Blockade of Kv1.3 Potassium Channels Inhibits Differentiation and Granzyme B Secretion of Human CD8+ T Effector Memory Lymphocytes

PLoS ONE

Volumn 8, Issue 1, 2013, Pages

  Hu, Lina ^a   Wang, Tongguang ^b   Gocke, Anne R ^a   Nath, Avindra ^b   Zhang, Hao ^c   Margolick, Joseph B ^c   Whartenby, Katharine A ^a   Calabresi, Peter A ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE   (United States)

^c JOHNS HOPKINS BLOOMBERG SCHOOL OF PUBLIC HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GRANZYME B; POTASSIUM CHANNEL KV1.3;

ARTICLE; AUTOIMMUNE DISEASE; CD8+ T LYMPHOCYTE; CONTROLLED STUDY; CYTOTOXICITY; ENZYME RELEASE; ENZYME SYNTHESIS; FETUS; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE TEST; LYMPHOCYTE DIFFERENTIATION; LYMPHOCYTE PROLIFERATION; MOLECULAR PATHOLOGY; MULTIPLE SCLEROSIS; NERVE CELL; PROTEIN EXPRESSION; PROTEIN FUNCTION; T LYMPHOCYTE ACTIVATION;

CD8-POSITIVE T-LYMPHOCYTES; CELL DIFFERENTIATION; CELL PROLIFERATION; GRANZYMES; HUMANS; IMMUNOLOGIC MEMORY; KV1.3 POTASSIUM CHANNEL; LYMPHOCYTE ACTIVATION; POTASSIUM CHANNEL BLOCKERS;

EID: 84873842925     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0054267     Document Type: Article

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