Synthesis, antitumor activity, and structure-activity relationship of some 4H-pyrano[3,2-h]quinoline and 7H-pyrimido[4′,5′:6,5]pyrano[3,2-h] quinoline derivatives

Medicinal Chemistry Research

Volumn 22, Issue 3, 2013, Pages 1339-1355

  El Agrody, Ahmed M ^a   Abd Rabboh, Hisham S M ^a   Al Ghamdi, Abdullah M ^a  

^a KING KHALID UNIVERSITY   (Saudi Arabia)

Author keywords

4H pyrano 3,2 h quinoline; 7H pyrimido 4 ,5 :6,5 pyrano 3, 2 h quinoline; 8 Hydroxy 2 methylquinoline; 8 Hydroxyquinoline; Antitumor; SAR

Indexed keywords

2 (AMINOMETHYLENEAMINO) 4 (4 BROMOPHENYL) 9 METHYL 4H PYRANO[3,2 H]QUINOLINE 3 CARBONITRILE; 2 (AMINOMETHYLENEAMINO) 4 (4 CHLOROPHENYL) 4H PYRANO[3,2 H]QUINOLINE 3 CARBONITRILE; 2 (AMINOMETHYLENEAMINO) 4 (4 CHLOROPHENYL) 9 METHYL 4H PYRANO[3,2 H]QUINOLINE 3 CARBONITRILE; 2 ACETYLAMINO 4 (4 BROMOPHENYL) 9 METHYL 4H PYRANO[3,2 H]QUINOLINE 3 CARBONITRILE; 2 ACETYLAMINO 4 (4 CHLOROPHENYL) 9 METHYL 4H PYRANO[3,2 H]QUINOLINE 3 CARBONITRILE; 2 AMINO 4 (4 BROMOPHENYL) 4H PYRANO[3,2 H]QUINOLINE 3 CARBONITRILE; 2 AMINO 4 (4 BROMOPHENYL) 9 METHYL 4H PYRANO[3,2 H]QUINOLINE 3 CARBONITRILE; 2 AMINO 4 (4 CHLOROPHENYL) 4H PYRANO[3,2 H]QUINOLINE 3 CARBONITRILE; 2 AMINO 4 (4 CHLOROPHENYL) 9 METHYL 4H PYRANO[3,2 H]QUINOLINE 3 CARBONITRILE; 2 BENZYLIDENEAMINO 4 (4 CHLOROPHENYL) 4H PYRANO[3,2 H]QUINOLINE 3 CARBONITRILE; 4 (4 BROMOPHENYL) 2 ETHOXYMETHYLENEAMINO 9 METHYL 4H PYRANO[3,2 H]QUINOLINE 3 CARBONITRILE; 4 (4 CHLOROPHENYL) 2 (HYDRAZINOMETHYLENEAMINO) 4H PYRANO[3,2 H]QUINOLINE 3 CARBONITRILE; 4 (4 CHLOROPHENYL) 2 (METHYLAMINOMETHYLENEAMINO) 4H PYRANO[3,2 H]QUINOLINE 3 CARBONITRILE; 4 (4 CHLOROPHENYL) 2 DIMETHYLAMINOMETHYLENEAMINO 4H PYRANO[3,2 H]QUINOLINE 3 CARBONITRILE; 4 (4 CHLOROPHENYL) 2 DIMETHYLAMINOMETHYLENEAMINO 9 METHYL 4H PYRANO[3,2 H]QUINOLINE 3 CARBONITRILE; 4 (4 CHLOROPHENYL) 2 ETHOXYMETHYLENEAMINO 4H PYRANO[3,2 H]QUINOLINE 3 CARBONITRILE; 4 (4 CHLOROPHENYL) 2 ETHOXYMETHYLENEAMINO 9 METHYL 4H PYRANO[3,2 H]QUINOLINE 3 CARBONITRILE; 8 AMINO 7 (4 BROMOPHENYL) 2 METHYL 7H PYRIMIDO[4',5':6,5]PYRANO[3,2 H]QUINOLINE; 8 AMINO 7 (4 CHLOROPHENYL) 2 METHYL 7H PYRIMIDO[4',5':6,5]PYRANO[3,2 H]QUINOLINE; 8 AMINO 7 (4 CHLOROPHENYL) 7H PYRIMIDO[4',5':6,5]PYRANO[3,2 H]QUINOLINE; QUINOLINE DERIVATIVE; UNCLASSIFIED DRUG; VINBLASTINE;

ANTINEOPLASTIC ACTIVITY; ARTICLE; BREAST ADENOCARCINOMA; CANCER INHIBITION; CARBON NUCLEAR MAGNETIC RESONANCE; CELL VIABILITY; CONTROLLED STUDY; DRUG STRUCTURE; DRUG SYNTHESIS; ELECTROPHILICITY; HUMAN; HUMAN CELL; INFRARED SPECTROMETRY; LIVER CELL CARCINOMA; LUNG CARCINOMA; MASS SPECTROMETRY; NUCLEOPHILICITY; STRUCTURE ACTIVITY RELATION;

EID: 84874114867     PISSN: 10542523     EISSN: 15548120     Source Type: Journal    
DOI: 10.1007/s00044-012-0142-7     Document Type: Article

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