메뉴 건너뛰기




Volumn 18, Issue 10, 1998, Pages 6110-6120

Functional characterization of the N terminus of Sir3p

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; CHROMATIN STRUCTURE; CONTROLLED STUDY; GENE EXPRESSION REGULATION; GENE OVEREXPRESSION; GENE REPRESSION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DNA INTERACTION; PROTEIN DOMAIN; REPORTER GENE; SACCHAROMYCES CEREVISIAE;

EID: 0031682736     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.18.10.6110     Document Type: Article
Times cited : (39)

References (52)
  • 1
    • 0025900189 scopus 로고
    • Modifiers of position effect are shared between telomeric and silent mating-type loci in S. cerevisiae
    • Aparicio, O. M., B. L. Billington, and D. E. Gottschling. 1991. Modifiers of position effect are shared between telomeric and silent mating-type loci in S. cerevisiae Cell 66:1279-1287.
    • (1991) Cell , vol.66 , pp. 1279-1287
    • Aparicio, O.M.1    Billington, B.L.2    Gottschling, D.E.3
  • 2
    • 0028832366 scopus 로고
    • The multidomain structure of Orc1p reveals similarity to regulators of DNA replication and transcriptional silencing
    • Bell, S. P., J. Mitchell, J. Leber, R. Kobayashi, and B. Stillman. 1995. The multidomain structure of Orc1p reveals similarity to regulators of DNA replication and transcriptional silencing. Cell 83:563-568.
    • (1995) Cell , vol.83 , pp. 563-568
    • Bell, S.P.1    Mitchell, J.2    Leber, J.3    Kobayashi, R.4    Stillman, B.5
  • 3
    • 0023484186 scopus 로고
    • 5-Fluoroorotic acid as a selective agent in yeast molecular genetics
    • Boeke, J. D., J. Trueheart, G. Natsoulis, and G. R. Fink. 1987. 5-Fluoroorotic acid as a selective agent in yeast molecular genetics. Methods Enzymol. 154: 164-175.
    • (1987) Methods Enzymol. , vol.154 , pp. 164-175
    • Boeke, J.D.1    Trueheart, J.2    Natsoulis, G.3    Fink, G.R.4
  • 5
    • 0028941966 scopus 로고
    • Action of a RAP1 carboxy-terminal silencing domain reveals an underlying competition between HMR and telomeres in yeast
    • Buck, S. W., and D. Shore. 1995. Action of a RAP1 carboxy-terminal silencing domain reveals an underlying competition between HMR and telomeres in yeast. Genes Dev. 9:370-384.
    • (1995) Genes Dev. , vol.9 , pp. 370-384
    • Buck, S.W.1    Shore, D.2
  • 7
    • 0029048189 scopus 로고
    • The carboxy termini of Sir4 and Rap1 affect Sir3 localization: Evidence for a multicomponent complex required for yeast telomeric silencing
    • Cockell, M., F. Palladino, T. Laroche, G. Kyrion, C. Liu, A. J. Lustig, and S. M. Gasser. 1995. The carboxy termini of Sir4 and Rap1 affect Sir3 localization: evidence for a multicomponent complex required for yeast telomeric silencing. J. Cell Biol. 129:909-924.
    • (1995) J. Cell Biol. , vol.129 , pp. 909-924
    • Cockell, M.1    Palladino, F.2    Laroche, T.3    Kyrion, G.4    Liu, C.5    Lustig, A.J.6    Gasser, S.M.7
  • 8
    • 0030831573 scopus 로고    scopus 로고
    • Direct evidence for SIR2 modulation of chromatin structure in yeast rDNA
    • Fritze, C. E., K. Verschueren, R. Strich, and R. E. Esposito. 1997. Direct evidence for SIR2 modulation of chromatin structure in yeast rDNA. EMBO J. 16:6495-6509.
    • (1997) EMBO J. , vol.16 , pp. 6495-6509
    • Fritze, C.E.1    Verschueren, K.2    Strich, R.3    Esposito, R.E.4
  • 9
    • 0029820640 scopus 로고    scopus 로고
    • The clustering of telomeres and colocalization with Rap1, Sir3 and Sir4 proteins in wild-type Saccharomyces cerevisiae
    • Gotta, M., T. Laroche, A. Formenton, L. Maillet, H. Scherthan, and S. M. Gasser. 1996. The clustering of telomeres and colocalization with Rap1, Sir3 and Sir4 proteins in wild-type Saccharomyces cerevisiae. J. Cell Biol. 134: 1349-1363.
    • (1996) J. Cell Biol. , vol.134 , pp. 1349-1363
    • Gotta, M.1    Laroche, T.2    Formenton, A.3    Maillet, L.4    Scherthan, H.5    Gasser, S.M.6
  • 11
    • 0024536650 scopus 로고
    • A new role for a yeast transcriptional silencer gene, SIR2, in regulation of recombination in ribosomal DNA
    • Gottlieb, S., and R. E. Esposito. 1989. A new role for a yeast transcriptional silencer gene, SIR2, in regulation of recombination in ribosomal DNA. Cell 56:771-776.
    • (1989) Cell , vol.56 , pp. 771-776
    • Gottlieb, S.1    Esposito, R.E.2
  • 12
    • 0025201982 scopus 로고
    • Position effect at S. cerevisiae telomeres: Reversible repression of Pol II transcription
    • Gottschling, D. E., O. M. Aparicio, B. L. Billington, and V. A. Zakian. 1990. Position effect at S. cerevisiae telomeres: reversible repression of Pol II transcription. Cell 63:751-762.
    • (1990) Cell , vol.63 , pp. 751-762
    • Gottschling, D.E.1    Aparicio, O.M.2    Billington, B.L.3    Zakian, V.A.4
  • 13
    • 85038545905 scopus 로고    scopus 로고
    • Personal communication
    • 12a.Grunstein, M. Personal communication.
    • Grunstein, M.1
  • 14
    • 0028174255 scopus 로고
    • Chromosome condensation and sister chromatid pairing in budding yeast
    • Guacci, V., E. Hogan, and D. Koshland. 1994. Chromosome condensation and sister chromatid pairing in budding yeast. J. Cell Biol. 125:517-530.
    • (1994) J. Cell Biol. , vol.125 , pp. 517-530
    • Guacci, V.1    Hogan, E.2    Koshland, D.3
  • 15
    • 0026623241 scopus 로고
    • A RAP1-interacting protein involved in transcriptional silencing and telomere length regulation
    • Hardy, C. F., L. Sussel, and D. Shore. 1992. A RAP1-interacting protein involved in transcriptional silencing and telomere length regulation. Genes Dev. 6:801-814.
    • (1992) Genes Dev. , vol.6 , pp. 801-814
    • Hardy, C.F.1    Sussel, L.2    Shore, D.3
  • 16
    • 0028919756 scopus 로고
    • Histone H3 and H4 N-termini interact with SIR3 and SIR4 proteins: A molecular model for the formation of heterochromatin in yeast
    • Hecht, A., T. Laroche, S. Strahl-Bolsinger, S. M. Gasser, and M. Grunstein. 1995. Histone H3 and H4 N-termini interact with SIR3 and SIR4 proteins: a molecular model for the formation of heterochromatin in yeast. Cell 80: 583-592.
    • (1995) Cell , vol.80 , pp. 583-592
    • Hecht, A.1    Laroche, T.2    Strahl-Bolsinger, S.3    Gasser, S.M.4    Grunstein, M.5
  • 17
    • 0029817763 scopus 로고    scopus 로고
    • Spreading of transcriptional represser SIR3 from telomeric heterochromatin
    • Hecht, A., S. Strahl-Bolsinger, and M. Grunstein. 1996. Spreading of transcriptional represser SIR3 from telomeric heterochromatin. Nature 383:92-96.
    • (1996) Nature , vol.383 , pp. 92-96
    • Hecht, A.1    Strahl-Bolsinger, S.2    Grunstein, M.3
  • 18
    • 0022625954 scopus 로고
    • Cloning and characterization of four SIR genes of Saccharomyces cerevisiae
    • Ivy, J. M., A. J. S. Klar, and J. B. Hicks. 1986. Cloning and characterization of four SIR genes of Saccharomyces cerevisiae. Mol. Cell. Biol. 6:688-702.
    • (1986) Mol. Cell. Biol. , vol.6 , pp. 688-702
    • Ivy, J.M.1    Klar, A.J.S.2    Hicks, J.B.3
  • 19
    • 0025002966 scopus 로고
    • Genetic evidence for an interaction between SIR3 and histone H4 in the repression of the silent mating loci in Saccharomyces cerevisiae
    • Johnson, L. M., P. S. Kayne, E. S. Kahn, and M. Grunstein. 1990. Genetic evidence for an interaction between SIR3 and histone H4 in the repression of the silent mating loci in Saccharomyces cerevisiae. Proc. Natl. Acad. Sci. USA 87:6286-6290.
    • (1990) Proc. Natl. Acad. Sci. USA , vol.87 , pp. 6286-6290
    • Johnson, L.M.1    Kayne, P.S.2    Kahn, E.S.3    Grunstein, M.4
  • 20
    • 0028829468 scopus 로고
    • Binding sites for abundant nuclear factors modulate RNA polymerase I-dependent enhancer function in Saccharomyces cerevisiae
    • Kang, J. J., T. J. Yokoi, and M. J. Holland. 1995. Binding sites for abundant nuclear factors modulate RNA polymerase I-dependent enhancer function in Saccharomyces cerevisiae. J. Biol. Chem. 270:28723-28732.
    • (1995) J. Biol. Chem. , vol.270 , pp. 28723-28732
    • Kang, J.J.1    Yokoi, T.J.2    Holland, M.J.3
  • 21
    • 0028210480 scopus 로고
    • Position-effect variegation and the new biology of heterochromatin
    • Karpen, G. H. 1994. Position-effect variegation and the new biology of heterochromatin. Curr. Opin. Genet. Dev. 4:281-291.
    • (1994) Curr. Opin. Genet. Dev. , vol.4 , pp. 281-291
    • Karpen, G.H.1
  • 22
    • 0024280881 scopus 로고
    • Extremely conserved histone H4 N terminus is dispensable for growth but essential for repressing the silent mating loci in yeast
    • Kayne, P. S., U. J. Kim, M. Han, J. R. Mullen, F. Yoshizaki, and M. Grunstein. 1988. Extremely conserved histone H4 N terminus is dispensable for growth but essential for repressing the silent mating loci in yeast. Cell 55: 27-39.
    • (1988) Cell , vol.55 , pp. 27-39
    • Kayne, P.S.1    Kim, U.J.2    Han, M.3    Mullen, J.R.4    Yoshizaki, F.5    Grunstein, M.6
  • 23
    • 0030916153 scopus 로고    scopus 로고
    • Redistribution of silencing proteins from telomeres to the nucleolus is associated with extension in life span in S. cerevisiae
    • Kennedy, B. K., M. Gotta, D. A. Sinclair, K. Mills, D. S. MeNabb, M. Murthy, S. M. Pak, T. Laroche, S. M. Gasser, and L. Guarente. 1997. Redistribution of silencing proteins from telomeres to the nucleolus is associated with extension in life span in S. cerevisiae. Cell 89:381-391.
    • (1997) Cell , vol.89 , pp. 381-391
    • Kennedy, B.K.1    Gotta, M.2    Sinclair, D.A.3    Mills, K.4    Menabb, D.S.5    Murthy, M.6    Pak, S.M.7    Laroche, T.8    Gasser, S.M.9    Guarente, L.10
  • 24
    • 0027326367 scopus 로고
    • RAP1 and telomere structure regulate telomere position effects in Saccharomyces cerevisiae
    • Kyrion, G., K. Liu, C. Liu, and A. J. Lustig. 1993. RAP1 and telomere structure regulate telomere position effects in Saccharomyces cerevisiae. Genes Dev. 7:1146-1159.
    • (1993) Genes Dev. , vol.7 , pp. 1146-1159
    • Kyrion, G.1    Liu, K.2    Liu, C.3    Lustig, A.J.4
  • 25
    • 0030009208 scopus 로고    scopus 로고
    • Genetic analysis of Rap1p/Sir3p interactions in telomeric and HML silencina in Saccharomyces cerevisiae
    • Liu, C., and A. J. Lustig. 1996. Genetic analysis of Rap1p/Sir3p interactions in telomeric and HML silencina in Saccharomyces cerevisiae. Genetics 143: 81-93.
    • (1996) Genetics , vol.143 , pp. 81-93
    • Liu, C.1    Lustig, A.J.2
  • 26
    • 0028138890 scopus 로고
    • Mutational analysis defines a C-terminal tail domain of RAP1 essential for telomeric silencing in Saccharomyces cerevisiae
    • Liu, C., X. Mao, and A. J. Lustig. 1994. Mutational analysis defines a C-terminal tail domain of RAP1 essential for telomeric silencing in Saccharomyces cerevisiae. Genetics 138:1025-1040.
    • (1994) Genetics , vol.138 , pp. 1025-1040
    • Liu, C.1    Mao, X.2    Lustig, A.J.3
  • 27
    • 0029746494 scopus 로고    scopus 로고
    • Evidence for silencing compartments within the yeast nucleus: A role for telomere proximity and Sir protein concentration in silencer-mediated repression
    • Maillet, L., C. Boscheron, M. Gotta, S. Marcand, E. Gilson, and S. M. Gasser. 1996. Evidence for silencing compartments within the yeast nucleus: a role for telomere proximity and Sir protein concentration in silencer-mediated repression. Genes Dev. 10:1796-1811.
    • (1996) Genes Dev. , vol.10 , pp. 1796-1811
    • Maillet, L.1    Boscheron, C.2    Gotta, M.3    Marcand, S.4    Gilson, E.5    Gasser, S.M.6
  • 28
    • 0023515404 scopus 로고
    • Functional domains of SIR4, a gene required for position effect regulation in Saccharomyces cerevisiae
    • Marshall, M., D. Mahoney, A. Rose, J. B. Hicks, and J. R. Broach. 1987. Functional domains of SIR4, a gene required for position effect regulation in Saccharomyces cerevisiae. Mol. Cell. Biol. 7:4441-4452.
    • (1987) Mol. Cell. Biol. , vol.7 , pp. 4441-4452
    • Marshall, M.1    Mahoney, D.2    Rose, A.3    Hicks, J.B.4    Broach, J.R.5
  • 29
    • 0030951007 scopus 로고    scopus 로고
    • Silent information regulator protein complexes in Saccharomyces cerevisiae: A SIR2/SIR4 complex and evidence for a regulatory domain in SIR4 that inhibits its interaction with SIR3
    • Moazed, D., A. kistler, A. Axelrod, J. Rine, and A. D. Johnson. 1997. Silent information regulator protein complexes in Saccharomyces cerevisiae: a SIR2/SIR4 complex and evidence for a regulatory domain in SIR4 that inhibits its interaction with SIR3. Proc. Natl. Acad. Sci. USA 94:2186-2191.
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 2186-2191
    • Moazed, D.1    Kistler, A.2    Axelrod, A.3    Rine, J.4    Johnson, A.D.5
  • 30
    • 0028004378 scopus 로고
    • Evidence that a complex of SIR proteins interacts with the silencer and telomere-binding protein RAP1
    • Moretti, P., K. Freeman, L. Coodly, and D. Shore. 1994. Evidence that a complex of SIR proteins interacts with the silencer and telomere-binding protein RAP1. Genes Dev. 8:2257-2269.
    • (1994) Genes Dev. , vol.8 , pp. 2257-2269
    • Moretti, P.1    Freeman, K.2    Coodly, L.3    Shore, D.4
  • 31
    • 0028953840 scopus 로고
    • Yeast vectors for the controlled expression of heterologous proteins in different genetic backgrounds
    • Mumberg, D., R. Muller, and M. Funk. 1995. Yeast vectors for the controlled expression of heterologous proteins in different genetic backgrounds. Gene 156:119-122.
    • (1995) Gene , vol.156 , pp. 119-122
    • Mumberg, D.1    Muller, R.2    Funk, M.3
  • 32
    • 0027423154 scopus 로고
    • SIR3 and SIR4 proteins are required for the positioning and integrity of yeast telomeres
    • Palladino, F., T. Laroche, E. Gilson, A. Axelrod, L. Pillus, and S. M. Gasser. 1993. SIR3 and SIR4 proteins are required for the positioning and integrity of yeast telomeres. Cell 75:543-555.
    • (1993) Cell , vol.75 , pp. 543-555
    • Palladino, F.1    Laroche, T.2    Gilson, E.3    Axelrod, A.4    Pillus, L.5    Gasser, S.M.6
  • 33
    • 85038539802 scopus 로고    scopus 로고
    • Sir3p domains involved in the initiation of telomeric silencing in Saccharomyces cerevisiae
    • in press
    • 31a.Park, Y., J. Hanish, and A. J. Lustig. Sir3p domains involved in the initiation of telomeric silencing in Saccharomyces cerevisiae. Genetics, in press.
    • Genetics
    • Park, Y.1    Hanish, J.2    Lustig, A.J.3
  • 34
    • 0002114397 scopus 로고
    • Chromatin structure and epigenetic regulation in yeast
    • S. C. R. Elgin (ed.). IRL press, Oxford, England
    • Pillus, L., and M. Grunstein. 1995. Chromatin structure and epigenetic regulation in yeast, p. 123-146. In S. C. R. Elgin (ed.), Chromatin structure and gene expression. IRL press, Oxford, England.
    • (1995) Chromatin Structure and Gene Expression , pp. 123-146
    • Pillus, L.1    Grunstein, M.2
  • 35
    • 0027184524 scopus 로고
    • Silent domains are assembled continuously from the telomere and are defined by promoter distance and strength, and by SIR3 dosage
    • Renauld, H., O. M. Aparicio, P. D. Zierath, B. L. Billington, S. K. Chhablani, and D. E. Gottschling. 1993. Silent domains are assembled continuously from the telomere and are defined by promoter distance and strength, and by SIR3 dosage. Genes Dev. 7:1133-1145.
    • (1993) Genes Dev. , vol.7 , pp. 1133-1145
    • Renauld, H.1    Aparicio, O.M.2    Zierath, P.D.3    Billington, B.L.4    Chhablani, S.K.5    Gottschling, D.E.6
  • 36
    • 85038544079 scopus 로고    scopus 로고
    • Unpublished data
    • 33a.Renauld, H. Unpublished data.
    • Renauld, H.1
  • 37
    • 0023340731 scopus 로고
    • Four genes responsible for a position effect on expression from HML and HMR in Saccharomyces cerevisiae
    • Rine, J., and I. Herskowitz. 1987. Four genes responsible for a position effect on expression from HML and HMR in Saccharomyces cerevisiae. Genetics 116:9-22.
    • (1987) Genetics , vol.116 , pp. 9-22
    • Rine, J.1    Herskowitz, I.2
  • 39
    • 0025148943 scopus 로고
    • Cis- and trans-acting regulatory elements of the yeast URA3 promoter
    • Roy, A., F. Exinger, and R. Losson. 1990. cis- and trans-acting regulatory elements of the yeast URA3 promoter. Mol. Cell. Biol. 10:5257-5270.
    • (1990) Mol. Cell. Biol. , vol.10 , pp. 5257-5270
    • Roy, A.1    Exinger, F.2    Losson, R.3
  • 41
    • 0024799254 scopus 로고
    • High efficiency transformation of intact yeast cells using single stranded nucleic acids as a carrier
    • Schiestl, R. H., and R. D. Gietz. 1989. High efficiency transformation of intact yeast cells using single stranded nucleic acids as a carrier. Curr. Genet. 16:339-346.
    • (1989) Curr. Genet. , vol.16 , pp. 339-346
    • Schiestl, R.H.1    Gietz, R.D.2
  • 42
    • 85038543821 scopus 로고    scopus 로고
    • Personal communication
    • 38a.Shore, D. Personal communication.
    • Shore, D.1
  • 43
    • 0030820491 scopus 로고    scopus 로고
    • Accelerated aging and nucleolar fragmentation in yeast sgs1 mutants
    • Sinclair, D. A., K. Mills, and L. Guarente. 1997. Accelerated aging and nucleolar fragmentation in yeast sgs1 mutants. Science 277:1313-1316.
    • (1997) Science , vol.277 , pp. 1313-1316
    • Sinclair, D.A.1    Mills, K.2    Guarente, L.3
  • 44
    • 0031056907 scopus 로고    scopus 로고
    • An unusual form of transcriptional silencing in yeast ribosomal DNA
    • Smith, J. S., and J. D. Boeke. 1997. An unusual form of transcriptional silencing in yeast ribosomal DNA. Genes Dev. 11:241-254.
    • (1997) Genes Dev. , vol.11 , pp. 241-254
    • Smith, J.S.1    Boeke, J.D.2
  • 45
    • 0025971103 scopus 로고
    • Assay of yeast mating reaction
    • Sprague, G. F. 1991. Assay of yeast mating reaction. Methods Enzymol. 194: 77-93.
    • (1991) Methods Enzymol. , vol.194 , pp. 77-93
    • Sprague, G.F.1
  • 46
    • 0029807521 scopus 로고    scopus 로고
    • Activation of a MAP kinase cascade leads to Sir3p hyperphosphorylation and strengthens transcriptional silencing
    • Stone, E. M., and L. Pillus. 1996. Activation of a MAP kinase cascade leads to Sir3p hyperphosphorylation and strengthens transcriptional silencing. J. Cell Biol. 135:571-583.
    • (1996) J. Cell Biol. , vol.135 , pp. 571-583
    • Stone, E.M.1    Pillus, L.2
  • 47
    • 0031027431 scopus 로고    scopus 로고
    • SIR2 and SIR4 interactions differ in core and extended telomeric heterochromatin in yeast
    • Strahl-Bolsinger, S., A. Hecht, L. Kunheng, and M. Grunstein. 1997. SIR2 and SIR4 interactions differ in core and extended telomeric heterochromatin in yeast. Genes Dev. 11:83-93.
    • (1997) Genes Dev. , vol.11 , pp. 83-93
    • Strahl-Bolsinger, S.1    Hecht, A.2    Kunheng, L.3    Grunstein, M.4
  • 48
    • 0027322885 scopus 로고
    • Epigenetic switching of transcriptional states: Cis- and trans-acting factors affecting establishment of silencing at the HMR locus in Saccharomyces cerevisiae
    • Sussel, L., D. Vannier, and D. Shore. 1993. Epigenetic switching of transcriptional states: cis- and trans-acting factors affecting establishment of silencing at the HMR locus in Saccharomyces cerevisiae. Mol. Cell. Biol. 13: 3919-3928.
    • (1993) Mol. Cell. Biol. , vol.13 , pp. 3919-3928
    • Sussel, L.1    Vannier, D.2    Shore, D.3
  • 49
    • 0028234142 scopus 로고
    • Histone H3 amino terminus is required for telomeric and silent mating locus repression in yeast
    • Thompson, J. S., X. Ling, and M. Grunstein. 1994. Histone H3 amino terminus is required for telomeric and silent mating locus repression in yeast. Nature 369:245-247.
    • (1994) Nature , vol.369 , pp. 245-247
    • Thompson, J.S.1    Ling, X.2    Grunstein, M.3
  • 50
    • 0029922959 scopus 로고    scopus 로고
    • Role of interactions between the origin recognition complex and SIR1 in transcriptional silencing
    • Triolo, T., and R. Sternglanz. 1996. Role of interactions between the origin recognition complex and SIR1 in transcriptional silencing. Nature 381:251-253.
    • (1996) Nature , vol.381 , pp. 251-253
    • Triolo, T.1    Sternglanz, R.2
  • 51
    • 0030964526 scopus 로고    scopus 로고
    • Silencing factors participate in DNA repair and recombination in Saccharomyces cerevisiae
    • Tsukamoto, Y., J. Kato, and H. Ikeda. 1997. Silencing factors participate in DNA repair and recombination in Saccharomyces cerevisiae. Nature 388: 900-903.
    • (1997) Nature , vol.388 , pp. 900-903
    • Tsukamoto, Y.1    Kato, J.2    Ikeda, H.3
  • 52
    • 0029560752 scopus 로고
    • Heterochromatin and gene expression in Drosophila
    • Weiler, K. S., and B. T. Wakimoto. 1995. Heterochromatin and gene expression in Drosophila. Annu. Rev. Genet. 29:577-605.
    • (1995) Annu. Rev. Genet. , vol.29 , pp. 577-605
    • Weiler, K.S.1    Wakimoto, B.T.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.