exocrine secretion and release of secretin and cholecystokinin in rats. Pancreas 6, 23-30.
    • (1991) Pancreas , vol.6 , pp. 23-30
    • Shiratori, K.1    Watanabe, S.2    Takeuchi, T.3
  • 120
    • 84867573081 scopus 로고    scopus 로고
    • Pharmacological characterization of the ghrelin receptor mediating its inhibitory action on inflammatory pain in rats
    • Sibilia, V., Pagani, F., Mrak, E., Dieci, E., Tulipano, G., and Ferrucci, F. (2012). Pharmacological characterization of the ghrelin receptor mediating its inhibitory action on inflammatory pain in rats. Amino Acids 43, 1751-1759.
    • (2012) Amino Acids , vol.43 , pp. 1751-1759
    • Sibilia, V.1    Pagani, F.2    Mrak, E.3    Dieci, E.4    Tulipano, G.5    Ferrucci, F.6
  • 122
    • 21344474829 scopus 로고    scopus 로고
    • Regulation of ghrelin secretion by somatostatin analogs in rats
    • Silva, A. P., Bethmann, K., Raulf, F., andSchmid,H.A. (2005). Regulation of ghrelin secretion by somatostatin analogs in rats. Eur. J. Endocrinol. 152, 887-894.
    • (2005) Eur. J. Endocrinol. , vol.152 , pp. 887-894
    • Silva, A.P.1    Bethmann, K.2    Raulf, F.3    Schmid, H.A.4
  • 123
    • 0032786990 scopus 로고    scopus 로고
    • Dual effects of somatostatin analog octreotide on gastric emptying during and after intragastric fill
    • Smedh, U., Kaplan, J. M., Bjork-strand, E., and Uvnas-Moberg, K. (1999). Dual effects of somatostatin analog octreotide on gastric emptying during and after intragastric fill. Am. J. Physiol. 277, R1291-R1296.
    • (1999) Am. J. Physiol. , vol.277
    • Smedh, U.1    Kaplan, J.M.2    Bjork-strand, E.3    Uvnas-Moberg, K.4
  • 124
    • 37349041658 scopus 로고    scopus 로고
    • Expression and localisation of somatostatin receptor subtypes sst1-sst5 in areas of the rat medulla oblongata involved in autonomic regulation
    • Spary, E. J., Maqbool, A., and Batten, T. F. (2008). Expression and localisation of somatostatin receptor subtypes sst1-sst5 in areas of the rat medulla oblongata involved in autonomic regulation. J. Chem. Neuroanat. 35, 49-66.
    • (2008) J. Chem. Neuroanat. , vol.35 , pp. 49-66
    • Spary, E.J.1    Maqbool, A.2    Batten, T.F.3
  • 125
    • 0033818629 scopus 로고    scopus 로고
    • Cortistatin: a member of the somatostatin neuropeptide family with distinct physiological functions
    • Spier, A. D., and de Lecea, L. (2000). Cortistatin: a member of the somatostatin neuropeptide family with distinct physiological functions. Brain Res. Brain Res. Rev. 33,228-241.
    • (2000) Brain Res. Brain Res. Rev , vol.33 , pp. 228-241
    • Spier, A.D.1    de Lecea, L.2
  • 126
    • 77956021196 scopus 로고    scopus 로고
    • Central injection of the stable somatostatin analog ODT8-SST induces a somatostatin2 receptor-mediated orexigenic effect: role of neuropeptide Y and opioid signaling pathways in rats
    • Stengel, A., Coskun, T., Goebel, M., Wang, L., Craft, L., Alsina-Fernandez, J., et al. (2010a). Central injection of the stable somatostatin analog ODT8-SST induces a somatostatin2 receptor-mediated orexigenic effect: role of neuropeptide Y and opioid signaling pathways in rats. Endocrinology 151,4224-4235.
    • (2010) Endocrinology , vol.151 , pp. 4224-4235
    • Stengel, A.1    Coskun, T.2    Goebel, M.3    Wang, L.4    Craft, L.5    Alsina-Fernandez, J.6
  • 127
    • 78049457734 scopus 로고    scopus 로고
    • Cold ambient temperature reverses abdominal surgery-induced delayed gastric emptying, and decreased plasma ghrelin levels in rats
    • Stengel, A., Goebel, M., Luckey, A., Yuan, P. Q., Wang, L., and Taché, Y. (2010b). Cold ambient temperature reverses abdominal surgery-induced delayed gastric emptying, and decreased plasma ghrelin levels in rats. Peptides 31, 2229-2235.
    • (2010) Peptides , vol.31 , pp. 2229-2235
    • Stengel, A.1    Goebel, M.2    Luckey, A.3    Yuan, P.Q.4    Wang, L.5    Taché, Y.6
  • 128
    • 78149261367 scopus 로고    scopus 로고
    • Activation of brain somato-statin(2) receptors stimulates feeding in mice: analysis of food intake microstructure
    • Stengel, A., Goebel, M., Wang, L., Riv-ier, J., Kobelt, P., Mönnikes, H., et al. (2010c). Activation of brain somato-statin(2) receptors stimulates feeding in mice: analysis of food intake microstructure. Physiol. Behav. 101, 614-622.
    • (2010) Physiol. Behav. , vol.101 , pp. 614-622
    • Stengel, A.1    Goebel, M.2    Wang, L.3    Riv-ier, J.4    Kobelt, P.5    Mönnikes, H.6
  • 129
    • 77956175010 scopus 로고    scopus 로고
    • Selective central activation of somatostatin2 receptor increases food intake, grooming behavior and rectal temperature in rats
    • Stengel, A., Goebel, M., Wang, L., Riv-ier, J., Kobelt, P., Mönnikes, H., et al. (2010d). Selective central activation of somatostatin2 receptor increases food intake, grooming behavior and rectal temperature in rats. J. Physiol. Pharmacol. 61, 399-407.
    • (2010) J. Physiol. Pharmacol. , vol.61 , pp. 399-407
    • Stengel, A.1    Goebel, M.2    Wang, L.3    Riv-ier, J.4    Kobelt, P.5    Mönnikes, H.6
  • 130
    • 74149087844 scopus 로고    scopus 로고
    • Ghrelin, des-acyl ghrelin, and nesfatin-1 in gastric X/A-like cells: role as regulators of food intake and body weight
    • Stengel, A., Goebel, M., Wang, L., and Taché, Y (2010e). Ghrelin, des-acyl ghrelin, and nesfatin-1 in gastric X/A-like cells: role as regulators of food intake and body weight. Peptides 31, 357-369.
    • (2010) Peptides , vol.31 , pp. 357-369
    • Stengel, A.1    Goebel, M.2    Wang, L.3    Taché, Y.4
  • 131
    • 75049085779 scopus 로고    scopus 로고
    • Differential distribution of ghrelin-O-acyltransferase (GOAT) immunoreactive cells in the mouse and rat gastric oxyntic mucosa
    • Stengel, A., Goebel, M., Wang, L., Taché, Y., Sachs, G., and Lambrecht, N. W (2010f). Differential distribution of ghrelin-O-acyltransferase (GOAT) immunoreactive cells in the mouse and rat gastric oxyntic mucosa. Biochem. Biophys. Res. Commun. 392,67-71.
    • (2010) Biochem. Biophys. Res. Commun. , vol.392 , pp. 67-71
    • Stengel, A.1    Goebel, M.2    Wang, L.3    Taché, Y.4    Sachs, G.5    Lambrecht, N.W.6
  • 132
    • 79955899476 scopus 로고    scopus 로고
    • Central somatostatin receptor 1 activation reverses acute stress-related alterations of gastric, and colonic motor function in mice
    • Stengel, A., Goebel-Stengel, M., Wang, L., Larauche, M., Rivier, J., and Taché, Y (2011a). Central somatostatin receptor 1 activation reverses acute stress-related alterations of gastric, and colonic motor function in mice. Neurogastroenterol. Motil. 23, e223-e236.
    • (2011) Neurogastroenterol. Motil. , vol.23
    • Stengel, A.1    Goebel-Stengel, M.2    Wang, L.3    Larauche, M.4    Rivier, J.5    Taché, Y.6
  • 133
    • 79959324854 scopus 로고    scopus 로고
    • Central administration of pan-somatostatin agonist ODT8-SST prevents abdominal surgery-induced inhibition of circulating ghrelin, food intake and gastric emptying in rats
    • Stengel, A., Goebel-Stengel, M., Wang, L., Luckey, A., Hu, E., Rivier, J., et al. (2011b). Central administration of pan-somatostatin agonist ODT8-SST prevents abdominal surgery-induced inhibition of circulating ghrelin, food intake and gastric emptying in rats. Neurogastroenterol. Motil. 23, e294-e308.
    • (2011) Neurogastroenterol. Motil. , vol.23
    • Stengel, A.1    Goebel-Stengel, M.2    Wang, L.3    Luckey, A.4    Hu, E.5    Rivier, J.6
  • 134
    • 79960005949 scopus 로고    scopus 로고
    • Abdominal surgery inhibits circulating acyl ghrelin, and ghrelin-O-acyltransferase levels in rats: role of the somatostatin receptor subtype 2
    • Stengel, A., Goebel-Stengel, M., Wang, L., Shaikh, A., Lambrecht, N. W., Rivier, J. E., et al. (2011c). Abdominal surgery inhibits circulating acyl ghrelin, and ghrelin-O-acyltransferase levels in rats: role of the somatostatin receptor subtype 2. Am. J. Physiol. Gastrointest. Liver Physiol. 301, G239-G248.
    • (2011) Am. J. Physiol. Gastrointest. Liver Physiol. , vol.301
    • Stengel, A.1    Goebel-Stengel, M.2    Wang, L.3    Shaikh, A.4    Lambrecht, N.W.5    Rivier, J.E.6
  • 135
    • 70350266819 scopus 로고    scopus 로고
    • The RAPID method for blood processing yields new insight in plasma concentrations and molecular forms of circulating gut peptides
    • Stengel, A., Keire, D., Goebel, M., Evile-vitch, L., Wiggins, B., Taché, Y., et al. (2009). The RAPID method for blood processing yields new insight in plasma concentrations and molecular forms of circulating gut peptides. Endocrinology 150, 5113-5118.
    • (2009) Endocrinology , vol.150 , pp. 5113-5118
    • Stengel, A.1    Keire, D.2    Goebel, M.3    Evile-vitch, L.4    Wiggins, B.5    Taché, Y.6
  • 136
    • 0030759999 scopus 로고    scopus 로고
    • Somatostatin 2A receptor is expressed by enteric neurons, and by interstitial cells of Cajal and enterochromaffin-like cells of the gastrointestinal tract
    • Sternini, C., Wong, H., Wu, S. V., de Giorgio, R., Yang, M., Reeve, J. Jr., et al. (1997). Somatostatin 2A receptor is expressed by enteric neurons, and by interstitial cells of Cajal and enterochromaffin-like cells of the gastrointestinal tract. J. Comp. Neu-rol. 386, 396-408.
    • (1997) J. Comp. Neu-rol. , vol.386 , pp. 396-408
    • Sternini, C.1    Wong, H.2    Wu, S.V.3    de Giorgio, R.4    Yang, M.5    Reeve Jr, J.6
  • 138
    • 0034465470 scopus 로고    scopus 로고
    • Somatostatin inhibits insulin and glucagon secretion via two receptors subtypes: an in vitro study of pancreatic islets from somatostatin receptor 2 knockout mice
    • Strowski, M. Z., Parmar, R. M., Blake, A. D., and Schaeffer, J. M. (2000). Somatostatin inhibits insulin and glucagon secretion via two receptors subtypes: an in vitro study of pancreatic islets from somatostatin receptor 2 knockout mice. Endocrinology 141, 111-117.
    • (2000) Endocrinology , vol.141 , pp. 111-117
    • Strowski, M.Z.1    Parmar, R.M.2    Blake, A.D.3    Schaeffer, J.M.4
  • 139
    • 0242580169 scopus 로고    scopus 로고
    • Deletion of ghrelin impairs neither growth nor appetite
    • Sun, Y., Ahmed, S., and Smith, R. G. (2003). Deletion of ghrelin impairs neither growth nor appetite. Mol. Cell. Biol. 23, 7973-7981.
    • (2003) Mol. Cell. Biol. , vol.23 , pp. 7973-7981
    • Sun, Y.1    Ahmed, S.2    Smith, R.G.3
  • 140
    • 1842480284 scopus 로고    scopus 로고
    • Ghrelin stimulation of growth hormone release and appetite is mediated through the growth hormone secretagogue receptor
    • Sun, Y., Wang, P., Zheng, H., and Smith, R. G. (2004). Ghrelin stimulation of growth hormone release and appetite is mediated through the growth hormone secretagogue receptor. Proc. Natl. Acad. Sci. U.S.A. 101, 4679-4684.
    • (2004) Proc. Natl. Acad. Sci. U. S. A. , vol.101 , pp. 4679-4684
    • Sun, Y.1    Wang, P.2    Zheng, H.3    Smith, R.G.4
  • 141
    • 84865068238 scopus 로고    scopus 로고
    • The gut hormones in appetite regulation
    • Suzuki, K., Jayasena, C. N., and Bloom, S. R. (2011). The gut hormones in appetite regulation. J. Obes. 2011, 528401.
    • (2011) J. Obes. , vol.2011 , pp. 528401
    • Suzuki, K.1    Jayasena, C.N.2    Bloom, S.R.3
  • 142
    • 6044243758 scopus 로고    scopus 로고
    • Epidemiology of neuroendocrine tumours
    • Taal, B. G., and Visser, O. (2004). Epidemiology of neuroendocrine tumours. Neuroendocrinology 80 (Suppl. 1), 3-7.
    • (2004) Neuroendocrinology , vol.80 , Issue.SUPPL. 1 , pp. 3-7
    • Taal, B.G.1    Visser, O.2
  • 143
    • 33846000959 scopus 로고    scopus 로고
    • Corticotropin-releasing factor receptors and stress-related alterations of gut motor function
    • Taché, Y., and Bonaz, B. (2007). Corticotropin-releasing factor receptors and stress-related alterations of gut motor function. J. Clin. Invest. 117,33-40.
    • (2007) J. Clin. Invest. , vol.117 , pp. 33-40
    • Taché, Y.1    Bonaz, B.2
  • 144
    • 4644274876 scopus 로고    scopus 로고
    • Central administration of ghrelin and agouti-related protein (83-132) increases food intake and decreases spontaneous locomotor activity in rats
    • Tang-Christensen, M., Vrang, N., Ort-mann, S., Bidlingmaier, M., Horvath, T. L., and Tschöp, M. (2004). Central administration of ghrelin and agouti-related protein (83-132) increases food intake and decreases spontaneous locomotor activity in rats. Endocrinology 45, 4645-4652.
    • (2004) Endocrinology , vol.45 , pp. 4645-4652
    • Tang-Christensen, M.1    Vrang, N.2    Ort-mann, S.3    Bidlingmaier, M.4    Horvath, T.L.5    Tschöp, M.6
  • 145
    • 0018728454 scopus 로고
    • Species difference in GI motor response to somatostatin
    • Tansy, M. F., Martin, J. S., Landin, W. E., and Kendall, F. M. (1979). Species difference in GI motor response to somatostatin. J. Pharm. Sci. 68,1107- 1113.
    • (1979) J. Pharm. Sci. , vol.68 , pp. 1107-1113
    • Tansy, M.F.1    Martin, J.S.2    Landin, W.E.3    Kendall, F.M.4
  • 146
    • 13844255029 scopus 로고    scopus 로고
    • Excitatory stimulation of neurons in the arcuate nucleus initiates central CRF-dependent stimulation of colonic propulsion in rats
    • Tebbe, J. J., Pasat, I. R., Mönnikes, H., Ritter, M., Kobelt, P., and Schafer, M. K. (2005). Excitatory stimulation of neurons in the arcuate nucleus initiates central CRF-dependent stimulation of colonic propulsion in rats. Brain Res. 1036,130-138.
    • (2005) Brain Res , vol.1036 , pp. 130-138
    • Tebbe, J.J.1    Pasat, I.R.2    Mönnikes, H.3    Ritter, M.4    Kobelt, P.5    Schafer, M.K.6
  • 147
    • 0029617807 scopus 로고
    • Embryonic and postnatal mRNA distribution of five somatostatin receptor subtypes in the rat brain
    • Thoss, V. S., Perez, J., Duc, D., and Hoyer, D. (1995). Embryonic and postnatal mRNA distribution of five somatostatin receptor subtypes in the rat brain. Neuropharmacology 34, 1673-1688.
    • (1995) Neuropharmacology , vol.34 , pp. 1673-1688
    • Thoss, V.S.1    Perez, J.2    Duc, D.3    Hoyer, D.4
  • 148
    • 0026726011 scopus 로고
    • Effect of various neurotransmitters and neuropeptides on the release of corticotropin-releasing hormone from the rat cortex in vitro
    • Tizabi, Y., and Calogero, A. E. (1992). Effect of various neurotransmitters and neuropeptides on the release of corticotropin-releasing hormone from the rat cortex in vitro. Synapse 10,341-348.
    • (1992) Synapse , vol.10 , pp. 341-348
    • Tizabi, Y.1    Calogero, A.E.2
  • 149
    • 0034809159 scopus 로고    scopus 로고
    • Upregulation of ghrelin expression in the stomach upon fasting, insulin-induced hypo-glycemia, and leptin administration
    • Toshinai, K., Mondal, M. S., Nakazato, M., Date, Y., Murakami, N., Kojima, M., et al. (2001). Upregulation of ghrelin expression in the stomach upon fasting, insulin-induced hypo-glycemia, and leptin administration. Biochem. Biophys. Res. Commun. 281, 1220-1225.
    • (2001) Biochem. Biophys. Res. Commun. , vol.281 , pp. 1220-1225
    • Toshinai, K.1    Mondal, M.S.2    Nakazato, M.3    Date, Y.4    Murakami, N.5    Kojima, M.6
  • 150
    • 84859419532 scopus 로고    scopus 로고
    • Cortistatin modulates the expression and release of corticotrophin releasing hormone in rat brain Comparison with somatostatin and octreotide
    • Tringali, G., Greco, M. C., Lisi, L., Pozzoli, G., and Navarra, P. (2012). Cortistatin modulates the expression and release of corticotrophin releasing hormone in rat brain. Comparison with somatostatin and octreotide. Peptides 34, 353-359.
    • (2012) Peptides , vol.34 , pp. 353-359
    • Tringali, G.1    Greco, M.C.2    Lisi, L.3    Pozzoli, G.4    Navarra, P.5
  • 151
    • 0034687376 scopus 로고    scopus 로고
    • Ghrelin induces adiposity in rodents
    • Tschöp, M., Smiley, D. L., and Heiman, M. L. (2000). Ghrelin induces adiposity in rodents. Nature 407, 908-913.
    • (2000) Nature , vol.407 , pp. 908-913
    • Tschöp, M.1    Smiley, D.L.2    Heiman, M.L.3
  • 155
    • 0021984694 scopus 로고
    • Somatostatin receptors: distribution in rat central nervous system and human frontal cortex
    • Uhl, G. R., Tran, V., Snyder, S. H., and Martin, J. B. (1985). Somatostatin receptors: distribution in rat central nervous system and human frontal cortex. J. Comp. Neurol. 240, 288-304.
    • (1985) J. Comp. Neurol. , vol.240 , pp. 288-304
    • Uhl, G.R.1    Tran, V.2    Snyder, S.H.3    Martin, J.B.4
  • 157
    • 33744953964 scopus 로고    scopus 로고
    • Ghrelin potentiates growth hormone secretion driven by putative somatostatin withdrawal and resists inhibition by human corticotropin-releasing hormone
    • Veldhuis, J. D., Iranmanesh, A., Mielke, K., Miles, J. M., Carpenter, P. C., and Bowers, C. Y. (2006). Ghrelin potentiates growth hormone secretion driven by putative somatostatin withdrawal and resists inhibition by human corticotropin-releasing hormone. J. Clin. Endocrinol. Metab. 91, 2441-2446.
    • (2006) J. Clin. Endocrinol. Metab. , vol.91 , pp. 2441-2446
    • Veldhuis, J.D.1    Iranmanesh, A.2    Mielke, K.3    Miles, J.M.4    Carpenter, P.C.5    Bowers, C.Y.6
  • 159
    • 0033792363 scopus 로고    scopus 로고
    • Involvement of sst2 somatostatin receptor in locomotor, exploratory activity and emotional reactivity in mice
    • Viollet, C., Vaillend, C., Videau, C., Bluet-Pajot, M. T., Ungerer, A., L'Heritier, A., et al. (2000). Involvement of sst2 somatostatin receptor in locomotor, exploratory activity and emotional reactivity in mice. Eur. J. Neurosci. 12,3761-3770.
    • (2000) Eur. J. Neurosci. , vol.12 , pp. 3761-3770
    • Viollet, C.1    Vaillend, C.2    Videau, C.3    Bluet-Pajot, M.T.4    Ungerer, A.5    L'Heritier, A.6
  • 160
    • 0036959760 scopus 로고    scopus 로고
    • Expression of ghrelin and of the GH secretagogue receptor by pancreatic islet cells and related endocrine tumors
    • Volante, M., Allia, E., Gugliotta, P., Funaro, A., Broglio, F., Deghenghi, R., et al. (2002). Expression of ghrelin and of the GH secretagogue receptor by pancreatic islet cells and related endocrine tumors. J. Clin. Endocrinol. Metab. 87, 1300-1308.
    • (2002) J. Clin. Endocrinol. Metab. , vol.87 , pp. 1300-1308
    • Volante, M.1    Allia, E.2    Gugliotta, P.3    Funaro, A.4    Broglio, F.5    Deghenghi, R.6
  • 161
    • 84874245105 scopus 로고
    • Physiology of the Gastrointestinal Tract, ed L. R. Johnson (New York: Raven Press)
    • Walsh, J. (1994). "Somatostatin," in Physiology of the Gastrointestinal Tract, ed. L. R. Johnson (New York: Raven Press), 31-48.
    • (1994) Somatostatin , pp. 31-48
    • Walsh, J.1
  • 162
    • 80052837215 scopus 로고    scopus 로고
    • Comparison of CRF-immunoreactive neurons distribution in mouse and rat brains and selective induction of Fos in rat hypothalamic CRF neurons by abdominal surgery
    • Wang, L., Goebel-Stengel, M., Stengel, A., Wu, S. V., Ohning, G., and Taché, Y. (2011). Comparison of CRF-immunoreactive neurons distribution in mouse and rat brains and selective induction of Fos in rat hypothalamic CRF neurons by abdominal surgery. Brain Res. 1415, 34-46.
    • (2011) Brain Res , vol.1415 , pp. 34-46
    • Wang, L.1    Goebel-Stengel, M.2    Stengel, A.3    Wu, S.V.4    Ohning, G.5    Taché, Y.6
  • 163
    • 0033711116 scopus 로고    scopus 로고
    • The novel hypothalamic peptide ghrelin stimulates food intake and growth hormone secretion
    • Wren, A. M., Small, C. J., Ward, H. L., Murphy, K. G., Dakin, C. L., Taheri, S., et al. (2000). The novel hypothalamic peptide ghrelin stimulates food intake and growth hormone secretion. Endocrinology 141, 4325-4328.
    • (2000) Endocrinology , vol.141 , pp. 4325-4328
    • Wren, A.M.1    Small, C.J.2    Ward, H.L.3    Murphy, K.G.4    Dakin, C.L.5    Taheri, S.6
  • 164
    • 34447554007 scopus 로고    scopus 로고
    • RT-PCR and immunocytochem-istry studies support the presence of somatostatin, cortistatin and somatostatin receptor subtypes in rat Kupffer cells
    • Xidakis, C., Mastrodimou, N., Notas, G., Renieri, E., Kolios, G., Kouroumalis, E., et al. (2007). RT-PCR and immunocytochem-istry studies support the presence of somatostatin, cortistatin and somatostatin receptor subtypes in rat Kupffer cells. Regul. Pept. 143, 76-82.
    • (2007) Regul. Pept. , vol.143 , pp. 76-82
    • Xidakis, C.1    Mastrodimou, N.2    Notas, G.3    Renieri, E.4    Kolios, G.5    Kouroumalis, E.6
  • 165
    • 67651177691 scopus 로고    scopus 로고
    • Gastric mammalian target of rapamycin signaling regulates ghrelin production and food intake
    • Xu, G., Li, Y., An, W., Li, S., Guan, Y., Wang, N., et al. (2009). Gastric mammalian target of rapamycin signaling regulates ghrelin production and food intake. Endocrinology 150, 3637-3644.
    • (2009) Endocrinology , vol.150 , pp. 3637-3644
    • Xu, G.1    Li, Y.2    An, W.3    Li, S.4    Guan, Y.5    Wang, N.6
  • 167
    • 0036141444 scopus 로고    scopus 로고
    • Regulational effect of ghrelin on growth hormone secretion from perfused rat anterior pituitary cells
    • Yamazaki, M., Nakamura, K., Kobayashi, H., Matsubara, M., Hayashi, Y., Kangawa, K., et al. (2002). Regulational effect of ghrelin on growth hormone secretion from perfused rat anterior pituitary cells. J. Neuro endocrinol. 14, 156-162.
    • (2002) J. Neuro endocrinol. , vol.14 , pp. 156-162
    • Yamazaki, M.1    Nakamura, K.2    Kobayashi, H.3    Matsubara, M.4    Hayashi, Y.5    Kangawa, K.6
  • 168
    • 0025367377 scopus 로고
    • Somatostatin monoclonal antibody immunoneu-tralization increases gastrin and gastric acid secretion in urethane-anesthetized rats
    • Yang, H., Wong, H., Wu, V., Walsh, J. H., and Taché, Y. (1990). Somatostatin monoclonal antibody immunoneu-tralization increases gastrin and gastric acid secretion in urethane-anesthetized rats. Gastroenterology 99,659-665.
    • (1990) Gastroenterology , vol.99 , pp. 659-665
    • Yang, H.1    Wong, H.2    Wu, V.3    Walsh, J.H.4    Taché, Y.5
  • 169
    • 38849090670 scopus 로고    scopus 로고
    • Identification of the acyl-transferase that octanoylates ghrelin, an appetite-stimulating peptide hormone
    • Yang, J., Brown, M. S., Liang, G., Grishin, N. V., and Goldstein, J. L. (2008). Identification of the acyl-transferase that octanoylates ghrelin, an appetite-stimulating peptide hormone. Cell 132, 387-396.
    • (2008) Cell , vol.132 , pp. 387-396
    • Yang, J.1    Brown, M.S.2    Liang, G.3    Grishin, N.V.4    Goldstein, J.L.5
  • 170
    • 31044451759 scopus 로고    scopus 로고
    • Mice lacking ghrelin receptors resist the development of diet-induced obesity
    • Zigman, J. M., Nakano, Y., Coppari, R., Balthasar, N., Marcus, J. N., Lee, C. E., et al. (2005). Mice lacking ghrelin receptors resist the development of diet-induced obesity. J. Clin. Invest. 115,3564-3572.
    • (2005) J. Clin. Invest. , vol.115 , pp. 3564-3572
    • Zigman, J.M.1    Nakano, Y.2    Coppari, R.3    Balthasar, N.4    Marcus, J.N.5    Lee, C.E.6


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