Proteomics reveals multiple routes to the osteogenic phenotype in mesenchymal stem cells

BMC Genomics

Volumn 8, Issue , 2007, Pages

  Bennett, Kristin P ^a   Bergeron, Charles ^a   Acar, Evrim ^b   Klees, Robert F ^c   Vandenberg, Scott L ^d   Yener, Bülent ^b   Plopper, George E ^c  

^a Research Rensselaer Polytechnic Institute   (United States)

^b Rensselaer Polytechnic Institute   (United States)

^c RENSSELAER POLYTECHNIC INSTITUTE   (United States)

^d SIENA COLLEGE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGEN TYPE 1; KALININ; VITRONECTIN;

ARTICLE; BONE DEVELOPMENT; CELL DIFFERENTIATION; CELL FATE; GENETIC ANALYSIS; GENETIC VARIABILITY; HUMAN; HUMAN CELL; MESENCHYMAL STEM CELL; ORTHOLOGY; OSTEOBLAST; PHENOTYPE; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEOMICS; CYTOLOGY; METABOLISM;

BONE DEVELOPMENT; CELL DIFFERENTIATION; HUMANS; MESENCHYMAL STEM CELLS; OSTEOBLASTS; PROTEOMICS;

EID: 37349030160     PISSN: None     EISSN: 14712164     Source Type: Journal    
DOI: 10.1186/1471-2164-8-380     Document Type: Article

References (48)

1. Le Blanc K Pittenger M Mesenchymal stem cells: Progress toward promise Cytotherapy 2005, 7(1):36-45 16040382
2. Barry FP Murphy JM Mesenchymal stem cells: Clinical applications and biological characterization Int J Biochem Cell Biol 2004, 36:568-584 15010324
3. Pittenger MF Mackay AM Beck SC Jaiswal RK Douglas R Mosca JD Moorman MA Simonetti DW Craig S Marshak DR Multilineage potential of adult human mesenchymal stem cells Science 1999, 284:143-147 10102814
4. Aubin JE Advances in the osteoblast lineage Biochem Cell Biol 1998, 76:899-910 10392704
5. Smith E Redman RA Logg CR Coetzee GA Kasahara N Frenkel B Glucocorticoids inhibit developmental stage-specific osteoblast cell cycle. Dissociation of cyclin A-cyclin-dependent kinase 2 from E2F4-p130 complexes J Biol Chem 2000, 275:19992-20001 10867026
6. Hou Z Nguyen Q Frenkel B Nilsson SK Milne M van Wijnen AJ Stein JL Quesenberry P Lian JB Stein GS Osteoblast-specific gene expression after transplantation of marrow cells: Implications for skeletal gene therapy Proc Natl Acad Sci USA 1999, 96:7294-7299 22079 10377408
7. Ryoo HM Hoffmann HM Beumer T Frenkel B Towler DA Stein GS Stein JL van Wijnen AJ Lian JB Stage-specific expression of Dlx-5 during osteoblast differentiation: Involvement in regulation of osteocalcin gene expression Mol Endocrinol 1997, 11:1681-1694 9328350
8. Song L Tuan RS Transdifferentiation potential of human mesenchymal stem cells derived from bone marrow FASEB J 2004, 18:980-982 15084518
9. Song L Webb NE Song Y Tuan RS Identification and functional analysis of candidate genes regulating mesenchymal stem cell self-renewal and multipotency Stem Cells 2006, 24:1707-1718 16574750
10. Engler AJ Sen S Sweeney HL Discher DE Matrix elasticity directs stem cell lineage specification Cell 2006, 126:677-689 16923388
11. Klees RF Salasznyk RM Kingsley K Williams WA Boskey A Plopper GE Laminin-5 induces osteogenic gene expression in human mesenchymal stem cells through an ERK dependent pathway Mol Biol Cell 2005, 16:881-890 545919 15574877
12. Salasznyk RM Klees RF Hughlock MK Plopper GE ERK signaling pathways regulate the osteogenic differentiation of human mesenchymal stem cells on collagen I and vitronectin Cell Commun Adhes 2004, 11:137-153 16194881
13. Salasznyk RM Williams WA Boskey A Batorsky A Plopper GE Adhesion to Vitronectin and Collagen I Promotes Osteogenic Differentiation of Human Mesenchymal Stem Cells J Biomed Biotechnol 2004, 2004:24-34 545655 15123885
14. Xiao G Gopalakrishnan R Jiang D Reith E Benson MD Franceschi RT Bone morphogenetic proteins, extracellular matrix, and mitogen-activated protein kinase signaling pathways are required for osteoblast-specific gene expression and differentiation in MC3T3-E1 cells J Bone Miner Res 2002, 17:101-110 11771655
15. Salasznyk RM Klees RF Vandenberg S Bennett K Plopper GE Gene focusing as a basis for controlling stem cell differentiation Stem Cells Dev 2005, 14:608-620 16433616
16. Klees RF Salasznyk RM Vandenberg S Bennett K Plopper GE Laminin-5 activates extracellular matrix production and osteogenic gene focusing in human mesenchymal stem cells Matrix Biol 2007, 26:106-114 1852504 17137774
17. Bortell R Barone LM Tassinari MS Lian JB Stein GS Gene expression during endochondral bone development: Evidence for coordinate expression of transforming growth factor beta 1 and collagen type I J Cell Biochem 1990, 44:81-91 2250045
18. Pace JM Chitayat D Atkinson M Wilcox WR Schwarze U Byers PH A single amino acid substitution (D1441Y) in the carboxyl-terminal propeptide of the proalpha1(I) chain of type I collagen results in a lethal variant of osteogenesis imperfecta with features of dense bone diseases J Med Genet 2002, 39:23-29 11826020
19. Aszodi A Bateman JF Gustafsson E Boot-Handford R Fassler R Mammalian skeletogenesis and extracellular matrix: What can we learn from knockout mice? Cell Struct Funct 2000, 25:73-84 10885577
20. Cool SM Nurcombe V Substrate induction of osteogenesis from marrow-derived mesenchymal precursors Stem Cells Dev 2005, 14:632-642 16433618
21. Mizuno M Kuboki Y Osteoblast-related gene expression of bone marrow cells during the osteoblastic differentiation induced by type I collagen J Biochem (Tokyo) 2001, 129:133-138 11134967
22. Xiao G Wang D Benson MD Karsenty G Franceschi RT Role of the alpha2-integrin in osteoblast-specific gene expression and activation of the Osf2 transcription factor J Biol Chem 1998, 273:32988-32994 9830051
23. Wall ME Rechtsteiner A Rocha LM Singular Value Decomposition and Principal Component Analysis A Practical Approach to Microarray Data Analysis Norwell MA: Kluwer Berrar DP, Dubitzky W, Granzow M 2003, 91-109
24. Tucker LR Some mathematical notes on three-mode factor analysis Psychometrika 1966, 31:279-311 5221127
25. Hayman MW Christie VB Keating TS Przyborski SA Following the differentiation of human pluripotent stem cells by proteomic identification of biomarkers Stem Cells Dev 2006, 15:221-231 16646668
26. Shi S Robey PG Gronthos S Comparison of human dental pulp and bone marrow stromal stem cells by cDNA microarray analysis Bone 2001, 29:532-539 11728923
27. Tremain N Korkko J Ibberson D Kopen GC DiGirolamo C Phinney DG MicroSAGE analysis of 2,353 expressed genes in a single cell-derived colony of undifferentiated human mesenchymal stem cells reveals mRNAs of multiple cell lineages Stem Cells 2001, 19:408-418 11553849
28. Jia L Young MF Powell J Yang L Ho NC Hotchkiss R Robey PG Francomano CA Gene expression profile of human bone marrow stromal cells: high-throughput expressed sequence tag sequencing analysis Genomics 2002, 79:7-17 11827452
29. Alter O Golub GH Reconstructing the pathways of a cellular system from genome-scale signals by using matrix and tensor computations Proc Natl Acad Sci USA 2005, 102:17559-17564 1308929 16314560
30. Fu CA Shen M Huang BC Lasaga J Payan DG Luo Y TNIK, a novel member of the germinal center kinase family that activates the c-Jun N-terminal kinase pathway and regulates the cytoskeleton J Biol Chem 1999, 274:30729-30737 10521462
31. Matsuda A Suzuki Y Honda G Muramatsu S Matsuzaki O Nagano Y Doi T Shimotohno K Harada T Nishida E Hayashi H Sugano S Large-scale identification and characterization of human genes that activate NF-kappaB and MAPK signaling pathways Oncogene 2003, 22:3307-3318 12761501
32. Salasznyk RM Westcott AM Klees RF Ward DF Xiang Z Vandenberg S Bennett K Plopper GE Comparing the protein expression profiles of human mesenchymal stem cells and human osteoblasts using gene ontologies Stem Cells Dev 2005, 14:354-366 16137224
33. Parker GC Anastassova-Kristeva M Eisenberg LM Rao MS Williams MA Sanberg PR English D Stem cells: Shibboleths of development, part II: Toward a functional definition Stem Cells Dev 2005, 14:463-469 16305331
34. Tang CH Yang RS Huang TH Liu SH Fu WM Enhancement of fibronectin fibrillogenesis and bone formation by basic fibroblast growth factor via protein kinase C-dependent pathway in rat osteoblasts Mol Pharmacol 2004, 66:440-449 15322235
35. Liang M Liao EY Xu X Luo XH Xiao XH Effects of progesterone and 18-methyl levonorgestrel on osteoblastic cells Endocr Res 2003, 29:483-501 14682477
36. Yuan J Murrell GA Trickett A Landtmeters M Knoops B Wang MX Overexpression of antioxidant enzyme peroxiredoxin 5 protects human tendon cells against apoptosis and loss of cellular function during oxidative stress Biochim Biophys Acta 2004, 1693:37-45 15276323
37. Kainulainen T Pender A D'Addario M Feng Y Lekic P McCulloch CA Cell death and mechanoprotection by filamin a in connective tissues after challenge by applied tensile forces J Biol Chem 2002, 277:21998-22009 11909861
38. Nakamura F Hartwig JH Stossel TP Szymanski PT Ca2+ and calmodulin regulate the binding of filamin A to actin filaments J Biol Chem 2005, 280:32426-32433 16030015
39. Tsutsumi S Yanagawa T Shimura T Fukumori T Hogan V Kuwano H Raz A Regulation of cell proliferation by autocrine motility factor/ phosphoglucose isomerase signaling J Biol Chem 2003, 278:32165-32172 12783864
40. Martins da Silva SJ Bayne RA Cambray N Hartley PS McNeilly AS Anderson RA Expression of activin subunits and receptors in the developing human ovary: Activin A promotes germ cell survival and proliferation before primordial follicle formation Dev Biol 2004, 266:334-345 14738881
41. Williams WA Schapiro NE Christy SR Weber GL Salasznyk RM Plopper GE Diminished Gene Expression in human Mesenchymal Stem Cells by Mutation of Focal Adhesion Kinase Signaling J Stem Cells 2006, 1:173-182
42. Entrez Gene http://www.ncbi.nih.gov/entrez/query.fcgi?db=gene
43. International Protein Index http://www.ebi.ac.uk/IPI/IPIhelp.html
44. International Protein Index Current Datasets ftp://ftp.ebi.ac.uk/pub/ databases/IPI/current/
45. Database for Annotation, Visualization and Integrated Discovery http://david.abcc.ncifcrf.gov/
46. De Lathauwer L De Moor B Vandewall JA A multilinear Singular Value Decomposition SIAM J Matrix Anal Appl 2000, 21:1253-1278
47. Eigenvector Research, PLS Toolbox http://software.eigenvector.com/#pls
48. Smilde AK Bro R Geladi P Multi-way Analysis with Applications in the Chemical Sciences Chichester, England: Wiley 2004