Essential role of class II phosphatidylinositol-3-kinase-c2α in sphingosine 1-phosphate receptor-1-mediated signaling and migration in endothelial cells

Journal of Biological Chemistry

Volumn 288, Issue 4, 2013, Pages 2325-2339

  Biswas, Kuntal ^a   Yoshioka, Kazuaki ^a   Asanuma, Ken ^b   Okamoto, Yasuo ^a   Takuwa, Noriko ^a,c   Sasaki, Takehiko ^b   Takuwa, Yoh ^a  

^a KANAZAWA UNIVERSITY   (Japan)

^b AKITA UNIVERSITY   (Japan)

^c ISHIKAWA PREFECTURAL NURSING UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATION ANALYSIS; ALKANOLAMINES; CELL MEMBRANES; CELL PROLIFERATION; CHEMICAL ACTIVATION; CYTOLOGY; ENDOTHELIAL CELLS; MOLECULAR BIOLOGY; PHOSPHOLIPIDS; SPHINGOSINES;

G PROTEIN COUPLED RECEPTORS; PHARMACOLOGICAL INHIBITION; PHOSPHATIDYLINOSITOL; PHOSPHOINOSITIDES; SIGNALING MOLECULES; SPHINGOSINE 1 PHOSPHATES; VASCULAR FUNCTIONS; VESICULAR TRAFFICKING;

CELL SIGNALING;

BETA ACTIN; CLASS II PHOSPHATIDYLINOSITOL 3 KINASE C2ALPHA; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHATIDYLINOSITOL 3 PHOSPHATE; PROTEIN KINASE B; PROTEIN P110; PROTEIN P110ALPHA; PROTEIN P110BETA; RAC1 PROTEIN; REGULATOR PROTEIN; SPHINGOSINE 1 PHOSPHATE; SPHINGOSINE 1 PHOSPHATE RECEPTOR; SPHINGOSINE 1 PHOSPHATE RECEPTOR 1; UNCLASSIFIED DRUG;

ACTIN FILAMENT; ARTICLE; BETA ACTIN GENE; CELL COMPARTMENTALIZATION; CELL MIGRATION; CELL STIMULATION; CELL TRANSFORMATION; CONTROLLED STUDY; ENDOCYTOSIS; ENDOSOME; ENDOTHELIUM CELL; ENZYME ACTIVATION; GENE EXPRESSION REGULATION; GENE SILENCING; HUMAN; HUMAN CELL; INTERNALIZATION; INTRACELLULAR SIGNALING; LAMELLIPODIUM; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN TARGETING; SPHINGOSINE 1 PHOSPHATE RECEPTOR GENE;

EID: 84873802942     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.409656     Document Type: Article

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