PGRN is a key adipokine mediating high fat diet-induced insulin resistance and obesity through IL-6 in adipose tissue

Cell Metabolism

Volumn 15, Issue 1, 2012, Pages 38-50

  Matsubara, Toshiya ^a,c,f   Mita, Ayako ^a,b   Minami, Kohtaro ^a   Hosooka, Tetsuya ^b   Kitazawa, Sohei ^d,j   Takahashi, Kenichi ⁱ   Tamori, Yoshikazu ^b,g   Yokoi, Norihide ^a   Watanabe, Makoto ^f,h   Matsuo, Ei Ichi ^f,h   Nishimura, Osamu ^c,h   Seino, Susumu ^a,b,c,e  

^a Division of Cellular and Molecular Medicine   (Japan)

^b Division of Diabetes and Endocrinology   (Japan)

^c Integrated Center for Mass Spectrometry   (Japan)

^d KOBE UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^e JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

^f SHIMADZU CORPORATION   (Japan)

^g Chibune Hospital   (Japan)

^h OSAKA UNIVERSITY   (Japan)

ⁱ JCR Pharmaceuticals Co Ltd   (Japan)

^j EHIME UNIVERSITY SCHOOL OF MEDICINE   (Japan)

more..

Author keywords

[No Author keywords available]

Indexed keywords

DEXAMETHASONE; INTERLEUKIN 6; PIOGLITAZONE; PROGRANULIN; SUPPRESSOR OF CYTOKINE SIGNALING 3; TUMOR NECROSIS FACTOR ALPHA;

ADIPOCYTE; ADIPOSE TISSUE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CYTOKINE RELEASE; DRUG TARGETING; IMMUNOHISTOCHEMISTRY; INSULIN RESISTANCE; LIPID DIET; MALE; MOUSE; NONHUMAN; OBESITY; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION;

3T3-L1 CELLS; ADIPOKINES; ADIPOSE TISSUE; ANIMALS; DEXAMETHASONE; DIET, HIGH-FAT; INSULIN RESISTANCE; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; INTERLEUKIN-6; MALE; MICE; MICE, INBRED C57BL; MICE, OBESE; OBESITY; RECOMBINANT PROTEINS; THIAZOLIDINEDIONES; TUMOR NECROSIS FACTOR-ALPHA;

MUS;

EID: 84855430348     PISSN: 15504131     EISSN: 19327420     Source Type: Journal    
DOI: 10.1016/j.cmet.2011.12.002     Document Type: Article

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