Synthesis and antitumor activities of certain novel 2-amino-9-(4-halostyryl)-4H-pyrano[3,2-h]quinoline derivatives

Medicinal Chemistry Research

Volumn 21, Issue 12, 2012, Pages 4200-4213

  El Agrody, Ahmed M ^a   Khattab, Essam Shawky A E H ^a   Fouda, Ahmed M ^a   Al Ghamdi, Abdullah M ^a  

^a KING KHALID UNIVERSITY   (Saudi Arabia)

Author keywords

(E) 2 (4 chloro bromo fluorostyryl) 8 hydroxyquinoline; 4H pyrano 3,2 h quinolines; Antitumor; Ethyl cyano p chloro bromocinnamates; SAR; Cyano p chloro bromocinnamonitriles

Indexed keywords

2 (4 BROMOSTYRYL) 8 HYDROXYQUINOLINE; 2 (4 CHLOROSTYRYL) 8 HYDROXYQUINOLINE; 2 (4 FLUOROSTYRYL) 8 HYDROXYQUINOLINE; 2 AMINO 4 (4 BROMOOPHENYL) 9 (4 FLUOROSTYRYL) 4H PYRANO[3,2 H]QUINOLINE 3 CARBONITRILE; 2 AMINO 4 (4 BROMOPHENYL) 9 (4 BROMOSTYRYL) 4H PYRANO[3,2 H]QUINOLINE 3 CARBONITRILE; 2 AMINO 4 (4 BROMOPHENYL) 9 (4 CHLOROSTYRYL) 4H PYRANO[3,2 H]QUINOLINE 3 CARBONITRILE; 2 AMINO 4 (4 CHLOROPHENYL) 9 (4 BROMOSTYRYL) 4H PYRANO[3,2 H]QUINOLINE 3 CARBONITRILE; 2 AMINO 4 (4 CHLOROPHENYL) 9 (4 CHLOROSTYRYL)( PYRANO[3,2 H]QUINOLINE 3 CARBONITRILE; 2 AMINO 4 (4 CHLOROPHENYL) 9 (4 FLUOROSTYRYL) 4H PYRANOL[3,2 H]QUINOLINE 3 CARBONITRILE; 8 ACETOXY 2 (4 BROMOSTYRYL)QUINOLINE; 8 ACETOXY 2 (4 CHLOROSTYRYL)QUINOLINE; 8 HYDROXY 2 METHYLQUINOLINE; ANTINEOPLASTIC AGENT; ETHYL 2 AMINO 4 (4 BROMOPHENYL) 9 (4 BROMOSTYRYL) 4H PYRANO[3,2 H]QUINOLINE 3 CARBOXYLATE; ETHYL 2 AMINO 4 (4 BROMOPHENYL) 9 (4 CHLOROSTYRYL) 4H PYRANO[3,2 H]QUINOLINE 3 CARBOXYLATE; ETHYL 2 AMINO 4 (4 BROMOPHENYL) 9 (4 FLUOROSTYRYL) 4H PYRANO[3,2 H]QUINOLINE 3 CARBOXYLATE; ETHYL 2 AMINO 4 (4 CHLOROPHENYL) 9 (4 BROMOSTYRYL) 4H PYRANO[3,2 H]QUINOLINE 3 CARBOXYLATE; ETHYL 2 AMINO 4 (4 CHLOROPHENYL) 9 (4 CHLOROSTYRYL) 4H PYRANO[3,2 H]QUINOLINE 3 CARBOXYLATE; ETHYL 2 AMINO 4 (4 CHLOROPHENYL) 9 (4 FLUOROSTYRYL) 4H PYRANO[3,2 H]QUINOLINE 3 CARBOXYLATE; QUINOLINE DERIVATIVE; UNCLASSIFIED DRUG; VINBLASTINE;

ANTINEOPLASTIC ACTIVITY; ARTICLE; BREAST ADENOCARCINOMA; CANCER CHEMOTHERAPY; CARBON NUCLEAR MAGNETIC RESONANCE; CELL VIABILITY; COMPARATIVE STUDY; CONTROLLED STUDY; CYTOTOXICITY; DRUG MECHANISM; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; HUMAN CELL; IC50; LIVER CELL CARCINOMA; LUNG CARCINOMA; MCF-7 CELL LINE; MELTING POINT; PROTON NUCLEAR MAGNETIC RESONANCE; STRUCTURE ACTIVITY RELATION;

EID: 84855179452     PISSN: 10542523     EISSN: 15548120     Source Type: Journal    
DOI: 10.1007/s00044-011-9965-x     Document Type: Article

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