Simvastatin antagonizes CD40l secretion, CXC chemokine formation, and pulmonary infiltration of neutrophils in abdominal sepsis

Journal of Leukocyte Biology

Volumn 89, Issue 5, 2011, Pages 735-742

  Zhang, Su ^a   Rahman, Milladur ^a   Zhang, Songen ^a   Qi, Zhongquan ^a   Thorlacius, Henrik ^a  

^a LUND UNIVERSITY HOSPITAL   (Sweden)

Author keywords

Lung; Platelets; Statins

Indexed keywords

1 (2 BROMOPHENYL) 3 (2 HYDROXY 4 NITROPHENYL)UREA; ALPHA CHEMOKINE; CD11B ANTIGEN; CD40 LIGAND; SIMVASTATIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL ACTIVATION; CONTROLLED STUDY; ENZYME INHIBITION; IN VITRO STUDY; LEUKOCYTE ACTIVATION; LUNG EDEMA; LUNG INFILTRATE; LUNG INJURY; LUNG PARENCHYMA; MALE; MOUSE; NEUTROPHIL CHEMOTAXIS; NONHUMAN; PRIORITY JOURNAL; SEPSIS; UPREGULATION;

ABDOMEN; ANIMALS; ANTICHOLESTEREMIC AGENTS; BLOTTING, WESTERN; CD40 LIGAND; CELL PROLIFERATION; CHEMOKINES, CXC; ENZYME-LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; MALE; MICE; MICE, INBRED C57BL; NEUTROPHIL INFILTRATION; NEUTROPHILS; PULMONARY EDEMA; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SEPSIS; SIMVASTATIN;

MUS;

EID: 79955796563     PISSN: 07415400     EISSN: None     Source Type: Journal    
DOI: 10.1189/jlb.0510279     Document Type: Article

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