Synthesis of 4H-chromene, coumarin, 12H-chromeno[2,3-d]pyrimidine derivatives and some of their antimicrobial and cytotoxicity activities

European Journal of Medicinal Chemistry

Volumn 46, Issue 2, 2011, Pages 765-772

  Sabry, Nermien M ^a   Mohamed, Hany M ^b   Khattab, Essam Shawky A E H ^a   Motlaq, Shymaa S ^a   El Agrody, Ahmed M ^a  

^a KING KHALID UNIVERSITY   (Saudi Arabia)

^b JAZAN UNIVERSITY   (Saudi Arabia)

Author keywords

Cyanocinnamonitriles; 12H Chromeno 2,3 d pyrimidine; 3 N,N Diethylaminophenol; 4H Chromene; Antimicrobial; Coumarin; Cytotoxicity; Ethyl cyanocinnamates

Indexed keywords

2 AMINO 4 (4 BROMOPHENYL) 7 (DIETHYLAMINO) 4H CHROMENE 3 CARBONITRILE; 2 AMINO 4 (4 CHLOROPHENYL) 7 (DIETHYLAMINO) 4H CHROMENE 3 CARBONITRILE; 2 AMINO 4 (4 FLUOROPHENYL) 7 (DIETHYLAMINO) 4H CHROMENE 3 CARBONITRILE; 2 BENZYLIDENEAMINO 4 (4 CHLOROPHENYL) 7 (DIETHYLAMINO) 4H CHROMENE 3 CARBONITRILE; 2 DIACETYLAMINO 4 (4 CHLOROPHENYL) 7 (DIETHYLAMINO) 4H CHROMENE 3 CARBONITRILE; 2 DIMETHYLAMINOMETHYLENEAMINO 4 (4 CHLOROPHENYL) 8 (DIETHYLAMINO) 4H CHROMENE 3 CARBONITRILE; 3 AMINO 5 (4 BROMOPHENYL) 8 (DIETHYLAMINO) 4 IMINO 3,4 DIHYDRO 5H CHROMENO[2,3 D]PYRIMIDINE; 3 AMINO 5 (4 CHLOROPHENYL) 8 (DIETHYLAMINO) 4 IMINO 3,4 DIHYDRO 5H CHROMENO[2,3D]PYRIMIDINE; 4 (4 BROMOPHENYL) 7 (DIETHYLAMINO) 2 ETHOXYMETHYLENEAMINO 4H CHROMENE 3 CARBONITRILE; 4 (4 BROMOPHENYL) 7 (DIETHYLAMINO) COUMARIN 3 CARBONITRILE; 4 (4 CHLOROPHENYL) 7 (DIETHYLAMINO) 2 ETHOXYMETHYLENEAMINO 4H CHROMENE 3 CARBONITRILE; 4 (4 CHLOROPHENYL) 7 (DIETHYLAMINO) COUMARIN 3 CARBONITRILE; 4 (4 FLUOROMOPHENYL) 7 (DIETHYLAMINO) COUMARIN 3 CARBONITRILE; 4 AMINO 5 (4 CHLOROPHENYL) 8 (DIETHYLAMINO) 5H CHROMENO[2,3 D]PYRIMIDINE; 5 (4 CHLOROPHENYL) 8 (DIETHYLAMINO) 2 METHYL 3,4 DIHYDRO 5H CHROMENO[2,3 D]PYRIMIDIN 4 ONE; 5 (4 CHLOROPHENYL) 8 (DIETHYLAMINO) 4 IMINO 3 METHYL 3,4 DIHYDRO 5H CHROMENO[2,3 D]PYRIMIDINE; 5 (4 CHLOROPHENYL) N,N DIETHYL 2 METHYL 4 OXO 4,5 DIHYDRO 3H CHROMENO[2,3 D]PYRIMIDIN 8 AMINIUM ACETATE; AMPICILLIN; ANTIFUNGAL AGENT; ANTIINFECTIVE AGENT; ANTINEOPLASTIC AGENT; CHROMENE DERIVATIVE; COUMARIN DERIVATIVE; ETHYL 2 AMINO 4 (4 BROMOPHENYL) 7 (DIETHYLAMINO) 4H CHROMENE 3 CARBOXYLATE; ETHYL 2 AMINO 4 (4 CHLOROPHENYL) 7 (DIETHYLAMINO) 4H CHROMENE 3 CARBOXYLATE; ETHYL 2 AMINO 4 (4 FLUOROPHENYL) 7 (DIETHYLAMINO) 4H CHROMENE 3 CARBOXYLATE; N' [4 (4 CHLOROPHENYL) 3 CYANO 7 (DIETHYLAMINO) 4H CHROMEN 2 YL]FORMIMIDAMIDE; NYSTATIN; PYRIMIDINE DERIVATIVE; UNCLASSIFIED DRUG;

ANTIBACTERIAL ACTIVITY; ANTIFUNGAL ACTIVITY; ANTIMICROBIAL ACTIVITY; ANTINEOPLASTIC ACTIVITY; ARTICLE; BACILLUS PUMILUS; BACILLUS SUBTILIS; BORDETELLA BRONCHISEPTICA; CANCER INHIBITION; CANDIDA ALBICANS; CARBON NUCLEAR MAGNETIC RESONANCE; CYTOTOXICITY; DRUG SCREENING; DRUG STRUCTURE; ESCHERICHIA COLI; HUMAN; HUMAN CELL; INFRARED SPECTROSCOPY; MASS SPECTROMETRY; NONHUMAN; PROTON NUCLEAR MAGNETIC RESONANCE; SACCHAROMYCES CEREVISIAE; STAPHYLOCOCCUS AUREUS; STAPHYLOCOCCUS EPIDERMIDIS; TUMOR CELL; ULTRAVIOLET SPECTROSCOPY;

ANTI-BACTERIAL AGENTS; ANTIFUNGAL AGENTS; ANTINEOPLASTIC AGENTS; BACTERIA; BENZOPYRANS; CELL LINE, TUMOR; CELL PROLIFERATION; COUMARINS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SCREENING ASSAYS, ANTITUMOR; FUNGI; HUMANS; MICROBIAL SENSITIVITY TESTS; MOLECULAR STRUCTURE; PYRIMIDINES; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 79151483231     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2010.12.015     Document Type: Article

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