Dimerization of Sir3 via its C-terminal winged helix domain is essential for yeast heterochromatin formation

EMBO Journal

Volumn 32, Issue 3, 2013, Pages 437-449

  Oppikofer, Mariano ^a,b   Kueng, Stephanie ^a   Keusch, Jeremy J ^a   Hassler, Markus ^c   Ladurner, Andreas G ^c   Gut, Heinz ^a   Gasser, Susan M ^a,b  

^a FRIEDRICH MIESCHER INSTITUTE FOR BIOMEDICAL RESEARCH   (Switzerland)

^b UNIVERSITY OF BASEL   (Switzerland)

^c UNIVERSITY OF MUNICH   (Germany)

Author keywords

Dimerization; Heterochromatin; Orc1; Sir3; Winged helix turn helix

Indexed keywords

HELIX LOOP HELIX PROTEIN; HOMODIMER; SILENT INFORMATION REGULATOR PROTEIN; SILENT INFORMATION REGULATOR PROTEIN 3; UNCLASSIFIED DRUG;

ALPHA HELIX; ARTICLE; BETA SHEET; BINDING AFFINITY; CARBOXY TERMINAL SEQUENCE; CRYSTAL STRUCTURE; DIMERIZATION; GENE DELETION; GENE DUPLICATION; GENE LOCUS; GENE OVEREXPRESSION; GENE REPRESSION; GENE SILENCING; HETEROCHROMATIN; IN VITRO STUDY; IN VIVO STUDY; NONHUMAN; NUCLEOSOME; PRIORITY JOURNAL; PROTEIN DNA BINDING; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN MOTIF; PROTEIN STRUCTURE; SACCHAROMYCES CEREVISIAE; SITE DIRECTED MUTAGENESIS; TELOMERE; X RAY CRYSTALLOGRAPHY;

AMINO ACID SEQUENCE; CHROMATIN; CHROMATIN IMMUNOPRECIPITATION; CRYSTALLIZATION; DIMERIZATION; DNA PRIMERS; EVOLUTION, MOLECULAR; GENE SILENCING; GENETIC COMPLEMENTATION TEST; HETEROCHROMATIN; IMMUNOPRECIPITATION; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTAGENESIS; NUCLEOSOMES; POLYMERASE CHAIN REACTION; PROTEIN CONFORMATION; SACCHAROMYCES CEREVISIAE; SEQUENCE ALIGNMENT; SILENT INFORMATION REGULATOR PROTEINS, SACCHAROMYCES CEREVISIAE;

ARCHAEA; BACTERIA (MICROORGANISMS); SACCHAROMYCETALES;

EID: 84873567117     PISSN: 02614189     EISSN: 14602075     Source Type: Journal    
DOI: 10.1038/emboj.2012.343     Document Type: Article

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