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Volumn 43, Issue 8, 2010, Pages 524-529

New understanding of glucocorticoid action in bone cells

Author keywords

Cytoskeleton; Glucocorticoid; Osteoblast; Osteoclast

Indexed keywords


EID: 77956510065     PISSN: 19766696     EISSN: 1976670X     Source Type: Journal    
DOI: 10.5483/BMBRep.2010.43.8.524     Document Type: Review
Times cited : (55)

References (57)
  • 1
    • 0033007352 scopus 로고    scopus 로고
    • New developments in the pathogenesis and treatment of steroid-induced osteoporosis
    • Manolagas, S. C. and Weinstein, R. S. (1999) New developments in the pathogenesis and treatment of steroid-induced osteoporosis. J. Bone Miner Res. 14, 1061-1066.
    • (1999) J. Bone Miner Res. , vol.14 , pp. 1061-1066
    • Manolagas, S.C.1    Weinstein, R.S.2
  • 2
    • 0035224983 scopus 로고    scopus 로고
    • Glucocorticoid-induced osteoporosis
    • Weinstein, R. S. (2001) Glucocorticoid-induced osteoporosis. Rev. Endocr. Metab. Disord. 2, 65-73.
    • (2001) Rev. Endocr. Metab. Disord. , vol.2 , pp. 65-73
    • Weinstein, R.S.1
  • 3
    • 0025101215 scopus 로고
    • Glucocorticoid-induced osteoporosis: pathogenesis and management
    • Lukert, B. P. and Raisz, L. G. (1990) Glucocorticoid-induced osteoporosis: pathogenesis and management. Ann. Intern. Med. 112, 352-364.
    • (1990) Ann. Intern. Med. , vol.112 , pp. 352-364
    • Lukert, B.P.1    Raisz, L.G.2
  • 4
    • 1642343232 scopus 로고    scopus 로고
    • Perspectives on glucocorticoid-induced osteoporosis
    • Canalis, E., Bilezikian, J. P., Angeli, A. and Giustina, A. (2004) Perspectives on glucocorticoid-induced osteoporosis. Bone 34, 593-598.
    • (2004) Bone , vol.34 , pp. 593-598
    • Canalis, E.1    Bilezikian, J.P.2    Angeli, A.3    Giustina, A.4
  • 5
    • 0025818875 scopus 로고
    • Intestinal calcium absorption and parathyroid hormone secretion in asthmatic patients on prolonged oral or inhaled steroid treatment
    • Luengo, M., Picado, C., Piera, C., Guanabens, N., Montserrat, J. M., Rivera, J. and Setoain, J. (1991) Intestinal calcium absorption and parathyroid hormone secretion in asthmatic patients on prolonged oral or inhaled steroid treatment. Eur. Respir. J. 4, 441-444.
    • (1991) Eur. Respir. J. , vol.4 , pp. 441-444
    • Luengo, M.1    Picado, C.2    Piera, C.3    Guanabens, N.4    Montserrat, J.M.5    Rivera, J.6    Setoain, J.7
  • 6
    • 0028865277 scopus 로고
    • Intact parathyroid hormone levels are not elevated in glucocorticoid-treated subjects
    • Paz-Pacheco, E., Fuleihan, G. E. and LeBoff, M. S. (1995) Intact parathyroid hormone levels are not elevated in glucocorticoid-treated subjects. J. Bone Miner Res. 10, 1713-1718.
    • (1995) J. Bone Miner Res. , vol.10 , pp. 1713-1718
    • Paz-Pacheco, E.1    Fuleihan, G.E.2    LeBoff, M.S.3
  • 8
    • 0021745271 scopus 로고
    • Characterization of a steroid hormone receptor gene and mRNA in wildtype and mutant cells
    • Miesfeld, R., Okret, S., Wikstrom, A. C., Wrange, O., Gustafsson, J. A. and Yamamoto, K. R. (1984) Characterization of a steroid hormone receptor gene and mRNA in wildtype and mutant cells. Nature 312, 779-781.
    • (1984) Nature , vol.312 , pp. 779-781
    • Miesfeld, R.1    Okret, S.2    Wikstrom, A.C.3    Wrange, O.4    Gustafsson, J.A.5    Yamamoto, K.R.6
  • 9
    • 18144424777 scopus 로고    scopus 로고
    • Gene regulation by the glucocorticoid receptor: structure: function relationship
    • Kumar, R. and Thompson, E. B. (2005) Gene regulation by the glucocorticoid receptor: structure: function relationship. J. Steroid. Biochem. Mol. Biol. 94, 383-394.
    • (2005) J. Steroid. Biochem. Mol. Biol. , vol.94 , pp. 383-394
    • Kumar, R.1    Thompson, E.B.2
  • 10
    • 0032567143 scopus 로고    scopus 로고
    • Glucocorticoid signalling--multiple variations of a common theme
    • Reichardt, H. M. and Schutz, G. (1998) Glucocorticoid signalling--multiple variations of a common theme. Mol. Cell Endocrinol. 146, 1-6.
    • (1998) Mol. Cell Endocrinol. , vol.146 , pp. 1-6
    • Reichardt, H.M.1    Schutz, G.2
  • 11
    • 0025367067 scopus 로고
    • Two genetically defined transacting loci coordinately regulate overlapping sets of liver-specific genes
    • Ruppert, S., Boshart, M., Bosch, F. X., Schmid, W., Fournier, R. E. and Schutz, G. (1990) Two genetically defined transacting loci coordinately regulate overlapping sets of liver-specific genes. Cell 61, 895-904.
    • (1990) Cell , vol.61 , pp. 895-904
    • Ruppert, S.1    Boshart, M.2    Bosch, F.X.3    Schmid, W.4    Fournier, R.E.5    Schutz, G.6
  • 12
    • 0027402820 scopus 로고
    • Novel glucocorticoid receptor complex with DNA element of the hormone-repressed POMC gene
    • Drouin, J., Sun, Y. L., Chamberland, M., Gauthier, Y., De Lean, A., Nemer, M. and Schmidt, T. J. (1993) Novel glucocorticoid receptor complex with DNA element of the hormone-repressed POMC gene. EMBO J. 12, 145-156.
    • (1993) EMBO J , vol.12 , pp. 145-156
    • Drouin, J.1    Sun, Y.L.2    Chamberland, M.3    Gauthier, Y.4    De Lean, A.5    Nemer, M.6    Schmidt, T.J.7
  • 13
    • 0025804498 scopus 로고
    • The glucocorticoid receptor binds to a sequence overlapping the TATA box of the human osteocalcin promoter: a potential mechanism for negative regulation
    • Stromstedt, P. E., Poellinger, L., Gustafsson, J. A. and Carlstedt-Duke, J. (1991) The glucocorticoid receptor binds to a sequence overlapping the TATA box of the human osteocalcin promoter: a potential mechanism for negative regulation. Mol. Cell Biol. 11, 3379-3383.
    • (1991) Mol. Cell Biol. , vol.11 , pp. 3379-3383
    • Stromstedt, P.E.1    Poellinger, L.2    Gustafsson, J.A.3    Carlstedt-Duke, J.4
  • 14
    • 39549107784 scopus 로고    scopus 로고
    • Glucocorticoid repression of human with-no-lysine (K) kinase-4 gene expression is mediated by the negative response elements in the promoter
    • Li, C., Li, Y., Liu, H., Sun, Z., Lu, J. and Zhao, Y. (2008) Glucocorticoid repression of human with-no-lysine (K) kinase-4 gene expression is mediated by the negative response elements in the promoter. J. Mol. Endocrinol. 40, 3-12.
    • (2008) J. Mol. Endocrinol. , vol.40 , pp. 3-12
    • Li, C.1    Li, Y.2    Liu, H.3    Sun, Z.4    Lu, J.5    Zhao, Y.6
  • 15
    • 33947196913 scopus 로고    scopus 로고
    • Glucocorticoids in the regulation of transcription factors that control cytokine synthesis
    • Liberman, A. C., Druker, J., Perone, M. J. and Arzt, E. (2007) Glucocorticoids in the regulation of transcription factors that control cytokine synthesis. Cytokine Growth Factor Rev. 18, 45-56.
    • (2007) Cytokine Growth Factor Rev , vol.18 , pp. 45-56
    • Liberman, A.C.1    Druker, J.2    Perone, M.J.3    Arzt, E.4
  • 16
    • 70349316336 scopus 로고    scopus 로고
    • Glucocorticoids inhibit GATA-3 phosphorylation and activity in T cells
    • Liberman, A. C., Druker, J., Refojo, D., Holsboer, F. and Arzt, E. (2009) Glucocorticoids inhibit GATA-3 phosphorylation and activity in T cells. FASEB J. 23, 1558-1571.
    • (2009) FASEB J , vol.23 , pp. 1558-1571
    • Liberman, A.C.1    Druker, J.2    Refojo, D.3    Holsboer, F.4    Arzt, E.5
  • 17
    • 33947655345 scopus 로고    scopus 로고
    • The activated glucocorticoid receptor inhibits the transcription factor T-bet by direct protein-protein interaction
    • Liberman, A. C., Refojo, D., Druker, J., Toscano, M., Rein, T., Holsboer, F. and Arzt, E. (2007) The activated glucocorticoid receptor inhibits the transcription factor T-bet by direct protein-protein interaction. FASEB J. 21, 1177-1188.
    • (2007) FASEB J , vol.21 , pp. 1177-1188
    • Liberman, A.C.1    Refojo, D.2    Druker, J.3    Toscano, M.4    Rein, T.5    Holsboer, F.6    Arzt, E.7
  • 19
    • 0032528180 scopus 로고    scopus 로고
    • Inhibition of osteoblastogenesis and promotion of apoptosis of osteoblasts and osteocytes by glucocorticoids Potential mechanisms of their deleterious effects on bone
    • Weinstein, R. S., Jilka, R. L., Parfitt, A. M. and Manolagas, S. C. (1998) Inhibition of osteoblastogenesis and promotion of apoptosis of osteoblasts and osteocytes by glucocorticoids. Potential mechanisms of their deleterious effects on bone. J. Clin. Invest. 102, 274-282.
    • (1998) J. Clin. Invest. , vol.102 , pp. 274-282
    • Weinstein, R.S.1    Jilka, R.L.2    Parfitt, A.M.3    Manolagas, S.C.4
  • 20
    • 40949152998 scopus 로고    scopus 로고
    • Regulation of bim in glucocorticoid-mediated osteoblast apoptosis
    • Espina, B., Liang, M., Russell, R. G. and Hulley, P. A. (2008) Regulation of bim in glucocorticoid-mediated osteoblast apoptosis. J. Cell Physiol. 215, 488-496.
    • (2008) J. Cell Physiol. , vol.215 , pp. 488-496
    • Espina, B.1    Liang, M.2    Russell, R.G.3    Hulley, P.A.4
  • 22
    • 1642303117 scopus 로고    scopus 로고
    • Basic helix-loop-helix proteins bind to TrkB and p21(Cip1) promoters linking differentiation and cell cycle arrest in neuroblastoma cells
    • Liu, Y., Encinas, M., Comella, J. X., Aldea, M. and Gallego, C. (2004) Basic helix-loop-helix proteins bind to TrkB and p21(Cip1) promoters linking differentiation and cell cycle arrest in neuroblastoma cells. Mol. Cell Biol. 24, 2662-2672.
    • (2004) Mol. Cell Biol. , vol.24 , pp. 2662-2672
    • Liu, Y.1    Encinas, M.2    Comella, J.X.3    Aldea, M.4    Gallego, C.5
  • 23
    • 1642546419 scopus 로고    scopus 로고
    • Glucocorticoids act directly on osteoblasts and osteocytes to induce their apoptosis and reduce bone formation and strength
    • O'Brien, C. A., Jia, D., Plotkin, L. I., Bellido, T., Powers, C. C., Stewart, S. A., Manolagas, S. C. and Weinstein, R. S. (2004) Glucocorticoids act directly on osteoblasts and osteocytes to induce their apoptosis and reduce bone formation and strength. Endocrinology 145, 1835-1841.
    • (2004) Endocrinology , vol.145 , pp. 1835-1841
    • O'Brien, C.A.1    Jia, D.2    Plotkin, L.I.3    Bellido, T.4    Powers, C.C.5    Stewart, S.A.6    Manolagas, S.C.7    Weinstein, R.S.8
  • 24
    • 0037124070 scopus 로고    scopus 로고
    • Glucocorticoids inhibit cell cycle progression in differentiating osteoblasts via glycogen synthase kinase-3beta
    • Smith, E., Coetzee, G. A. and Frenkel, B. (2002) Glucocorticoids inhibit cell cycle progression in differentiating osteoblasts via glycogen synthase kinase-3beta. J. Biol. Chem. 277, 18191-18197.
    • (2002) J. Biol. Chem. , vol.277 , pp. 18191-18197
    • Smith, E.1    Coetzee, G.A.2    Frenkel, B.3
  • 25
    • 0029821686 scopus 로고    scopus 로고
    • Clinical review 83 mechanisms of glucocorticoid action in bone: implications to glucocorticoid-induced osteoporosis
    • Canalis, E. (1996) Clinical review 83: mechanisms of glucocorticoid action in bone: implications to glucocorticoid-induced osteoporosis. J. Clin. Endocrinol. Metab. 81, 3441-3447.
    • (1996) J. Clin. Endocrinol. Metab. , vol.81 , pp. 3441-3447
    • Canalis, E.1
  • 26
    • 0036256989 scopus 로고    scopus 로고
    • Effects of cortisol and bone morphogenetic protein-2 on stromal cell differentiation: correlation with CCAAT-enhancer binding protein expression
    • Pereira, R. C., Delany, A. M. and Canalis, E. (2002) Effects of cortisol and bone morphogenetic protein-2 on stromal cell differentiation: correlation with CCAAT-enhancer binding protein expression. Bone 30, 685-691.
    • (2002) Bone , vol.30 , pp. 685-691
    • Pereira, R.C.1    Delany, A.M.2    Canalis, E.3
  • 27
    • 0035047358 scopus 로고    scopus 로고
    • Cortisol inhibits the differentiation and apoptosis of osteoblasts in culture
    • Pereira, R. M., Delany, A. M. and Canalis, E. (2001) Cortisol inhibits the differentiation and apoptosis of osteoblasts in culture. Bone 28, 484-490.
    • (2001) Bone , vol.28 , pp. 484-490
    • Pereira, R.M.1    Delany, A.M.2    Canalis, E.3
  • 28
    • 33751534268 scopus 로고    scopus 로고
    • Glucocorticoids induce the differentiation of a mesenchymal progenitor cell line, ROB-C26 into adipocytes and osteoblasts, but fail to induce terminal osteoblast differentiation
    • Ito, S., Suzuki, N., Kato, S., Takahashi, T. and Takagi, M. (2007) Glucocorticoids induce the differentiation of a mesenchymal progenitor cell line, ROB-C26 into adipocytes and osteoblasts, but fail to induce terminal osteoblast differentiation. Bone 40, 84-92.
    • (2007) Bone , vol.40 , pp. 84-92
    • Ito, S.1    Suzuki, N.2    Kato, S.3    Takahashi, T.4    Takagi, M.5
  • 29
    • 1642464760 scopus 로고    scopus 로고
    • CCAAT/ enhancer binding protein homologous protein (DDIT3) induces osteoblastic cell differentiation
    • Pereira, R. C., Delany, A. M. and Canalis, E. (2004) CCAAT/ enhancer binding protein homologous protein (DDIT3) induces osteoblastic cell differentiation. Endocrinology 145, 1952-1960.
    • (2004) Endocrinology , vol.145 , pp. 1952-1960
    • Pereira, R.C.1    Delany, A.M.2    Canalis, E.3
  • 30
    • 0029905399 scopus 로고    scopus 로고
    • Induction of peroxisome proliferator-activated receptor gamma during the conversion of 3T3 fibroblasts into adipocytes is mediated by C/EBPbeta, C/EBPdelta, and glucocorticoids
    • Wu, Z., Bucher, N. L. and Farmer, S. R. (1996) Induction of peroxisome proliferator-activated receptor gamma during the conversion of 3T3 fibroblasts into adipocytes is mediated by C/EBPbeta, C/EBPdelta, and glucocorticoids. Mol. Cell Biol. 16, 4128-4136.
    • (1996) Mol. Cell Biol. , vol.16 , pp. 4128-4136
    • Wu, Z.1    Bucher, N.L.2    Farmer, S.R.3
  • 31
    • 0033103604 scopus 로고    scopus 로고
    • Osteoprogenitor cell frequency in rat bone marrow stromal populations: role for heterotypic cell-cell interactions in osteoblast differentiation
    • Aubin, J. E. (1999) Osteoprogenitor cell frequency in rat bone marrow stromal populations: role for heterotypic cell-cell interactions in osteoblast differentiation. J. Cell Biochem. 72, 396-410.
    • (1999) J. Cell Biochem. , vol.72 , pp. 396-410
    • Aubin, J.E.1
  • 32
    • 33644906612 scopus 로고    scopus 로고
    • The essential role of glucocorticoids for proper human osteoblast differentiation and matrix mineralization
    • Eijken, M., Koedam, M., van Driel, M., Buurman, C. J., Pols, H. A. and van Leeuwen, J. P. (2006) The essential role of glucocorticoids for proper human osteoblast differentiation and matrix mineralization. Mol. Cell Endocrinol. 248, 87-93.
    • (2006) Mol. Cell Endocrinol. , vol.248 , pp. 87-93
    • Eijken, M.1    Koedam, M.2    van Driel, M.3    Buurman, C.J.4    Pols, H.A.5    van Leeuwen, J.P.6
  • 33
    • 0346250853 scopus 로고    scopus 로고
    • Sustained in vitro expansion of bone progenitors is cell density dependent
    • Purpura, K. A., Aubin, J. E. and Zandstra, P. W. (2004) Sustained in vitro expansion of bone progenitors is cell density dependent. Stem Cells 22, 39-50.
    • (2004) Stem Cells , vol.22 , pp. 39-50
    • Purpura, K.A.1    Aubin, J.E.2    Zandstra, P.W.3
  • 34
    • 0034284970 scopus 로고    scopus 로고
    • Bone resorption by osteoclasts
    • Teitelbaum, S. L. (2000) Bone resorption by osteoclasts. Science 289, 1504-1508.
    • (2000) Science , vol.289 , pp. 1504-1508
    • Teitelbaum, S.L.1
  • 35
    • 0033304809 scopus 로고    scopus 로고
    • Stimulation of osteoprotegerin ligand and inhibition of osteoprotegerin production by glucocorticoids in human osteoblastic lineage cells: potential paracrine mechanisms of glucocorticoid-induced osteoporosis
    • Hofbauer, L. C., Gori, F., Riggs, B. L., Lacey, D. L., Dunstan, C. R., Spelsberg, T. C. and Khosla, S. (1999) Stimulation of osteoprotegerin ligand and inhibition of osteoprotegerin production by glucocorticoids in human osteoblastic lineage cells: potential paracrine mechanisms of glucocorticoid-induced osteoporosis. Endocrinology 140, 4382-4389.
    • (1999) Endocrinology , vol.140 , pp. 4382-4389
    • Hofbauer, L.C.1    Gori, F.2    Riggs, B.L.3    Lacey, D.L.4    Dunstan, C.R.5    Spelsberg, T.C.6    Khosla, S.7
  • 36
    • 0031769051 scopus 로고    scopus 로고
    • Dexamethasone promotes expression of membrane-bound macrophage colony-stimulating factor in murine osteoblast-like cells
    • Rubin, J., Biskobing, D. M., Jadhav, L., Fan, D., Nanes, M. S., Perkins, S. and Fan, X. (1998) Dexamethasone promotes expression of membrane-bound macrophage colony-stimulating factor in murine osteoblast-like cells. Endocrinology 139, 1006-1012.
    • (1998) Endocrinology , vol.139 , pp. 1006-1012
    • Rubin, J.1    Biskobing, D.M.2    Jadhav, L.3    Fan, D.4    Nanes, M.S.5    Perkins, S.6    Fan, X.7
  • 37
    • 0024554774 scopus 로고
    • Bone histomorphometry in glucocorticoid-induced osteoporosis
    • Dempster, D. W. (1989) Bone histomorphometry in glucocorticoid-induced osteoporosis. J. Bone Miner Res. 4, 137-141.
    • (1989) J. Bone Miner Res. , vol.4 , pp. 137-141
    • Dempster, D.W.1
  • 39
    • 33748373423 scopus 로고    scopus 로고
    • Dexamethasone inhibits the formation of multinucleated osteoclasts via down-regulation of beta3 integrin expression
    • Kim, Y. H., Jun, J. H., Woo, K. M., Ryoo, H. M., Kim, G. S. and Baek, J. H. (2006) Dexamethasone inhibits the formation of multinucleated osteoclasts via down-regulation of beta3 integrin expression. Arch. Pharm. Res. 29, 691-698.
    • (2006) Arch. Pharm. Res. , vol.29 , pp. 691-698
    • Kim, Y.H.1    Jun, J.H.2    Woo, K.M.3    Ryoo, H.M.4    Kim, G.S.5    Baek, J.H.6
  • 41
    • 33751501004 scopus 로고    scopus 로고
    • Glucocorticoids act directly on osteoclasts to increase their life span and reduce bone density
    • Jia, D., O'Brien, C. A., Stewart, S. A., Manolagas, S. C. and Weinstein, R. S. (2006) Glucocorticoids act directly on osteoclasts to increase their life span and reduce bone density. Endocrinology 147, 5592-5599.
    • (2006) Endocrinology , vol.147 , pp. 5592-5599
    • Jia, D.1    O'Brien, C.A.2    Stewart, S.A.3    Manolagas, S.C.4    Weinstein, R.S.5
  • 43
    • 33947497852 scopus 로고    scopus 로고
    • Osteoclasts: what do they do and how do they do it? Am
    • Teitelbaum, S. L. (2007) Osteoclasts: what do they do and how do they do it? Am. J. Pathol. 170, 427-435.
    • (2007) J. Pathol. , vol.170 , pp. 427-435
    • Teitelbaum, S.L.1
  • 44
    • 0043267732 scopus 로고    scopus 로고
    • Genetic regulation of osteoclast development and function
    • Teitelbaum, S. L. and Ross, F. P. (2003) Genetic regulation of osteoclast development and function. Nat. Rev. Genet. 4, 638-649.
    • (2003) Nat. Rev. Genet. , vol.4 , pp. 638-649
    • Teitelbaum, S.L.1    Ross, F.P.2
  • 45
    • 0041731907 scopus 로고    scopus 로고
    • Dynamic changes in the osteoclast cytoskeleton in response to growth factors and cell attachment are controlled by beta3 integrin
    • Faccio, R., Novack, D. V., Zallone, A., Ross, F. P. and Teitelbaum, S. L. (2003) Dynamic changes in the osteoclast cytoskeleton in response to growth factors and cell attachment are controlled by beta3 integrin. J. Cell Biol. 162, 499-509.
    • (2003) J. Cell Biol. , vol.162 , pp. 499-509
    • Faccio, R.1    Novack, D.V.2    Zallone, A.3    Ross, F.P.4    Teitelbaum, S.L.5
  • 47
    • 34648844847 scopus 로고    scopus 로고
    • Activated c-Fms recruits Vav and Rac during CSF-1-induced cytoskeletal remodeling and spreading in osteoclasts
    • Sakai, H., Chen, Y., Itokawa, T., Yu, K. P., Zhu, M. L. and Insogna, K. (2006) Activated c-Fms recruits Vav and Rac during CSF-1-induced cytoskeletal remodeling and spreading in osteoclasts. Bone 39, 1290-1301.
    • (2006) Bone , vol.39 , pp. 1290-1301
    • Sakai, H.1    Chen, Y.2    Itokawa, T.3    Yu, K.P.4    Zhu, M.L.5    Insogna, K.6
  • 48
    • 49249104668 scopus 로고    scopus 로고
    • Rho GTPases in osteoclasts: orchestrators of podosome arrangement
    • Ory, S., Brazier, H., Pawlak, G. and Blangy, A. (2008) Rho GTPases in osteoclasts: orchestrators of podosome arrangement. Eur. J. Cell Biol. 87, 469-477.
    • (2008) Eur. J. Cell Biol. , vol.87 , pp. 469-477
    • Ory, S.1    Brazier, H.2    Pawlak, G.3    Blangy, A.4
  • 50
    • 38549113039 scopus 로고    scopus 로고
    • Identifying the relative contributions of Rac1 and Rac2 to osteoclastogenesis
    • Wang, Y., Lebowitz, D., Sun, C., Thang, H., Grynpas, M. D. and Glogauer, M. (2008) Identifying the relative contributions of Rac1 and Rac2 to osteoclastogenesis. J. Bone Miner Res. 23, 260-270.
    • (2008) J. Bone Miner Res. , vol.23 , pp. 260-270
    • Wang, Y.1    Lebowitz, D.2    Sun, C.3    Thang, H.4    Grynpas, M.D.5    Glogauer, M.6
  • 51
    • 0037069690 scopus 로고    scopus 로고
    • Rho GTPases in cell biology
    • Etienne-Manneville, S. and Hall, A. (2002) Rho GTPases in cell biology. Nature 420, 629-635.
    • (2002) Nature , vol.420 , pp. 629-635
    • Etienne-Manneville, S.1    Hall, A.2
  • 52
    • 0242384071 scopus 로고    scopus 로고
    • Vav proteins, masters of the world of cytoskeleton organization
    • Hornstein, I., Alcover, A. and Katzav, S. (2004) Vav proteins, masters of the world of cytoskeleton organization. Cell Signal 16, 1-11.
    • (2004) Cell Signal , vol.16 , pp. 1-11
    • Hornstein, I.1    Alcover, A.2    Katzav, S.3
  • 53
    • 13444252631 scopus 로고    scopus 로고
    • GEF means go: turning on RHO GTPases with guanine nucleotide-exchange factors
    • Rossman, K. L., Der, C. J. and Sondek, J. (2005) GEF means go: turning on RHO GTPases with guanine nucleotide-exchange factors. Nat. Rev. Mol. Cell Biol. 6, 167-180.
    • (2005) Nat. Rev. Mol. Cell Biol. , vol.6 , pp. 167-180
    • Rossman, K.L.1    Der, C.J.2    Sondek, J.3
  • 55
    • 0035205516 scopus 로고    scopus 로고
    • Molecular mechanisms of glucocorticoid-induced osteoporosis
    • Patschan, D., Loddenkemper, K. and Buttgereit, F. (2001) Molecular mechanisms of glucocorticoid-induced osteoporosis. Bone 29, 498-505.
    • (2001) Bone , vol.29 , pp. 498-505
    • Patschan, D.1    Loddenkemper, K.2    Buttgereit, F.3
  • 56
    • 23744515800 scopus 로고    scopus 로고
    • A novel Rho-mDia2-HDAC6 pathway controls podosome patterning through microtubule acetylation in osteoclasts
    • Destaing, O., Saltel, F., Gilquin, B., Chabadel, A., Khochbin, S., Ory, S. and Jurdic, P. (2005) A novel Rho-mDia2-HDAC6 pathway controls podosome patterning through microtubule acetylation in osteoclasts. J. Cell Sci. 118, 2901-2911.
    • (2005) J. Cell Sci. , vol.118 , pp. 2901-2911
    • Destaing, O.1    Saltel, F.2    Gilquin, B.3    Chabadel, A.4    Khochbin, S.5    Ory, S.6    Jurdic, P.7
  • 57
    • 33748168693 scopus 로고    scopus 로고
    • Coordination of microtubules and the actin cytoskeleton is important in osteoclast function, but calcitonin disrupts sealing zones without affecting microtubule networks
    • Okumura, S., Mizoguchi, T., Sato, N., Yamaki, M., Kobayashi, Y., Yamauchi, H., Ozawa, H., Udagawa, N. and Takahashi, N. (2006) Coordination of microtubules and the actin cytoskeleton is important in osteoclast function, but calcitonin disrupts sealing zones without affecting microtubule networks. Bone 39, 684-693.
    • (2006) Bone , vol.39 , pp. 684-693
    • Okumura, S.1    Mizoguchi, T.2    Sato, N.3    Yamaki, M.4    Kobayashi, Y.5    Yamauchi, H.6    Ozawa, H.7    Udagawa, N.8    Takahashi, N.9


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