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Volumn 27, Issue 2, 2013, Pages 251-257

Emodin regulates apoptotic pathway in human liver cancer cells

Author keywords

Bcl 2; emodin; signaling pathway

Indexed keywords

ALANINE; BH3 PROTEIN; CASPASE 8; CASPASE 9; CYTOCHROME C; EMODIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PROTEIN BAX; PROTEIN BCL 2; PROTEIN P53; REACTIVE OXYGEN METABOLITE; TRANSCRIPTION FACTOR RELA;

EID: 84873405972     PISSN: 0951418X     EISSN: 10991573     Source Type: Journal    
DOI: 10.1002/ptr.4703     Document Type: Article
Times cited : (51)

References (37)
  • 1
    • 0032575714 scopus 로고    scopus 로고
    • Death receptors: Signaling and modulation
    • Ashkenazi A,. 1998. Death receptors: signaling and modulation. Science 281: 1305-1308.
    • (1998) Science , vol.281 , pp. 1305-1308
    • Ashkenazi, A.1
  • 2
    • 41149152733 scopus 로고    scopus 로고
    • How do BCL-2 proteins induce mitochondrial outer membrane permeabilization?
    • Chipuk JE, Green DR,. 2008. How do BCL-2 proteins induce mitochondrial outer membrane permeabilization? Trends Cell Biol 18: 157-164.
    • (2008) Trends Cell Biol , vol.18 , pp. 157-164
    • Chipuk, J.E.1    Green, D.R.2
  • 3
    • 56249101739 scopus 로고    scopus 로고
    • Assessing mitochondrial outer embrane permeabilization during apoptosis
    • Dave Z, Byfield M, Bossy-Wetzel E,. 2008. Assessing mitochondrial outer embrane permeabilization during apoptosis. Methods 46: 319-323.
    • (2008) Methods , vol.46 , pp. 319-323
    • Dave, Z.1    Byfield, M.2    Bossy-Wetzel, E.3
  • 4
    • 0036139524 scopus 로고    scopus 로고
    • Reactive oxygen species and signal transduction
    • Finkel T,. 2001. Reactive oxygen species and signal transduction. IUBMB Life 52: 3-6.
    • (2001) IUBMB Life , vol.52 , pp. 3-6
    • Finkel, T.1
  • 5
    • 0028633536 scopus 로고
    • A multiwell assay for inhibitors of phosphatidylinositol 3-kinase and the identification of natural product inhibitors
    • Frew T, Powis G, Berggren M, et al., 1994. A multiwell assay for inhibitors of phosphatidylinositol 3-kinase and the identification of natural product inhibitors. Anticancer Res 14: 2425-2428.
    • (1994) Anticancer Res , vol.14 , pp. 2425-2428
    • Frew, T.1    Powis, G.2    Berggren, M.3
  • 6
    • 54249083134 scopus 로고    scopus 로고
    • A dietary anthocyanidin delphinidin induces apoptosis of human prostate cancer PC3 cells in vitro and in vivo: Involvement of nuclear factor-κB signaling
    • Hafeez BB, Siddiqui IA, Asim M, et al., 2008. A dietary anthocyanidin delphinidin induces apoptosis of human prostate cancer PC3 cells in vitro and in vivo: involvement of nuclear factor-κB signaling. Cancer Res 68: 8564-8572.
    • (2008) Cancer Res , vol.68 , pp. 8564-8572
    • Hafeez, B.B.1    Siddiqui, I.A.2    Asim, M.3
  • 7
    • 0028568315 scopus 로고
    • Cell cycle control and cancer
    • Hartwell LH, Kastan MB,. 1994. Cell cycle control and cancer. Science 266: 1821-1828.
    • (1994) Science , vol.266 , pp. 1821-1828
    • Hartwell, L.H.1    Kastan, M.B.2
  • 8
    • 0034641918 scopus 로고    scopus 로고
    • The biochemistry of apoptosis
    • Hengartner MO,. 2000. The biochemistry of apoptosis. Nature 407: 770-776.
    • (2000) Nature , vol.407 , pp. 770-776
    • Hengartner, M.O.1
  • 9
    • 0028625746 scopus 로고
    • A rapid and simple method for the isolation of apoptotic DNA fragments
    • Herrmann M,. 1994. A rapid and simple method for the isolation of apoptotic DNA fragments. Nucleic Acids Res 22: 5506-5507.
    • (1994) Nucleic Acids Res , vol.22 , pp. 5506-5507
    • Herrmann, M.1
  • 11
    • 33745231161 scopus 로고    scopus 로고
    • Emodin inhibits tumor cell adhesion through disruption of the membrane lipid raft-associated integrin signaling pathway
    • Huang Q, Shen HM, Shui G, Wenk MR, Ong CN,. 2006. Emodin inhibits tumor cell adhesion through disruption of the membrane lipid raft-associated integrin signaling pathway. Cancer Res 66: 5807-5815.
    • (2006) Cancer Res , vol.66 , pp. 5807-5815
    • Huang, Q.1    Shen, H.M.2    Shui, G.3    Wenk, M.R.4    Ong, C.N.5
  • 12
    • 45349099696 scopus 로고    scopus 로고
    • Emodin enhances cytotoxicity of chemotherapeutic drugs in prostate cancer cells: The mechanisms involve ROS-mediated suppression of multidrug resistance and hypoxia inducible factor-1
    • Huang XZ, Wang J, Huang C, et al., 2008. Emodin enhances cytotoxicity of chemotherapeutic drugs in prostate cancer cells: the mechanisms involve ROS-mediated suppression of multidrug resistance and hypoxia inducible factor-1. Cancer Biol Ther 7: 468-475.
    • (2008) Cancer Biol Ther , vol.7 , pp. 468-475
    • Huang, X.Z.1    Wang, J.2    Huang, C.3
  • 13
    • 0034190367 scopus 로고    scopus 로고
    • Recent advances towards understanding redox mechanisms in the activation of nuclear factor kappaB
    • Janssen-Heininger YM, Poynter ME, Baeuerle PA,. 2000. Recent advances towards understanding redox mechanisms in the activation of nuclear factor kappaB. Free Radic Biol Med 28: 1317-1327.
    • (2000) Free Radic Biol Med , vol.28 , pp. 1317-1327
    • Janssen-Heininger, Y.M.1    Poynter, M.E.2    Baeuerle, P.A.3
  • 15
    • 0034068601 scopus 로고    scopus 로고
    • Mitochondrial control of cell death
    • Kroemer G, Reed JC,. 2000. Mitochondrial control of cell death. Nat Med 6: 513-519.
    • (2000) Nat Med , vol.6 , pp. 513-519
    • Kroemer, G.1    Reed, J.C.2
  • 16
    • 65549120715 scopus 로고    scopus 로고
    • Modes of p53 regulation
    • Kruse JP, Gu W,. 2009. Modes of p53 regulation. Cell 137: 609-622.
    • (2009) Cell , vol.137 , pp. 609-622
    • Kruse, J.P.1    Gu, W.2
  • 17
    • 0345276414 scopus 로고    scopus 로고
    • Bcl-2-family proteins and the role of mitochondria in apoptosis
    • Kuwana T, Newmeyer DD,. 2003. Bcl-2-family proteins and the role of mitochondria in apoptosis. Curr Opin Cell Biol 15: 691-699.
    • (2003) Curr Opin Cell Biol , vol.15 , pp. 691-699
    • Kuwana, T.1    Newmeyer, D.D.2
  • 18
    • 70350203951 scopus 로고    scopus 로고
    • Emodin induces a reactive oxygen species-dependent and ATM-p53-Bax mediated cytotoxicity in lung cancer cells
    • Lai JM, Chang JT, Wen CL, Hsu SL,. 2009. Emodin induces a reactive oxygen species-dependent and ATM-p53-Bax mediated cytotoxicity in lung cancer cells. Eur J Pharmacol 623: 1-9.
    • (2009) Eur J Pharmacol , vol.623 , pp. 1-9
    • Lai, J.M.1    Chang, J.T.2    Wen, C.L.3    Hsu, S.L.4
  • 19
    • 0034183775 scopus 로고    scopus 로고
    • Cell cycle control as a basis for cancer drug development
    • McDonald ER, El-Deiry WS,. 2000. Cell cycle control as a basis for cancer drug development. Int J Oncol 16: 871-886.
    • (2000) Int J Oncol , vol.16 , pp. 871-886
    • McDonald, E.R.1    El-Deiry, W.S.2
  • 20
    • 36849028626 scopus 로고    scopus 로고
    • Lucifer's labyrinth-ten years of path finding in cell death
    • Meier P, Vousden KH,. 2007. Lucifer's labyrinth-ten years of path finding in cell death. Mol Cell 28: 746-754.
    • (2007) Mol Cell , vol.28 , pp. 746-754
    • Meier, P.1    Vousden, K.H.2
  • 22
    • 70349932423 scopus 로고    scopus 로고
    • Autodock4 and AutoDockTools4: Automated docking with selective receptor flexiblity
    • Morris GM, Huey R, Lindstrom W, et al., 2009. Autodock4 and AutoDockTools4: automated docking with selective receptor flexiblity. J Comput Chem 30: 2785-2791.
    • (2009) J Comput Chem , vol.30 , pp. 2785-2791
    • Morris, G.M.1    Huey, R.2    Lindstrom, W.3
  • 24
    • 0034820022 scopus 로고    scopus 로고
    • Cell cycle regulation in the G1 phase: A promising target for the development of new chemotherapeutic anticancer agents
    • Owa T, Yoshino H, Yoshimatsu K, Nagasu T,. 2000. Cell cycle regulation in the G1 phase: a promising target for the development of new chemotherapeutic anticancer agents. Curr Med Chem 8: 1487-1503.
    • (2000) Curr Med Chem , vol.8 , pp. 1487-1503
    • Owa, T.1    Yoshino, H.2    Yoshimatsu, K.3    Nagasu, T.4
  • 25
    • 0031754828 scopus 로고    scopus 로고
    • Mechanisms of CD95 (APO-1/Fas)-mediated apoptosis
    • Peter ME,. 1998. Mechanisms of CD95 (APO-1/Fas)-mediated apoptosis. Curr Opin Immunol 10: 545-551.
    • (1998) Curr Opin Immunol , vol.10 , pp. 545-551
    • Peter, M.E.1
  • 26
    • 0038786580 scopus 로고    scopus 로고
    • Apoptosis-targeted therapies for cancer
    • Reed JC,. 2003. Apoptosis-targeted therapies for cancer. Cancer Cell 3: 17-22.
    • (2003) Cancer Cell , vol.3 , pp. 17-22
    • Reed, J.C.1
  • 27
    • 0034873185 scopus 로고    scopus 로고
    • Reactive oxygen species as intracellular messengers during cell growth and differentiation
    • Sauer H, Wartenberg M, Hescheler J,. 2001. Reactive oxygen species as intracellular messengers during cell growth and differentiation. Cell Physiol Biochem 11: 173-186.
    • (2001) Cell Physiol Biochem , vol.11 , pp. 173-186
    • Sauer, H.1    Wartenberg, M.2    Hescheler, J.3
  • 28
    • 0032536771 scopus 로고    scopus 로고
    • Two CD95 (APO-1/Fas) signaling pathways
    • Scaffidi C,. 1998. Two CD95 (APO-1/Fas) signaling pathways. EMBO J 17: 1675-1687.
    • (1998) EMBO J , vol.17 , pp. 1675-1687
    • Scaffidi, C.1
  • 29
    • 65349136027 scopus 로고    scopus 로고
    • Mitochondrial outer membrane proteins assist Bid in Bax-mediated lipidic pore formation
    • Schafer B, Quispe J, Choudhary V, et al., 2009. Mitochondrial outer membrane proteins assist Bid in Bax-mediated lipidic pore formation. Mol Biol Cell 20: 2276-2285.
    • (2009) Mol Biol Cell , vol.20 , pp. 2276-2285
    • Schafer, B.1    Quispe, J.2    Choudhary, V.3
  • 30
    • 1342324038 scopus 로고    scopus 로고
    • Emodin-induced apoptosis through p53-dependent pathway in human hepatoma cells
    • Shieh DE, Chen YY, Yen MH, Chiang LC, Lin CC,. 2004. Emodin-induced apoptosis through p53-dependent pathway in human hepatoma cells. Life Sci 74: 2279-2290.
    • (2004) Life Sci , vol.74 , pp. 2279-2290
    • Shieh, D.E.1    Chen, Y.Y.2    Yen, M.H.3    Chiang, L.C.4    Lin, C.C.5
  • 31
    • 0042206721 scopus 로고    scopus 로고
    • Emodin induces apoptosis of human cervical cancer cells through poly (ADP-ribose) polymerase cleavage and activation of caspase-9
    • Srinivas G, Anto RJ, Srinivas P, Vidhyalakshmi S, Senan VP, Karunagaran D,. 2003. Emodin induces apoptosis of human cervical cancer cells through poly (ADP-ribose) polymerase cleavage and activation of caspase-9. Eur J Pharmacol 473: 117-125.
    • (2003) Eur J Pharmacol , vol.473 , pp. 117-125
    • Srinivas, G.1    Anto, R.J.2    Srinivas, P.3    Vidhyalakshmi, S.4    Senan, V.P.5    Karunagaran, D.6
  • 32
    • 0038052800 scopus 로고    scopus 로고
    • The cell cycle: A review of regulation, deregulation and therapeutic targets in cancer
    • Vermeulen K, Berneman ZN, Van Bockstaele DR,. 2003. The cell cycle: a review of regulation, deregulation and therapeutic targets in cancer. Cell Prolif 36: 165-175.
    • (2003) Cell Prolif , vol.36 , pp. 165-175
    • Vermeulen, K.1    Berneman, Z.N.2    Van Bockstaele, D.R.3
  • 33
    • 0032508414 scopus 로고    scopus 로고
    • NF-κB antiapoptosis: Induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to suppress caspase-8 activation
    • Wang CY,. 1998. NF-κB antiapoptosis: induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to suppress caspase-8 activation. Science 281: 1680-1683.
    • (1998) Science , vol.281 , pp. 1680-1683
    • Wang, C.Y.1
  • 35
    • 1642535590 scopus 로고    scopus 로고
    • Emodin enhances arsenic trioxide-induced apoptosis via generation of reactive oxygen species and inhibition of survival signaling
    • Yi J, Yang J, He R, et al., 2004. Emodin enhances arsenic trioxide-induced apoptosis via generation of reactive oxygen species and inhibition of survival signaling. Cancer Res 64: 108-116.
    • (2004) Cancer Res , vol.64 , pp. 108-116
    • Yi, J.1    Yang, J.2    He, R.3
  • 36
    • 33947171644 scopus 로고    scopus 로고
    • Changes in mitochondrial membrane potential and reactive oxygen species during wogonin- induced cell death in human hepatoma cells
    • Yu JQ, Liu HB, Tian DZ, Liu YW, Lei JC, Zou GL,. 2007. Changes in mitochondrial membrane potential and reactive oxygen species during wogonin- induced cell death in human hepatoma cells. Hepatol Res 37: 68-76.
    • (2007) Hepatol Res , vol.37 , pp. 68-76
    • Yu, J.Q.1    Liu, H.B.2    Tian, D.Z.3    Liu, Y.W.4    Lei, J.C.5    Zou, G.L.6
  • 37
    • 0030067015 scopus 로고    scopus 로고
    • Sensitization of HER-2/neuoverexpressing non-small cell lung cancer cells to chemotherapeutic drugs by tyrosine kinase inhibitor emodin
    • Zhang L, Hung MC,. 1996. Sensitization of HER-2/neuoverexpressing non-small cell lung cancer cells to chemotherapeutic drugs by tyrosine kinase inhibitor emodin. Oncogene 12: 571-576.
    • (1996) Oncogene , vol.12 , pp. 571-576
    • Zhang, L.1    Hung, M.C.2


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