SiRNA delivery into tumor cells by lipid-based nanoparticles composed of hydroxyethylated cholesteryl triamine

International Journal of Pharmaceutics

Volumn 443, Issue 1-2, 2013, Pages 221-229

  Hattori, Yoshiyuki ^a   Nakamura, Tsukasa ^a   Ohno, Hiroaki ^b   Fujii, Nobutaka ^b   Maitani, Yoshie ^a  

^a HOSHI UNIVERSITY   (Japan)

^b KYOTO UNIVERSITY   (Japan)

Author keywords

Cationic nanoparticles; Cholesteryl diamine; Cholesteryl triamine; siRNA delivery; Transfection

Indexed keywords

AZIRIDINE; CHOLESTEROL DERIVATIVE; CHOLESTERYL TRIAMINE; NANOPARTICLE; POLYSORBATE 80; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ARTICLE; CANCER CELL; CELL FUNCTION; CELLULAR DISTRIBUTION; CHOLESTEROL SYNTHESIS; CONFOCAL MICROSCOPY; CONTROLLED STUDY; DRUG MIXTURE; ENDOCYTOSIS; ENDOSOME; FEMALE; GENE EXPRESSION; GENE SILENCING; GENE TARGETING; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; NONVIRAL GENE DELIVERY SYSTEM; PINOCYTOSIS; PRIORITY JOURNAL; UTERINE CERVIX CARCINOMA; VORTEX MOTION;

CATIONS; CELL CULTURE TECHNIQUES; CELL LINE, TUMOR; CHOLESTEROL; DRUG CARRIERS; ENDOCYTOSIS; ETHANOLAMINES; FLOW CYTOMETRY; GENE KNOCKDOWN TECHNIQUES; HUMANS; LUCIFERASES, FIREFLY; MOLECULAR STRUCTURE; NANOPARTICLES; PARTICLE SIZE; RNA, SMALL INTERFERING; SURFACE PROPERTIES; TRANSFECTION;

EID: 84873996289     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2012.12.017     Document Type: Article

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