메뉴 건너뛰기




Volumn 34, Issue 2, 2013, Pages 50-58

Invariant natural killer T cells as sensors and managers of inflammation

Author keywords

CD1d; Glycolipids; Immunotherapy; Inflammation; Invariant natural killer T cells

Indexed keywords

ALPHA GALACTOSYLCERAMIDE; CD1D ANTIGEN; CD4 ANTIGEN; DECTIN 1; GAMMA INTERFERON; GLYCOSPHINGOLIPID; INTERLEUKIN 12; INTERLEUKIN 13; INTERLEUKIN 2 RECEPTOR ALPHA; INTERLEUKIN 2 RECEPTOR BETA; INTERLEUKIN 22; INTERLEUKIN 4; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; MESSENGER RNA; NEUROTRANSMITTER; OXIDIZED LOW DENSITY LIPOPROTEIN; PATTERN RECOGNITION RECEPTOR; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PROMYELOCYTIC LEUKEMIA PROTEIN; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 4; TOLL LIKE RECEPTOR 5; TOLL LIKE RECEPTOR 8; TOLL LIKE RECEPTOR 9; TRANSCRIPTION FACTOR FOXP3; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR ALPHA;

EID: 84873130090     PISSN: 14714906     EISSN: 14714981     Source Type: Journal    
DOI: 10.1016/j.it.2012.08.009     Document Type: Review
Times cited : (88)

References (105)
  • 1
    • 0038228956 scopus 로고    scopus 로고
    • The regulatory role of Va14 NKT cells in innate and acquired immune response
    • Taniguchi M., et al. The regulatory role of Va14 NKT cells in innate and acquired immune response. Annu. Rev. Immunol. 2003, 21:483-513.
    • (2003) Annu. Rev. Immunol. , vol.21 , pp. 483-513
    • Taniguchi, M.1
  • 2
    • 2542448243 scopus 로고    scopus 로고
    • CD1: antigen presentation and T cell function
    • Brigl M., Brenner M.B. CD1: antigen presentation and T cell function. Annu. Rev. Immunol. 2004, 22:817-890.
    • (2004) Annu. Rev. Immunol. , vol.22 , pp. 817-890
    • Brigl, M.1    Brenner, M.B.2
  • 3
    • 17144374753 scopus 로고    scopus 로고
    • Toward an understanding of NKT cell biology: progress and paradoxes
    • Kronenberg M. Toward an understanding of NKT cell biology: progress and paradoxes. Annu. Rev. Immunol. 2005, 26:877-900.
    • (2005) Annu. Rev. Immunol. , vol.26 , pp. 877-900
    • Kronenberg, M.1
  • 4
    • 34247842744 scopus 로고    scopus 로고
    • The biology of NKT cells
    • Bendelac A., et al. The biology of NKT cells. Annu. Rev. Immunol. 2007, 25:297-336.
    • (2007) Annu. Rev. Immunol. , vol.25 , pp. 297-336
    • Bendelac, A.1
  • 5
    • 34247577500 scopus 로고    scopus 로고
    • NKT cells: T lymphocytes with innate effector functions
    • Van Kaer L. NKT cells: T lymphocytes with innate effector functions. Curr. Opin. Immunol. 2007, 19:354-364.
    • (2007) Curr. Opin. Immunol. , vol.19 , pp. 354-364
    • Van Kaer, L.1
  • 6
    • 78650963869 scopus 로고    scopus 로고
    • Endogenous collagen peptide activation of CD1d-restricted NKT cells ameliorates tissue-specific inflammation in mice
    • Liu Y., et al. Endogenous collagen peptide activation of CD1d-restricted NKT cells ameliorates tissue-specific inflammation in mice. J. Clin. Invest. 2011, 121:249-264.
    • (2011) J. Clin. Invest. , vol.121 , pp. 249-264
    • Liu, Y.1
  • 7
    • 19344371631 scopus 로고    scopus 로고
    • + NKT cells patrolling liver sinusoids
    • + NKT cells patrolling liver sinusoids. PLoS Biol. 2005, 3:650-661.
    • (2005) PLoS Biol. , vol.3 , pp. 650-661
    • Geissmann, F.1
  • 8
    • 80555139637 scopus 로고    scopus 로고
    • Airborne lipid antigens mobilize resident intravascular NKT cells to induce allergic airway inflammation
    • Scanlon S.T., et al. Airborne lipid antigens mobilize resident intravascular NKT cells to induce allergic airway inflammation. J. Exp. Med. 2011, 208:2113-2124.
    • (2011) J. Exp. Med. , vol.208 , pp. 2113-2124
    • Scanlon, S.T.1
  • 9
    • 34249059942 scopus 로고    scopus 로고
    • - iNKT cell population involved in airway neutrophilia
    • - iNKT cell population involved in airway neutrophilia. J. Exp. Med. 2007, 204:995-1001.
    • (2007) J. Exp. Med. , vol.204 , pp. 995-1001
    • Michel, M.L.1
  • 10
    • 79251578351 scopus 로고    scopus 로고
    • - invariant NKT cells to bacteria
    • - invariant NKT cells to bacteria. J. Immunol. 2011, 186:662-666.
    • (2011) J. Immunol. , vol.186 , pp. 662-666
    • Doisne, J.M.1
  • 11
    • 83755166410 scopus 로고    scopus 로고
    • Identification of Bcl-6-dependent follicular helper NKT cells that provide cognate help for B cell responses
    • Chang P.P., et al. Identification of Bcl-6-dependent follicular helper NKT cells that provide cognate help for B cell responses. Nat. Immunol. 2012, 13:35-43.
    • (2012) Nat. Immunol. , vol.13 , pp. 35-43
    • Chang, P.P.1
  • 12
    • 83755166409 scopus 로고    scopus 로고
    • Invariant natural killer T cells direct B cell responses to cognate lipid antigen in an IL-21-dependent manner
    • King I.L., et al. Invariant natural killer T cells direct B cell responses to cognate lipid antigen in an IL-21-dependent manner. Nat. Immunol. 2012, 13:44-50.
    • (2012) Nat. Immunol. , vol.13 , pp. 44-50
    • King, I.L.1
  • 13
    • 84859377986 scopus 로고    scopus 로고
    • + T cell help
    • + T cell help. J. Immunol. 2012, 188:3217-3222.
    • (2012) J. Immunol. , vol.188 , pp. 3217-3222
    • Tonti, E.1
  • 14
    • 77956943528 scopus 로고    scopus 로고
    • + invariant NKT cells induced by TGF-b
    • + invariant NKT cells induced by TGF-b. J. Immunol. 2010, 185:2157-2163.
    • (2010) J. Immunol. , vol.185 , pp. 2157-2163
    • Monteiro, M.1
  • 16
    • 78650575791 scopus 로고    scopus 로고
    • Invariant NK T cells: potential for immunotherapeutic targeting with glycolipid antigens
    • Van Kaer L., et al. Invariant NK T cells: potential for immunotherapeutic targeting with glycolipid antigens. Immunotherapy 2011, 3:59-75.
    • (2011) Immunotherapy , vol.3 , pp. 59-75
    • Van Kaer, L.1
  • 17
    • 50049084627 scopus 로고    scopus 로고
    • The BTB-zinc finger transcriptional regulator PLZF controls the development of invariant natural killer T cell effector functions
    • Kovalovsky D., et al. The BTB-zinc finger transcriptional regulator PLZF controls the development of invariant natural killer T cell effector functions. Nat. Immunol. 2008, 9:1055-1064.
    • (2008) Nat. Immunol. , vol.9 , pp. 1055-1064
    • Kovalovsky, D.1
  • 18
    • 51349121407 scopus 로고    scopus 로고
    • The transcription factor PLZF directs the effector program of the NKT cell lineage
    • Savage A.K., et al. The transcription factor PLZF directs the effector program of the NKT cell lineage. Immunity 2008, 29:391-403.
    • (2008) Immunity , vol.29 , pp. 391-403
    • Savage, A.K.1
  • 19
    • 77649234578 scopus 로고    scopus 로고
    • How invariant natural killer T cells respond to infection by recognizing microbial or endogenous lipid antigens
    • Brigl M., Brenner M.B. How invariant natural killer T cells respond to infection by recognizing microbial or endogenous lipid antigens. Semin. Immunol. 2010, 22:79-86.
    • (2010) Semin. Immunol. , vol.22 , pp. 79-86
    • Brigl, M.1    Brenner, M.B.2
  • 20
    • 80052966551 scopus 로고    scopus 로고
    • Invariant natural killer T cells recognize glycolipids from pathogenic Gram-positive bacteria
    • Kinjo Y., et al. Invariant natural killer T cells recognize glycolipids from pathogenic Gram-positive bacteria. Nat. Immunol. 2011, 12:966-974.
    • (2011) Nat. Immunol. , vol.12 , pp. 966-974
    • Kinjo, Y.1
  • 21
    • 78650944895 scopus 로고    scopus 로고
    • Influenza infection in suckling mice expands an NKT cell subset that protects against airway hyperreactivity
    • Chang Y.J., et al. Influenza infection in suckling mice expands an NKT cell subset that protects against airway hyperreactivity. J. Clin. Invest. 2011, 121:57-69.
    • (2011) J. Clin. Invest. , vol.121 , pp. 57-69
    • Chang, Y.J.1
  • 22
    • 22944439737 scopus 로고    scopus 로고
    • Human CD1-restricted T cell recognition of lipids from pollens
    • Agea E., et al. Human CD1-restricted T cell recognition of lipids from pollens. J. Exp. Med. 2005, 202:295-308.
    • (2005) J. Exp. Med. , vol.202 , pp. 295-308
    • Agea, E.1
  • 23
    • 79958281073 scopus 로고    scopus 로고
    • Invariant NKT cells are required for airway inflammation induced by environmental antigens
    • Wingender G., et al. Invariant NKT cells are required for airway inflammation induced by environmental antigens. J. Exp. Med. 2011, 208:1151-1162.
    • (2011) J. Exp. Med. , vol.208 , pp. 1151-1162
    • Wingender, G.1
  • 24
    • 0030696696 scopus 로고    scopus 로고
    • CD1d-restricted and TCR-mediated activation of Va14 NKT cells by glycosylceramides
    • Kawano T., et al. CD1d-restricted and TCR-mediated activation of Va14 NKT cells by glycosylceramides. Science 1997, 278:1626-1629.
    • (1997) Science , vol.278 , pp. 1626-1629
    • Kawano, T.1
  • 25
    • 84861732299 scopus 로고    scopus 로고
    • Strategy of lipid recognition by invariant natural killer T cells: 'one for all and all for one'
    • Mallevaey T., Selvanantham T. Strategy of lipid recognition by invariant natural killer T cells: 'one for all and all for one'. Immunology 2012, 136:273-282.
    • (2012) Immunology , vol.136 , pp. 273-282
    • Mallevaey, T.1    Selvanantham, T.2
  • 26
    • 4644221871 scopus 로고    scopus 로고
    • Quantitative and qualitative differences in the in vivo response of NKT cells to distinct a- and b-anomeric glycolipids
    • Parekh V.V., et al. Quantitative and qualitative differences in the in vivo response of NKT cells to distinct a- and b-anomeric glycolipids. J. Immunol. 2004, 173:3693-3706.
    • (2004) J. Immunol. , vol.173 , pp. 3693-3706
    • Parekh, V.V.1
  • 27
    • 1642454720 scopus 로고    scopus 로고
    • Dissociation of NKT stimulation, cytokine induction, and NK activation in vivo by the use of distinct TCR-binding ceramides
    • Ortaldo J.R., et al. Dissociation of NKT stimulation, cytokine induction, and NK activation in vivo by the use of distinct TCR-binding ceramides. J. Immunol. 2004, 172:943-953.
    • (2004) J. Immunol. , vol.172 , pp. 943-953
    • Ortaldo, J.R.1
  • 28
    • 70350585024 scopus 로고    scopus 로고
    • Alpha versus beta: are we on the way to resolve the mystery as to which is the endogenous ligand for natural killer T cells?
    • Ilan Y. Alpha versus beta: are we on the way to resolve the mystery as to which is the endogenous ligand for natural killer T cells?. Clin. Exp. Immunol. 2009, 158:300-307.
    • (2009) Clin. Exp. Immunol. , vol.158 , pp. 300-307
    • Ilan, Y.1
  • 29
    • 79958248405 scopus 로고    scopus 로고
    • Innate and cytokine-driven signals, rather than microbial antigens, dominate in natural killer T cell activation during microbial infection
    • Brigl M., et al. Innate and cytokine-driven signals, rather than microbial antigens, dominate in natural killer T cell activation during microbial infection. J. Exp. Med. 2011, 208:1163-1177.
    • (2011) J. Exp. Med. , vol.208 , pp. 1163-1177
    • Brigl, M.1
  • 30
    • 0347776209 scopus 로고    scopus 로고
    • Mechanism of CD1d-restricted natural killer T cell activation during microbial infection
    • Brigl M., et al. Mechanism of CD1d-restricted natural killer T cell activation during microbial infection. Nat. Immunol. 2003, 4:1230-1237.
    • (2003) Nat. Immunol. , vol.4 , pp. 1230-1237
    • Brigl, M.1
  • 31
    • 58149277749 scopus 로고    scopus 로고
    • Cutting edge: the mechanism of invariant NKT cell responses to viral danger signals
    • Tyznik A.J., et al. Cutting edge: the mechanism of invariant NKT cell responses to viral danger signals. J. Immunol. 2008, 181:4452-4456.
    • (2008) J. Immunol. , vol.181 , pp. 4452-4456
    • Tyznik, A.J.1
  • 32
    • 48249103545 scopus 로고    scopus 로고
    • NK cell-like behavior of Va14i NK T cells during MCMV infection
    • Wesley J.D., et al. NK cell-like behavior of Va14i NK T cells during MCMV infection. PLoS Pathog. 2008, 4:e1000106.
    • (2008) PLoS Pathog. , vol.4
    • Wesley, J.D.1
  • 33
    • 35448936431 scopus 로고    scopus 로고
    • Activation of invariant NKT cells by toll-like receptor 9-stimulated dendritic cells requires type I interferon and charged glycosphingolipids
    • Paget C., et al. Activation of invariant NKT cells by toll-like receptor 9-stimulated dendritic cells requires type I interferon and charged glycosphingolipids. Immunity 2007, 27:597-609.
    • (2007) Immunity , vol.27 , pp. 597-609
    • Paget, C.1
  • 34
    • 38049184505 scopus 로고    scopus 로고
    • Modulation of human natural killer T cell ligands on TLR-mediated antigen-presenting cell activation
    • Salio M., et al. Modulation of human natural killer T cell ligands on TLR-mediated antigen-presenting cell activation. Proc. Natl. Acad. Sci. U.S.A. 2007, 104:20490-20495.
    • (2007) Proc. Natl. Acad. Sci. U.S.A. , vol.104 , pp. 20490-20495
    • Salio, M.1
  • 35
    • 81755180767 scopus 로고    scopus 로고
    • Innate recognition of cell wall b-glucans drives invariant natural killer T cell responses against fungi
    • Cohen N.R., et al. Innate recognition of cell wall b-glucans drives invariant natural killer T cell responses against fungi. Cell Host Microbe 2011, 10:437-450.
    • (2011) Cell Host Microbe , vol.10 , pp. 437-450
    • Cohen, N.R.1
  • 36
    • 33847361128 scopus 로고    scopus 로고
    • Invariant NKT cells amplify the innate immune response to lipopolysaccharide
    • Nagarajan N.A., Kronenberg M. Invariant NKT cells amplify the innate immune response to lipopolysaccharide. J. Immunol. 2007, 178:2706-2713.
    • (2007) J. Immunol. , vol.178 , pp. 2706-2713
    • Nagarajan, N.A.1    Kronenberg, M.2
  • 37
    • 33751572483 scopus 로고    scopus 로고
    • IFN-b-mediated up-regulation of CD1d in bacteria-infected APCs
    • Raghuraman G., et al. IFN-b-mediated up-regulation of CD1d in bacteria-infected APCs. J. Immunol. 2006, 177:7841-7848.
    • (2006) J. Immunol. , vol.177 , pp. 7841-7848
    • Raghuraman, G.1
  • 38
    • 3042606551 scopus 로고    scopus 로고
    • Effects of infection and inflammation on lipid and lipoprotein metabolism: mechanisms and consequences to the host
    • Khovidhunkit W., et al. Effects of infection and inflammation on lipid and lipoprotein metabolism: mechanisms and consequences to the host. J. Lipid Res. 2004, 45:1169-1196.
    • (2004) J. Lipid Res. , vol.45 , pp. 1169-1196
    • Khovidhunkit, W.1
  • 39
    • 77649247780 scopus 로고    scopus 로고
    • Activation state and intracellular trafficking contribute to the repertoire of endogenous glycosphingolipids presented by CD1d
    • Muindi K., et al. Activation state and intracellular trafficking contribute to the repertoire of endogenous glycosphingolipids presented by CD1d. Proc. Natl. Acad. Sci. U.S.A. 2010, 107:3052-3057.
    • (2010) Proc. Natl. Acad. Sci. U.S.A. , vol.107 , pp. 3052-3057
    • Muindi, K.1
  • 40
    • 20144389877 scopus 로고    scopus 로고
    • Exogenous and endogenous glycolipid antigens activate NKT cells during microbial infections
    • Mattner J., et al. Exogenous and endogenous glycolipid antigens activate NKT cells during microbial infections. Nature 2005, 434:525-529.
    • (2005) Nature , vol.434 , pp. 525-529
    • Mattner, J.1
  • 41
    • 77955865125 scopus 로고    scopus 로고
    • Lysosomal a-galactosidase controls the generation of self lipid antigens for natural killer T cells
    • Darmoise A., et al. Lysosomal a-galactosidase controls the generation of self lipid antigens for natural killer T cells. Immunity 2010, 33:216-228.
    • (2010) Immunity , vol.33 , pp. 216-228
    • Darmoise, A.1
  • 42
    • 0037452710 scopus 로고    scopus 로고
    • Defective presentation of the CD1d1-restricted natural Va14Ja18 NKT lymphocyte antigen caused by b-D-glucosylceramide synthase deficiency
    • Stanic A.K., et al. Defective presentation of the CD1d1-restricted natural Va14Ja18 NKT lymphocyte antigen caused by b-D-glucosylceramide synthase deficiency. Proc. Natl. Acad. Sci. U.S.A. 2003, 100:1849-1854.
    • (2003) Proc. Natl. Acad. Sci. U.S.A. , vol.100 , pp. 1849-1854
    • Stanic, A.K.1
  • 43
    • 0036143535 scopus 로고    scopus 로고
    • Multiple defects in antigen presentation and T cell development by mice expressing cytoplasmic tail-truncated CD1d
    • Chiu Y.H., et al. Multiple defects in antigen presentation and T cell development by mice expressing cytoplasmic tail-truncated CD1d. Nat. Immunol. 2002, 3:55-60.
    • (2002) Nat. Immunol. , vol.3 , pp. 55-60
    • Chiu, Y.H.1
  • 44
    • 10044280324 scopus 로고    scopus 로고
    • Lysosomal glycosphingolipid recognition by NKT cells
    • Zhou D., et al. Lysosomal glycosphingolipid recognition by NKT cells. Science 2004, 306:1786-1789.
    • (2004) Science , vol.306 , pp. 1786-1789
    • Zhou, D.1
  • 45
    • 34247613348 scopus 로고    scopus 로고
    • Implications for invariant natural killer T cell ligands due to the restricted presence of isoglobotrihexosylceramide in mammals
    • Speak A.O., et al. Implications for invariant natural killer T cell ligands due to the restricted presence of isoglobotrihexosylceramide in mammals. Proc. Natl. Acad. Sci. U.S.A. 2007, 104:5971-5976.
    • (2007) Proc. Natl. Acad. Sci. U.S.A. , vol.104 , pp. 5971-5976
    • Speak, A.O.1
  • 46
    • 67049155299 scopus 로고    scopus 로고
    • Immunologic glycosphingolipidomics and NKT cell development in mouse thymus
    • Li Y., et al. Immunologic glycosphingolipidomics and NKT cell development in mouse thymus. J. Proteome Res. 2009, 8:2740-2751.
    • (2009) J. Proteome Res. , vol.8 , pp. 2740-2751
    • Li, Y.1
  • 47
    • 34247592222 scopus 로고    scopus 로고
    • Normal development and function of invariant natural killer T cells in mice with isoglobotrihexosylceramide (iGb3) deficiency
    • Porubsky S., et al. Normal development and function of invariant natural killer T cells in mice with isoglobotrihexosylceramide (iGb3) deficiency. Proc. Natl. Acad. Sci. U.S.A. 2007, 104:5977-5982.
    • (2007) Proc. Natl. Acad. Sci. U.S.A. , vol.104 , pp. 5977-5982
    • Porubsky, S.1
  • 48
    • 34248233051 scopus 로고    scopus 로고
    • Distinct endosomal trafficking requirements for presentation of autoantigens and exogenous lipids by human CD1d molecules
    • Chen X., et al. Distinct endosomal trafficking requirements for presentation of autoantigens and exogenous lipids by human CD1d molecules. J. Immunol. 2007, 178:6181-6190.
    • (2007) J. Immunol. , vol.178 , pp. 6181-6190
    • Chen, X.1
  • 49
    • 84866150230 scopus 로고    scopus 로고
    • Globosides but not isoglobosides can impact the development of invariant NKT cells and their interaction with dendritic cells
    • Porubsky S., et al. Globosides but not isoglobosides can impact the development of invariant NKT cells and their interaction with dendritic cells. J. Immunol. 2012, 189:3007-3017.
    • (2012) J. Immunol. , vol.189 , pp. 3007-3017
    • Porubsky, S.1
  • 50
    • 79251564431 scopus 로고    scopus 로고
    • Diverse endogenous antigens for mouse NKT cells: self-antigens that are not glycosphingolipids
    • Pei B., et al. Diverse endogenous antigens for mouse NKT cells: self-antigens that are not glycosphingolipids. J. Immunol. 2011, 186:1348-1360.
    • (2011) J. Immunol. , vol.186 , pp. 1348-1360
    • Pei, B.1
  • 51
    • 0034143918 scopus 로고    scopus 로고
    • Murine CD1d-restricted T cell recognition of cellular lipids
    • Gumperz J.E., et al. Murine CD1d-restricted T cell recognition of cellular lipids. Immunity 2000, 12:211-221.
    • (2000) Immunity , vol.12 , pp. 211-221
    • Gumperz, J.E.1
  • 52
    • 70350503426 scopus 로고    scopus 로고
    • Recognition of lyso-phospholipids by human natural killer T lymphocytes
    • Fox L.M., et al. Recognition of lyso-phospholipids by human natural killer T lymphocytes. PLoS Biol. 2009, 7:e1000228.
    • (2009) PLoS Biol. , vol.7
    • Fox, L.M.1
  • 53
    • 84859927634 scopus 로고    scopus 로고
    • Peroxisome-derived lipids are self antigens that stimulate invariant natural killer T cells in the thymus
    • Facciotti F., et al. Peroxisome-derived lipids are self antigens that stimulate invariant natural killer T cells in the thymus. Nat. Immunol. 2012, 13:474-480.
    • (2012) Nat. Immunol. , vol.13 , pp. 474-480
    • Facciotti, F.1
  • 54
    • 81255208437 scopus 로고    scopus 로고
    • Invariant natural killer T cells recognize lipid self antigen induced by microbial danger signals
    • Brennan P.J., et al. Invariant natural killer T cells recognize lipid self antigen induced by microbial danger signals. Nat. Immunol. 2011, 12:1202-1211.
    • (2011) Nat. Immunol. , vol.12 , pp. 1202-1211
    • Brennan, P.J.1
  • 55
    • 3142688053 scopus 로고    scopus 로고
    • Activation of PPARg specifies a dendritic cell subtype capable of enhanced induction of iNKT cell expansion
    • Szatmari I., et al. Activation of PPARg specifies a dendritic cell subtype capable of enhanced induction of iNKT cell expansion. Immunity 2004, 21:95-106.
    • (2004) Immunity , vol.21 , pp. 95-106
    • Szatmari, I.1
  • 56
    • 4644293314 scopus 로고    scopus 로고
    • Natural killer T cells accelerate atherogenesis in mice
    • Nakai Y., et al. Natural killer T cells accelerate atherogenesis in mice. Blood 2004, 104:2051-2059.
    • (2004) Blood , vol.104 , pp. 2051-2059
    • Nakai, Y.1
  • 57
    • 79961119915 scopus 로고    scopus 로고
    • CD1d-independent activation of invariant natural killer T cells by staphylococcal enterotoxin B through major histocompatibility complex class II/T cell receptor interaction results in acute lung injury
    • Rieder S.A., et al. CD1d-independent activation of invariant natural killer T cells by staphylococcal enterotoxin B through major histocompatibility complex class II/T cell receptor interaction results in acute lung injury. Infect. Immun. 2011, 79:3141-3148.
    • (2011) Infect. Immun. , vol.79 , pp. 3141-3148
    • Rieder, S.A.1
  • 58
    • 84864847925 scopus 로고    scopus 로고
    • CD1d-independent activation of mouse and human iNKT cells by bacterial superantigens
    • Hayworth J.L., et al. CD1d-independent activation of mouse and human iNKT cells by bacterial superantigens. Immunol. Cell Biol. 2012, 90:699-709.
    • (2012) Immunol. Cell Biol. , vol.90 , pp. 699-709
    • Hayworth, J.L.1
  • 59
    • 33748296238 scopus 로고    scopus 로고
    • FcgRIII engagement provides activating signals to NKT cells in antibody-induced joint inflammation
    • Kim H.Y., et al. FcgRIII engagement provides activating signals to NKT cells in antibody-induced joint inflammation. J. Clin. Invest. 2006, 116:2484-2492.
    • (2006) J. Clin. Invest. , vol.116 , pp. 2484-2492
    • Kim, H.Y.1
  • 60
    • 0029904115 scopus 로고    scopus 로고
    • + T cells upon NKR-P1 cross-linking
    • + T cells upon NKR-P1 cross-linking. J. Exp. Med. 1996, 183:2391-2396.
    • (1996) J. Exp. Med. , vol.183 , pp. 2391-2396
    • Arase, H.1
  • 61
    • 0032494097 scopus 로고    scopus 로고
    • CD161 (NKR-P1A) costimulation of CD1d-dependent activation of human T cells expressing invariant Va24 JaQ T cell receptor a chains
    • Exley M., et al. CD161 (NKR-P1A) costimulation of CD1d-dependent activation of human T cells expressing invariant Va24 JaQ T cell receptor a chains. J. Exp. Med. 1998, 188:867-876.
    • (1998) J. Exp. Med. , vol.188 , pp. 867-876
    • Exley, M.1
  • 62
    • 79959755773 scopus 로고    scopus 로고
    • NKG2D performs two functions in invariant NKT cells: direct TCR-independent activation of NK-like cytolysis and co-stimulation of activation by CD1d
    • Kuylenstierna C., et al. NKG2D performs two functions in invariant NKT cells: direct TCR-independent activation of NK-like cytolysis and co-stimulation of activation by CD1d. Eur. J. Immunol. 2011, 41:1913-1923.
    • (2011) Eur. J. Immunol. , vol.41 , pp. 1913-1923
    • Kuylenstierna, C.1
  • 63
    • 78650527898 scopus 로고    scopus 로고
    • NKT cell costimulation: experimental progress and therapeutic promise
    • van den Heuvel M.J., et al. NKT cell costimulation: experimental progress and therapeutic promise. Trends Mol. Med. 2011, 17:65-77.
    • (2011) Trends Mol. Med. , vol.17 , pp. 65-77
    • van den Heuvel, M.J.1
  • 64
    • 78149486214 scopus 로고    scopus 로고
    • Apoptotic cells activate NKT cells through T cell Ig-like mucin-like-1 resulting in airway hyperreactivity
    • Lee H.H., et al. Apoptotic cells activate NKT cells through T cell Ig-like mucin-like-1 resulting in airway hyperreactivity. J. Immunol. 2010, 185:5225-5235.
    • (2010) J. Immunol. , vol.185 , pp. 5225-5235
    • Lee, H.H.1
  • 65
    • 84864298403 scopus 로고    scopus 로고
    • Costimulatory activation of murine invariant natural killer T cells by toll-like receptor agonists
    • Kulkarni R.R., et al. Costimulatory activation of murine invariant natural killer T cells by toll-like receptor agonists. Cell. Immunol. 2012, 277:33-43.
    • (2012) Cell. Immunol. , vol.277 , pp. 33-43
    • Kulkarni, R.R.1
  • 66
    • 80053604734 scopus 로고    scopus 로고
    • Functional innervation of hepatic iNKT cells is immunosuppressive following stroke
    • Wong C.H., et al. Functional innervation of hepatic iNKT cells is immunosuppressive following stroke. Science 2011, 334:101-105.
    • (2011) Science , vol.334 , pp. 101-105
    • Wong, C.H.1
  • 67
    • 66449108669 scopus 로고    scopus 로고
    • Cd1d-dependent regulation of bacterial colonization in the intestine of mice
    • Nieuwenhuis E.E., et al. Cd1d-dependent regulation of bacterial colonization in the intestine of mice. J. Clin. Invest. 2009, 119:1241-1250.
    • (2009) J. Clin. Invest. , vol.119 , pp. 1241-1250
    • Nieuwenhuis, E.E.1
  • 68
    • 57449088879 scopus 로고    scopus 로고
    • Invariant NKT cells reduce the immunosuppressive activity of influenza A virus-induced myeloid-derived suppressor cells in mice and humans
    • De Santo C., et al. Invariant NKT cells reduce the immunosuppressive activity of influenza A virus-induced myeloid-derived suppressor cells in mice and humans. J. Clin. Invest. 2008, 118:4036-4048.
    • (2008) J. Clin. Invest. , vol.118 , pp. 4036-4048
    • De Santo, C.1
  • 69
    • 84858587977 scopus 로고    scopus 로고
    • Interleukin-22 is produced by invariant natural killer T lymphocytes during influenza A virus infection: potential role in protection against lung epithelial damages
    • Paget C., et al. Interleukin-22 is produced by invariant natural killer T lymphocytes during influenza A virus infection: potential role in protection against lung epithelial damages. J. Biol. Chem. 2012, 287:8816-8829.
    • (2012) J. Biol. Chem. , vol.287 , pp. 8816-8829
    • Paget, C.1
  • 70
    • 84864453237 scopus 로고    scopus 로고
    • B-cells and IL-4 promote methylcholanthrene-induced carcinogenesis but there is no evidence for a role of T/NKT-cells and their effector molecules (Fas-ligand, TNF-a, perforin)
    • Kammertoens T., et al. B-cells and IL-4 promote methylcholanthrene-induced carcinogenesis but there is no evidence for a role of T/NKT-cells and their effector molecules (Fas-ligand, TNF-a, perforin). Int. J. Cancer 2012, 131:1499-1508.
    • (2012) Int. J. Cancer , vol.131 , pp. 1499-1508
    • Kammertoens, T.1
  • 71
    • 61449255982 scopus 로고    scopus 로고
    • A phase I-II study of a-galactosylceramide-pulsed IL-2/GM-CSF-cultured peripheral blood mononuclear cells in patients with advanced and recurrent non-small cell lung cancer
    • Motohashi S., et al. A phase I-II study of a-galactosylceramide-pulsed IL-2/GM-CSF-cultured peripheral blood mononuclear cells in patients with advanced and recurrent non-small cell lung cancer. J. Immunol. 2009, 182:2492-2501.
    • (2009) J. Immunol. , vol.182 , pp. 2492-2501
    • Motohashi, S.1
  • 72
    • 67649890782 scopus 로고    scopus 로고
    • Combination therapy of in vitro-expanded natural killer T cells and a-galactosylceramide-pulsed antigen-presenting cells in patients with recurrent head and neck carcinoma
    • Kunii N., et al. Combination therapy of in vitro-expanded natural killer T cells and a-galactosylceramide-pulsed antigen-presenting cells in patients with recurrent head and neck carcinoma. Cancer Sci. 2009, 100:1092-1098.
    • (2009) Cancer Sci. , vol.100 , pp. 1092-1098
    • Kunii, N.1
  • 73
    • 78649848463 scopus 로고    scopus 로고
    • Role of NKT cells in allergic asthma
    • Iwamura C., Nakayama T. Role of NKT cells in allergic asthma. Curr. Opin. Immunol. 2010, 22:807-813.
    • (2010) Curr. Opin. Immunol. , vol.22 , pp. 807-813
    • Iwamura, C.1    Nakayama, T.2
  • 74
    • 78851470200 scopus 로고    scopus 로고
    • A natural protective function of invariant NKT cells in a mouse model of innate-cell-driven lung inflammation
    • Bourgeois E.A., et al. A natural protective function of invariant NKT cells in a mouse model of innate-cell-driven lung inflammation. Eur. J. Immunol. 2011, 41:299-305.
    • (2011) Eur. J. Immunol. , vol.41 , pp. 299-305
    • Bourgeois, E.A.1
  • 75
    • 77954079583 scopus 로고    scopus 로고
    • Natural killer T cells and atherosclerosis: form and function meet pathogenesis
    • Braun N.A., et al. Natural killer T cells and atherosclerosis: form and function meet pathogenesis. J. Innate Immun. 2010, 2:316-324.
    • (2010) J. Innate Immun. , vol.2 , pp. 316-324
    • Braun, N.A.1
  • 76
    • 79251472175 scopus 로고    scopus 로고
    • Invariant natural killer T cells: linking inflammation and neovascularization in human atherosclerosis
    • Kyriakakis E., et al. Invariant natural killer T cells: linking inflammation and neovascularization in human atherosclerosis. Eur. J. Immunol. 2010, 40:3268-3279.
    • (2010) Eur. J. Immunol. , vol.40 , pp. 3268-3279
    • Kyriakakis, E.1
  • 77
    • 70350435777 scopus 로고    scopus 로고
    • Effect of natural killer T cell activation on the initiation of atherosclerosis
    • van Puijvelde G.H., et al. Effect of natural killer T cell activation on the initiation of atherosclerosis. Thromb. Haemost. 2009, 102:223-230.
    • (2009) Thromb. Haemost. , vol.102 , pp. 223-230
    • van Puijvelde, G.H.1
  • 78
    • 84872277296 scopus 로고    scopus 로고
    • Blocking IL-25 signalling protects against gut inflammation in a type-2 model of colitis by suppressing nuocyte and NKT derived IL-13
    • Camelo A., et al. Blocking IL-25 signalling protects against gut inflammation in a type-2 model of colitis by suppressing nuocyte and NKT derived IL-13. J. Gastroenterol. 2012, 47:1198-1211.
    • (2012) J. Gastroenterol. , vol.47 , pp. 1198-1211
    • Camelo, A.1
  • 79
    • 69249155107 scopus 로고    scopus 로고
    • + cells amass in human omentum and are depleted in patients with cancer and obesity
    • + cells amass in human omentum and are depleted in patients with cancer and obesity. Eur. J. Immunol. 2009, 39:1893-1901.
    • (2009) Eur. J. Immunol. , vol.39 , pp. 1893-1901
    • Lynch, L.1
  • 80
    • 84873181067 scopus 로고    scopus 로고
    • Role of NKT cells in the pathogenesis of NAFLD
    • Tajiri K., Shimizu Y. Role of NKT cells in the pathogenesis of NAFLD. Int. J. Hepatol. 2012, 10.1155/2012/850836.
    • (2012) Int. J. Hepatol.
    • Tajiri, K.1    Shimizu, Y.2
  • 81
    • 84873100699 scopus 로고    scopus 로고
    • Contribution of lipid-reactive natural killer T cells to obesity-associated inflammation and insulin resistance. Adipocyte (in press)
    • Wu, L. and Van Kaer, L. (2012) Contribution of lipid-reactive natural killer T cells to obesity-associated inflammation and insulin resistance. Adipocyte (in press).
    • (2012)
    • Wu, L.1    Van Kaer, L.2
  • 82
    • 84865041500 scopus 로고    scopus 로고
    • NKT-associated hedgehog and osteopontin drive fibrogenesis in non-alcoholic fatty liver disease
    • Syn W.K., et al. NKT-associated hedgehog and osteopontin drive fibrogenesis in non-alcoholic fatty liver disease. Gut 2012, 61:1323-1329.
    • (2012) Gut , vol.61 , pp. 1323-1329
    • Syn, W.K.1
  • 83
    • 84863808516 scopus 로고    scopus 로고
    • Short-term high-fat-diet challenge promotes alternative macrophage polarization in adipose tissue via natural killer T cells and interleukin-4
    • Ji Y., et al. Short-term high-fat-diet challenge promotes alternative macrophage polarization in adipose tissue via natural killer T cells and interleukin-4. J. Biol. Chem. 2012, 287:24378-24386.
    • (2012) J. Biol. Chem. , vol.287 , pp. 24378-24386
    • Ji, Y.1
  • 84
    • 84860794660 scopus 로고    scopus 로고
    • Activation of invariant natural killer T cells by lipid excess promotes tissue inflammation, insulin resistance, and hepatic steatosis in obese mice
    • Wu L., et al. Activation of invariant natural killer T cells by lipid excess promotes tissue inflammation, insulin resistance, and hepatic steatosis in obese mice. Proc. Natl. Acad. Sci. U.S.A. 2012, 109:E1143-E1152.
    • (2012) Proc. Natl. Acad. Sci. U.S.A. , vol.109
    • Wu, L.1
  • 85
    • 33646016323 scopus 로고    scopus 로고
    • Adoptive transfer of regulatory NKT lymphocytes ameliorates non-alcoholic steatohepatitis and glucose intolerance in ob/ob mice and is associated with intrahepatic CD8 trapping
    • Elinav E., et al. Adoptive transfer of regulatory NKT lymphocytes ameliorates non-alcoholic steatohepatitis and glucose intolerance in ob/ob mice and is associated with intrahepatic CD8 trapping. J. Pathol. 2006, 209:121-128.
    • (2006) J. Pathol. , vol.209 , pp. 121-128
    • Elinav, E.1
  • 86
    • 53249101515 scopus 로고    scopus 로고
    • Probiotics improve high fat diet-induced hepatic steatosis and insulin resistance by increasing hepatic NKT cells
    • Ma X., et al. Probiotics improve high fat diet-induced hepatic steatosis and insulin resistance by increasing hepatic NKT cells. J. Hepatol. 2008, 49:821-830.
    • (2008) J. Hepatol. , vol.49 , pp. 821-830
    • Ma, X.1
  • 87
    • 84857470273 scopus 로고    scopus 로고
    • Type II NKT cells stimulate diet-induced obesity by mediating adipose tissue inflammation, steatohepatitis and insulin resistance
    • Satoh M., et al. Type II NKT cells stimulate diet-induced obesity by mediating adipose tissue inflammation, steatohepatitis and insulin resistance. PLoS ONE 2012, 7:e30568.
    • (2012) PLoS ONE , vol.7
    • Satoh, M.1
  • 88
    • 80053324882 scopus 로고    scopus 로고
    • Impact of CD1d deficiency on metabolism
    • Kotas M.E., et al. Impact of CD1d deficiency on metabolism. PLoS ONE 2011, 6:e25478.
    • (2011) PLoS ONE , vol.6
    • Kotas, M.E.1
  • 89
    • 79958022995 scopus 로고    scopus 로고
    • + T-cells are not protected against the metabolic abnormalities of diet-induced obesity
    • + T-cells are not protected against the metabolic abnormalities of diet-induced obesity. PLoS ONE 2011, 6:e19831.
    • (2011) PLoS ONE , vol.6
    • Mantell, B.S.1
  • 90
    • 84865992180 scopus 로고    scopus 로고
    • Natural killer T cells in adipose tissue prevent insulin resistance
    • Schipper H.S., et al. Natural killer T cells in adipose tissue prevent insulin resistance. J. Clin. Invest. 2012, 122:3343-3354.
    • (2012) J. Clin. Invest. , vol.122 , pp. 3343-3354
    • Schipper, H.S.1
  • 91
    • 75149169811 scopus 로고    scopus 로고
    • Natural killer T cells are involved in adipose tissues inflammation and glucose intolerance in diet-induced obese mice
    • Ohmura K., et al. Natural killer T cells are involved in adipose tissues inflammation and glucose intolerance in diet-induced obese mice. Arterioscler. Thromb. Vasc. Biol. 2010, 30:193-199.
    • (2010) Arterioscler. Thromb. Vasc. Biol. , vol.30 , pp. 193-199
    • Ohmura, K.1
  • 92
    • 84859997837 scopus 로고    scopus 로고
    • Activation of natural killer T cells promotes M2 macrophage polarization in adipose tissue and improves systemic glucose tolerance via interleukin-4 (IL-4)/STAT6 protein signaling axis in obesity
    • Ji Y., et al. Activation of natural killer T cells promotes M2 macrophage polarization in adipose tissue and improves systemic glucose tolerance via interleukin-4 (IL-4)/STAT6 protein signaling axis in obesity. J. Biol. Chem. 2012, 287:13561-13571.
    • (2012) J. Biol. Chem. , vol.287 , pp. 13561-13571
    • Ji, Y.1
  • 93
    • 33749003142 scopus 로고    scopus 로고
    • Glucocerebroside ameliorates the metabolic syndrome in OB/OB mice
    • Margalit M., et al. Glucocerebroside ameliorates the metabolic syndrome in OB/OB mice. J. Pharmacol. Exp. Ther. 2006, 319:105-110.
    • (2006) J. Pharmacol. Exp. Ther. , vol.319 , pp. 105-110
    • Margalit, M.1
  • 94
    • 79960442267 scopus 로고    scopus 로고
    • Targeting iNKT cells for the treatment of sickle cell disease
    • Field J.J., et al. Targeting iNKT cells for the treatment of sickle cell disease. Clin. Immunol. 2011, 140:177-183.
    • (2011) Clin. Immunol. , vol.140 , pp. 177-183
    • Field, J.J.1
  • 95
    • 84860334955 scopus 로고    scopus 로고
    • Depletion of invariant NKT cells reduces inflammation-induced preterm delivery in mice
    • Li L.P., et al. Depletion of invariant NKT cells reduces inflammation-induced preterm delivery in mice. J. Immunol. 2012, 188:4681-4689.
    • (2012) J. Immunol. , vol.188 , pp. 4681-4689
    • Li, L.P.1
  • 96
    • 1542511203 scopus 로고    scopus 로고
    • NKT cells: what's in a name?
    • Godfrey D.I., et al. NKT cells: what's in a name?. Nat. Rev. Immunol. 2004, 4:231-237.
    • (2004) Nat. Rev. Immunol. , vol.4 , pp. 231-237
    • Godfrey, D.I.1
  • 97
    • 79959375627 scopus 로고    scopus 로고
    • + T cell antigen receptor defines a population of natural killer T cells with distinct glycolipid antigen-recognition properties
    • + T cell antigen receptor defines a population of natural killer T cells with distinct glycolipid antigen-recognition properties. Nat. Immunol. 2011, 12:616-623.
    • (2011) Nat. Immunol. , vol.12 , pp. 616-623
    • Uldrich, A.P.1
  • 98
    • 84864116698 scopus 로고    scopus 로고
    • Lower TCR repertoire diversity in Traj18-deficient mice
    • Bedel R., et al. Lower TCR repertoire diversity in Traj18-deficient mice. Nat. Immunol. 2012, 13:705-706.
    • (2012) Nat. Immunol. , vol.13 , pp. 705-706
    • Bedel, R.1
  • 99
    • 77954628293 scopus 로고    scopus 로고
    • Oligoclonality and innate-like features in the TCR repertoire of type II NKT cells reactive to a b-linked self-glycolipid
    • Arrenberg P., et al. Oligoclonality and innate-like features in the TCR repertoire of type II NKT cells reactive to a b-linked self-glycolipid. Proc. Natl. Acad. Sci. U.S.A. 2010, 107:10984-10989.
    • (2010) Proc. Natl. Acad. Sci. U.S.A. , vol.107 , pp. 10984-10989
    • Arrenberg, P.1
  • 100
    • 1842682026 scopus 로고    scopus 로고
    • Prevention of autoimmunity by targeting a distinct, noninvariant CD1d-reactive T cell population reactive to sulfatide
    • Jahng A., et al. Prevention of autoimmunity by targeting a distinct, noninvariant CD1d-reactive T cell population reactive to sulfatide. J. Exp. Med. 2004, 199:947-957.
    • (2004) J. Exp. Med. , vol.199 , pp. 947-957
    • Jahng, A.1
  • 101
    • 84865392751 scopus 로고    scopus 로고
    • Identification of novel glycolipid ligands activating a sulfatide reactive, CD1d-restricted, type II natural killer T lymphocyte
    • Rhost S., et al. Identification of novel glycolipid ligands activating a sulfatide reactive, CD1d-restricted, type II natural killer T lymphocyte. Eur. J. Immunol. 2012, 42:2851-2860.
    • (2012) Eur. J. Immunol. , vol.42 , pp. 2851-2860
    • Rhost, S.1
  • 102
    • 84861988021 scopus 로고    scopus 로고
    • Microbiota, disease, and back to health: a metastable journey
    • Blumberg R., Powrie F. Microbiota, disease, and back to health: a metastable journey. Sci. Transl. Med. 2012, 4:137rv137.
    • (2012) Sci. Transl. Med. , vol.4
    • Blumberg, R.1    Powrie, F.2
  • 103
    • 77949316299 scopus 로고    scopus 로고
    • + T cells shape the formation of invariant NKT cells
    • + T cells shape the formation of invariant NKT cells. J. Immunol. 2010, 184:1218-1226.
    • (2010) J. Immunol. , vol.184 , pp. 1218-1226
    • Wei, B.1
  • 104
    • 84860216630 scopus 로고    scopus 로고
    • Microbial exposure during early life has persistent effects on natural killer T cell function
    • Olszak T., et al. Microbial exposure during early life has persistent effects on natural killer T cell function. Science 2012, 336:489-493.
    • (2012) Science , vol.336 , pp. 489-493
    • Olszak, T.1
  • 105
    • 84864283284 scopus 로고    scopus 로고
    • Intestinal microbes affect phenotypes and functions of invariant natural killer T cells in mice
    • Wingender G., et al. Intestinal microbes affect phenotypes and functions of invariant natural killer T cells in mice. Gastroenterology 2012, 143:418-428.
    • (2012) Gastroenterology , vol.143 , pp. 418-428
    • Wingender, G.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.