A comparative biochemical analysis of glycosaminoglycans and proteoglycans in human orthotopic and heterotopic bone

IUBMB Life

Volumn 61, Issue 4, 2009, Pages 447-452

  Mania, Vassiliki M ^a   Kallivokas, Alkiviadis G ^b   Malavaki, Christina ^a   Asimakopoulou, Athanasia P ^a   Kanakis, John ^a   Theocharis, Achilleas D ^a   Klironomos, George ^b   Gatzounis, George ^b   Mouzaki, Athanasia ^a   Panagiotopoulos, Elias ^b   Karamanos, Nikos K ^a  

^a UNIVERSITY OF PATRAS   (Greece)

^b UNIVERSITY HOSPITAL OF PATRAS   (Greece)

Author keywords

Ectopic bone; Glycosaminoglycans; Heterotopic ossification; Proteoglycans

Indexed keywords

AGGRECAN; CHONDROITIN SULFATE; DECORIN; DISACCHARIDE; GAG PROTEIN; GLYCOSAMINOGLYCAN; PROTEOGLYCAN;

ADULT; AGED; ARTICLE; BIOCHEMISTRY; BONE TISSUE; HUMAN; HUMAN TISSUE; MALE; PROTEIN ANALYSIS; PROTEIN STRUCTURE; BONE DEVELOPMENT; CHEMISTRY; COMPARATIVE STUDY; ELECTROPHORESIS; FEMUR; FRACTIONATION; HETEROTOPIC OSSIFICATION; IMMUNOHISTOCHEMISTRY; METABOLISM; PATHOPHYSIOLOGY; PHYSIOLOGY;

CHEMICAL FRACTIONATION; CHONDROITIN SULFATES; ELECTROPHORESIS, CELLULOSE ACETATE; FEMUR; GLYCOSAMINOGLYCANS; HUMANS; IMMUNOHISTOCHEMISTRY; OSSIFICATION, HETEROTOPIC; OSTEOGENESIS; PROTEOGLYCANS;

EID: 67650382098     PISSN: 15216543     EISSN: 15216551     Source Type: Journal    
DOI: 10.1002/iub.167     Document Type: Article

References (24)

1. McCarthy, E. F. and Sundaram, M. (2005) Heterotopic ossification: a review. Skeletal. Radiol. 34, 609-619.
2. Pape, H. C., Marsh, S., Morley, J. R., Krettek, C., and Giannoudis, P. V. (2004) Current concepts in the development of heterotopic ossification. J. Bone. Joint. Surg. Br. 86B: 783-787. (Pubitemid 39173460)
3. Waddington, R. J., Embery, G., and Last, K. S. (1989) Glycosaminoglycans of human alveolar bone. Arch. Oral. Biol. 34, 587-589.
4. Malavaki, C. J., Kanakis, I., Theocharis, A. D., Lamari, F. N., and Karamanos N. K. (2007) Hyaluronan determination: biological significance and analytical tools. Curr. Pharm. Anal. 3, 117-128.
5. Engfeldt, B. and Hjerpe, A. (1976) Glycosaminoglycans and proteoglycans of human bone tissue at different stages of mineralization. APMIS. 84, 95-106.
6. Smith, A. J., Singhrao, S. K., Newman, G. R., Waddington, R. J., and Embery, G. (1997) A biochemical and immuno-electron microscopical analysis of chondroitin sulphate-rich proteoglycans in human alveolar bone. Histochem. J. 29, 1-9.
7. Vynios, D. H., Karamanos, N. K., and Tsiganos, C. P. (2002) Advances in analysis of glycosaminoglycans: its application for the assessment of physiological states of connective tissues. J. Chromatogr. B. 781, 21-38.
8. Lamoureux, F., Baudhuin, M., Duplomb, L., Heymann, D., and Redini, F. (2007) Proteoglycans: key partners in bone cell biology. BioEssays. 29, 758-771.
9. Theocharis, A. D., Seidel, C., Borset, M., Dobra, K., Baykov, V., Labropoulou, V., Kanakis, I., Dalas, E., Karamanos, N. K., Sundan, A., and Hjerpe, A. (2006) Serglycin constitutively secreted by myeloma plasma cells is a potent inhibitor of bone mineralization in vitro. J. Biol. Chem. 281, 3511-35128.
10. Skandalis, S. S., Theocharis, A. D., Theocharis, D. A., Papadas, T., Vynios, D. H., and Papageorgakopoulou, N. (2004) Matrix proteoglycans are markedly affected in advanced laryngeal squamous cell carcinoma. Biochim. Biophys. Acta. 1689, 152-161.
11. Theocharis, A. D., Tsolakis, I., Tsegenidis, T., and Karamanos, N. K. (1999) Human abdominal aortic aneurysm is closely associated with compositional and specific structural modifications at the glycosaminoglycan level. Atherosclerosis. 145, 359-368. (Pubitemid 29359145)
12. Hata, R. and Nagai, T. (1972) A rapid and micro method for separation of acidic glycosaminoglycans by two-dimensional electrophoresis. Anal. Biochem. 45, 462.
13. Malavaki, C. J., Asimakopoulou, A. P., Lamari, F. N., Theoharis, A. D., Tzanakakis, G. N., and Karamanos, N. K. (2008) Capillary electrophoresis for the quality control of chondroitin sulfates in raw materials and formulations. Anal. Biochem. 374, 213-220.
14. Lamari, F. N., Militsopoulou, M., Mitropoulou, T. N., Hjerpe, A., and Karamanos, N. K. (2002) Analysis of glycosaminoglycan-derived disaccharides in biologic samples by capillary electrophoresis and protocol for sequencing glycosaminoglycans. Biomed. Chromatogr. 16, 95-102.
15. Karamanos, N. K., Axelsson, S., Vanky, P., Tzanakakis, G. N., and Hjerpe, A. (1995) Determination of hyaluronan and galactosaminoglycan disaccharides by high-performance capillary electrophoresis at the attomole level. Applications to analyses of tissue and cell culture proteoglycans. J. Chromatogr. A., 696, 295-305.
16. Laemmli, U. K. (1970) Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature. 227, 680-685.
17. Claassen, H., Cellarius, C., Scholz-Ahrens, K. E., Schrezenmeir, J., Glüer, C. C., Schünke, M., and Kurz, B. (2006) Extracellular matrix changes in knee joint cartilage following bone-active drug treatment. Cell. Tissue. Res. 324, 279-289.
18. Simonaro, C. M., Angelo, M. D., He, X., Eliyahu, E., Shraizent, N., Haskins, M. E., and Schuchman, E. H. (2008) Mechanism of glycosaminoglycan- mediated bone and joint disease. Implications for the mucopolysaccharidoses and other connective tissue diseases. Am. J. Pathol. 172, 112-122.
19. Prince, C. W., Rahemtulla, F., and Butler, W. T. (1983) Metabolism of rat bone proteoglycans in vivo. Biochem. J. 216, 589-596. (Pubitemid 14205972)
20. Fisher, L. W. (1984) The nature of the proteoglycans of bone. In Chemistry and Biology of Mineralised Tissues, 2nd International Conference on the Chemistry and Biology of Mineralised Tissues. (Buttler, W. T., ed.). pp. 188-196, Ebsco Media, Birmingham, Alabama.
21. Takeuchi, Y., Kodama, Y., and Matsumoto, T. (1994) Bone matrix decorin binds transforming growthfactor-beta and enhances its bioactivity. J. Biol. Chem. 269, 32634-32638.
22. Hausser, H., Groning, A., Hasilik, A., Schonherr, E., and Kresse, H. (1994) Selective inactivity of TGF-beta/decorin complexes. FEBS. Lett. 353, 243-245.
23. Markmann, A., Hausser, H., Schonherr, E., and Kresse, H. (2000) Influence of decorin expression on transforming growth factor -beta-mediated collagen gel retraction and biglycan induction. Matrix. Biol. 19, 631-636.
24. Bi, Y., Stuelten, C. H., Kilts, T., Wadhwa, S., Iozzo, R. V., Robey, P. G., Chen, X.-D., and Young, M. F. (2005) Extracellular matrix proteoglycans control the fate of bone marrow stromal cells. J. Biol. Chem. 280, 30481-30489.