A combination of indol-3-carbinol and genistein synergistically induces apoptosis in human colon cancer HT-29 cells by inhibiting Akt phosphorylation and progression of autophagy

Molecular Cancer

Volumn 8, Issue , 2009, Pages

  Nakamura, Yoshitaka ^a,b   Yogosawa, Shingo ^a   Izutani, Yasuyuki ^a   Watanabe, Hirotsuna ^a   Otsuji, Eigo ^b   Sakai, Tosiyuki ^a  

^a KYOTO PREFECTURAL UNIVERSITY OF MEDICINE   (Japan)

^b KYOTO PREFECTURAL UNIVERSITY OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; BETA ACTIN; CASPASE 3; CASPASE 8; CASPASE 9; GENISTEIN; INDOL 3 CARBINOL; UNCLASSIFIED DRUG; 3 INDOLEMETHANOL; 3 METHYLADENINE; 3-METHYLADENINE; ADENINE; DRUG DERIVATIVE; INDOLE DERIVATIVE; INDOLE-3-CARBINOL; PROTEIN KINASE B;

APOPTOSIS; ARTICLE; AUTOPHAGY; CANCER CELL; CELL MATURATION; CELL STRAIN HT29; CELL VIABILITY; COLON CANCER; CONTROLLED STUDY; DOWN REGULATION; DRUG POTENTIATION; ENZYME ACTIVITY; FLOW CYTOMETRY; HUMAN; HUMAN CELL; PHAGOSOME; PHYTOCHEMISTRY; PROTEIN DEPHOSPHORYLATION; PROTEIN PHOSPHORYLATION; CELL SURVIVAL; COLON TUMOR; DRUG ANTAGONISM; DRUG EFFECT; DRUG SCREENING; ENZYMOLOGY; METABOLISM; PATHOLOGY; PHOSPHORYLATION;

ADENINE; APOPTOSIS; AUTOPHAGY; CELL SURVIVAL; COLONIC NEOPLASMS; DRUG SCREENING ASSAYS, ANTITUMOR; DRUG SYNERGISM; GENISTEIN; HT29 CELLS; HUMANS; INDOLES; PHAGOSOMES; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-AKT;

EID: 71049121968     PISSN: None     EISSN: 14764598     Source Type: Journal    
DOI: 10.1186/1476-4598-8-100     Document Type: Article

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