Understanding the molecular basis of age-related macular degeneration and how the identification of new mechanisms may aid the development of novel therapies

Expert Review of Ophthalmology

Volumn 6, Issue 2, 2011, Pages 123-128

  Day, Anthony J ^a   Clark, Simon J ^a   Bishop, Paul N ^b,c  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

^b UNIVERSITY OF MANCHESTER   (United Kingdom)

^c UNIVERSITY OF MANCHESTER   (United Kingdom)

Author keywords

age related macular degeneration; Bruch's membrane; complement dysregulation; complement factor H; glycosaminoglycans

Indexed keywords

COMPLEMENT COMPONENT C5; COMPLEMENT COMPONENT C5A; COMPLEMENT REGULATORY PROTEIN FACTOR H; ECULIZUMAB; GLYCOSAMINOGLYCAN; PLASMA PROTEIN; UNCLASSIFIED DRUG;

AMINO ACID SUBSTITUTION; BRUCH MEMBRANE; COMPLEMENT ACTIVATION; DNA POLYMORPHISM; DRUG MECHANISM; DRUG TARGETING; DRUSEN; GENE DELETION; GENE FUNCTION; GENE IDENTIFICATION; GENETIC ASSOCIATION; HUMAN; IMMUNOPATHOGENESIS; IMMUNOREGULATION; INNATE IMMUNITY; MOLECULAR PATHOLOGY; NONHUMAN; PLASMA PROTEIN BINDING; PROTEIN CARBOHYDRATE INTERACTION; PROTEIN PROTEIN INTERACTION; RETINA MACULA AGE RELATED DEGENERATION; REVIEW;

EID: 79955071843     PISSN: 17469899     EISSN: 17469902     Source Type: Journal    
DOI: 10.1586/eop.11.10     Document Type: Review

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