Tryptophan at the transmembrane-cytosolic junction modulates thrombopoietin receptor dimerization and activation

Proceedings of the National Academy of Sciences of the United States of America

Volumn 110, Issue 7, 2013, Pages 2540-2545

  Defour, Jean Philippe ^a   Itaya, Miki ^b   Gryshkova, Vitalina ^a   Brett, Ian C ^b   Pecquet, Christian ^a   Sato, Takeshi ^c   Smith, Steven O ^b   Constantinescu, Stefan N ^a  

^a UNIVERSITÉ CATHOLIQUE DE LOUVAIN   (Belgium)

^b STONY BROOK UNIVERSITY   (United States)

^c OSAKA UNIVERSITY   (Japan)

Author keywords

FTIR spectroscopy; JAK2; Myeloproliferation; NMR spectroscopy; Transmembrane domain

Indexed keywords

THROMBOPOIETIN RECEPTOR; TRYPTOPHAN;

ARTICLE; CONTROLLED STUDY; DIMERIZATION; INFRARED SPECTROSCOPY; JUXTAGLOMERULAR APPARATUS; MUTAGENESIS; MYELOPROLIFERATIVE NEOPLASM; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

AMINO ACID MOTIFS; ANIMALS; BASE SEQUENCE; BLOTTING, WESTERN; CELL LINE; CLONING, MOLECULAR; DIMERIZATION; FLOW CYTOMETRY; GENETIC COMPLEMENTATION TEST; HUMANS; LUCIFERASES; MAGNETIC RESONANCE SPECTROSCOPY; MICE; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; PROTEIN CONFORMATION; RECEPTORS, THROMBOPOIETIN; SEQUENCE ANALYSIS, DNA; SPECTROPHOTOMETRY, INFRARED; TRYPTOPHAN; ULTRACENTRIFUGATION;

EID: 84873726286     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1211560110     Document Type: Article

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