Deficiency in pulmonary surfactant proteins in mice with fatty acid binding protein 4-Cre-mediated knockout of the tuberous sclerosis complex 1 gene

Experimental Physiology

Volumn 98, Issue 3, 2013, Pages 830-841

  Xiang, Xinxin ^a   Yuan, Fang ^a   Zhao, Jing ^a   Li, Ziru ^a   Wang, Xian ^a   Guan, Youfei ^a   Tang, Chaoshu ^a   Sun, Guang ^b   Li, Yin ^a   Zhang, Weizhen ^a,c  

^a PEKING UNIVERSITY HEALTH SCIENCE CENTER   (China)

^b MEMORIAL UNIVERSITY OF NEWFOUNDLAND   (Canada)

^c UNIVERSITY OF MICHIGAN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FATTY ACID BINDING PROTEIN 4; MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 1; RAPAMYCIN; SURFACTANT PROTEIN A; SURFACTANT PROTEIN B; TUBERIN; TUBEROUS SCLEROSIS COMPLEX 1; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL GROWTH; CONTROLLED STUDY; GENETIC TRANSCRIPTION; LUNG PARENCHYMA; MOUSE; NEWBORN; NONHUMAN; NUCLEOTIDE SEQUENCE; PHENOTYPE; PROTEIN EXPRESSION; PROTEIN SYNTHESIS; SURVIVAL RATE; SURVIVAL TIME; TUBEROUS SCLEROSIS;

EID: 84874067147     PISSN: 09580670     EISSN: 1469445X     Source Type: Journal    
DOI: 10.1113/expphysiol.2012.069674     Document Type: Article

References (47)

1. Abel ED, Peroni O, Kim JK, Kim YB, Boss O, Hadro E, Minnemann T, Shulman GI & Kahn BB (2001). Adipose-selective targeting of the GLUT4 gene impairs insulin action in muscle and liver. Nature 409, 729-733.
2. Avery ME & Mead J (1959). Surface properties in relation to aletectasis and hyaline membrane disease. Am J Dis Child 97, 517-523.
3. Barlow C, Schroeder M, Lekstrom-Himes J, Kylefjord H, Deng CX, Wynshaw-Boris A, Spiegelman BM & Xanthopoulos KG (1997). Targeted expression of Cre recombinase to adipose tissue of transgenic mice directs adipose-specific excision of loxP-flanked gene segments. Nucleic Acids Res 25, 2543-2545.
4. Biron-Shental T, Schaiff WT, Ratajczak CK, Bildirici I, Nelson DM & Sadovsky Y (2007). Hypoxia regulates the expression of fatty acid-binding proteins in primary term human trophoblasts. Am J Obstet Gynecol 197, 516.e1-516.e6.
5. Boiteux G, Lascombe I, Roche E, Plissonnier ML, Clairotte A, Bittard H & Fauconnet S (2009). A-FABP, a candidate progression marker of human transitional cell carcinoma of the bladder, is differentially regulated by PPAR in urothelial cancer cells. Int J Cancer 124, 1820-1828.
6. Borkowska J, Schwartz RA, Kotulska K & Jozwiak S (2011). Tuberous sclerosis complex: tumors and tumorigenesis. Int J Dermatol 50, 13-20.
7. Catania C, Binder E & Cota D (2011). mTORC1 signaling in energy balance and metabolic disease. Int J Obes (Lond) 35, 751-761.
8. Colombani J, Raisin S, Pantalacci S, Radimerski T, Montagne J & Léopold P (2003). A nutrient sensor mechanism controls Drosophila growth. Cell 114, 739-749.
9. Cota D (2009). Mammalian target of rapamycin complex 1 (mTORC1) signaling in energy balance and obesity. Physiol Behav 97, 520-524.
10. Cota D, Matter EK, Woods SC & Seeley RJ (2008). The role of hypothalamic mammalian target of rapamycin complex 1 signaling in diet-induced obesity. J Neurosci 28, 7202-7208.
11. Dunlop EA & Tee AR (2009). Mammalian target of rapamycin complex 1: signalling inputs, substrates and feedback mechanisms. Cell Signal 21, 827-835.
12. Elmasri H, Karaaslan C, Teper Y, Ghelfi E, Weng M, Ince TA, Kozakewich H, Bischoff J & Cataltepe S (2009). Fatty acid binding protein 4 is a target of VEGF and a regulator of cell proliferation in endothelial cells. FASEB J 23, 3865-3873.
13. Ferrell RE, Kimak MA, Lawrence EC & Finegold DN (2008). Candidate gene analysis in primary lymphedema. Lymphat Res Biol 6, 69-76.
14. Fraenkel M, Ketzinel-Gilad M, Ariav Y, Pappo O, Karaca M, Castel J, Berthault MF, Magnan C, Cerasi E, Kaiser N & Leibowitz G (2008). mTOR inhibition by rapamycin prevents β-cell adaptation to hyperglycemia and exacerbates the metabolic state in type 2 diabetes. Diabetes 57, 945-957.
15. Gangloff YG, Mueller M, Dann SG, Svoboda P, Sticker M, Spetz JF, Um SH, Brown EJ, Cereghini S, Thomas G & Kozma SC (2004). Disruption of the mouse mTOR gene leads to early postimplantation lethality and prohibits embryonic stem cell development. Mol Cell Biol 24, 9508-9516.
16. Hay N & Sonenberg N (2004). Upstream and downstream of mTOR. Genes Dev 18, 1926-1945.
17. He W, Barak Y, Hevener A, Olson P, Liao D, Le J, Nelson M, Ong E, Olefsky JM & Evans RM (2003). Adipose-specific peroxisome proliferator-activated receptor γ knockout causes insulin resistance in fat and liver but not in muscle. Proc Natl Acad Sci U S A 100, 15712-15717.
18. Iadevaia V, Huo Y, Zhang Z, Foster LJ & Proud CG (2012). Roles of the mammalian target of rapamycin, mTOR, in controlling ribosome biogenesis and protein synthesis. Biochem Soc Trans 40, 168-172.
19. Ikeda H, Shiojima I, Oka T, Yoshida M, Maemura K, Walsh K, Igarashi T & Komuro I (2011). Increased Akt-mTOR signaling in lung epithelium is associated with respiratory distress syndrome in mice. Mol Cell Biol 31, 1054-1065.
20. Kobayashi T, Minowa O, Kuno J, Mitani H, Hino O & Noda T (1999). Renal carcinogenesis, hepatic hemangiomatosis, and embryonic lethality caused by a germ-line Tsc2 mutation in mice. Cancer Res 59, 1206-1211.
21. Le Bacquer O, Petroulakis E, Paglialunga S, Poulin F, Richard D, Cianflone K & Sonenberg N (2007). Elevated sensitivity to diet-induced obesity and insulin resistance in mice lacking 4E-BP1 and 4E-BP2. J Clin Invest 117, 387-396.
22. Lee MY, Tse HF, Siu CW, Zhu SG, Man RY & Vanhoutte PM (2007). Genomic changes in regenerated porcine coronary arterial endothelial cells. Arterioscler Thromb Vasc Biol 27, 2443-2449.
23. Li Y, Jiang C, Xu G, Wang N, Zhu Y, Tang C & Wang X (2008). Homocysteine upregulates resistin production from adipocytes in vivo and in vitro. Diabetes 57, 817-827.
24. Lian J, Yan XH, Peng J & Jiang SW (2008). The mammalian target of rapamycin pathway and its role in molecular nutrition regulation. Mol Nutr Food Res 52, 393-399.
25. Miakotina OL, Goss KL & Snyder JM (2002). Insulin utilizes the PI 3-kinase pathway to inhibit SP-A gene expression in lung epithelial cells. Respir Res 3, 27.
26. Mudhasani R, Puri V, Hoover K, Czech MP, Imbalzano AN & Jones SN (2011). Dicer is required for the formation of white but not brown adipose tissue. J Cell Physiol 226, 1399-1406.
27. Murakami M, Ichisaka T, Maeda M, Oshiro N, Hara K, Edenhofer F, Kiyama H, Yonezawa K & Yamanaka S (2004). mTOR is essential for growth and proliferation in early mouse embryos and embryonic stem cells. Mol Cell Biol 24, 6710-6718.
28. Onda H, Crino PB, Zhang H, Murphey RD, Rastelli L, Gould Rothberg BE & Kwiatkowski DJ (2002). Tsc2 null murine neuroepithelial cells are a model for human tuber giant cells, and show activation of an mTOR pathway. Mol Cell Neurosci 21, 561-574.
29. Polak P, Cybulski N, Feige JN, Auwerx J, Ruegg MA & Hall MN (2008). Adipose-specific knockout of raptor results in lean mice with enhanced mitochondrial respiration. Cell Metab 8, 399-410.
30. Polak P & Hall MN (2009). mTOR and the control of whole body metabolism. Curr Opin Cell Biol 21, 209-218.
31. Reese-Wagoner A, Thompson J & Banaszak L (1999). Structural properties of the adipocyte lipid binding protein. Biochim Biophys Acta 1441, 106-116.
32. Ross SR, Graves RA, Greenstein A, Platt KA, Shyu HL, Mellovitz B & Spiegelman BM (1990). A fat-specific enhancer is the primary determinant of gene expression for adipocyte P2 in vivo. Proc Natl Acad Sci U S A 87, 9590-9594.
33. Rovira J, Marcelo Arellano E, Burke JT, Brault Y, Moya-Rull D, Bañón-Maneus E, Ramírez-Bajo MJ, Gutiérrez-Dalmau A, Revuelta I, Quintana LF, Campistol JM & Diekmann F (2008). Effect of mTOR inhibitor on body weight: from an experimental rat model to human transplant patients. Transpl Int 21, 992-998.
34. Scifres CM, Chen B, Nelson DM & Sadovsky Y (2011). Fatty acid binding protein 4 regulates intracellular lipid accumulation in human trophoblasts. J Clin Endocrinol Metab 96, E1083-E1091.
35. Shum BO, Mackay CR, Gorgun CZ, Frost MJ, Kumar RK, Hotamisligil GS & Rolph MS (2006). The adipocyte fatty acid-binding protein aP2 is required in allergic airway inflammation. J Clin Invest 116, 2183-2192.
36. Spiegelman BM & Green H (1980). Control of specific protein biosynthesis during the adipose conversion of 3T3 cells. J Biol Chem 255, 8811-8818.
37. Tomasoni R & Mondino A (2011). The tuberous sclerosis complex: balancing proliferation and survival. Biochem Soc Trans 39, 466-471.
38. Uhlmann EJ, Wong M, Baldwin RL, Bajenaru ML, Onda H, Kwiatkowski DJ, Yamada K & Gutmann DH (2002). Astrocyte-specific TSC1 conditional knockout mice exhibit abnormal neuronal organization and seizures. Ann Neurol 52, 285-296.
39. Um SH, Frigerio F, Watanabe M, Picard F, Joaquin M, Sticker M, Fumagalli S, Allegrini PR, Kozma SC, Auwerx J & Thomas G (2004). Absence of S6K1 protects against age- and diet-induced obesity while enhancing insulin sensitivity. Nature 431, 200-205.
40. Weaver TE & Whitsett JA (1991). Function and regulation of expression of pulmonary surfactant-associated proteins. Biochem J 273, 249-264
41. Weis SM & Cheresh DA (2005). Pathophysiological consequences of VEGF-induced vascular permeability. Nature 437, 497-504.
42. Whitsett JA & Weaver TE (2002). Hydrophobic surfactant proteins in lung function and disease. N Engl J Med 347, 2141-2148.
43. Wilson C, Idziaszczyk S, Parry L, Guy C, Griffiths DF, Lazda E, Bayne RA, Smith AJ, Sampson JR & Cheadle JP (2005). A mouse model of tuberous sclerosis 1 showing background specific early post-natal mortality and metastatic renal cell carcinoma. Hum Mol Genet 14, 1839-1850.
44. Wright JR (2003). Pulmonary surfactant: a front line of lung host defense. J Clin Invest 111, 1453-1455.
45. Xu G, Li Y, An W, Li S, Guan Y, Wang N, Tang C, Wang X, Zhu Y, Li X, Mulholland MW & Zhang W (2009). Gastric mammalian target of rapamycin signaling regulates ghrelin production and food intake. Endocrinology 150, 3637-3644.
46. Zhang H, Stallock JP, Ng JC, Reinhard C & Neufeld TP (2000). Regulation of cellular growth by the Drosophila target of rapamycin dTOR. Genes Dev 14, 2712-2724.
47. Zhang J, Wang Y, Gao Z, Yun Z & Ye J (2012). Hypoxia-inducible factor 1 activation from adipose protein 2-cre mediated knockout of von Hippel-Lindau gene leads to embryonic lethality. Clin Exp Pharmacol Physiol 39, 145-150.