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Volumn 18, Issue 19, 2008, Pages 5228-5232

NaCl improves siRNA delivery mediated by nanoparticles of hydroxyethylated cationic cholesterol with amido-linker

Author keywords

Cationic nanoparticles; Caveolae mediated endocytosis; Membrane fusion; Nanoplex; PC 3 cells; siRNA delivery; Synthetic siRNA; Transfection

Indexed keywords

AMIDE; CARBAMIC ACID DERIVATIVE; CHOLESTEROL; CLATHRIN; NANOPARTICLE; SMALL INTERFERING RNA; SODIUM CHLORIDE;

EID: 52049106148     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2008.08.070     Document Type: Article
Times cited : (12)

References (21)
  • 7
    • 52049092710 scopus 로고    scopus 로고
    • Hattori, Y.; Maitani, Presented at the 11th Liposome Research Days Conference, Yokohama, Japan, July 2008; paper 176 (abstract P51).
    • Hattori, Y.; Maitani, Presented at the 11th Liposome Research Days Conference, Yokohama, Japan, July 2008; paper 176 (abstract P51).
  • 12
    • 52049125184 scopus 로고    scopus 로고
    • note
    • The particle size distributions and ζ-potentials were measured by ELA-Z2 (Otsuka Electronics Co., Ltd, Osaka, Japan) at 25 °C after diluting the dispersion to an appropriate volume with water.
  • 14
    • 52049119487 scopus 로고    scopus 로고
    • note
    • 2 humidified atmosphere.
  • 15
    • 52049098426 scopus 로고    scopus 로고
    • note
    • The sequences of siRNA used are as follows: Luc siRNA sense strand, 5′-ACAUCACGUACGCGGAAUACUUCGAAG-3′ and Luc siRNA antisense strand, 5′-UCGAAGUAUUCCGCGUACGUGAUGUAU-3′; random siRNA sense strand, 5′-CGAUUCGCUAGACCGGCUUCAUUGCAG-3′ and random siRNA antisense strand, 5′-GCAAUGAAGCCGGUCUAGCGAAUCGAU-3′.
  • 18
    • 52049118030 scopus 로고    scopus 로고
    • note
    • The anionic liposome were mixed at a molar lipid ratio of 1:1 with the nanoplexes, and leaked calcein was determined by fluorimetry using 490 nm as an excitation wavelength and 520 nm as an emission wavelength every 1 min after mixing for 30 s.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.