Sulfated hyaluronan/collagen I matrices enhance the osteogenic differentiation of human mesenchymal stromal cells in vitro even in the absence of dexamethasone

Acta Biomaterialia

Volumn 8, Issue 11, 2012, Pages 4064-4072

  Hempel, U ^a   Moller S ^b   Noack, C ^a   Hintze, V ^c   Scharnweber, D ^c   Schnabelrauch, M ^b   Dieter, P ^a  

^a DRESDEN UNIVERSITY OF TECHNOLOGY   (Germany)

^b BIOMATERIALS DEPARTMENT   (Germany)

^c DRESDEN UNIVERSITY OF TECHNOLOGY   (Germany)

Author keywords

Extracellular matrix; Glycosaminoglycans; Mesenchymal stromal cells; Osteogenic differentiation; Sulfated hyaluronan

Indexed keywords

BIOMATERIALS; BONE; CALCIUM PHOSPHATE; DEPOSITION; PHOSPHATASES; SULFUR COMPOUNDS; TISSUE ENGINEERING;

COLLAGEN I; DEXAMETHASONES; EXTRACELLULAR MATRICES; GLYCOSAMINOGLYCANS; HYALURONAN; MATRIX; MESENCHYMAL STROMAL CELLS; OSTEOGENIC DIFFERENTIATION; SULFATED HYALURONAN; SULPHATES;

HYALURONIC ACID;

ALKALINE PHOSPHATASE; BONE SIALOPROTEIN; BONE SIALOPROTEIN II; CALCIUM PHOSPHATE; CHONDROITIN 4 SULFATE; COLLAGEN TYPE 1; DEXAMETHASONE; GLYCOSAMINOGLYCAN POLYSULFATE; HYALURONIC ACID; HYDROXYL GROUP; N ACETYLGLUCOSAMINE; OSTEOCALCIN; SULFATED HYALURONAN DERIVATIVE; TISSUE NON SPECIFIC ALKALINE PHOSPHATASE; TRANSCRIPTION FACTOR RUNX2; UNCLASSIFIED DRUG; GLYCOSAMINOGLYCAN; SULFATE;

ADULT; ARTICLE; ARTIFICIAL EXTRACELLULAR MATRIX; BONE DEVELOPMENT; CELL DIFFERENTIATION; CONTROLLED STUDY; ENZYME ACTIVITY; EXTRACELLULAR MATRIX; HUMAN; HUMAN CELL; IN VITRO STUDY; MALE; MESENCHYMAL STROMA CELL; NORMAL HUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SULFATION; ANIMAL; CHEMISTRY; CYTOLOGY; DRUG EFFECT; ENZYMOLOGY; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; RAT; STAINING; SYNTHESIS;

HYAS;

ADULT; ALKALINE PHOSPHATASE; ANIMALS; CALCIUM PHOSPHATES; CELL DIFFERENTIATION; COLLAGEN TYPE I; CORE BINDING FACTOR ALPHA 1 SUBUNIT; DEXAMETHASONE; EXTRACELLULAR MATRIX; GENE EXPRESSION REGULATION; GLYCOSAMINOGLYCANS; HUMANS; HYALURONIC ACID; INTEGRIN-BINDING SIALOPROTEIN; MALE; MESENCHYMAL STROMAL CELLS; OSTEOCALCIN; OSTEOGENESIS; RATS; STAINING AND LABELING; SULFATES;

EID: 84873978936     PISSN: 17427061     EISSN: 18787568     Source Type: Journal    
DOI: 10.1016/j.actbio.2012.06.039     Document Type: Article

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