Autophagy-dependent EIF2AK3 activation compromises ursolic acid-induced apoptosis through upregulation of MCL1 in MCF-7 human breast cancer cells

Autophagy

Volumn 9, Issue 2, 2013, Pages 196-207

  Zhao, Chong ^a   Yin, Shutao ^a   Dong, Yinhui ^a   Guo, Xiao ^a   Fan, Lihong ^a   Ye, Min ^b   Hu, Hongbo ^a  

^a CHINA AGRICULTURAL UNIVERSITY   (China)

^b PEKING UNIVERSITY HEALTH SCIENCE CENTER   (China)

Author keywords

Apoptosis; Autophagy; Cytoprotection; EIF2AK3; ER stress; MCF 7; MCL1; Ursolic acid

Indexed keywords

EIF2AK3 PROTEIN; MAMMALIAN TARGET OF RAPAMYCIN; MEMBRANE PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PROTEIN MCL 1; UNCLASSIFIED DRUG; URSOLIC ACID;

ANTINEOPLASTIC ACTIVITY; ARTICLE; AUTOPHAGY; BREAST CANCER; CELL STRAIN MCF 7; ENDOPLASMIC RETICULUM; ENDOPLASMIC RETICULUM STRESS; ENZYME ACTIVATION; ENZYME INHIBITION; HUMAN; HUMAN CELL; UPREGULATION;

EID: 84873658604     PISSN: 15548627     EISSN: 15548635     Source Type: Journal    
DOI: 10.4161/auto.22805     Document Type: Article

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