-
1
-
-
0023875503
-
The complete amino acid sequence of human complement factor H
-
Ripoche, J., Day, A. J., Harris, T. J., and Sim, R. B. (1988) The complete amino acid sequence of human complement factor H Biochem. J. 249, 593-602
-
(1988)
Biochem. J.
, vol.249
, pp. 593-602
-
-
Ripoche, J.1
Day, A.J.2
Harris, T.J.3
Sim, R.B.4
-
2
-
-
36849044745
-
Translational Mini-Review Series on Complement Factor H: Structural and functional correlations for factor H
-
Schmidt, C. Q., Herbert, A. P., Hocking, H. G., Uhrin, D., and Barlow, P. N. (2008) Translational Mini-Review Series on Complement Factor H: Structural and functional correlations for factor H Clin. Exp. Immunol. 151, 14-24
-
(2008)
Clin. Exp. Immunol.
, vol.151
, pp. 14-24
-
-
Schmidt, C.Q.1
Herbert, A.P.2
Hocking, H.G.3
Uhrin, D.4
Barlow, P.N.5
-
3
-
-
0017704496
-
Human complement C3b inactivator: Isolation, characterization, and demonstration of an absolute requirement for the serum protein β1H for cleavage of C3b and C4b in solution
-
Pangburn, M. K., Schreiber, R. D., and Muller-Eberhard, H. J. (1977) Human complement C3b inactivator: Isolation, characterization, and demonstration of an absolute requirement for the serum protein β1H for cleavage of C3b and C4b in solution J. Exp. Med. 146, 257-270
-
(1977)
J. Exp. Med.
, vol.146
, pp. 257-270
-
-
Pangburn, M.K.1
Schreiber, R.D.2
Muller-Eberhard, H.J.3
-
4
-
-
77953266787
-
The amplification loop of the complement pathways
-
Lachmann, P. J. (2009) The amplification loop of the complement pathways Adv. Immunol. 104, 115-149
-
(2009)
Adv. Immunol.
, vol.104
, pp. 115-149
-
-
Lachmann, P.J.1
-
5
-
-
0035849176
-
Complement. Second of two parts
-
Walport, M. J. (2001) Complement. Second of two parts N. Engl. J. Med. 344, 1140-1144
-
(2001)
N. Engl. J. Med.
, vol.344
, pp. 1140-1144
-
-
Walport, M.J.1
-
6
-
-
0035810399
-
Complement. First of two parts
-
Walport, M. J. (2001) Complement. First of two parts N. Engl. J. Med. 344, 1058-1066
-
(2001)
N. Engl. J. Med.
, vol.344
, pp. 1058-1066
-
-
Walport, M.J.1
-
7
-
-
77955883153
-
Complement: A key system for immune surveillance and homeostasis
-
Ricklin, D., Hajishengallis, G., Yang, K., and Lambris, J. D. (2010) Complement: A key system for immune surveillance and homeostasis Nat. Immunol. 11, 785-797
-
(2010)
Nat. Immunol.
, vol.11
, pp. 785-797
-
-
Ricklin, D.1
Hajishengallis, G.2
Yang, K.3
Lambris, J.D.4
-
8
-
-
0025314311
-
Discrimination between activators and nonactivators of the alternative pathway of complement: Regulation via a sialic acid/polyanion binding site on factor H
-
Meri, S. and Pangburn, M. K. (1990) Discrimination between activators and nonactivators of the alternative pathway of complement: Regulation via a sialic acid/polyanion binding site on factor H Proc. Natl. Acad. Sci. U.S.A. 87, 3982-3986
-
(1990)
Proc. Natl. Acad. Sci. U.S.A.
, vol.87
, pp. 3982-3986
-
-
Meri, S.1
Pangburn, M.K.2
-
9
-
-
0030590494
-
Analysis of the recognition mechanism of the alternative pathway of complement by monoclonal anti-factor H antibodies: Evidence for multiple interactions between H and surface bound C3b
-
Jokiranta, T. S., Zipfel, P. F., Hakulinen, J., Kuhn, S., Pangburn, M. K., Tamerius, J. D., and Meri, S. (1996) Analysis of the recognition mechanism of the alternative pathway of complement by monoclonal anti-factor H antibodies: Evidence for multiple interactions between H and surface bound C3b FEBS Lett. 393, 297-302
-
(1996)
FEBS Lett.
, vol.393
, pp. 297-302
-
-
Jokiranta, T.S.1
Zipfel, P.F.2
Hakulinen, J.3
Kuhn, S.4
Pangburn, M.K.5
Tamerius, J.D.6
Meri, S.7
-
10
-
-
33750336175
-
Critical role of the C-terminal domains of factor H in regulating complement activation at cell surfaces
-
Ferreira, V. P., Herbert, A. P., Hocking, H. G., Barlow, P. N., and Pangburn, M. K. (2006) Critical role of the C-terminal domains of factor H in regulating complement activation at cell surfaces J. Immunol. 177, 6308-6316
-
(2006)
J. Immunol.
, vol.177
, pp. 6308-6316
-
-
Ferreira, V.P.1
Herbert, A.P.2
Hocking, H.G.3
Barlow, P.N.4
Pangburn, M.K.5
-
11
-
-
0030058570
-
Control of the complement system
-
Liszewski, M. K., Farries, T. C., Lublin, D. M., Rooney, I. A., and Atkinson, J. P. (1996) Control of the complement system Adv. Immunol. 61, 201-283
-
(1996)
Adv. Immunol.
, vol.61
, pp. 201-283
-
-
Liszewski, M.K.1
Farries, T.C.2
Lublin, D.M.3
Rooney, I.A.4
Atkinson, J.P.5
-
12
-
-
0035008505
-
Structure and flexibility of the multiple domain proteins that regulate complement activation
-
Kirkitadze, M. D. and Barlow, P. N. (2001) Structure and flexibility of the multiple domain proteins that regulate complement activation Immunol. Rev. 180, 146-161
-
(2001)
Immunol. Rev.
, vol.180
, pp. 146-161
-
-
Kirkitadze, M.D.1
Barlow, P.N.2
-
13
-
-
36849084660
-
Translational mini-review series on complement factor H: Genetics and disease associations of human complement factor H
-
de Cordoba, S. R. and de Jorge, E. G. (2008) Translational mini-review series on complement factor H: Genetics and disease associations of human complement factor H Clin. Exp. Immunol. 151, 1-13
-
(2008)
Clin. Exp. Immunol.
, vol.151
, pp. 1-13
-
-
De Cordoba, S.R.1
De Jorge, E.G.2
-
14
-
-
0033927532
-
Complement factor H gene mutation associated with autosomal recessive atypical hemolytic uremic syndrome
-
Buddles, M. R., Donne, R. L., Richards, A., Goodship, J., and Goodship, T. H. (2000) Complement factor H gene mutation associated with autosomal recessive atypical hemolytic uremic syndrome Am. J. Hum. Genet. 66, 1721-1722
-
(2000)
Am. J. Hum. Genet.
, vol.66
, pp. 1721-1722
-
-
Buddles, M.R.1
Donne, R.L.2
Richards, A.3
Goodship, J.4
Goodship, T.H.5
-
15
-
-
33847237272
-
The interactive Factor H-atypical hemolytic uremic syndrome mutation database and website: Update and integration of membrane cofactor protein and Factor i mutations with structural models
-
Saunders, R. E., Abarrategui-Garrido, C., Fremeaux-Bacchi, V., Goicoechea de Jorge, E., Goodship, T. H., Lopez Trascasa, M., Noris, M., Ponce Castro, I. M., Remuzzi, G., Rodriguez de Cordoba, S., Sanchez-Corral, P., Skerka, C., Zipfel, P. F., and Perkins, S. J. (2007) The interactive Factor H-atypical hemolytic uremic syndrome mutation database and website: Update and integration of membrane cofactor protein and Factor I mutations with structural models Hum. Mutat. 28, 222-234
-
(2007)
Hum. Mutat.
, vol.28
, pp. 222-234
-
-
Saunders, R.E.1
Abarrategui-Garrido, C.2
Fremeaux-Bacchi, V.3
Goicoechea De Jorge, E.4
Goodship, T.H.5
Lopez Trascasa, M.6
Noris, M.7
Ponce Castro, I.M.8
Remuzzi, G.9
Rodriguez De Cordoba, S.10
Sanchez-Corral, P.11
Skerka, C.12
Zipfel, P.F.13
Perkins, S.J.14
-
16
-
-
78449293078
-
Genetics and complement in atypical HUS
-
Kavanagh, D. and Goodship, T. (2010) Genetics and complement in atypical HUS Pediatr. Nephrol. 25, 2431-2442
-
(2010)
Pediatr. Nephrol.
, vol.25
, pp. 2431-2442
-
-
Kavanagh, D.1
Goodship, T.2
-
17
-
-
0029060511
-
Identification of complement regulatory domains in human factor H
-
Gordon, D. L., Kaufman, R. M., Blackmore, T. K., Kwong, J., and Lublin, D. M. (1995) Identification of complement regulatory domains in human factor H J. Immunol. 155, 348-356
-
(1995)
J. Immunol.
, vol.155
, pp. 348-356
-
-
Gordon, D.L.1
Kaufman, R.M.2
Blackmore, T.K.3
Kwong, J.4
Lublin, D.M.5
-
18
-
-
0035128326
-
Factor H mutations in hemolytic uremic syndrome cluster in exons 18-20, a domain important for host cell recognition
-
Richards, A., Buddles, M. R., Donne, R. L., Kaplan, B. S., Kirk, E., Venning, M. C., Tielemans, C. L., Goodship, J. A., and Goodship, T. H. (2001) Factor H mutations in hemolytic uremic syndrome cluster in exons 18-20, a domain important for host cell recognition Am. J. Hum. Genet. 68, 485-490
-
(2001)
Am. J. Hum. Genet.
, vol.68
, pp. 485-490
-
-
Richards, A.1
Buddles, M.R.2
Donne, R.L.3
Kaplan, B.S.4
Kirk, E.5
Venning, M.C.6
Tielemans, C.L.7
Goodship, J.A.8
Goodship, T.H.9
-
19
-
-
0036838535
-
Cutting edge: Localization of the host recognition functions of complement factor H at the carboxyl-terminal: Implications for hemolytic uremic syndrome
-
Pangburn, M. K. (2002) Cutting edge: Localization of the host recognition functions of complement factor H at the carboxyl-terminal: Implications for hemolytic uremic syndrome J. Immunol. 169, 4702-4706
-
(2002)
J. Immunol.
, vol.169
, pp. 4702-4706
-
-
Pangburn, M.K.1
-
20
-
-
37349123478
-
Implications of the progressive self-association of wild-type human factor H for complement regulation and disease
-
Nan, R., Gor, J., and Perkins, S. J. (2008) Implications of the progressive self-association of wild-type human factor H for complement regulation and disease J. Mol. Biol. 375, 891-900
-
(2008)
J. Mol. Biol.
, vol.375
, pp. 891-900
-
-
Nan, R.1
Gor, J.2
Perkins, S.J.3
-
21
-
-
60549088365
-
Polyanion-induced self-association of complement factor H
-
Pangburn, M. K., Rawal, N., Cortes, C., Alam, M. N., Ferreira, V. P., and Atkinson, M. A. (2009) Polyanion-induced self-association of complement factor H J. Immunol. 182, 1061-1068
-
(2009)
J. Immunol.
, vol.182
, pp. 1061-1068
-
-
Pangburn, M.K.1
Rawal, N.2
Cortes, C.3
Alam, M.N.4
Ferreira, V.P.5
Atkinson, M.A.6
-
22
-
-
53149104792
-
A new map of glycosaminoglycan and C3b binding sites on factor H
-
Schmidt, C. Q., Herbert, A. P., Kavanagh, D., Gandy, C., Fenton, C. J., Blaum, B. S., Lyon, M., Uhrin, D., and Barlow, P. N. (2008) A new map of glycosaminoglycan and C3b binding sites on factor H J. Immunol. 181, 2610-2619
-
(2008)
J. Immunol.
, vol.181
, pp. 2610-2619
-
-
Schmidt, C.Q.1
Herbert, A.P.2
Kavanagh, D.3
Gandy, C.4
Fenton, C.J.5
Blaum, B.S.6
Lyon, M.7
Uhrin, D.8
Barlow, P.N.9
-
23
-
-
79953772478
-
Structural basis for engagement by complement factor H of C3b on a self surface
-
Morgan, H. P., Schmidt, C. Q., Guariento, M., Blaum, B. S., Gillespie, D., Herbert, A. P., Kavanagh, D., Mertens, H. D., Svergun, D. I., Johansson, C. M., Uhrin, D., Barlow, P. N., and Hannan, J. P. (2011) Structural basis for engagement by complement factor H of C3b on a self surface Nat. Struct. Mol. Biol. 18, 463-470
-
(2011)
Nat. Struct. Mol. Biol.
, vol.18
, pp. 463-470
-
-
Morgan, H.P.1
Schmidt, C.Q.2
Guariento, M.3
Blaum, B.S.4
Gillespie, D.5
Herbert, A.P.6
Kavanagh, D.7
Mertens, H.D.8
Svergun, D.I.9
Johansson, C.M.10
Uhrin, D.11
Barlow, P.N.12
Hannan, J.P.13
-
24
-
-
67449119124
-
The binding of factor H to a complex of physiological polyanions and C3b on cells is impaired in atypical hemolytic uremic syndrome
-
Ferreira, V. P., Herbert, A. P., Cortes, C., McKee, K. A., Blaum, B. S., Esswein, S. T., Uhrin, D., Barlow, P. N., Pangburn, M. K., and Kavanagh, D. (2009) The binding of factor H to a complex of physiological polyanions and C3b on cells is impaired in atypical hemolytic uremic syndrome J. Immunol. 182, 7009-7018
-
(2009)
J. Immunol.
, vol.182
, pp. 7009-7018
-
-
Ferreira, V.P.1
Herbert, A.P.2
Cortes, C.3
McKee, K.A.4
Blaum, B.S.5
Esswein, S.T.6
Uhrin, D.7
Barlow, P.N.8
Pangburn, M.K.9
Kavanagh, D.10
-
25
-
-
0038068044
-
A common site within factor H SCR 7 responsible for binding heparin, C-reactive protein and streptococcal M protein
-
Giannakis, E., Jokiranta, T. S., Male, D. A., Ranganathan, S., Ormsby, R. J., Fischetti, V. A., Mold, C., and Gordon, D. L. (2003) A common site within factor H SCR 7 responsible for binding heparin, C-reactive protein and streptococcal M protein Eur. J. Immunol. 33, 962-969
-
(2003)
Eur. J. Immunol.
, vol.33
, pp. 962-969
-
-
Giannakis, E.1
Jokiranta, T.S.2
Male, D.A.3
Ranganathan, S.4
Ormsby, R.J.5
Fischetti, V.A.6
Mold, C.7
Gordon, D.L.8
-
26
-
-
34547102526
-
Structure shows that a glycosaminoglycan and protein recognition site in factor H is perturbed by age-related macular degeneration-linked single nucleotide polymorphism
-
Herbert, A. P., Deakin, J. A., Schmidt, C. Q., Blaum, B. S., Egan, C., Ferreira, V. P., Pangburn, M. K., Lyon, M., Uhrin, D., and Barlow, P. N. (2007) Structure shows that a glycosaminoglycan and protein recognition site in factor H is perturbed by age-related macular degeneration-linked single nucleotide polymorphism J. Biol. Chem. 282, 18960-18968
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 18960-18968
-
-
Herbert, A.P.1
Deakin, J.A.2
Schmidt, C.Q.3
Blaum, B.S.4
Egan, C.5
Ferreira, V.P.6
Pangburn, M.K.7
Lyon, M.8
Uhrin, D.9
Barlow, P.N.10
-
27
-
-
34948910047
-
Structural basis for complement factor H-linked age-related macular degeneration
-
Prosser, B. E., Johnson, S., Roversi, P., Herbert, A. P., Blaum, B. S., Tyrrell, J., Jowitt, T. A., Clark, S. J., Tarelli, E., Uhrin, D., Barlow, P. N., Sim, R. B., Day, A. J., and Lea, S. M. (2007) Structural basis for complement factor H-linked age-related macular degeneration J. Exp. Med. 204, 2277-2283
-
(2007)
J. Exp. Med.
, vol.204
, pp. 2277-2283
-
-
Prosser, B.E.1
Johnson, S.2
Roversi, P.3
Herbert, A.P.4
Blaum, B.S.5
Tyrrell, J.6
Jowitt, T.A.7
Clark, S.J.8
Tarelli, E.9
Uhrin, D.10
Barlow, P.N.11
Sim, R.B.12
Day, A.J.13
Lea, S.M.14
-
28
-
-
21044453724
-
A common haplotype in the complement regulatory gene factor H (HF1/CFH) predisposes individuals to age-related macular degeneration
-
Hageman, G. S., Anderson, D. H., Johnson, L. V., Hancox, L. S., Taiber, A. J., Hardisty, L. I., Hageman, J. L., Stockman, H. A., Borchardt, J. D., Gehrs, K. M., Smith, R. J., Silvestri, G., Russell, S. R., Klaver, C. C., Barbazetto, I., Chang, S., Yannuzzi, L. A., Barile, G. R., Merriam, J. C., Smith, R. T., Olsh, A. K., Bergeron, J., Zernant, J., Merriam, J. E., Gold, B., Dean, M., and Allikmets, R. (2005) A common haplotype in the complement regulatory gene factor H (HF1/CFH) predisposes individuals to age-related macular degeneration Proc. Natl. Acad. Sci. U.S.A. 102, 7227-7232
-
(2005)
Proc. Natl. Acad. Sci. U.S.A.
, vol.102
, pp. 7227-7232
-
-
Hageman, G.S.1
Anderson, D.H.2
Johnson, L.V.3
Hancox, L.S.4
Taiber, A.J.5
Hardisty, L.I.6
Hageman, J.L.7
Stockman, H.A.8
Borchardt, J.D.9
Gehrs, K.M.10
Smith, R.J.11
Silvestri, G.12
Russell, S.R.13
Klaver, C.C.14
Barbazetto, I.15
Chang, S.16
Yannuzzi, L.A.17
Barile, G.R.18
Merriam, J.C.19
Smith, R.T.20
Olsh, A.K.21
Bergeron, J.22
Zernant, J.23
Merriam, J.E.24
Gold, B.25
Dean, M.26
Allikmets, R.27
more..
-
29
-
-
17244379811
-
Complement factor H polymorphism and age-related macular degeneration
-
Edwards, A. O., Ritter, R., Abel, K. J., Manning, A., Panhuysen, C., and Farrer, L. A. (2005) Complement factor H polymorphism and age-related macular degeneration Science 308, 421-424
-
(2005)
Science
, vol.308
, pp. 421-424
-
-
Edwards, A.O.1
Ritter, R.2
Abel, K.J.3
Manning, A.4
Panhuysen, C.5
Farrer, L.A.6
-
30
-
-
20244388812
-
Complement factor H variant increases the risk of age-related macular degeneration
-
Haines, J. L., Hauser, M. A., Schmidt, S., Scott, W. K., Olson, L. M., Gallins, P., Spencer, K. L., Kwan, S. Y., Noureddine, M., Gilbert, J. R., Schnetz-Boutaud, N., Agarwal, A., Postel, E. A., and Pericak-Vance, M. A. (2005) Complement factor H variant increases the risk of age-related macular degeneration Science 308, 419-421
-
(2005)
Science
, vol.308
, pp. 419-421
-
-
Haines, J.L.1
Hauser, M.A.2
Schmidt, S.3
Scott, W.K.4
Olson, L.M.5
Gallins, P.6
Spencer, K.L.7
Kwan, S.Y.8
Noureddine, M.9
Gilbert, J.R.10
Schnetz-Boutaud, N.11
Agarwal, A.12
Postel, E.A.13
Pericak-Vance, M.A.14
-
31
-
-
20244380171
-
Complement factor H polymorphism in age-related macular degeneration
-
Klein, R. J., Zeiss, C., Chew, E. Y., Tsai, J. Y., Sackler, R. S., Haynes, C., Henning, A. K., SanGiovanni, J. P., Mane, S. M., Mayne, S. T., Bracken, M. B., Ferris, F. L., Ott, J., Barnstable, C., and Hoh, J. (2005) Complement factor H polymorphism in age-related macular degeneration Science 308, 385-389
-
(2005)
Science
, vol.308
, pp. 385-389
-
-
Klein, R.J.1
Zeiss, C.2
Chew, E.Y.3
Tsai, J.Y.4
Sackler, R.S.5
Haynes, C.6
Henning, A.K.7
Sangiovanni, J.P.8
Mane, S.M.9
Mayne, S.T.10
Bracken, M.B.11
Ferris, F.L.12
Ott, J.13
Barnstable, C.14
Hoh, J.15
-
32
-
-
70450225410
-
The central portion of factor H (modules 10-15) is compact and contains a structurally deviant CCP module
-
Schmidt, C. Q., Herbert, A. P., Mertens, H. D., Guariento, M., Soares, D. C., Uhrin, D., Rowe, A. J., Svergun, D. I., and Barlow, P. N. (2010) The central portion of factor H (modules 10-15) is compact and contains a structurally deviant CCP module J. Mol. Biol. 395, 105-122
-
(2010)
J. Mol. Biol.
, vol.395
, pp. 105-122
-
-
Schmidt, C.Q.1
Herbert, A.P.2
Mertens, H.D.3
Guariento, M.4
Soares, D.C.5
Uhrin, D.6
Rowe, A.J.7
Svergun, D.I.8
Barlow, P.N.9
-
33
-
-
47749126514
-
Factor H family proteins and human diseases
-
Jozsi, M. and Zipfel, P. F. (2008) Factor H family proteins and human diseases Trends Immunol. 29, 380-387
-
(2008)
Trends Immunol.
, vol.29
, pp. 380-387
-
-
Jozsi, M.1
Zipfel, P.F.2
-
34
-
-
34047200899
-
Deletion of complement factor H-related genes CFHR1 and CFHR3 is associated with atypical hemolytic uremic syndrome
-
Zipfel, P. F., Edey, M., Heinen, S., Jozsi, M., Richter, H., Misselwitz, J., Hoppe, B., Routledge, D., Strain, L., Hughes, A. E., Goodship, J. A., Licht, C., Goodship, T. H., and Skerka, C. (2007) Deletion of complement factor H-related genes CFHR1 and CFHR3 is associated with atypical hemolytic uremic syndrome PLoS Genet. 3, e41
-
(2007)
PLoS Genet.
, vol.3
, pp. 41
-
-
Zipfel, P.F.1
Edey, M.2
Heinen, S.3
Jozsi, M.4
Richter, H.5
Misselwitz, J.6
Hoppe, B.7
Routledge, D.8
Strain, L.9
Hughes, A.E.10
Goodship, J.A.11
Licht, C.12
Goodship, T.H.13
Skerka, C.14
-
35
-
-
33746655453
-
De novo gene conversion in the RCA gene cluster (1q32) causes mutations in complement factor H associated with atypical hemolytic uremic syndrome
-
Heinen, S., Sanchez-Corral, P., Jackson, M. S., Strain, L., Goodship, J. A., Kemp, E. J., Skerka, C., Jokiranta, T. S., Meyers, K., Wagner, E., Robitaille, P., Esparza-Gordillo, J., Rodriguez de Cordoba, S., Zipfel, P. F., and Goodship, T. H. (2006) De novo gene conversion in the RCA gene cluster (1q32) causes mutations in complement factor H associated with atypical hemolytic uremic syndrome Hum. Mutat. 27, 292-293
-
(2006)
Hum. Mutat.
, vol.27
, pp. 292-293
-
-
Heinen, S.1
Sanchez-Corral, P.2
Jackson, M.S.3
Strain, L.4
Goodship, J.A.5
Kemp, E.J.6
Skerka, C.7
Jokiranta, T.S.8
Meyers, K.9
Wagner, E.10
Robitaille, P.11
Esparza-Gordillo, J.12
Rodriguez De Cordoba, S.13
Zipfel, P.F.14
Goodship, T.H.15
-
36
-
-
33646164894
-
Structure of complement factor H carboxyl-terminus reveals molecular basis of atypical haemolytic uremic syndrome
-
Jokiranta, T. S., Jaakola, V. P., Lehtinen, M. J., Parepalo, M., Meri, S., and Goldman, A. (2006) Structure of complement factor H carboxyl-terminus reveals molecular basis of atypical haemolytic uremic syndrome EMBO J. 25, 1784-1794
-
(2006)
EMBO J.
, vol.25
, pp. 1784-1794
-
-
Jokiranta, T.S.1
Jaakola, V.P.2
Lehtinen, M.J.3
Parepalo, M.4
Meri, S.5
Goldman, A.6
-
37
-
-
33746655453
-
De novo gene conversion in the RCA gene cluster (1q32) causes mutations in complement factor H associated with atypical hemolytic uremic syndrome
-
Heinen, S., Sanchez-Corral, P., Jackson, M. S., Strain, L., Goodship, J. A., Kemp, E. J., Skerka, C., Jokiranta, T. S., Meyers, K., Wagner, E., Robitaille, P., Esparza-Gordillo, J., Rodriguez de Cordoba, S., Zipfel, P. F., and Goodship, T. H. (2006) De novo gene conversion in the RCA gene cluster (1q32) causes mutations in complement factor H associated with atypical hemolytic uremic syndrome Hum. Mutat. 27, 292-293
-
(2006)
Hum. Mutat.
, vol.27
, pp. 292-293
-
-
Heinen, S.1
Sanchez-Corral, P.2
Jackson, M.S.3
Strain, L.4
Goodship, J.A.5
Kemp, E.J.6
Skerka, C.7
Jokiranta, T.S.8
Meyers, K.9
Wagner, E.10
Robitaille, P.11
Esparza-Gordillo, J.12
Rodriguez De Cordoba, S.13
Zipfel, P.F.14
Goodship, T.H.15
-
38
-
-
70349441306
-
Factor H-related protein 1 (CFHR-1) inhibits complement C5 convertase activity and terminal complex formation
-
Heinen, S., Hartmann, A., Lauer, N., Wiehl, U., Dahse, H. M., Schirmer, S., Gropp, K., Enghardt, T., Wallich, R., Halbich, S., Mihlan, M., Schlotzer-Schrehardt, U., Zipfel, P. F., and Skerka, C. (2009) Factor H-related protein 1 (CFHR-1) inhibits complement C5 convertase activity and terminal complex formation Blood 114, 2439-2447
-
(2009)
Blood
, vol.114
, pp. 2439-2447
-
-
Heinen, S.1
Hartmann, A.2
Lauer, N.3
Wiehl, U.4
Dahse, H.M.5
Schirmer, S.6
Gropp, K.7
Enghardt, T.8
Wallich, R.9
Halbich, S.10
Mihlan, M.11
Schlotzer-Schrehardt, U.12
Zipfel, P.F.13
Skerka, C.14
-
39
-
-
78549235728
-
Delineation of the complement receptor type 2-C3d complex by site-directed mutagenesis and molecular docking
-
Shaw, C. D., Storek, M. J., Young, K. A., Kovacs, J. M., Thurman, J. M., Holers, V. M., and Hannan, J. P. (2010) Delineation of the complement receptor type 2-C3d complex by site-directed mutagenesis and molecular docking J. Mol. Biol. 404, 697-710
-
(2010)
J. Mol. Biol.
, vol.404
, pp. 697-710
-
-
Shaw, C.D.1
Storek, M.J.2
Young, K.A.3
Kovacs, J.M.4
Thurman, J.M.5
Holers, V.M.6
Hannan, J.P.7
-
40
-
-
37549034278
-
Isolating the Epstein-Barr virus gp350/220 binding site on complement receptor type 2 (CR2/CD21)
-
Young, K. A., Chen, X. S., Holers, V. M., and Hannan, J. P. (2007) Isolating the Epstein-Barr virus gp350/220 binding site on complement receptor type 2 (CR2/CD21) J. Biol. Chem. 282, 36614-36625
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 36614-36625
-
-
Young, K.A.1
Chen, X.S.2
Holers, V.M.3
Hannan, J.P.4
-
41
-
-
34247243536
-
The decay accelerating factor mutation I197V found in hemolytic uraemic syndrome does not impair complement regulation
-
Kavanagh, D., Burgess, R., Spitzer, D., Richards, A., Diaz-Torres, M. L., Goodship, J. A., Hourcade, D. E., Atkinson, J. P., and Goodship, T. H. (2007) The decay accelerating factor mutation I197V found in hemolytic uraemic syndrome does not impair complement regulation Mol. Immunol. 44, 3162-3167
-
(2007)
Mol. Immunol.
, vol.44
, pp. 3162-3167
-
-
Kavanagh, D.1
Burgess, R.2
Spitzer, D.3
Richards, A.4
Diaz-Torres, M.L.5
Goodship, J.A.6
Hourcade, D.E.7
Atkinson, J.P.8
Goodship, T.H.9
-
42
-
-
33745202838
-
Disease-associated sequence variations congregate in a polyanion recognition patch on human factor H revealed in three-dimensional structure
-
Herbert, A. P., Uhrin, D., Lyon, M., Pangburn, M. K., and Barlow, P. N. (2006) Disease-associated sequence variations congregate in a polyanion recognition patch on human factor H revealed in three-dimensional structure J. Biol. Chem. 281, 16512-16520
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 16512-16520
-
-
Herbert, A.P.1
Uhrin, D.2
Lyon, M.3
Pangburn, M.K.4
Barlow, P.N.5
-
43
-
-
19444382397
-
The CCPN data model for NMR spectroscopy: Development of a software pipeline
-
Vranken, W. F., Boucher, W., Stevens, T. J., Fogh, R. H., Pajon, A., Llinas, M., Ulrich, E. L., Markley, J. L., Ionides, J., and Laue, E. D. (2005) The CCPN data model for NMR spectroscopy: Development of a software pipeline Proteins 59, 687-696
-
(2005)
Proteins
, vol.59
, pp. 687-696
-
-
Vranken, W.F.1
Boucher, W.2
Stevens, T.J.3
Fogh, R.H.4
Pajon, A.5
Llinas, M.6
Ulrich, E.L.7
Markley, J.L.8
Ionides, J.9
Laue, E.D.10
-
44
-
-
0003076963
-
Recent changes to the MOSFLM package for processing film and image plate data
-
Daresbury Laboratory, Warrington, U.K.
-
Leslie, A. G. W. (1992) Recent changes to the MOSFLM package for processing film and image plate data. Joint CCP4 + ESF-EAMCB Newsletter on Protein Crystallography, Daresbury Laboratory, Warrington, U.K.
-
(1992)
Joint CCP4 + ESF-EAMCB Newsletter on Protein Crystallography
-
-
Leslie, A.G.W.1
-
45
-
-
33644875355
-
Scaling and assessment of data quality
-
Evans, P. (2006) Scaling and assessment of data quality Acta Crystallogr. D62, 72-82
-
(2006)
Acta Crystallogr.
, vol.62
, pp. 72-82
-
-
Evans, P.1
-
46
-
-
34447508216
-
Phaser crystallographic software
-
McCoy, A. J., Grosse-Kunstleve, R. W., Adams, P. D., Winn, M. D., Storoni, L. C., and Read, R. J. (2007) Phaser crystallographic software J. Appl. Crystallogr. 40, 658-674
-
(2007)
J. Appl. Crystallogr.
, vol.40
, pp. 658-674
-
-
McCoy, A.J.1
Grosse-Kunstleve, R.W.2
Adams, P.D.3
Winn, M.D.4
Storoni, L.C.5
Read, R.J.6
-
47
-
-
14244272868
-
PHENIX: Building new software for automated crystallographic structure determination
-
Adams, P. D., Grosse-Kunstleve, R. W., Hung, L. W., Ioerger, T. R., McCoy, A. J., Moriarty, N. W., Read, R. J., Sacchettini, J. C., Sauter, N. K., and Terwilliger, T. C. (2002) PHENIX: Building new software for automated crystallographic structure determination Acta Crystallogr. D58, 1948-1954
-
(2002)
Acta Crystallogr.
, vol.58
, pp. 1948-1954
-
-
Adams, P.D.1
Grosse-Kunstleve, R.W.2
Hung, L.W.3
Ioerger, T.R.4
McCoy, A.J.5
Moriarty, N.W.6
Read, R.J.7
Sacchettini, J.C.8
Sauter, N.K.9
Terwilliger, T.C.10
-
48
-
-
13244281317
-
Coot: Model-building tools for molecular graphics
-
Emsley, P. and Cowtan, K. (2004) Coot: Model-building tools for molecular graphics Acta Crystallogr. D60, 2126-2132
-
(2004)
Acta Crystallogr.
, vol.60
, pp. 2126-2132
-
-
Emsley, P.1
Cowtan, K.2
-
49
-
-
33646260450
-
Optimal description of a protein structure in terms of multiple groups undergoing TLS motion
-
Painter, J. and Merritt, E. A. (2006) Optimal description of a protein structure in terms of multiple groups undergoing TLS motion Acta Crystallogr. D62, 439-450
-
(2006)
Acta Crystallogr.
, vol.62
, pp. 439-450
-
-
Painter, J.1
Merritt, E.A.2
-
50
-
-
34547592557
-
MolProbity: All-atom contacts and structure validation for proteins and nucleic acids
-
Davis, I. W., Leaver-Fay, A., Chen, V. B., Block, J. N., Kapral, G. J., Wang, X., Murray, L. W., Arendall, W. B., III, Snoeyink, J., Richardson, J. S., and Richardson, D. C. (2007) MolProbity: All-atom contacts and structure validation for proteins and nucleic acids Nucleic Acids Res. 35, W375-W383
-
(2007)
Nucleic Acids Res.
, vol.35
-
-
Davis, I.W.1
Leaver-Fay, A.2
Chen, V.B.3
Block, J.N.4
Kapral, G.J.5
Wang, X.6
Murray, L.W.7
Arendall III, W.B.8
Snoeyink, J.9
Richardson, J.S.10
Richardson, D.C.11
-
51
-
-
4143121255
-
Evaluation of fluorescence-based thermal shift assays for hit identification in drug discovery
-
Lo, M. C., Aulabaugh, A., Jin, G., Cowling, R., Bard, J., Malamas, M., and Ellestad, G. (2004) Evaluation of fluorescence-based thermal shift assays for hit identification in drug discovery Anal. Biochem. 332, 153-159
-
(2004)
Anal. Biochem.
, vol.332
, pp. 153-159
-
-
Lo, M.C.1
Aulabaugh, A.2
Jin, G.3
Cowling, R.4
Bard, J.5
Malamas, M.6
Ellestad, G.7
-
52
-
-
0029783312
-
Energetics of cyclodextrin-induced dissociation of insulin
-
Lovatt, M., Cooper, A., and Camilleri, P. (1996) Energetics of cyclodextrin-induced dissociation of insulin Eur. Biophys. J. 24, 354-357
-
(1996)
Eur. Biophys. J.
, vol.24
, pp. 354-357
-
-
Lovatt, M.1
Cooper, A.2
Camilleri, P.3
-
53
-
-
79952612300
-
Dual interaction of factor H with C3d and glycosaminoglycans in host-nonhost discrimination by complement
-
Kajander, T., Lehtinen, M. J., Hyvarinen, S., Bhattacharjee, A., Leung, E., Isenman, D. E., Meri, S., Goldman, A., and Jokiranta, T. S. (2011) Dual interaction of factor H with C3d and glycosaminoglycans in host-nonhost discrimination by complement Proc. Natl. Acad. Sci. U.S.A. 108, 2897-2902
-
(2011)
Proc. Natl. Acad. Sci. U.S.A.
, vol.108
, pp. 2897-2902
-
-
Kajander, T.1
Lehtinen, M.J.2
Hyvarinen, S.3
Bhattacharjee, A.4
Leung, E.5
Isenman, D.E.6
Meri, S.7
Goldman, A.8
Jokiranta, T.S.9
-
54
-
-
0033153280
-
Independently melting modules and highly structured intermodular junctions within complement receptor type 1
-
Kirkitadze, M. D., Krych, M., Uhrin, D., Dryden, D. T., Smith, B. O., Cooper, A., Wang, X., Hauhart, R., Atkinson, J. P., and Barlow, P. N. (1999) Independently melting modules and highly structured intermodular junctions within complement receptor type 1 Biochemistry 38, 7019-7031
-
(1999)
Biochemistry
, vol.38
, pp. 7019-7031
-
-
Kirkitadze, M.D.1
Krych, M.2
Uhrin, D.3
Dryden, D.T.4
Smith, B.O.5
Cooper, A.6
Wang, X.7
Hauhart, R.8
Atkinson, J.P.9
Barlow, P.N.10
-
55
-
-
56949096518
-
Uncontrolled zinc- and copper-induced oligomerisation of the human complement regulator factor H and its possible implications for function and disease
-
Nan, R., Gor, J., Lengyel, I., and Perkins, S. J. (2008) Uncontrolled zinc- and copper-induced oligomerisation of the human complement regulator factor H and its possible implications for function and disease J. Mol. Biol. 384, 1341-1352
-
(2008)
J. Mol. Biol.
, vol.384
, pp. 1341-1352
-
-
Nan, R.1
Gor, J.2
Lengyel, I.3
Perkins, S.J.4
-
56
-
-
77958035712
-
Protein flexibility and conformational entropy in ligand design targeting the carbohydrate recognition domain of galectin-3
-
Diehl, C., Engstrom, O., Delaine, T., Hakansson, M., Genheden, S., Modig, K., Leffler, H., Ryde, U., Nilsson, U. J., and Akke, M. (2010) Protein flexibility and conformational entropy in ligand design targeting the carbohydrate recognition domain of galectin-3 J. Am. Chem. Soc. 132, 14577-14589
-
(2010)
J. Am. Chem. Soc.
, vol.132
, pp. 14577-14589
-
-
Diehl, C.1
Engstrom, O.2
Delaine, T.3
Hakansson, M.4
Genheden, S.5
Modig, K.6
Leffler, H.7
Ryde, U.8
Nilsson, U.J.9
Akke, M.10
-
57
-
-
44049086967
-
Structure of the N-terminal Region of Complement Factor H and Conformational Implications of Disease-linked Sequence Variations
-
Hocking, H. G., Herbert, A. P., Kavanagh, D., Soares, D. C., Ferreira, V. P., Pangburn, M. K., Uhrin, D., and Barlow, P. N. (2008) Structure of the N-terminal Region of Complement Factor H and Conformational Implications of Disease-linked Sequence Variations J. Biol. Chem. 283, 9475-9487
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 9475-9487
-
-
Hocking, H.G.1
Herbert, A.P.2
Kavanagh, D.3
Soares, D.C.4
Ferreira, V.P.5
Pangburn, M.K.6
Uhrin, D.7
Barlow, P.N.8
-
58
-
-
67649230210
-
Structure of complement fragment C3b-factor H and implications for host protection by complement regulators
-
Wu, J., Wu, Y. Q., Ricklin, D., Janssen, B. J., Lambris, J. D., and Gros, P. (2009) Structure of complement fragment C3b-factor H and implications for host protection by complement regulators Nat. Immunol. 10, 728-733
-
(2009)
Nat. Immunol.
, vol.10
, pp. 728-733
-
-
Wu, J.1
Wu, Y.Q.2
Ricklin, D.3
Janssen, B.J.4
Lambris, J.D.5
Gros, P.6
-
59
-
-
79953190798
-
Disease-associated N-terminal complement factor H mutations perturb cofactor and decay-accelerating activities
-
Pechtl, I. C., Kavanagh, D., McIntosh, N., Harris, C. L., and Barlow, P. N. (2011) Disease-associated N-terminal complement factor H mutations perturb cofactor and decay-accelerating activities J. Biol. Chem. 286, 11082-11090
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 11082-11090
-
-
Pechtl, I.C.1
Kavanagh, D.2
McIntosh, N.3
Harris, C.L.4
Barlow, P.N.5
-
60
-
-
69449090499
-
The disease-protective complement factor H allotypic variant Ile62 shows increased binding affinity for C3b and enhanced cofactor activity
-
Tortajada, A., Montes, T., Martinez-Barricarte, R., Morgan, B. P., Harris, C. L., and de Cordoba, S. R. (2009) The disease-protective complement factor H allotypic variant Ile62 shows increased binding affinity for C3b and enhanced cofactor activity Hum. Mol. Genet. 18, 3452-3461
-
(2009)
Hum. Mol. Genet.
, vol.18
, pp. 3452-3461
-
-
Tortajada, A.1
Montes, T.2
Martinez-Barricarte, R.3
Morgan, B.P.4
Harris, C.L.5
De Cordoba, S.R.6
-
61
-
-
80052272216
-
Factor H-related protein 1 neutralizes anti-factor H autoantibodies in
-
Strobel, S., Abarrategui-Garrido, C., Fariza-Requejo, E., Seeberger, H., Sanchez-Corral, P., and Jozsi, M. (2011) Factor H-related protein 1 neutralizes anti-factor H autoantibodies in Kidney Int. 80, 397-404
-
(2011)
Kidney Int.
, vol.80
, pp. 397-404
-
-
Strobel, S.1
Abarrategui-Garrido, C.2
Fariza-Requejo, E.3
Seeberger, H.4
Sanchez-Corral, P.5
Jozsi, M.6
|