Inhibition of Rho GTPases with protein prenyltransferase inhibitors prevents leukocyte recruitment to the central nervous system and attenuates clinical signs of disease in an animal model of multiple sclerosis

Journal of Immunology

Volumn 168, Issue 8, 2002, Pages 4087-4094

  Walters, Claire E ^a   Pryce, Gareth ^a   Hankey, Deborah J R ^a   Sebti, Said M ^a   Hamilton, Andrew D ^a   Baker, David ^a   Greenwood, John ^a   Adamson, Peter ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ENZYME INHIBITOR; GGTI 298; GUANOSINE TRIPHOSPHATASE; INTERCELLULAR ADHESION MOLECULE 1; N [[5 [(2 AMINO 3 MERCAPTOPROPYL)AMINO][1,1' BIPHENYL] 2 YL]CARBONYL]METHIONINE METHYL ESTER; RHO FACTOR;

ALLERGIC ENCEPHALOMYELITIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; ENDOTHELIUM CELL; LEUKOCYTE ADHERENCE; LEUKOCYTE MIGRATION; LYMPHOCYTIC INFILTRATION; MOUSE; MULTIPLE SCLEROSIS; NONHUMAN; PRENYLATION; PRIORITY JOURNAL; PROTEIN MODIFICATION; RAT; SIGNAL TRANSDUCTION; T LYMPHOCYTE;

EID: 0037090093     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.168.8.4087     Document Type: Article

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