-
1
-
-
0034604451
-
Crystal structure of rhodopsin: A G protein-coupled receptor
-
DOI 10.1126/science.289.5480.739
-
Pawlczewski, K., Kumasaka, T., Hori, T., Behnke, C. A., Motoshima, H., Fox, B. A., Le Trong, I., Teller, D. C., Okada, T., Stenkamp, R. E. et al. (2000) Crystal structure of rhodopsin: A G protein-coupled receptor. Science 289, 739-745 (Pubitemid 30650186)
-
(2000)
Science
, vol.289
, Issue.5480
, pp. 739-745
-
-
Palczewski, K.1
Kumasaka, T.2
Hori, T.3
Behnke, C.A.4
Motoshima, H.5
Fox, B.A.6
Le Trong, I.7
Teller, D.C.8
Okada, T.9
Stenkamp, R.E.10
Yamamoto, M.11
Miyano, M.12
-
2
-
-
36448995359
-
2-adrenergic G protein-coupled receptor
-
DOI 10.1126/science.1150577
-
2-adrenergic G protein-coupled receptor. Science 318, 1258-1265 (Pubitemid 350172884)
-
(2007)
Science
, vol.318
, Issue.5854
, pp. 1258-1265
-
-
Cherezov, V.1
Rosenbaum, D.M.2
Hanson, M.A.3
Rasmussen, S.G.F.4
Foon, S.T.5
Kobilka, T.S.6
Choi, H.-J.7
Kuhn, P.8
Weis, W.I.9
Kobilka, B.K.10
Stevens, R.C.11
-
3
-
-
84865228105
-
New insights for drug design from the X-ray crystallographic structures of GPCRs
-
Jacobson, K. A. and Costanzi, K. (2012) New insights for drug design from the X-ray crystallographic structures of GPCRs. Mol. Pharmacol. 82, 361-371
-
(2012)
Mol. Pharmacol.
, vol.82
, pp. 361-371
-
-
Jacobson, K.A.1
Costanzi, K.2
-
4
-
-
69249146075
-
Engineering G protein-coupled receptors to facilitate their structure determination
-
Tate, C. G. and Schertler, G. F. (2009) Engineering G protein-coupled receptors to facilitate their structure determination. Curr. Opin. Struct. Biol. 19, 386-395
-
(2009)
Curr. Opin. Struct. Biol.
, vol.19
, pp. 386-395
-
-
Tate, C.G.1
Schertler, G.F.2
-
5
-
-
78149501282
-
The properties of thermostabilised G protein-coupled receptors (StaRs) and their use in drug discovery
-
Robertson, N., Jazayeri, A., Errey, J., Baig, A., Hurrell, E., Zhukov, A., Langmead, C. J., Weir, M. and Marshall, F. H. (2010) The properties of thermostabilised G protein-coupled receptors (StaRs) and their use in drug discovery. Neuropharmacology 60, 36-44
-
(2010)
Neuropharmacology
, vol.60
, pp. 36-44
-
-
Robertson, N.1
Jazayeri, A.2
Errey, J.3
Baig, A.4
Hurrell, E.5
Zhukov, A.6
Langmead, C.J.7
Weir, M.8
Marshall, F.H.9
-
6
-
-
47949129742
-
1-adrenergic G protein-coupled receptor
-
1-adrenergic G protein-coupled receptor. Nature 454, 486-491
-
(2008)
Nature
, vol.454
, pp. 486-491
-
-
Warne, A.1
Serrano-Vega, M.J.2
Baker, J.G.3
Moukhametzianov, R.4
Edwards, P.C.5
Henderson, R.6
Leslie, A.G.7
Tate, C.G.8
Schertler, G.F.9
-
7
-
-
79960181417
-
2A receptor in complex with ZM241385 and the xanthines XAC and caffeine
-
2A receptor in complex with ZM241385 and the xanthines XAC and caffeine. Structure 19, 1283-1293
-
(2011)
Structure
, vol.19
, pp. 1283-1293
-
-
Dore, A.S.1
Robertson, N.2
Errey, J.C.3
Ng, I.4
Hollenstein, K.5
Tehan, B.6
Hurrell, E.7
Bennett, K.8
Congreve, M.9
Magnani, F.10
-
8
-
-
79959564813
-
Agonist-bound adenosine A2A receptor structures reveal common features of GPCR activation
-
Lebon, G., Warne, T., Edwards, P. C., Bennett, K., Langmead, C. J., Leslie, A. G. and Tate, C. G. (2011) Agonist-bound adenosine A2A receptor structures reveal common features of GPCR activation. Nature 474, 521-525
-
(2011)
Nature
, vol.474
, pp. 521-525
-
-
Lebon, G.1
Warne, T.2
Edwards, P.C.3
Bennett, K.4
Langmead, C.J.5
Leslie, A.G.6
Tate, C.G.7
-
9
-
-
84867840947
-
Structure of the agonist-bound neurotensin receptor NTS1
-
White, J. F., Noinaj, N., Shibata, Y., Love, J., Kloss, B., Gvozdenovic-Jeremic, J., Shah, P., Shiloach, J., Tate, C. G. and Grisshammer, R. (2012) Structure of the agonist-bound neurotensin receptor NTS1. Nature 490, 508-513
-
(2012)
Nature
, vol.490
, pp. 508-513
-
-
White, J.F.1
Noinaj, N.2
Shibata, Y.3
Love, J.4
Kloss, B.5
Gvozdenovic-Jeremic, J.6
Shah, P.7
Shiloach, J.8
Tate, C.G.9
Grisshammer, R.10
-
10
-
-
84861984672
-
Fusion partner toolchest for the stabilization and crystallization of G protein-coupled receptors
-
Chun, E., Thompson, A. A., Liu, W., Roth, C. B., Griffith, M. T., Katritch, V., Kunken, J., Xu, F., Cherezov, V., Hanson, M. A. and Stevens, R. C. (2012) Fusion partner toolchest for the stabilization and crystallization of G protein-coupled receptors. Structure 20, 967-976
-
(2012)
Structure
, vol.20
, pp. 967-976
-
-
Chun, E.1
Thompson, A.A.2
Liu, W.3
Roth, C.B.4
Griffith, M.T.5
Katritch, V.6
Kunken, J.7
Xu, F.8
Cherezov, V.9
Hanson, M.A.10
Stevens, R.C.11
-
11
-
-
84861961427
-
Structural basis for allosteric regulation of GPCRs by sodium ions
-
Liu, W., Chun, E., Thompson, A. A., Chubukov, P., Xu, F., Katritch, V., Han, G. W., Roth, C. B., Heitman, L. H., Ijzerman, A. P. et al. (2012) Structural basis for allosteric regulation of GPCRs by sodium ions. Science 337, 232-236
-
(2012)
Science
, vol.337
, pp. 232-236
-
-
Liu, W.1
Chun, E.2
Thompson, A.A.3
Chubukov, P.4
Xu, F.5
Katritch, V.6
Han, G.W.7
Roth, C.B.8
Heitman, L.H.9
Ijzerman, A.P.10
-
12
-
-
84861019261
-
Structure of the nociceptin/orphanin FQ receptor in complex with a peptide mimetic
-
Thompson, A. A., Liu, W., Chun, E., Katritch, V., Wu, H., Vardy, E., Huang, X. P., Trapella, C., Guerrini, R., Calo, G. et al. (2012) Structure of the nociceptin/orphanin FQ receptor in complex with a peptide mimetic. Nature 485, 395-399
-
(2012)
Nature
, vol.485
, pp. 395-399
-
-
Thompson, A.A.1
Liu, W.2
Chun, E.3
Katritch, V.4
Wu, H.5
Vardy, E.6
Huang, X.P.7
Trapella, C.8
Guerrini, R.9
Calo, G.10
-
13
-
-
34548826770
-
Expression of recombinant G-protein coupled receptors for structural biology
-
DOI 10.1039/b713558k
-
Mancia, F. and Hendrickson, W. A. (2007) Expression of recombinant G-protein coupled receptors for structural biology. Mol. Biosyst. 3, 723-734 (Pubitemid 47449626)
-
(2007)
Molecular BioSystems
, vol.3
, Issue.10
, pp. 723-734
-
-
Mancia, F.1
Hendrickson, W.A.2
-
14
-
-
33846145129
-
Structural genomics on membrane proteins: Comparison of more than 100 GPCRs in 3 expression systems
-
DOI 10.1007/s10969-006-9011-2
-
Lundstrom, K., Wagner, R., Reinhart, C., Desmyter, A., Cherouati, N., Magnin, T., Zeder-Lutz, G., Courtot, M., Prual, C., Andre, N. et al. (2006) Structural genomics on membrane proteins: comparison of more than 100 GPCRs in 3 expression systems. J. Struct. Funct. Genomics 7, 77-91 (Pubitemid 46085816)
-
(2006)
Journal of Structural and Functional Genomics
, vol.7
, Issue.2
, pp. 77-91
-
-
Lundstrom, K.1
Wagner, R.2
Reinhart, C.3
Desmyter, A.4
Cherouati, N.5
Magnin, T.6
Zeder-Lutz, G.7
Courtot, M.8
Prual, C.9
Andre, N.10
Hassaine, G.11
Michel, H.12
Cambillau, C.13
Pattus, F.14
-
15
-
-
36149001292
-
Glycosylation engineering in yeast: The advent of fully humanized yeast
-
DOI 10.1016/j.copbio.2007.09.001, PII S0958166907001139, Expression Technologies / Tissue and Cell Engineering
-
Hamilton, S. R. and Gerngross, T. U. (2007) Glycosylation engineering in yeast: the advent of fully humanized yeast. Curr. Opin. Biotechnol. 18, 387-392 (Pubitemid 350116586)
-
(2007)
Current Opinion in Biotechnology
, vol.18
, Issue.5
, pp. 387-392
-
-
Hamilton, S.R.1
Gerngross, T.U.2
-
16
-
-
79960070651
-
Structure of the human histamine H1 receptor complex with doxepin
-
Shimamura, T., Shiroishi, M., Weyand, S., Tsujimoto, H., Winter, G., Katritch, V., Abagyan, R., Cherezov, V., Liu, W., Han, G. W. et al. (2011) Structure of the human histamine H1 receptor complex with doxepin. Nature 475, 65-70
-
(2011)
Nature
, vol.475
, pp. 65-70
-
-
Shimamura, T.1
Shiroishi, M.2
Weyand, S.3
Tsujimoto, H.4
Winter, G.5
Katritch, V.6
Abagyan, R.7
Cherezov, V.8
Liu, W.9
Han, G.W.10
-
17
-
-
26044438731
-
Characterization of 16 human G protein-coupled receptors expressed in baculovirus-infected insect cells
-
DOI 10.1016/j.pep.2005.04.016, PII S1046592805001543
-
Akermoun, M., Koglin, M., Zvalova-Iooss, D., Folschweiller, N., Dowell, S. J. and Gearing, K. L. (2005) Characterization of 16 human G protein-coupled receptors expressed in baculovirus-infected insect cells. Protein Expression Purif. 44, 65-74 (Pubitemid 41405937)
-
(2005)
Protein Expression and Purification
, vol.44
, Issue.1
, pp. 65-74
-
-
Akermoun, M.1
Koglin, M.2
Zvalova-Iooss, D.3
Folschweiller, N.4
Dowell, S.J.5
Gearing, K.L.6
-
18
-
-
0037450576
-
Expression and purification of truncated, non-glycosylated turkey beta-adrenergic receptors for crystallization
-
DOI 10.1016/S0005-2736(02)00716-2
-
Warne, T., Chirnside, J. and Schertler, G. F. (2003) Expression and purification of truncated, non-glycosylated turkey β-adrenergic receptors for crystallization. Biochim. Biophys. Acta 1610, 133-140 (Pubitemid 36174004)
-
(2003)
Biochimica et Biophysica Acta - Biomembranes
, vol.1610
, Issue.1
, pp. 133-140
-
-
Warne, T.1
Chirnside, J.2
Schertler, G.F.X.3
-
19
-
-
0037436330
-
Critical role of N-terminal N-glycosylation for proper folding of the human formyl peptide receptor
-
DOI 10.1016/S0006-291X(03)00023-8
-
Wenzel-Seifert, K. and Seifert, R. (2003) Critical role of N-terminal N-glycosylation for proper folding of the human formyl peptide receptor. Biochem. Biophys. Res. Comm. 301, 693-698 (Pubitemid 36277662)
-
(2003)
Biochemical and Biophysical Research Communications
, vol.301
, Issue.3
, pp. 693-698
-
-
Wenzel-Seifert, K.1
Seifert, R.2
-
20
-
-
0028879530
-
Expression of the human oxytocin receptor in baculovirus-infected insect cells: High-affinity binding is induced by a cholesterol-cyclodextrin complex
-
Gimpl, G., Klein, U., Reilander, H. and Fahrenholz, F. (1995) Expression of the human oxytocin receptor in baculovirus-infected insect cells: high-affinity binding is induced by a cholesterol-cyclodextrin complex. Biochemistry 34, 13794-13801
-
(1995)
Biochemistry
, vol.34
, pp. 13794-13801
-
-
Gimpl, G.1
Klein, U.2
Reilander, H.3
Fahrenholz, F.4
-
21
-
-
84863115467
-
Structure and dynamics of the M3 muscarinic acetylcholine receptor
-
Kruse, A. C., Hu, J., Pan, A. C., Arlow, D. H., Rosenbaum, D. M., Rosemond, E., Green, H. F., Liu, T., Chae, P. S., Dror, R. O. et al. (2012) Structure and dynamics of the M3 muscarinic acetylcholine receptor. Nature 482, 552-556
-
(2012)
Nature
, vol.482
, pp. 552-556
-
-
Kruse, A.C.1
Hu, J.2
Pan, A.C.3
Arlow, D.H.4
Rosenbaum, D.M.5
Rosemond, E.6
Green, H.F.7
Liu, T.8
Chae, P.S.9
Dror, R.O.10
-
22
-
-
85027927015
-
Structures of the CXCR4 chemokine GPCR with small-molecule and cyclic peptide antagonists
-
Wu, B., Chien, E. Y., Mol, C. D., Fenalti, G., Liu, W., Katritch, V., Abagyan, R., Brooun, A., Wells, P., Bi, F. C. et al. (2010) Structures of the CXCR4 chemokine GPCR with small-molecule and cyclic peptide antagonists. Science 330, 1066-1071
-
(2010)
Science
, vol.330
, pp. 1066-1071
-
-
Wu, B.1
Chien, E.Y.2
Mol, C.D.3
Fenalti, G.4
Liu, W.5
Katritch, V.6
Abagyan, R.7
Brooun, A.8
Wells, P.9
Bi, F.C.10
-
23
-
-
84857254248
-
Crystal structure of a lipid G protein-coupled receptor
-
Hanson, M. A., Roth, C. B., Jo, E., Griffith, M. T., Scott, F. L., Reinhart, G., Desale, H., Clemons, B., Cahalan, S. M., Schuerer, S. C. et al. (2012) Crystal structure of a lipid G protein-coupled receptor. Science 335, 851-855
-
(2012)
Science
, vol.335
, pp. 851-855
-
-
Hanson, M.A.1
Roth, C.B.2
Jo, E.3
Griffith, M.T.4
Scott, F.L.5
Reinhart, G.6
Desale, H.7
Clemons, B.8
Cahalan, S.M.9
Schuerer, S.C.10
-
24
-
-
78449305788
-
Structure of the human dopamine D3 receptor in complex with a D2/D3 selective antagonist
-
Chien, E. Y., Liu, W., Zhao, Q., Katritch, V., Han, G. W., Hanson, M. A., Shi, L., Newman, A. H., Javitch, J. A., Cherezov, V. and Stevens, R. C. (2010) Structure of the human dopamine D3 receptor in complex with a D2/D3 selective antagonist. Science 330, 1091-1095
-
(2010)
Science
, vol.330
, pp. 1091-1095
-
-
Chien, E.Y.1
Liu, W.2
Zhao, Q.3
Katritch, V.4
Han, G.W.5
Hanson, M.A.6
Shi, L.7
Newman, A.H.8
Javitch, J.A.9
Cherezov, V.10
Stevens, R.C.11
-
25
-
-
4143053500
-
Optimization of protein production in mammalian cells with a coexpressed fluorescent marker
-
DOI 10.1016/j.str.2004.06.012, PII S0969212604002400
-
Mancia, F., Patel, S. D., Rajala, M. W., Scherer, P. E., Nemes, A., Schieren, I., Hendrickson, W. A. and Shapiro, L. (2004) Optimization of protein production in mammalian cells with a coexpressed fluorescent marker. Structure 12, 1355-1360 (Pubitemid 39092080)
-
(2004)
Structure
, vol.12
, Issue.8
, pp. 1355-1360
-
-
Mancia, F.1
Patel, S.D.2
Rajala, M.W.3
Scherer, P.E.4
Nemes, A.5
Schieren, I.6
Hendrickson, W.A.7
Shapiro, L.8
-
26
-
-
34548529916
-
Crystal Structure of a Thermally Stable Rhodopsin Mutant
-
DOI 10.1016/j.jmb.2007.03.007, PII S0022283607003361
-
Standfuss, J., Xie, G., Edwards, P. C., Burghammer, M., Oprian, D. D. and Schertler, G. F. (2007) Crystal structure of a thermally stable rhodopsin mutant. J. Mol. Biol. 372, 1179-1188 (Pubitemid 47381449)
-
(2007)
Journal of Molecular Biology
, vol.372
, Issue.5
, pp. 1179-1188
-
-
Standfuss, J.1
Xie, G.2
Edwards, P.C.3
Burghammer, M.4
Oprian, D.D.5
Schertler, G.F.X.6
-
27
-
-
84855990615
-
Stabilized G protein binding site in the structure of constitutively active metarhodopsin-II
-
Deupi, X., Edwards, P., Singhal, A., Nickle, B., Oprian, D., Schertler, G. and Standfuss, J. (2012) Stabilized G protein binding site in the structure of constitutively active metarhodopsin-II. Proc. Natl. Acad. Sci. U. S. A. 109, 119-124
-
(2012)
Proc. Natl. Acad. Sci. U. S. A.
, vol.109
, pp. 119-124
-
-
Deupi, X.1
Edwards, P.2
Singhal, A.3
Nickle, B.4
Oprian, D.5
Schertler, G.6
Standfuss, J.7
-
28
-
-
56749103466
-
2A adenosine receptor bound to an antagonist
-
2A adenosine receptor bound to an antagonist. Science 322, 1211-1217
-
(2008)
Science
, vol.322
, pp. 1211-1217
-
-
Jaakola, V.P.1
Griffith, M.T.2
Hanson, M.A.3
Cherezov, V.4
Chien, E.Y.5
Lane, J.R.6
Ijzerman, A.P.7
Stevens, R.C.8
-
29
-
-
84861096654
-
Crystal structure of the μ-opioid receptor bound to a morphinan antagonist
-
Manglik, A., Kruse, A. C., Kobilka, T. S., Thian, F. S., Mathiesen, J. M., Sunahara, R. K., Pardo, L., Weis, W. I., Kobilka, B. K. and Granier, S. (2012) Crystal structure of the μ-opioid receptor bound to a morphinan antagonist. Nature 485, 321-326
-
(2012)
Nature
, vol.485
, pp. 321-326
-
-
Manglik, A.1
Kruse, A.C.2
Kobilka, T.S.3
Thian, F.S.4
Mathiesen, J.M.5
Sunahara, R.K.6
Pardo, L.7
Weis, W.I.8
Kobilka, B.K.9
Granier, S.10
-
30
-
-
36248970132
-
2 adrenergic G-protein-coupled receptor
-
DOI 10.1038/nature06325, PII NATURE06325
-
2 adrenergic G-protein-coupled receptor. Nature 450, 383-387 (Pubitemid 350126755)
-
(2007)
Nature
, vol.450
, Issue.7168
, pp. 383-387
-
-
Rasmussen, S.G.F.1
Choi, H.-J.2
Rosenbaum, D.M.3
Kobilka, T.S.4
Thian, F.S.5
Edwards, P.C.6
Burghammer, M.7
Ratnala, V.R.P.8
Sanishvili, R.9
Fischetti, R.F.10
Schertler, G.F.X.11
Weis, W.I.12
Kobilka, B.K.13
-
31
-
-
84861075468
-
Structure of the δ-opioid receptor bound to naltrindole
-
Granier, S., Manglik, A., Kruse, A. C., Kobilka, T. S., Thian, F. S., Weis, W. I. and Kobilka, B. K. (2012) Structure of the δ-opioid receptor bound to naltrindole. Nature 485, 400-404
-
(2012)
Nature
, vol.485
, pp. 400-404
-
-
Granier, S.1
Manglik, A.2
Kruse, A.C.3
Kobilka, T.S.4
Thian, F.S.5
Weis, W.I.6
Kobilka, B.K.7
-
32
-
-
33751019133
-
Improvements in G protein-coupled receptor purification yield light stable rhodopsin crystals
-
DOI 10.1016/j.jsb.2006.05.003, PII S1047847706001675
-
Salom, D., Le Trong, I., Pohl, E., Ballesteros, J. A., Stenkamp, R. E., Palczewski, K. and Lodowski, D. T. (2006) Improvements in G protein-coupled receptor purification yield light stable rhodopsin crystals. J. Struct. Biol. 156, 497-504 (Pubitemid 44751468)
-
(2006)
Journal of Structural Biology
, vol.156
, Issue.3
, pp. 497-504
-
-
Salom, D.1
Le Trong, I.2
Pohl, E.3
Ballesteros, J.A.4
Stenkamp, R.E.5
Palczewski, K.6
Lodowski, D.T.7
-
33
-
-
84862777405
-
Structure of the human M2 muscarinic acetylcholine receptor bound to an antagonist
-
Haga, K., Kruse, A. C., Asada, H., Yurugi-Kobayashi, T., Shiroishi, M., Zhang, C., Weis, W. I., Okada, T., Kobilka, B. K., Haga, T. and Kobayashi, T. (2012) Structure of the human M2 muscarinic acetylcholine receptor bound to an antagonist. Nature 482, 547-551
-
(2012)
Nature
, vol.482
, pp. 547-551
-
-
Haga, K.1
Kruse, A.C.2
Asada, H.3
Yurugi-Kobayashi, T.4
Shiroishi, M.5
Zhang, C.6
Weis, W.I.7
Okada, T.8
Kobilka, B.K.9
Haga, T.10
Kobayashi, T.11
-
34
-
-
0020653760
-
Purification of muscarinic acetylcholine receptors by affinity chromatography
-
Andre, C, De Backer, J. P., Guillet, J. C., Vanderheyden, P., Vauquelin, G. and Strosberg, A. D. (1983) Purification of muscarinic acetylcholine receptors by affinity chromatography. EMBOJ. 2, 499-504
-
(1983)
EMBOJ.
, vol.2
, pp. 499-504
-
-
Andre, C.1
De Backer, J.P.2
Guillet, J.C.3
Vanderheyden, P.4
Vauquelin, G.5
Strosberg, A.D.6
-
35
-
-
41549121540
-
Analysis of a G protein-coupled receptor for neurotensin by liquid chromatography-electrospray ionization-mass spectrometry
-
Ho, J. T. C., White, J. F., Grisshammer, R. and Hess, S. (2008) Analysis of a G protein-coupled receptor for neurotensin by liquid chromatography- electrospray ionization-mass spectrometry. Anal. Biochem. 376, 13-24
-
(2008)
Anal. Biochem.
, vol.376
, pp. 13-24
-
-
Ho, J.T.C.1
White, J.F.2
Grisshammer, R.3
Hess, S.4
-
36
-
-
40049099087
-
Microscale fluorescent thermal stability assay for membrane proteins
-
DOI 10.1016/j.str.2008.02.004, PII S0969212608000609
-
Alexandrov, A. I., Mileni, M., Chien, E. Y., Hanson, M. A. and Stevens, R. C. (2008) Microscale fluorescent thermal stability assay for membrane proteins. Structure 16, 351-359 (Pubitemid 351324124)
-
(2008)
Structure
, vol.16
, Issue.3
, pp. 351-359
-
-
Alexandrov, A.I.1
Mileni, M.2
Chien, E.Y.T.3
Hanson, M.A.4
Stevens, R.C.5
-
38
-
-
71549126621
-
Automated large-scale purification of a recombinant G-protein-coupled neurotensin receptor
-
White, J. F. and Grisshammer, R. (2007) Automated large-scale purification of a recombinant G-protein-coupled neurotensin receptor. Curr. Protoc. Protein Sci. 47, 6.8.1-6.8.31
-
(2007)
Curr. Protoc. Protein Sci.
, vol.47
, pp. 681-6831
-
-
White, J.F.1
Grisshammer, R.2
-
39
-
-
9944262886
-
A colorimetric determination for glycosidic and bile salt-based detergents: Applications in membrane protein research
-
DOI 10.1016/j.ab.2004.09.040, PII S000326970400795X
-
Urbani, A. and Warne, T. (2005) A colorimetric determination for glycosidic and bile salt-based detergents: applications in membrane protein research. Anal. Biochem. 336, 117-124 (Pubitemid 39593507)
-
(2005)
Analytical Biochemistry
, vol.336
, Issue.1
, pp. 117-124
-
-
Urbani, A.1
Warne, T.2
-
40
-
-
6344227960
-
Crystals of native and modified bovine rhodopsins and their heavy atom derivatives
-
DOI 10.1016/j.jmb.2004.08.089, PII S0022283604010897
-
Edwards, P. C., Li, J., Burghammer, M., McDowell, J. H., Villa, C, Hargrave, P. A. and Schertler, G. F. (2004) Crystals of native and modified bovine rhodopsins and their heavy atom derivatives. J. Mol. Biol. 343, 1439-1450 (Pubitemid 39387835)
-
(2004)
Journal of Molecular Biology
, vol.343
, Issue.5
, pp. 1439-1450
-
-
Edwards, P.C.1
Li, J.2
Burghammer, M.3
Hugh McDowell, J.4
Villa, C.5
Hargrave, P.A.6
Schertler, G.F.X.7
-
41
-
-
78651405537
-
1-adrenergic receptor
-
1-adrenergic receptor. Nature 469, 241-244
-
(2011)
Nature
, vol.469
, pp. 241-244
-
-
Warne, T.1
Moukhametzianov, R.2
Baker, J.G.3
Nehme, R.4
Edwards, P.C.5
Leslie, A.G.6
Schertler, G.F.7
Tate, C.G.8
-
42
-
-
84862776818
-
G-protein-coupled receptor inactivation by an allosteric inverse-agonist antibody
-
Hino, T., Arakawa, T., Iwanari, H., Yurugi-Kobayashi, T., Ikeda-Suno, C., Nakada-Nakura, Y., Kusano-Arai, O., Weyand, S., Shimamura, T., Nomura, N. et al. (2012) G-protein-coupled receptor inactivation by an allosteric inverse-agonist antibody. Nature 482, 237-240
-
(2012)
Nature
, vol.482
, pp. 237-240
-
-
Hino, T.1
Arakawa, T.2
Iwanari, H.3
Yurugi-Kobayashi, T.4
Ikeda-Suno, C.5
Nakada-Nakura, Y.6
Kusano-Arai, O.7
Weyand, S.8
Shimamura, T.9
Nomura, N.10
-
43
-
-
36448978229
-
2-adrenergic receptor function
-
DOI 10.1126/science.1150609
-
2-adrenergic receptor function. Science 318, 1266-1273 (Pubitemid 350172885)
-
(2007)
Science
, vol.318
, Issue.5854
, pp. 1266-1273
-
-
Rosenbaum, D.M.1
Cherezov, V.2
Hanson, M.A.3
Rasmussen, S.G.F.4
Foon, S.T.5
Kobilka, T.S.6
Choi, H.-J.7
Yao, X.-J.8
Weis, W.I.9
Stevens, R.C.10
Kobilka, B.K.11
-
44
-
-
84862777742
-
Structure of the human κ-opioid receptor in complex with JDTic
-
Wu, H., Wacker, D., Mileni, M., Katritch, V., Han, G. W., Vardy, E., Liu, W., Thompson, A. A., Huang, X. P., Carroll, F. I. et al. (2012) Structure of the human κ-opioid receptor in complex with JDTic. Nature 485, 327-332
-
(2012)
Nature
, vol.485
, pp. 327-332
-
-
Wu, H.1
Wacker, D.2
Mileni, M.3
Katritch, V.4
Han, G.W.5
Vardy, E.6
Liu, W.7
Thompson, A.A.8
Huang, X.P.9
Carroll, F.I.10
-
45
-
-
80053357815
-
2 adrenergic receptor
-
2 adrenergic receptor. Nature 477, 611-615
-
(2011)
Nature
, vol.477
, pp. 611-615
-
-
Chung, K.Y.1
Rasmussen, S.G.2
Liu, T.3
Li, S.4
De Vree, B.T.5
Chae, P.S.6
Calinski, D.7
Kobilka, B.K.8
Woods Jr., V.L.9
Sunahara, R.K.10
-
46
-
-
78649693871
-
Maltose-neopentyl glycol (MNG) amphiphiles for solubilization, stabilization and crystallization of membrane proteins
-
Chae, P. S., Rasmussen, S. G., Rana, R. R., Gotfryd, K., Chandra, R., Goren, M. A., Kruse, A. C., Nurva, S., Loland, C. J., Pierre, Y. et al. (2010) Maltose-neopentyl glycol (MNG) amphiphiles for solubilization, stabilization and crystallization of membrane proteins. Nat. Methods 7, 1003-1008
-
(2010)
Nat. Methods
, vol.7
, pp. 1003-1008
-
-
Chae, P.S.1
Rasmussen, S.G.2
Rana, R.R.3
Gotfryd, K.4
Chandra, R.5
Goren, M.A.6
Kruse, A.C.7
Nurva, S.8
Loland, C.J.9
Pierre, Y.10
-
47
-
-
78651411166
-
2 adrenoceptor
-
2 adrenoceptor. Nature 469, 175-180
-
(2011)
Nature
, vol.469
, pp. 175-180
-
-
Rasmussen, S.G.1
Choi, H.J.2
Fung, J.J.3
Pardon, E.4
Casarosa, P.5
Chae, P.S.6
Devree, B.T.7
Rosenbaum, D.M.8
Thian, F.S.9
Kobilka, T.S.10
-
48
-
-
77953286311
-
Structure determination of the seven-helix transmembrane receptor sensory rhodopsin II by solution NMR spectroscopy
-
Gautier, A., Mott, H. R., Bostock, M. J., Kirkpatrick, J. P. and Nietlispach, D. (2010) Structure determination of the seven-helix transmembrane receptor sensory rhodopsin II by solution NMR spectroscopy. Nat. Struct. Mol. Biol. 17, 768-774
-
(2010)
Nat. Struct. Mol. Biol.
, vol.17
, pp. 768-774
-
-
Gautier, A.1
Mott, H.R.2
Bostock, M.J.3
Kirkpatrick, J.P.4
Nietlispach, D.5
-
49
-
-
79960156006
-
Biophysical mapping of the adenosine A2A receptor
-
Zhukov, A., Andrews, S. P., Errey, J. C., Robertson, N., Tehan, B., Mason, J. S., Marshall, F. H., Weir, M. and Congreve, M. (2011) Biophysical mapping of the adenosine A2A receptor. J. Med. Chem. 54, 4312-4323
-
(2011)
J. Med. Chem.
, vol.54
, pp. 4312-4323
-
-
Zhukov, A.1
Andrews, S.P.2
Errey, J.C.3
Robertson, N.4
Tehan, B.5
Mason, J.S.6
Marshall, F.H.7
Weir, M.8
Congreve, M.9
-
50
-
-
84858034356
-
Discovery of 1, 2, 4-triazine derivatives as adenosine A2A antagonists using structure based drug design
-
Congreve, M., Andrews, S. P., Doré, A. S., Hollenstein, K., Hurrell, E., Langmead, C. J., Mason, J. S., Ng, I. W., Tehan, B., Zhukov, A. et al. (2012) Discovery of 1, 2, 4-triazine derivatives as adenosine A2A antagonists using structure based drug design. J. Med. Chem. 55, 1898-1903
-
(2012)
J. Med. Chem.
, vol.55
, pp. 1898-1903
-
-
Congreve, M.1
Andrews, S.P.2
Doré, A.S.3
Hollenstein, K.4
Hurrell, E.5
Langmead, C.J.6
Mason, J.S.7
Ng, I.W.8
Tehan, B.9
Zhukov, A.10
|