-
1
-
-
1542407660
-
Toxic effects of ultraviolet radiation on the skin
-
Matsumura,Y. et al. (2004) Toxic effects of ultraviolet radiation on the skin. Toxicol. Appl. Pharmacol., 195, 298-308.
-
(2004)
Toxicol. Appl. Pharmacol.
, vol.195
, pp. 298-308
-
-
Matsumura, Y.1
-
2
-
-
14644405691
-
Cellular and molecular events leading to the development of skin cancer
-
Melnikova,V.O. et al. (2005) Cellular and molecular events leading to the development of skin cancer. Mutat. Res., 571, 91-106.
-
(2005)
Mutat. Res.
, vol.571
, pp. 91-106
-
-
Melnikova, V.O.1
-
4
-
-
0036834937
-
Ultraviolet-B irradiation and matrix metalloproteinases: from induction via signaling to initial events
-
Brenneisen,P. et al. (2002) Ultraviolet-B irradiation and matrix metalloproteinases: from induction via signaling to initial events. Ann. N. Y. Acad. Sci., 973, 31-43.
-
(2002)
Ann. N. Y. Acad. Sci.
, vol.973
, pp. 31-43
-
-
Brenneisen, P.1
-
5
-
-
13944255488
-
Inhibition of p38 mitogen-activated protein kinase and phosphatidylinositol 3-kinase decreases UVB-induced activator protein-1 and cyclooxygenase-2 in a SKH-1 hairless mouse model
-
Bachelor,M.A. et al. (2005) Inhibition of p38 mitogen-activated protein kinase and phosphatidylinositol 3-kinase decreases UVB-induced activator protein-1 and cyclooxygenase-2 in a SKH-1 hairless mouse model. Mol. Cancer Res., 3, 90-99.
-
(2005)
Mol. Cancer Res.
, vol.3
, pp. 90-99
-
-
Bachelor, M.A.1
-
6
-
-
17844394391
-
Mitogen-activated protein kinase activation in UV-induced signal transduction
-
Bode,A.M. et al. (2003) Mitogen-activated protein kinase activation in UV-induced signal transduction. Sci. STKE, 2003, RE2.
-
(2003)
Sci. STKE
, vol.2003
-
-
Bode, A.M.1
-
7
-
-
79953326318
-
Ultraviolet B radiation activates NF-κB and induces iNOS expression in HR-1 hairless mouse skin: role of IκB kinase-β
-
Chang,E.J. et al. (2011) Ultraviolet B radiation activates NF-κB and induces iNOS expression in HR-1 hairless mouse skin: role of IκB kinase-β. Mol. Carcinog., 50, 310-317.
-
(2011)
Mol. Carcinog.
, vol.50
, pp. 310-317
-
-
Chang, E.J.1
-
8
-
-
0035939790
-
Role of cyclic AMP responsive element in the UVB induction of cyclooxygenase-2 transcription in human keratinocytes
-
Tang,Q. et al. (2001) Role of cyclic AMP responsive element in the UVB induction of cyclooxygenase-2 transcription in human keratinocytes. Oncogene, 20, 5164-5172.
-
(2001)
Oncogene
, vol.20
, pp. 5164-5172
-
-
Tang, Q.1
-
9
-
-
34247260533
-
Modulation of UVB-induced and basal cyclooxygenase-2 (COX-2) expression by apigenin in mouse keratinocytes: role of USF transcription factors
-
Van Dross,R.T. et al. (2007) Modulation of UVB-induced and basal cyclooxygenase-2 (COX-2) expression by apigenin in mouse keratinocytes: role of USF transcription factors. Mol. Carcinog., 46, 303-314.
-
(2007)
Mol. Carcinog.
, vol.46
, pp. 303-314
-
-
Van Dross, R.T.1
-
11
-
-
0031689543
-
Cyclooxygenase in biology and disease
-
Dubois,R.N. et al. (1998) Cyclooxygenase in biology and disease. FASEB J., 12, 1063-1073.
-
(1998)
FASEB J
, vol.12
, pp. 1063-1073
-
-
Dubois, R.N.1
-
12
-
-
0031843401
-
COX-2 expression is induced by UVB exposure in human skin: implications for the development of skin cancer
-
Buckman,S.Y. et al. (1998) COX-2 expression is induced by UVB exposure in human skin: implications for the development of skin cancer. Carcinogenesis, 19, 723-729.
-
(1998)
Carcinogenesis
, vol.19
, pp. 723-729
-
-
Buckman, S.Y.1
-
13
-
-
0037307483
-
Cyclooxygenase a molecular target for cancer prevention and treatment
-
Subbaramaiah,K. et al. (2003) Cyclooxygenase 2: a molecular target for cancer prevention and treatment. Trends Pharmacol. Sci., 24, 96-102.
-
(2003)
Trends Pharmacol. Sci.
, vol.2
, pp. 96-102
-
-
Subbaramaiah, K.1
-
14
-
-
14644416024
-
Photochemoprevention of ultraviolet B signaling and photocarcinogenesis
-
Afaq,F. et al. (2005) Photochemoprevention of ultraviolet B signaling and photocarcinogenesis. Mutat. Res., 571, 153-173.
-
(2005)
Mutat. Res.
, vol.571
, pp. 153-173
-
-
Afaq, F.1
-
15
-
-
0031439247
-
Cellular functions regulated by Src family kinases
-
Thomas,S.M. et al. (1997) Cellular functions regulated by Src family kinases. Annu. Rev. Cell Dev. Biol., 13, 513-609.
-
(1997)
Annu. Rev. Cell Dev. Biol.
, vol.13
, pp. 513-609
-
-
Thomas, S.M.1
-
16
-
-
0041940113
-
Targeted expression of c-Src in epidermal basal cells leads to enhanced skin tumor promotion, malignant progression, and metastasis
-
Matsumoto,T. et al. (2003) Targeted expression of c-Src in epidermal basal cells leads to enhanced skin tumor promotion, malignant progression, and metastasis. Cancer Res., 63, 4819-4828.
-
(2003)
Cancer Res
, vol.63
, pp. 4819-4828
-
-
Matsumoto, T.1
-
17
-
-
0033573921
-
Mechanism of biological synergy between cellular Src and epidermal growth factor receptor
-
Tice,D.A. et al. (1999) Mechanism of biological synergy between cellular Src and epidermal growth factor receptor. Proc. Natl. Acad. Sci. U.S.A., 96, 1415-1420.
-
(1999)
Proc. Natl. Acad. Sci. U. S. A.
, vol.96
, pp. 1415-1420
-
-
Tice, D.A.1
-
18
-
-
0029121267
-
Potentiation of epidermal growth factor receptormediated oncogenesis by c-Src: implications for the etiology of multiple human cancers
-
Maa,M.C. et al. (1995) Potentiation of epidermal growth factor receptormediated oncogenesis by c-Src: implications for the etiology of multiple human cancers. Proc. Natl. Acad. Sci. U.S.A., 92, 6981-6985.
-
(1995)
Proc. Natl. Acad. Sci. U. S. A.
, vol.92
, pp. 6981-6985
-
-
Maa, M.C.1
-
19
-
-
34248591612
-
Targeting the Raf-MEK-ERK mitogen-activated protein kinase cascade for the treatment of cancer
-
Roberts,P.J. et al. (2007) Targeting the Raf-MEK-ERK mitogen-activated protein kinase cascade for the treatment of cancer. Oncogene, 26, 3291-3310.
-
(2007)
Oncogene
, vol.26
, pp. 3291-3310
-
-
Roberts, P.J.1
-
20
-
-
34248226610
-
Apigenin and cancer chemoprevention: progress, potential and promise (review)
-
Patel,D. et al. (2007) Apigenin and cancer chemoprevention: progress, potential and promise (review). Int. J. Oncol., 30, 233-245.
-
(2007)
Int. J. Oncol.
, vol.30
, pp. 233-245
-
-
Patel, D.1
-
21
-
-
0034851475
-
Flavonoid (myricetin, quercetin, kaempferol, luteolin, and apigenin) content of edible tropical plants
-
Miean,K.H. et al. (2001) Flavonoid (myricetin, quercetin, kaempferol, luteolin, and apigenin) content of edible tropical plants. J. Agric. Food Chem., 49, 3106-3112.
-
(2001)
J. Agric. Food Chem.
, vol.49
, pp. 3106-3112
-
-
Miean, K.H.1
-
22
-
-
42349094328
-
Enhancement of UVB-induced apoptosis by apigenin in human keratinocytes and organotypic keratinocyte cultures
-
Abu-Yousif,A.O. et al. (2008) Enhancement of UVB-induced apoptosis by apigenin in human keratinocytes and organotypic keratinocyte cultures. Cancer Res., 68, 3057-3065.
-
(2008)
Cancer Res
, vol.68
, pp. 3057-3065
-
-
Abu-Yousif, A.O.1
-
23
-
-
0031057115
-
Inhibition of ultraviolet light induced skin carcinogenesis in SKH-1 mice by apigenin, a plant flavonoid
-
Birt,D.F. et al. (1997) Inhibition of ultraviolet light induced skin carcinogenesis in SKH-1 mice by apigenin, a plant flavonoid. Anticancer Res., 17(1A), 85-91.
-
(1997)
Anticancer Res
, vol.17
, Issue.1 A
, pp. 85-91
-
-
Birt, D.F.1
-
24
-
-
33845799125
-
Apigenin prevents UVB-induced cyclooxygenase 2 expression: coupled mRNA stabilization and translational inhibition
-
Tong,X. et al. (2007) Apigenin prevents UVB-induced cyclooxygenase 2 expression: coupled mRNA stabilization and translational inhibition. Mol. Cell. Biol., 27, 283-296.
-
(2007)
Mol. Cell. Biol.
, vol.27
, pp. 283-296
-
-
Tong, X.1
-
25
-
-
77950232845
-
Luteolin inhibits protein kinase C(epsilon) and c-Src activities and UVB-induced skin cancer
-
Byun,S. et al. (2010) Luteolin inhibits protein kinase C(epsilon) and c-Src activities and UVB-induced skin cancer. Cancer Res., 70, 2415-2423.
-
(2010)
Cancer Res
, vol.70
, pp. 2415-2423
-
-
Byun, S.1
-
26
-
-
48649090159
-
Myricetin suppresses UVB-induced skin cancer by targeting Fyn
-
Jung,S.K. et al. (2008) Myricetin suppresses UVB-induced skin cancer by targeting Fyn. Cancer Res., 68, 6021-6029.
-
(2008)
Cancer Res
, vol.68
, pp. 6021-6029
-
-
Jung, S.K.1
-
27
-
-
0034334115
-
Signal transduction pathways: targets for chemoprevention of skin cancer
-
Bode,A.M. et al. (2000) Signal transduction pathways: targets for chemoprevention of skin cancer. Lancet Oncol., 1, 181-188.
-
(2000)
Lancet Oncol
, vol.1
, pp. 181-188
-
-
Bode, A.M.1
-
28
-
-
79953069592
-
Growth factor signaling pathways as targets for prevention of epithelial carcinogenesis
-
Rho,O. et al. (2011) Growth factor signaling pathways as targets for prevention of epithelial carcinogenesis. Mol. Carcinog., 50, 264-279..
-
(2011)
Mol. Carcinog.
, vol.50
-
-
Rho, O.1
-
29
-
-
34547397574
-
-
Fritsche,E. et al. (2007) Lightening up the UV response by identification of the arylhydrocarbon receptor as a cytoplasmatic target for ultraviolet B radiation. Proc. Natl. Acad. Sci. U.S.A., 104, 8851-8856.
-
(2007)
, vol.104
, pp. 8851-8856
-
-
Fritsche, E.1
-
30
-
-
60149095366
-
Caffeic acid, a phenolic phytochemical in coffee, directly inhibits Fyn kinase activity and UVB-induced COX-2 expression
-
Kang,N.J. et al. (2009) Caffeic acid, a phenolic phytochemical in coffee, directly inhibits Fyn kinase activity and UVB-induced COX-2 expression. Carcinogenesis, 30, 321-330.
-
(2009)
Carcinogenesis
, vol.30
, pp. 321-330
-
-
Kang, N.J.1
-
31
-
-
70449711373
-
The chemopreventive bioflavonoid apigenin inhibits prostate cancer cell motility through the focal adhesion kinase/Src signaling mechanism
-
Franzen,C.A. et al. (2009) The chemopreventive bioflavonoid apigenin inhibits prostate cancer cell motility through the focal adhesion kinase/Src signaling mechanism. Cancer Prev. Res. (Phila)., 2, 830-841.
-
(2009)
Cancer Prev. Res. (Phila).
, vol.2
, pp. 830-841
-
-
Franzen, C.A.1
-
32
-
-
0142166328
-
Cancer chemoprevention with dietary phytochemicals
-
Surh,Y.J. (2003) Cancer chemoprevention with dietary phytochemicals. Nat. Rev. Cancer, 3, 768-780.
-
(2003)
Nat. Rev. Cancer
, vol.3
, pp. 768-780
-
-
Surh, Y.J.1
-
33
-
-
79952012742
-
Molecular targets of phytochemicals for cancer prevention
-
Lee,K.W. et al. (2011) Molecular targets of phytochemicals for cancer prevention. Nat. Rev. Cancer, 11, 211-218.
-
(2011)
Nat. Rev. Cancer
, vol.11
, pp. 211-218
-
-
Lee, K.W.1
-
34
-
-
33746605173
-
Src protein tyrosine kinase family and acute inflammatory responses
-
Okutani,D. et al. (2006) Src protein tyrosine kinase family and acute inflammatory responses. Am. J. Physiol. Lung Cell Mol. Physiol., 291, L129-L141.
-
(2006)
Am. J. Physiol. Lung Cell Mol. Physiol.
, vol.291
-
-
Okutani, D.1
-
35
-
-
33746114248
-
The crucial role of cyclooxygenase-2 in osteopontininduced protein kinase C alpha/c-Src/IkappaB kinase alpha/beta-dependent prostate tumor progression and angiogenesis
-
Jain,S. et al. (2006) The crucial role of cyclooxygenase-2 in osteopontininduced protein kinase C alpha/c-Src/IkappaB kinase alpha/beta-dependent prostate tumor progression and angiogenesis. Cancer Res., 66, 6638-6648.
-
(2006)
Cancer Res
, vol.66
, pp. 6638-6648
-
-
Jain, S.1
-
37
-
-
0037180757
-
Inflammation and cancer
-
Coussens,L.M. et al. (2002) Inflammation and cancer. Nature, 420, 860-867.
-
(2002)
Nature
, vol.420
, pp. 860-867
-
-
Coussens, L.M.1
-
38
-
-
0034719779
-
Cyclooxygenase-2 and carcinogenesis
-
Prescott,S.M. et al. (2000) Cyclooxygenase-2 and carcinogenesis. Biochim. Biophys. Acta, 1470, M69-M78.
-
(2000)
Biochim. Biophys. Acta
, vol.1470
-
-
Prescott, S.M.1
-
39
-
-
77956042544
-
SRC: a century of science brought to the clinic
-
Aleshin,A. et al. (2010) SRC: a century of science brought to the clinic. Neoplasia, 12, 599-607.
-
(2010)
Neoplasia
, vol.12
, pp. 599-607
-
-
Aleshin, A.1
-
40
-
-
2542532366
-
Tyrosine kinase inhibition reduces inflammation in the acute stage of experimental pneumococcal meningitis
-
Angstwurm,K. et al. (2004) Tyrosine kinase inhibition reduces inflammation in the acute stage of experimental pneumococcal meningitis. Infect. Immun., 72, 3294-3298.
-
(2004)
Infect. Immun.
, vol.72
, pp. 3294-3298
-
-
Angstwurm, K.1
-
41
-
-
27544479318
-
Role of tyrosine kinase inhibitors in cancer therapy
-
Arora,A. et al. (2005) Role of tyrosine kinase inhibitors in cancer therapy. J. Pharmacol. Exp. Ther., 315, 971-979.
-
(2005)
J. Pharmacol. Exp. Ther.
, vol.315
, pp. 971-979
-
-
Arora, A.1
-
42
-
-
84873544590
-
-
Schrödinger Suite Schrödinger, LLC, New York, NY
-
Schrödinger Suite (2011) Schrödinger, LLC, New York, NY
-
(2011)
-
-
-
43
-
-
0033954256
-
-
Berman,H.M. et al. (2000) The Protein Data Bank. Nucleic Acids Res., 28, 235-242.
-
(2000)
, vol.28
, pp. 235-242
-
-
Berman, H.M.1
-
44
-
-
0033001789
-
-
Xu,W. et al. (1999) Crystal structures of c-Src reveal features of its autoinhibitory mechanism. Mol. Cell, 3, 629-638.
-
(1999)
Mol. Cell
, vol.3
, pp. 629-638
-
-
Xu, W.1
-
45
-
-
4444221565
-
UCSF Chimera-a visualization system for exploratory research and analysis
-
Pettersen,E.F. et al. (2004) UCSF Chimera-a visualization system for exploratory research and analysis. J. Comput. Chem., 25, 1605-1612.
-
(2004)
J. Comput. Chem.
, vol.25
, pp. 1605-1612
-
-
Pettersen, E.F.1
-
46
-
-
0032894567
-
Signaling through focal adhesion kinase
-
Schlaepfer,D.D. et al. (1999) Signaling through focal adhesion kinase. Prog. Biophys. Mol. Biol., 71, 435-478.
-
(1999)
Prog. Biophys. Mol. Biol.
, vol.71
, pp. 435-478
-
-
Schlaepfer, D.D.1
-
47
-
-
33748286819
-
Integrin-regulated FAK-Src signaling in normal and cancer cells
-
Mitra,S.K. et al. (2006) Integrin-regulated FAK-Src signaling in normal and cancer cells. Curr. Opin. Cell Biol., 18, 516-523.
-
(2006)
Curr. Opin. Cell Biol.
, vol.18
, pp. 516-523
-
-
Mitra, S.K.1
|