Runx2 protein stabilizes hypoxia-inducible factor-1α through competition with von Hippel-Lindau protein (pVHL) and stimulates angiogenesis in growth plate hypertrophic chondrocytes

Journal of Biological Chemistry

Volumn 287, Issue 18, 2012, Pages 14760-14771

  Lee, Sun Hee ^a   Che, Xiangguo ^c   Jeong, Jae Hwan ^c   Choi, Je Yong ^c   Lee, Young Joo ^d   Lee, Yong Hee ^e   Bae, Suk Chul ^e   Lee, You Mie ^a,b  

^a Kyungpook National University   (South Korea)

^b Research Institute of Pharmaceutical Sciences   (South Korea)

^c Kyungpook National University School of Medicine   (South Korea)

^d Sejong University   (South Korea)

^e Chungbuk National University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

CELL ENGINEERING; ENDOTHELIAL CELLS; MAMMALS; TRANSCRIPTION;

HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HYPERTROPHIC CHONDROCYTES; HYPOXIA INDUCIBLE FACTOR-1 ALPHA; NORMOXIC CONDITIONS; NUCLEAR TRANSLOCATIONS; VASCULAR ENDOTHELIAL GROWTH FACTOR; VON HIPPEL LINDAU; VON HIPPEL-LINDAU TUMOR SUPPRESSOR PROTEINS;

PROTEINS;

CD31 ANTIGEN; HYPOXIA INDUCIBLE FACTOR 1ALPHA; TRANSCRIPTION FACTOR RUNX2; VASCULOTROPIN; VON HIPPEL LINDAU PROTEIN;

ACETYLATION; ANGIOGENESIS; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BONE DEVELOPMENT; CARTILAGE CELL; CELL NUCLEUS TRANSPLANTATION; CONTROLLED STUDY; EMBRYO; ENCHONDRAL OSSIFICATION; GROWTH PLATE; HUMAN; HUMAN CELL; HYDROXYLATION; HYPERTROPHY; IMMUNOHISTOCHEMISTRY; MOLECULAR INTERACTION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; PROTEIN SECRETION; PROTEIN STABILITY; PROTEIN SYNTHESIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TRANSCRIPTION INITIATION; UBIQUITINATION; UMBILICAL VEIN; WESTERN BLOTTING;

MUS;

EID: 84860385177     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.340232     Document Type: Article

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