Isoniazid: Metabolic aspects and toxicological correlates

Current Drug Metabolism

Volumn 8, Issue 8, 2007, Pages 839-851

  Preziosi, Paolo ^a  

^a CATHOLIC UNIVERSITY   (Italy)

Author keywords

oxoacid hydrazones; Acetylhydrazide; Acetylisoniazid; Ammonia; Cytochrome P450 (CYP); Diacetylhydrazine; GABA; Hepatotoxicity; Hydrazine; Isoniazid; L arginine; L glutamic acid; Neurotoxicity

Indexed keywords

4 AMINOBENZOIC ACID; ACETOHYDRAZIDE; ACETYLISONIAZID; ACYLTRANSFERASE; AMMONIA; ANTACID AGENT; CARBAMAZEPINE; CATALASE; CYTOCHROME P450; DRUG METABOLITE; ERDOSTEINE; ETHOSUXIMIDE; HYDRALAZINE; HYDRAZINE; HYDRAZONE DERIVATIVE; ISONIAZID; ISONICOTINAMIDE; ISONICOTINIC ACID; PARACETAMOL; PHENELZINE; PHENOBARBITAL; PHENYTOIN; PYRIDOXINE; SELENIUM; SULFONAMIDE; SUPEROXIDE DISMUTASE; THEOPHYLLINE; TOLBUTAMIDE; TRIAZOLAM; UNINDEXED DRUG;

ANTIOXIDANT ACTIVITY; ATOPY; CARDIOTOXICITY; CORRELATION ANALYSIS; DOSE RESPONSE; DRUG ABSORPTION; DRUG ACETYLATION; DRUG BLOOD LEVEL; DRUG COMPETITION; DRUG DOSE COMPARISON; DRUG ELIMINATION; DRUG EXCRETION; DRUG EXPOSURE; DRUG HALF LIFE; DRUG HYDROLYSIS; DRUG MEGADOSE; DRUG METABOLISM; DRUG OXIDATION; DRUG PENETRATION; DRUG PROTEIN BINDING; DRUG TOLERABILITY; DRUG TRANSFORMATION; DRUG URINE LEVEL; DRUG WITHDRAWAL; ENZYME ACTIVITY; FIRST PASS EFFECT; FOOD; FOOD DRUG INTERACTION; GENETIC POLYMORPHISM; HUMAN; LIVER CARCINOMA; LIVER DISEASE; LIVER TOXICITY; LUPUS ERYTHEMATOSUS; MAXIMUM PLASMA CONCENTRATION; MYCOBACTERIUM BOVIS; MYCOBACTERIUM TUBERCULOSIS; NEUROPROTECTION; NEUROTOXICITY; NONHUMAN; OXIDATIVE STRESS; PELLAGRA; PERIPHERAL NEUROPATHY; PHARMACODYNAMICS; PHARMACOGENETICS; REPEATED DRUG DOSE; REVIEW; SINGLE DRUG DOSE; TIME TO MAXIMUM PLASMA CONCENTRATION; TUBERCULOSIS;

ANTITUBERCULAR AGENTS; CYTOCHROME P-450 ENZYME SYSTEM; ISONIAZID; MEDLINE;

EID: 36949027885     PISSN: 13892002     EISSN: None     Source Type: Journal    
DOI: 10.2174/138920007782798216     Document Type: Review

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