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Bioorganic and Medicinal Chemistry

Volumn 21, Issue 4, 2013, Pages 957-963

Discovery of novel inhibitors of LEDGF/p75-IN protein-protein interactions

(6) Sanchez, Tino Wilson a Debnath, Bikash a Christ, Frauke b Otake, Hiroyuki a Debyser, Zeger b Neamati, Nouri a

a UNIVERSITY OF SOUTHERN CALIFORNIA (United States)

b DEPARTMENT OF PHARMACEUTICAL AND PHARMACOLOGICAL SCIENCES (Belgium)

Author keywords

Antiviral; HIV; Hydrazines; Integrase; LEDGF p75; N Acylhydrazones

Indexed keywords

4 [2 [1 (2 BROMOPHENYL)ETHYLIDENE]HYDRAZINYL] N (2 METHOXYPHENYL) 3 NITROBENZENESULFONAMIDE; 4 [4 (4 METHOXYBENZYL) 1,4 DIAZEPAM 1 YL] 3 NITRO N PHENYLBENZENESULFONAMIDE; HYDRAZINE DERIVATIVE; HYDRAZONE DERIVATIVE; INTEGRASE; INTEGRASE INHIBITOR; ISONIAZID; LENS EPITHELIUM DERIVED GROWTH FACTOR; PROTEIN P75; UNCLASSIFIED DRUG;

ANTIVIRAL ACTIVITY; ANTIVIRAL SUSCEPTIBILITY; ARTICLE; DRUG IDENTIFICATION; DRUG STRUCTURE; HUMAN; HUMAN CELL; MOLECULAR DOCKING; NONHUMAN; PROCESS OPTIMIZATION; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; PROTEIN PURIFICATION; STRUCTURE ACTIVITY RELATION;

AMINO ACID SEQUENCE; BINDING SITES; CELL LINE; CELL PROLIFERATION; DRUG EVALUATION, PRECLINICAL; HIV INTEGRASE; HIV INTEGRASE INHIBITORS; HUMANS; HYDRAZINES; HYDRAZONES; IMIDES; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; MOLECULAR DOCKING SIMULATION; PEPTIDES; PROTEIN INTERACTION MAPS; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT PROTEINS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84873294197 PISSN: 09680896 EISSN: 14643391 Source Type: Journal
DOI: 10.1016/j.bmc.2012.12.012 Document Type: Article

Times cited : (30)

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