Folate-linked lipid-based nanoparticles for synthetic siRNA delivery in KB tumor xenografts

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 70, Issue 3, 2008, Pages 718-725

  Yoshizawa, Takashi ^a   Hattori, Yoshiyuki ^a   Hakoshima, Motoki ^a   Koga, Kimiko ^a   Maitani, Yoshie ^a  

^a HOSHI UNIVERSITY   (Japan)

Author keywords

Cationic nanoparticles; Folate receptor; Folic acid; Her 2; Nasopharyngeal tumor; Synthetic siRNA

Indexed keywords

CHOLESTERYL 3BETA CARBOXYAMIDOETHYLENE N HYDROXYETHYLAMINE; EPIDERMAL GROWTH FACTOR RECEPTOR 2; ETHANOLAMINE DERIVATIVE; FOLATE POLYETHYLENEGLYCOL DISTEAROYLPHOSHATIDYLETHANOLAMINE; FOLATE RECEPTOR; FOLIC ACID; MACROGOL; NANOPARTICLE; POLYSORBATE 80; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER GENE THERAPY; CANCER INHIBITION; GENE OVEREXPRESSION; GENE SILENCING; GENE TARGETING; MALE; MOUSE; NASOPHARYNX TUMOR; NONHUMAN; PROTEIN EXPRESSION; RNA INTERFERENCE; TUMOR XENOGRAFT;

ANIMALS; BLOTTING, WESTERN; CARRIER PROTEINS; CELL LINE, TUMOR; CELL PROLIFERATION; CELL SURVIVAL; ELECTROPHORETIC MOBILITY SHIFT ASSAY; FOLIC ACID; GENE THERAPY; HUMANS; LIPIDS; MALE; MICE; MICE, INBRED BALB C; MICE, NUDE; NANOPARTICLES; NASOPHARYNGEAL NEOPLASMS; RECEPTOR, ERBB-2; RECEPTORS, CELL SURFACE; RNA INTERFERENCE; RNA, SMALL INTERFERING; TIME FACTORS; TRANSFECTION; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 54949125913     PISSN: 09396411     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejpb.2008.06.026     Document Type: Article

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