Targeted expression of Cre recombinase to adipose tissue of transgenic mice directs adipose-specific excision of loxP-flanked gene segments

Nucleic Acids Research

Volumn 25, Issue 12, 1997, Pages 2543-2545

  Barlow, Carrolee ^a   Schroeder, Mona ^a,b   Lekstrom Himes, Julie ^b   Kylefjord, Helen ^b   Deng, Chu Xia ^c   Wynshaw Boris, Anthony ^a   Spiegelman, Bruce M ^d   Xanthopoulos, Kleanthis G ^b  

^a NATIONAL INSTITUTES OF HEALTH   (United States)

^b NATIONAL HUMAN GENOME RESEARCH INSTITUTE   (United States)

^c NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

^d HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; RECOMBINASE;

ADIPOSE TISSUE; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DNA RECOMBINATION; DNA SEQUENCE; ENHANCER REGION; GENE REPRESSION; GENE TARGETING; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; RECOMBINANT GENE; TISSUE SPECIFICITY; TRANSGENIC MOUSE;

ADIPOSE TISSUE; ANIMALS; CROSSES, GENETIC; ENHANCER ELEMENTS (GENETICS); GENETIC TECHNIQUES; INTEGRASES; MICE; MICE, TRANSGENIC; PROMOTER REGIONS (GENETICS); RECOMBINATION, GENETIC; REGULATORY SEQUENCES, NUCLEIC ACID; STEM CELLS; VIRAL PROTEINS;

ANIMALIA; MAMMALIA; MUS MUSCULUS;

EID: 0030744184     PISSN: 03051048     EISSN: None     Source Type: Journal    
DOI: 10.1093/nar/25.12.2543     Document Type: Article

References (14)

1. Capeechi,M. (1994) Science, 244, 1288-1292.
2. Capecchi,M.R. (1994) Sci. Am., 270, 52-59.
3. Sternberg,N. and Hamilton,D. (1981) J. Mol. Biol., 150, 467-486.
4. Sauer,B. and Henderson,N. (1988) Proc. Natl. Acad. Sci. USA, 85, 5166-5170.
5. Gu,H., Zou,Y.-R. and Rajewsky,K. (1993) Cell. 73, 1155-1164.
6. Schwenk,F., Baron,U. and Rajewsky,K. (1995) Nucleic Acids Res., 23, 5080-5081.
7. Lakso,M., Pichel,J.G., Gorman,J.R. Sauer,B.,Okamoto,Y., Lee,E., Alt,F.W. and Westphal,H. (1996) Proc. Natl. Acad. Sci. USA, 93, 5860-5865.
8. Lakso,M., Sauer,B., Mosinger,B., Lee,E.J., Manning,R.W., Yu,S.-H., Mulder,K.L. and Westphal,H. (1992) Proc. Natl. Acad. Sci. USA, 89, 6232-6236.
9. Orban,P.C., Chui,D. and Marth,J.D. (1992) Proc. Natl. Acad. Sci. USA, 89, 6861-6865.
10. Tsien,J.Z., Chen,D.E, Gerber,D., Tom,C., Mercer,E.H., Anderson,D.J., Mayford,M., Kandel,E.R. and Tonegawa,S. (1996) Cell, 87, 1317-1326.
11. Sauer,B. and Henderson,N. (1990) New Biol., 2, 441-449.
12. Ross,S.R., Graves,R.A., Greenstein,A., Platt,K.A., Shyu,H.-L., Mellovitz,B. and Spiegelman,B.M. (1990) Proc. Natl. Acad. Sci. USA, 87, 9590-9594.
13. Ross,S.A., Graves,R.A. and Spiegelman,B.M. (1993) Genes Dev., 7, 1318-1324.
14. St-Onge,L., Furth,P.A. and Gruss,P. (1996) Nucleic Acids Res., 24, 3875-3877.