Geranylgeranyl transferase regulates CXC chemokine formation in alveolar macrophages and neutrophil recruitment in septic lung injury

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 304, Issue 4, 2013, Pages

  Hasan, Zirak ^a   Rahman, Milladur ^a   Palani, Karzan ^a   Syk, Ingvar ^a   Jeppsson, Bengt ^a   Thorlacius, Henrik ^a  

^a LUND UNIVERSITY   (Sweden)

Author keywords

Chemokines; Isoprenylation; Leukocytes; Lung; Sepsis

Indexed keywords

ALPHA CHEMOKINE; CD11B ANTIGEN; CD40 LIGAND; GERANYLGERANYL TRANSFERASE; GGTI 2133; MONOCYTE CHEMOTACTIC PROTEIN 1; TRANSFERASE; TRANSFERASE INHIBITOR; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN EXPRESSION; ARTICLE; BLOOD EXAMINATION; BLOOD SAMPLING; CECUM; CELL ISOLATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENZYME INHIBITION; GENE EXPRESSION; IMMUNOREGULATION; IN VITRO STUDY; IN VIVO STUDY; LIGATION; LUNG ALVEOLUS MACROPHAGE; LUNG EDEMA; LUNG INJURY; LUNG LAVAGE; LUNG PARENCHYMA; MALE; MOUSE; NEUTROPHIL; NEUTROPHIL CHEMOTAXIS; NONHUMAN; PRIORITY JOURNAL; QUANTITATIVE ASSAY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SEPSIS; THROMBOCYTE; UPREGULATION;

ACUTE LUNG INJURY; ALKYL AND ARYL TRANSFERASES; ANIMALS; CD40 LIGAND; CHEMOKINES, CXC; IMIDAZOLES; LEUCINE; LIGATION; MACROPHAGE-1 ANTIGEN; MACROPHAGES, ALVEOLAR; MALE; MICE; MICE, INBRED C57BL; NAPHTHALENES; NEUTROPHIL INFILTRATION; NEUTROPHILS; RECEPTORS, INTERLEUKIN-8B; SEPSIS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84874056229     PISSN: 10400605     EISSN: 15221504     Source Type: Journal    
DOI: 10.1152/ajplung.00199.2012     Document Type: Article

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