-
1
-
-
33748931457
-
Central nervous system control of food intake and body weight
-
16988703 10.1038/nature05026 1:CAS:528:DC%2BD28Xpslalu7c%3D
-
Morton GJ, Cummings DE, Baskin DG, Barsh GS, Schwartz MW (2006) Central nervous system control of food intake and body weight. Nature 443(7109):289-295
-
(2006)
Nature
, vol.443
, Issue.7109
, pp. 289-295
-
-
Morton, G.J.1
Cummings, D.E.2
Baskin, D.G.3
Barsh, G.S.4
Schwartz, M.W.5
-
2
-
-
0033082380
-
From lesions to leptin: Hypothalamic control of food intake and body weight
-
10069329 10.1016/S0896-6273(00)81084-3 1:CAS:528:DyaK1MXhs12lu7c%3D
-
Elmquist JK, Elias CF, Saper CB (1999) From lesions to leptin: hypothalamic control of food intake and body weight. Neuron 22(2):221-232
-
(1999)
Neuron
, vol.22
, Issue.2
, pp. 221-232
-
-
Elmquist, J.K.1
Elias, C.F.2
Saper, C.B.3
-
3
-
-
0028139089
-
Positional cloning of the mouse obese gene and its human homologue
-
7984236 10.1038/372425a0 1:CAS:528:DyaK2MXisVGqsbs%3D
-
Zhang Y, Proenca R, Maffei M, Barone M, Leopold L, Friedman JM (1994) Positional cloning of the mouse obese gene and its human homologue. Nature 372(6505):425-432
-
(1994)
Nature
, vol.372
, Issue.6505
, pp. 425-432
-
-
Zhang, Y.1
Proenca, R.2
Maffei, M.3
Barone, M.4
Leopold, L.5
Friedman, J.M.6
-
4
-
-
0037122766
-
Leptin stimulates fatty-acid oxidation by activating AMP-activated protein kinase
-
11797013 10.1038/415339a 1:CAS:528:DC%2BD38Xptlamtw%3D%3D
-
Minokoshi Y, Kim YB, Peroni OD, Fryer LG, Muller C, Carling D, Kahn BB (2002) Leptin stimulates fatty-acid oxidation by activating AMP-activated protein kinase. Nature 415(6869):339-343
-
(2002)
Nature
, vol.415
, Issue.6869
, pp. 339-343
-
-
Minokoshi, Y.1
Kim, Y.B.2
Peroni, O.D.3
Fryer, L.G.4
Muller, C.5
Carling, D.6
Kahn, B.B.7
-
5
-
-
36048955043
-
The central melanocortin system directly controls peripheral lipid metabolism
-
17885689 10.1172/JCI31743 1:CAS:528:DC%2BD2sXht12is7%2FK
-
Nogueiras R, Wiedmer P, Perez-Tilve D, Veyrat-Durebex C, Keogh JM, Sutton GM, Pfluger PT, Castaneda TR, Neschen S, Hofmann SM, Howles PN, Morgan DA, Benoit SC, Szanto I, Schrott B, Schurmann A, Joost HG, Hammond C, Hui DY, Woods SC, Rahmouni K, Butler AA, Farooqi IS, O'Rahilly S, Rohner-Jeanrenaud F, Tschop MH (2007) The central melanocortin system directly controls peripheral lipid metabolism. J Clin Invest 117(11):3475-3488
-
(2007)
J Clin Invest
, vol.117
, Issue.11
, pp. 3475-3488
-
-
Nogueiras, R.1
Wiedmer, P.2
Perez-Tilve, D.3
Veyrat-Durebex, C.4
Keogh, J.M.5
Sutton, G.M.6
Pfluger, P.T.7
Castaneda, T.R.8
Neschen, S.9
Hofmann, S.M.10
Howles, P.N.11
Morgan, D.A.12
Benoit, S.C.13
Szanto, I.14
Schrott, B.15
Schurmann, A.16
Joost, H.G.17
Hammond, C.18
Hui, D.Y.19
Woods, S.C.20
Rahmouni, K.21
Butler, A.A.22
Farooqi, I.S.23
O'Rahilly, S.24
Rohner-Jeanrenaud, F.25
Tschop, M.H.26
more..
-
6
-
-
82955239851
-
Impairment of central leptin-mediated PI3 K signaling manifested as hepatic steatosis independent of hyperphagia and obesity
-
22152304 10.1016/j.cmet.2011.11.001 1:CAS:528:DC%2BC3MXhs1Sktr%2FI
-
Warne JP, Alemi F, Reed AS, Varonin JM, Chan H, Piper ML, Mullin ME, Myers MG Jr, Corvera CU, Xu AW (2011) Impairment of central leptin-mediated PI3 K signaling manifested as hepatic steatosis independent of hyperphagia and obesity. Cell Metab 14(6):791-803
-
(2011)
Cell Metab
, vol.14
, Issue.6
, pp. 791-803
-
-
Warne, J.P.1
Alemi, F.2
Reed, A.S.3
Varonin, J.M.4
Chan, H.5
Piper, M.L.6
Mullin, M.E.7
Myers, Jr.M.G.8
Corvera, C.U.9
Xu, A.W.10
-
7
-
-
36448941416
-
Enhanced leptin-stimulated Pi3 k activation in the CNS promotes white adipose tissue transdifferentiation
-
18054313 10.1016/j.cmet.2007.10.012 1:CAS:528:DC%2BD2sXhsVektb7K
-
Plum L, Rother E, Munzberg H, Wunderlich FT, Morgan DA, Hampel B, Shanabrough M, Janoschek R, Konner AC, Alber J, Suzuki A, Krone W, Horvath TL, Rahmouni K, Bruning JC (2007) Enhanced leptin-stimulated Pi3 k activation in the CNS promotes white adipose tissue transdifferentiation. Cell Metab 6(6):431-445
-
(2007)
Cell Metab
, vol.6
, Issue.6
, pp. 431-445
-
-
Plum, L.1
Rother, E.2
Munzberg, H.3
Wunderlich, F.T.4
Morgan, D.A.5
Hampel, B.6
Shanabrough, M.7
Janoschek, R.8
Konner, A.C.9
Alber, J.10
Suzuki, A.11
Krone, W.12
Horvath, T.L.13
Rahmouni, K.14
Bruning, J.C.15
-
8
-
-
77956644726
-
SIRT1 deacetylase in POMC neurons is required for homeostatic defenses against diet-induced obesity
-
20620997 10.1016/j.cmet.2010.05.010 1:CAS:528:DC%2BC3cXptFKqs7w%3D
-
Ramadori G, Fujikawa T, Fukuda M, Anderson J, Morgan DA, Mostoslavsky R, Stuart RC, Perello M, Vianna CR, Nillni EA, Rahmouni K, Coppari R (2010) SIRT1 deacetylase in POMC neurons is required for homeostatic defenses against diet-induced obesity. Cell Metab 12(1):78-87
-
(2010)
Cell Metab
, vol.12
, Issue.1
, pp. 78-87
-
-
Ramadori, G.1
Fujikawa, T.2
Fukuda, M.3
Anderson, J.4
Morgan, D.A.5
Mostoslavsky, R.6
Stuart, R.C.7
Perello, M.8
Vianna, C.R.9
Nillni, E.A.10
Rahmouni, K.11
Coppari, R.12
-
9
-
-
0036550064
-
Cardiovascular and sympathetic effects of leptin
-
11884267 10.1007/s11906-002-0036-z
-
Rahmouni K, Haynes WG, Mark AL (2002) Cardiovascular and sympathetic effects of leptin. Curr Hypertens Rep 4(2):119-125
-
(2002)
Curr Hypertens Rep
, vol.4
, Issue.2
, pp. 119-125
-
-
Rahmouni, K.1
Haynes, W.G.2
Mark, A.L.3
-
10
-
-
15844384047
-
Leptin regulation of bone resorption by the sympathetic nervous system and CART
-
15724149 10.1038/nature03398 1:CAS:528:DC%2BD2MXisFeit70%3D
-
Elefteriou F, Ahn JD, Takeda S, Starbuck M, Yang X, Liu X, Kondo H, Richards WG, Bannon TW, Noda M, Clement K, Vaisse C, Karsenty G (2005) Leptin regulation of bone resorption by the sympathetic nervous system and CART. Nature 434(7032):514-520
-
(2005)
Nature
, vol.434
, Issue.7032
, pp. 514-520
-
-
Elefteriou, F.1
Ahn, J.D.2
Takeda, S.3
Starbuck, M.4
Yang, X.5
Liu, X.6
Kondo, H.7
Richards, W.G.8
Bannon, T.W.9
Noda, M.10
Clement, K.11
Vaisse, C.12
Karsenty, G.13
-
11
-
-
41849134729
-
Leptin resistance contributes to obesity and hypertension in mouse models of Bardet-Biedl syndrome
-
18317593 10.1172/JCI32357 1:CAS:528:DC%2BD1cXkt1Cnurg%3D
-
Rahmouni K, Fath MA, Seo S, Thedens DR, Berry CJ, Weiss R, Nishimura DY, Sheffield VC (2008) Leptin resistance contributes to obesity and hypertension in mouse models of Bardet-Biedl syndrome. J Clin Invest 118(4):1458-1467
-
(2008)
J Clin Invest
, vol.118
, Issue.4
, pp. 1458-1467
-
-
Rahmouni, K.1
Fath, M.A.2
Seo, S.3
Thedens, D.R.4
Berry, C.J.5
Weiss, R.6
Nishimura, D.Y.7
Sheffield, V.C.8
-
12
-
-
0036066483
-
The concept of selective leptin resistance: Evidence from agouti yellow obese mice
-
11812752 10.2337/diabetes.51.2.439 1:CAS:528:DC%2BD38XhtVaqu7s%3D
-
Correia ML, Haynes WG, Rahmouni K, Morgan DA, Sivitz WI, Mark AL (2002) The concept of selective leptin resistance: evidence from agouti yellow obese mice. Diabetes 51(2):439-442
-
(2002)
Diabetes
, vol.51
, Issue.2
, pp. 439-442
-
-
Correia, M.L.1
Haynes, W.G.2
Rahmouni, K.3
Morgan, D.A.4
Sivitz, W.I.5
Mark, A.L.6
-
13
-
-
77950507182
-
Exposure to a high-fat diet alters leptin sensitivity and elevates renal sympathetic nerve activity and arterial pressure in rabbits
-
20194306 10.1161/HYPERTENSIONAHA.109.141119 1:CAS:528: DC%2BC3cXktFOrsr4%3D
-
Prior LJ, Eikelis N, Armitage JA, Davern PJ, Burke SL, Montani JP, Barzel B, Head GA (2010) Exposure to a high-fat diet alters leptin sensitivity and elevates renal sympathetic nerve activity and arterial pressure in rabbits. Hypertension 55(4):862-868
-
(2010)
Hypertension
, vol.55
, Issue.4
, pp. 862-868
-
-
Prior, L.J.1
Eikelis, N.2
Armitage, J.A.3
Davern, P.J.4
Burke, S.L.5
Montani, J.P.6
Barzel, B.7
Head, G.A.8
-
14
-
-
21344432100
-
Role of selective leptin resistance in diet-induced obesity hypertension
-
15983201 10.2337/diabetes.54.7.2012 1:CAS:528:DC%2BD2MXmtVelsLc%3D
-
Rahmouni K, Morgan DA, Morgan GM, Mark AL, Haynes WG (2005) Role of selective leptin resistance in diet-induced obesity hypertension. Diabetes 54(7):2012-2018
-
(2005)
Diabetes
, vol.54
, Issue.7
, pp. 2012-2018
-
-
Rahmouni, K.1
Morgan, D.A.2
Morgan, G.M.3
Mark, A.L.4
Haynes, W.G.5
-
15
-
-
79953213613
-
Cardiovascular and sympathetic effects of disrupting tyrosine 985 of the leptin receptor
-
21263121 10.1161/HYPERTENSIONAHA.110.166538 1:CAS:528: DC%2BC3MXitVOgt7w%3D
-
Harlan SM, Morgan DA, Dellsperger DJ, Myers MG Jr, Mark AL, Rahmouni K (2011) Cardiovascular and sympathetic effects of disrupting tyrosine 985 of the leptin receptor. Hypertension 57(3):627-632
-
(2011)
Hypertension
, vol.57
, Issue.3
, pp. 627-632
-
-
Harlan, S.M.1
Morgan, D.A.2
Dellsperger, D.J.3
Myers, Jr.M.G.4
Mark, A.L.5
Rahmouni, K.6
-
16
-
-
0030774228
-
Regional sympathetic nervous activity and oxygen consumption in obese normotensive human subjects
-
9396437 10.1161/01.CIR.96.10.3423 1:STN:280:DyaK1c%2FlslWhsQ%3D%3D
-
Vaz M, Jennings G, Turner A, Cox H, Lambert G, Esler M (1997) Regional sympathetic nervous activity and oxygen consumption in obese normotensive human subjects. Circulation 96(10):3423-3429
-
(1997)
Circulation
, vol.96
, Issue.10
, pp. 3423-3429
-
-
Vaz, M.1
Jennings, G.2
Turner, A.3
Cox, H.4
Lambert, G.5
Esler, M.6
-
17
-
-
0038334588
-
Interactions between leptin and the human sympathetic nervous system
-
12668587 10.1161/01.HYP.0000066289.17754.49 1:CAS:528: DC%2BD3sXjtFWqtLo%3D
-
Eikelis N, Schlaich M, Aggarwal A, Kaye D, Esler M (2003) Interactions between leptin and the human sympathetic nervous system. Hypertension 41(5):1072-1079
-
(2003)
Hypertension
, vol.41
, Issue.5
, pp. 1072-1079
-
-
Eikelis, N.1
Schlaich, M.2
Aggarwal, A.3
Kaye, D.4
Esler, M.5
-
18
-
-
0031895877
-
Increased expression of mRNA for the long form of the leptin receptor in the hypothalamus is associated with leptin hypersensitivity and fasting
-
9568684 10.2337/diabetes.47.4.538 1:CAS:528:DyaK1cXit1Gns78%3D
-
Baskin DG, Seeley RJ, Kuijper JL, Lok S, Weigle DS, Erickson JC, Palmiter RD, Schwartz MW (1998) Increased expression of mRNA for the long form of the leptin receptor in the hypothalamus is associated with leptin hypersensitivity and fasting. Diabetes 47(4):538-543
-
(1998)
Diabetes
, vol.47
, Issue.4
, pp. 538-543
-
-
Baskin, D.G.1
Seeley, R.J.2
Kuijper, J.L.3
Lok, S.4
Weigle, D.S.5
Erickson, J.C.6
Palmiter, R.D.7
Schwartz, M.W.8
-
19
-
-
78049297525
-
Outstanding Scientific Achievement Award Lecture 2010: Deconstructing leptin: From signals to circuits
-
20980468 10.2337/db10-1118 1:CAS:528:DC%2BC3cXhsV2nsLfE
-
Myers MG Jr (2010) Outstanding Scientific Achievement Award Lecture 2010: deconstructing leptin: from signals to circuits. Diabetes 59(11):2708-2714
-
(2010)
Diabetes
, vol.59
, Issue.11
, pp. 2708-2714
-
-
Myers, Jr.M.G.1
-
20
-
-
17844389670
-
The hypothalamic arcuate nucleus: A key site for mediating leptin's effects on glucose homeostasis and locomotor activity
-
16054045 10.1016/j.cmet.2004.12.004 1:CAS:528:DC%2BD2MXhtlaqs7o%3D
-
Coppari R, Ichinose M, Lee CE, Pullen AE, Kenny CD, McGovern RA, Tang V, Liu SM, Ludwig T, Chua SC Jr, Lowell BB, Elmquist JK (2005) The hypothalamic arcuate nucleus: a key site for mediating leptin's effects on glucose homeostasis and locomotor activity. Cell Metab 1(1):63-72
-
(2005)
Cell Metab
, vol.1
, Issue.1
, pp. 63-72
-
-
Coppari, R.1
Ichinose, M.2
Lee, C.E.3
Pullen, A.E.4
Kenny, C.D.5
McGovern, R.A.6
Tang, V.7
Liu, S.M.8
Ludwig, T.9
Chua, Jr.S.C.10
Lowell, B.B.11
Elmquist, J.K.12
-
21
-
-
0030894113
-
The arcuate nucleus as a primary site of satiety effect of leptin in rats
-
9131658 10.1016/S0304-3940(97)00163-8 1:CAS:528:DyaK2sXisVelsLc%3D
-
Satoh N, Ogawa Y, Katsuura G, Hayase M, Tsuji T, Imagawa K, Yoshimasa Y, Nishi S, Hosoda K, Nakao K (1997) The arcuate nucleus as a primary site of satiety effect of leptin in rats. Neurosci Lett 224(3):149-152
-
(1997)
Neurosci Lett
, vol.224
, Issue.3
, pp. 149-152
-
-
Satoh, N.1
Ogawa, Y.2
Katsuura, G.3
Hayase, M.4
Tsuji, T.5
Imagawa, K.6
Yoshimasa, Y.7
Nishi, S.8
Hosoda, K.9
Nakao, K.10
-
22
-
-
0037733115
-
Arcuate nucleus-specific leptin receptor gene therapy attenuates the obesity phenotype of Koletsky (fa(k)/fa(k)) rats. e
-
12697710 10.1210/en.2002-0115 1:CAS:528:DC%2BD3sXjt1Witrw%3D
-
Morton GJ, Niswender KD, Rhodes CJ, Myers MG Jr, Blevins JE, Baskin DG, Schwartz MW (2003) Arcuate nucleus-specific leptin receptor gene therapy attenuates the obesity phenotype of Koletsky (fa(k)/fa(k)) rats. E. Endocrinology 144(5):2016-2024
-
(2003)
Endocrinology
, vol.144
, Issue.5
, pp. 2016-2024
-
-
Morton, G.J.1
Niswender, K.D.2
Rhodes, C.J.3
Myers, Jr.M.G.4
Blevins, J.E.5
Baskin, D.G.6
Schwartz, M.W.7
-
23
-
-
0030759490
-
Attenuation of leptin-mediated effects by monosodium glutamate-induced arcuate nucleus damage
-
Dawson R, Pelleymounter MA, Millard WJ, Liu S, Eppler B (1997) Attenuation of leptin-mediated effects by monosodium glutamate-induced arcuate nucleus damage. Am J Physiol 273(1Pt1):E202-6
-
(1997)
Am J Physiol
, vol.273
, Issue.1 PART 1
-
-
Dawson, R.1
Pelleymounter, M.A.2
Millard, W.J.3
Liu, S.4
Eppler, B.5
-
24
-
-
84863267488
-
Direct leptin action on POMC neurons regulates glucose homeostasis and hepatic insulin sensitivity in mice
-
22326958 10.1172/JCI59816 1:CAS:528:DC%2BC38XjsV2msbk%3D
-
Berglund ED, Vianna CR, Donato J Jr, Kim MH, Chuang JC, Lee CE, Lauzon DA, Lin P, Brule LJ, Scott MM, Coppari R, Elmquist JK (2012) Direct leptin action on POMC neurons regulates glucose homeostasis and hepatic insulin sensitivity in mice. J Clin Invest 122(3):1000-1009
-
(2012)
J Clin Invest
, vol.122
, Issue.3
, pp. 1000-1009
-
-
Berglund, E.D.1
Vianna, C.R.2
Donato, Jr.J.3
Kim, M.H.4
Chuang, J.C.5
Lee, C.E.6
Lauzon, D.A.7
Lin, P.8
Brule, L.J.9
Scott, M.M.10
Coppari, R.11
Elmquist, J.K.12
-
25
-
-
66049133685
-
Leptin-dependent control of glucose balance and locomotor activity by POMC neurons
-
19490908 10.1016/j.cmet.2009.05.003 1:CAS:528:DC%2BD1MXps1ensrg%3D
-
Huo L, Gamber K, Greeley S, Silva J, Huntoon N, Leng XH, Bjorbaek C (2009) Leptin-dependent control of glucose balance and locomotor activity by POMC neurons. Cell Metab 9(6):537-547
-
(2009)
Cell Metab
, vol.9
, Issue.6
, pp. 537-547
-
-
Huo, L.1
Gamber, K.2
Greeley, S.3
Silva, J.4
Huntoon, N.5
Leng, X.H.6
Bjorbaek, C.7
-
26
-
-
30044447631
-
Leptin regulates insulin sensitivity via phosphatidylinositol-3-OH kinase signaling in mediobasal hypothalamic neurons
-
16330326 10.1016/j.cmet.2005.10.009 1:CAS:528:DC%2BD2MXhtlequrnN
-
Morton GJ, Gelling RW, Niswender KD, Morrison CD, Rhodes CJ, Schwartz MW (2005) Leptin regulates insulin sensitivity via phosphatidylinositol-3-OH kinase signaling in mediobasal hypothalamic neurons. Cell Metab 2(6):411-420
-
(2005)
Cell Metab
, vol.2
, Issue.6
, pp. 411-420
-
-
Morton, G.J.1
Gelling, R.W.2
Niswender, K.D.3
Morrison, C.D.4
Rhodes, C.J.5
Schwartz, M.W.6
-
27
-
-
33847058514
-
Hypothalamic arcuate nucleus mediates the sympathetic and arterial pressure responses to leptin
-
17190874 10.1161/01.HYP.0000254827.59792.b2 1:CAS:528: DC%2BD2sXhslCmsLg%3D
-
Rahmouni K, Morgan DA (2007) Hypothalamic arcuate nucleus mediates the sympathetic and arterial pressure responses to leptin. Hypertension 49(3):647-652
-
(2007)
Hypertension
, vol.49
, Issue.3
, pp. 647-652
-
-
Rahmouni, K.1
Morgan, D.A.2
-
28
-
-
26044475601
-
Structural and functional evidence supporting a role for leptin in central neural pathways influencing blood pressure in rats
-
16105939 10.1113/expphysiol.2005.030775 1:CAS:528:DC%2BD2MXhtFKkt7%2FI
-
Montanaro MS, Allen AM, Oldfield BJ (2005) Structural and functional evidence supporting a role for leptin in central neural pathways influencing blood pressure in rats. Exp Physiol 90(5):689-696
-
(2005)
Exp Physiol
, vol.90
, Issue.5
, pp. 689-696
-
-
Montanaro, M.S.1
Allen, A.M.2
Oldfield, B.J.3
-
29
-
-
0031829004
-
Sympathetic activation to leptin is mediated by the hypothalamus
-
10.1097/00004872-199816080-00001
-
Haynes W, Morgan D, Walsh S (1998) Sympathetic activation to leptin is mediated by the hypothalamus. J Hypertens 16:S11
-
(1998)
J Hypertens
, vol.16
, pp. 11
-
-
Haynes, W.1
Morgan, D.2
Walsh, S.3
-
30
-
-
79954701326
-
Ablation of the Leptin Receptor in the Hypothalamic Arcuate Nucleus Abrogates Leptin-Induced Sympathetic Activation
-
21311043 10.1161/CIRCRESAHA.111.240226 1:CAS:528:DC%2BC3MXktFeks78%3D
-
Harlan SM, Morgan DA, Agassandian K, Guo DF, Cassell MD, Sigmund CD, Mark AL, Rahmouni K (2011) Ablation of the Leptin Receptor in the Hypothalamic Arcuate Nucleus Abrogates Leptin-Induced Sympathetic Activation. Circ Res 108(7):808-812
-
(2011)
Circ Res
, vol.108
, Issue.7
, pp. 808-812
-
-
Harlan, S.M.1
Morgan, D.A.2
Agassandian, K.3
Guo, D.F.4
Cassell, M.D.5
Sigmund, C.D.6
Mark, A.L.7
Rahmouni, K.8
-
31
-
-
0033200153
-
Integration of NPY, AGRP, and melanocortin signals in the hypothalamic paraventricular nucleus: Evidence of a cellular basis for the adipostat
-
10677034 10.1016/S0896-6273(00)80829-6 1:CAS:528:DyaK1MXmsVOrsrc%3D
-
Cowley MA, Pronchuk N, Fan W, Dinulescu DM, Colmers WF, Cone RD (1999) Integration of NPY, AGRP, and melanocortin signals in the hypothalamic paraventricular nucleus: evidence of a cellular basis for the adipostat. Neuron 24(1):155-163
-
(1999)
Neuron
, vol.24
, Issue.1
, pp. 155-163
-
-
Cowley, M.A.1
Pronchuk, N.2
Fan, W.3
Dinulescu, D.M.4
Colmers, W.F.5
Cone, R.D.6
-
32
-
-
0027436690
-
Identification of a receptor for gamma melanotropin and other proopiomelanocortin peptides in the hypothalamus and limbic system
-
8415620 10.1073/pnas.90.19.8856 1:STN:280:DyaK2c%2Fit1aksQ%3D%3D
-
Roselli-Rehfuss L, Mountjoy KG, Robbins LS, Mortrud MT, Low MJ, Tatro JB, Entwistle ML, Simerly RB, Cone RD (1993) Identification of a receptor for gamma melanotropin and other proopiomelanocortin peptides in the hypothalamus and limbic system. Proc Natl Acad Sci U S A 90(19):8856-8860
-
(1993)
Proc Natl Acad Sci U S A
, vol.90
, Issue.19
, pp. 8856-8860
-
-
Roselli-Rehfuss, L.1
Mountjoy, K.G.2
Robbins, L.S.3
Mortrud, M.T.4
Low, M.J.5
Tatro, J.B.6
Entwistle, M.L.7
Simerly, R.B.8
Cone, R.D.9
-
33
-
-
23244451186
-
Melanocortin-4 receptor-deficient mice are not hypertensive or salt-sensitive despite obesity, hyperinsulinemia, and hyperleptinemia
-
16027245 10.1161/01.HYP.0000175474.99326.bf 1:CAS:528: DC%2BD2MXmtlSisrY%3D
-
Tallam LS, Stec DE, Willis MA, da Silva AA, Hall JE (2005) Melanocortin-4 receptor-deficient mice are not hypertensive or salt-sensitive despite obesity, hyperinsulinemia, and hyperleptinemia. Hypertension 46(2):326-332
-
(2005)
Hypertension
, vol.46
, Issue.2
, pp. 326-332
-
-
Tallam, L.S.1
Stec, D.E.2
Willis, M.A.3
Da Silva, A.A.4
Hall, J.E.5
-
34
-
-
0038149085
-
Role of melanocortin-4 receptors in mediating renal sympathoactivation to leptin and insulin
-
12853417 1:CAS:528:DC%2BD3sXls1Wqs7k%3D
-
Rahmouni K, Haynes WG, Morgan DA, Mark AL (2003) Role of melanocortin-4 receptors in mediating renal sympathoactivation to leptin and insulin. J Neurosci 23(14):5998-6004
-
(2003)
J Neurosci
, vol.23
, Issue.14
, pp. 5998-6004
-
-
Rahmouni, K.1
Haynes, W.G.2
Morgan, D.A.3
Mark, A.L.4
-
35
-
-
0842311502
-
Role of adrenergic activity in pressor responses to chronic melanocortin receptor activation
-
Kuo JJ, da Silva AA, Tallam LS, Hall JE (2004) Role of adrenergic activity in pressor responses to chronic melanocortin receptor activation. Hypertension 43(2):370-375
-
(2004)
Hypertension
, vol.43
, Issue.2
, pp. 370-375
-
-
Kuo, J.J.1
Da Silva, A.A.2
Tallam, L.S.3
Hall, J.E.4
-
36
-
-
0037338712
-
Hypothalamic melanocortin receptors and chronic regulation of arterial pressure and renal function
-
Kuo JJ, Silva AA, Hall JE (2003) Hypothalamic melanocortin receptors and chronic regulation of arterial pressure and renal function. Hypertension 41(3Pt2):768-774
-
(2003)
Hypertension
, vol.41
, Issue.3 PART 2
, pp. 768-774
-
-
Kuo, J.J.1
Silva, A.A.2
Hall, J.E.3
-
37
-
-
77951648854
-
Sympathetic function in human carriers of melanocortin-4 receptor gene mutations
-
20147580 10.1210/jc.2009-2297 1:CAS:528:DC%2BC3cXltFSntr8%3D
-
Sayk F, Heutling D, Dodt C, Iwen KA, Wellhoner JP, Scherag S, Hinney A, Hebebrand J, Lehnert H (2010) Sympathetic function in human carriers of melanocortin-4 receptor gene mutations. J Clin Endocrinol Metab 95(4):1998-2002
-
(2010)
J Clin Endocrinol Metab
, vol.95
, Issue.4
, pp. 1998-2002
-
-
Sayk, F.1
Heutling, D.2
Dodt, C.3
Iwen, K.A.4
Wellhoner, J.P.5
Scherag, S.6
Hinney, A.7
Hebebrand, J.8
Lehnert, H.9
-
38
-
-
58249087146
-
Modulation of blood pressure by central melanocortinergic pathways
-
19092146 10.1056/NEJMoa0803085 1:CAS:528:DC%2BD1MXhvFOrug%3D%3D
-
Greenfield JR, Miller JW, Keogh JM, Henning E, Satterwhite JH, Cameron GS, Astruc B, Mayer JP, Brage S, See TC, Lomas DJ, O'Rahilly S, Farooqi IS (2009) Modulation of blood pressure by central melanocortinergic pathways. N Engl J Med 360(1):44-52
-
(2009)
N Engl J Med
, vol.360
, Issue.1
, pp. 44-52
-
-
Greenfield, J.R.1
Miller, J.W.2
Keogh, J.M.3
Henning, E.4
Satterwhite, J.H.5
Cameron, G.S.6
Astruc, B.7
Mayer, J.P.8
Brage, S.9
See, T.C.10
Lomas, D.J.11
O'Rahilly, S.12
Farooqi, I.S.13
-
39
-
-
79955471654
-
Control of blood pressure, appetite, and glucose by leptin in mice lacking leptin receptors in proopiomelanocortin neurons
-
do Carmo JM, da Silva AA, Cai Z, Lin S, Dubinion JH, Hall JE (2011) Control of blood pressure, appetite, and glucose by leptin in mice lacking leptin receptors in proopiomelanocortin neurons. Hypertension 57(5):918-926
-
(2011)
Hypertension
, vol.57
, Issue.5
, pp. 918-926
-
-
Do Carmo, J.M.1
Da Silva, A.A.2
Cai, Z.3
Lin, S.4
Dubinion, J.H.5
Hall, J.E.6
-
40
-
-
57749112002
-
Mechanisms mediating renal sympathetic activation to leptin in obesity
-
18815209 10.1152/ajpregu.90324.2008 1:CAS:528:DC%2BD1cXhsFSntbjF
-
Morgan DA, Thedens DR, Weiss R, Rahmouni K (2008) Mechanisms mediating renal sympathetic activation to leptin in obesity. Am J Physiol Regul Integr Comp Physiol 295(6):R1730-R1736
-
(2008)
Am J Physiol Regul Integr Comp Physiol
, vol.295
, Issue.6
-
-
Morgan, D.A.1
Thedens, D.R.2
Weiss, R.3
Rahmouni, K.4
-
41
-
-
0942298220
-
Melanocortin receptors mediate the excitatory effects of blood-borne murine leptin on hypothalamic paraventricular neurons in rat
-
14707012 10.1152/ajpregu.00504.2003 1:CAS:528:DC%2BD2cXhsFKru78%3D
-
Zhang ZH, Felder RB (2004) Melanocortin receptors mediate the excitatory effects of blood-borne murine leptin on hypothalamic paraventricular neurons in rat. Am J Physiol Regul Integr Comp Physiol 286(2):R303-R310
-
(2004)
Am J Physiol Regul Integr Comp Physiol
, vol.286
, Issue.2
-
-
Zhang, Z.H.1
Felder, R.B.2
-
42
-
-
0035313069
-
Leptin-induced nuclear translocation of STAT3 immunoreactivity in hypothalamic nuclei involved in body weight regulation
-
11264315 1:CAS:528:DC%2BD3MXjslCls78%3D
-
Hubschle T, Thom E, Watson A, Roth J, Klaus S, Meyerhof W (2001) Leptin-induced nuclear translocation of STAT3 immunoreactivity in hypothalamic nuclei involved in body weight regulation. J Neurosci 21(7):2413-2424
-
(2001)
J Neurosci
, vol.21
, Issue.7
, pp. 2413-2424
-
-
Hubschle, T.1
Thom, E.2
Watson, A.3
Roth, J.4
Klaus, S.5
Meyerhof, W.6
-
43
-
-
0031054014
-
Leptin activates neurons in ventrobasal hypothalamus and brainstem
-
9003024 10.1210/en.138.2.839 1:CAS:528:DyaK2sXntVGqtQ%3D%3D
-
Elmquist JK, Ahima RS, Maratos-Flier E, Flier JS, Saper CB (1997) Leptin activates neurons in ventrobasal hypothalamus and brainstem. Endocrinology 138(2):839-842
-
(1997)
Endocrinology
, vol.138
, Issue.2
, pp. 839-842
-
-
Elmquist, J.K.1
Ahima, R.S.2
Maratos-Flier, E.3
Flier, J.S.4
Saper, C.B.5
-
44
-
-
42449086900
-
Selective loss of leptin receptors in the ventromedial hypothalamic nucleus results in increased adiposity and a metabolic syndrome
-
18258679 10.1210/en.2007-1200 1:CAS:528:DC%2BD1cXht1GmsLvF
-
Bingham NC, Anderson KK, Reuter AL, Stallings NR, Parker KL (2008) Selective loss of leptin receptors in the ventromedial hypothalamic nucleus results in increased adiposity and a metabolic syndrome. Endocrinology 149(5):2138-2148
-
(2008)
Endocrinology
, vol.149
, Issue.5
, pp. 2138-2148
-
-
Bingham, N.C.1
Anderson, K.K.2
Reuter, A.L.3
Stallings, N.R.4
Parker, K.L.5
-
45
-
-
30644473109
-
Leptin directly activates SF1 neurons in the VMH, and this action by leptin is required for normal body-weight homeostasis
-
16423694 10.1016/j.neuron.2005.12.021 1:CAS:528:DC%2BD28Xht1SrtbY%3D
-
Dhillon H, Zigman JM, Ye C, Lee CE, McGovern RA, Tang V, Kenny CD, Christiansen LM, White RD, Edelstein EA, Coppari R, Balthasar N, Cowley MA, Chua S Jr, Elmquist JK, Lowell BB (2006) Leptin directly activates SF1 neurons in the VMH, and this action by leptin is required for normal body-weight homeostasis. Neuron 49(2):191-203
-
(2006)
Neuron
, vol.49
, Issue.2
, pp. 191-203
-
-
Dhillon, H.1
Zigman, J.M.2
Ye, C.3
Lee, C.E.4
McGovern, R.A.5
Tang, V.6
Kenny, C.D.7
Christiansen, L.M.8
White, R.D.9
Edelstein, E.A.10
Coppari, R.11
Balthasar, N.12
Cowley, M.A.13
Chua, Jr.S.14
Elmquist, J.K.15
Lowell, B.B.16
-
46
-
-
0032833029
-
Sympathetic activation of leptin via the ventromedial hypothalamus: Leptin-induced increase in catecholamine secretion
-
10480609 10.2337/diabetes.48.9.1787 1:CAS:528:DyaK1MXmtVaitLg%3D
-
Satoh N, Ogawa Y, Katsuura G, Numata Y, Tsuji T, Hayase M, Ebihara K, Masuzaki H, Hosoda K, Yoshimasa Y, Nakao K (1999) Sympathetic activation of leptin via the ventromedial hypothalamus: leptin-induced increase in catecholamine secretion. Diabetes 48(9):1787-1793
-
(1999)
Diabetes
, vol.48
, Issue.9
, pp. 1787-1793
-
-
Satoh, N.1
Ogawa, Y.2
Katsuura, G.3
Numata, Y.4
Tsuji, T.5
Hayase, M.6
Ebihara, K.7
Masuzaki, H.8
Hosoda, K.9
Yoshimasa, Y.10
Nakao, K.11
-
47
-
-
0141997258
-
Cardiovascular responses evoked by leptin acting on neurons in the ventromedial and dorsomedial hypothalamus
-
12939234 10.1161/01.HYP.0000090097.22678.0A 1:CAS:528: DC%2BD3sXnsFamsb0%3D
-
Marsh AJ, Fontes MA, Killinger S, Pawlak DB, Polson JW, Dampney RA (2003) Cardiovascular responses evoked by leptin acting on neurons in the ventromedial and dorsomedial hypothalamus. Hypertension 42(4):488-493
-
(2003)
Hypertension
, vol.42
, Issue.4
, pp. 488-493
-
-
Marsh, A.J.1
Fontes, M.A.2
Killinger, S.3
Pawlak, D.B.4
Polson, J.W.5
Dampney, R.A.6
-
48
-
-
0041621613
-
Activation of the renal sympathetic nerve by leptin microinjection into the ventromedial hypothalamus in rats
-
12929569 1:CAS:528:DC%2BD3sXmvFSrsrY%3D
-
Tanida M, Nagai K, Kaneko H (2003) Activation of the renal sympathetic nerve by leptin microinjection into the ventromedial hypothalamus in rats. In Vivo 17(3):213-217
-
(2003)
Vivo
, vol.17
, Issue.3
, pp. 213-217
-
-
Tanida, M.1
Nagai, K.2
Kaneko, H.3
-
49
-
-
0034979717
-
Descending pathways mediating cardiovascular response from dorsomedial hypothalamic nucleus
-
11356650 1:CAS:528:DC%2BD3MXksFCltrc%3D
-
Fontes MA, Tagawa T, Polson JW, Cavanagh SJ, Dampney RA (2001) Descending pathways mediating cardiovascular response from dorsomedial hypothalamic nucleus. Am J Physiol Heart Circ Physiol 280(6):H2891-H2901
-
(2001)
Am J Physiol Heart Circ Physiol
, vol.280
, Issue.6
-
-
Fontes, M.A.1
Tagawa, T.2
Polson, J.W.3
Cavanagh, S.J.4
Dampney, R.A.5
-
50
-
-
79551512119
-
Leptin-receptor-expressing neurons in the dorsomedial hypothalamus and median preoptic area regulate sympathetic brown adipose tissue circuits
-
21289197 10.1523/JNEUROSCI.3223-10.2011 1:CAS:528:DC%2BC3MXhvFGrsrs%3D
-
Zhang Y, Kerman IA, Laque A, Nguyen P, Faouzi M, Louis GW, Jones JC, Rhodes C, Munzberg H (2011) Leptin-receptor-expressing neurons in the dorsomedial hypothalamus and median preoptic area regulate sympathetic brown adipose tissue circuits. J Neurosci 31(5):1873-1884
-
(2011)
J Neurosci
, vol.31
, Issue.5
, pp. 1873-1884
-
-
Zhang, Y.1
Kerman, I.A.2
Laque, A.3
Nguyen, P.4
Faouzi, M.5
Louis, G.W.6
Jones, J.C.7
Rhodes, C.8
Munzberg, H.9
-
51
-
-
80052156758
-
Leptin action in the dorsomedial hypothalamus increases sympathetic tone to brown adipose tissue in spite of systemic leptin resistance
-
21865462 10.1523/JNEUROSCI.2336-11.2011 1:CAS:528:DC%2BC3MXhtFCisLnN
-
Enriori PJ, Sinnayah P, Simonds SE, Garcia RC, Cowley MA (2011) Leptin action in the dorsomedial hypothalamus increases sympathetic tone to brown adipose tissue in spite of systemic leptin resistance. J Neurosci 31(34):12189-12197
-
(2011)
J Neurosci
, vol.31
, Issue.34
, pp. 12189-12197
-
-
Enriori, P.J.1
Sinnayah, P.2
Simonds, S.E.3
Garcia, R.C.4
Cowley, M.A.5
-
52
-
-
79960425949
-
Lateral thinking about leptin: A review of leptin action via the lateral hypothalamus
-
21550356 10.1016/j.physbeh.2011.04.060 1:CAS:528:DC%2BC3MXptVSqtb8%3D
-
Leinninger GM (2011) Lateral thinking about leptin: a review of leptin action via the lateral hypothalamus. Physiol Behav 104(4):572-581
-
(2011)
Physiol Behav
, vol.104
, Issue.4
, pp. 572-581
-
-
Leinninger, G.M.1
-
53
-
-
80052707655
-
Leptin action via neurotensin neurons controls orexin, the mesolimbic dopamine system and energy balance
-
21907138 10.1016/j.cmet.2011.06.016 1:CAS:528:DC%2BC3MXhtFGltbnK
-
Leinninger GM, Opland DM, Jo YH, Faouzi M, Christensen L, Cappellucci LA, Rhodes CJ, Gnegy ME, Becker JB, Pothos EN, Seasholtz AF, Thompson RC, Myers MG Jr (2011) Leptin action via neurotensin neurons controls orexin, the mesolimbic dopamine system and energy balance. Cell Metab 14(3):313-323
-
(2011)
Cell Metab
, vol.14
, Issue.3
, pp. 313-323
-
-
Leinninger, G.M.1
Opland, D.M.2
Jo, Y.H.3
Faouzi, M.4
Christensen, L.5
Cappellucci, L.A.6
Rhodes, C.J.7
Gnegy, M.E.8
Becker, J.B.9
Pothos, E.N.10
Seasholtz, A.F.11
Thompson, R.C.12
Myers, Jr.M.G.13
-
54
-
-
0038307360
-
Differential role of leptin receptors at the hypothalamic paraventricular nucleus in tonic regulation of food intake and cardiovascular functions
-
12824696 10.1007/BF02256428 1:CAS:528:DC%2BD3sXkvVegsrc%3D
-
Shih CD, Au LC, Chan JY (2003) Differential role of leptin receptors at the hypothalamic paraventricular nucleus in tonic regulation of food intake and cardiovascular functions. J Biomed Sci 10(4):367-378
-
(2003)
J Biomed Sci
, vol.10
, Issue.4
, pp. 367-378
-
-
Shih, C.D.1
Au, L.C.2
Chan, J.Y.3
-
55
-
-
59849116907
-
Leptin signaling in the nucleus tractus solitarii increases sympathetic nerve activity to the kidney
-
19103999 10.1161/HYPERTENSIONAHA.108.124255 1:CAS:528: DC%2BD1MXlvFSqtQ%3D%3D
-
Mark AL, Agassandian K, Morgan DA, Liu X, Cassell MD, Rahmouni K (2009) Leptin signaling in the nucleus tractus solitarii increases sympathetic nerve activity to the kidney. Hypertension 53(2):375-380
-
(2009)
Hypertension
, vol.53
, Issue.2
, pp. 375-380
-
-
Mark, A.L.1
Agassandian, K.2
Morgan, D.A.3
Liu, X.4
Cassell, M.D.5
Rahmouni, K.6
-
56
-
-
0036142589
-
Evidence that the caudal brainstem is a target for the inhibitory effect of leptin on food intake
-
11751615 10.1210/en.143.1.239 1:CAS:528:DC%2BD38XjtVyjsw%3D%3D
-
Grill HJ, Schwartz MW, Kaplan JM, Foxhall JS, Breininger J, Baskin DG (2002) Evidence that the caudal brainstem is a target for the inhibitory effect of leptin on food intake. Endocrinology 143(1):239-246
-
(2002)
Endocrinology
, vol.143
, Issue.1
, pp. 239-246
-
-
Grill, H.J.1
Schwartz, M.W.2
Kaplan, J.M.3
Foxhall, J.S.4
Breininger, J.5
Baskin, D.G.6
-
57
-
-
33745142241
-
Characterization of leptin-responsive neurons in the caudal brainstem
-
16601142 10.1210/en.2005-0877 1:CAS:528:DC%2BD28XmtlOku7g%3D
-
Ellacott KL, Halatchev IG, Cone RD (2006) Characterization of leptin-responsive neurons in the caudal brainstem. Endocrinology 147(7):3190-3195
-
(2006)
Endocrinology
, vol.147
, Issue.7
, pp. 3190-3195
-
-
Ellacott, K.L.1
Halatchev, I.G.2
Cone, R.D.3
-
58
-
-
33644768285
-
Divergent regulation of proopiomelanocortin neurons by leptin in the nucleus of the solitary tract and in the arcuate hypothalamic nucleus
-
16505217 10.2337/diabetes.55.03.06.db05-1143 1:CAS:528: DC%2BD28XisVWisr4%3D
-
Huo L, Grill HJ, Bjorbaek C (2006) Divergent regulation of proopiomelanocortin neurons by leptin in the nucleus of the solitary tract and in the arcuate hypothalamic nucleus. Diabetes 55(3):567-573
-
(2006)
Diabetes
, vol.55
, Issue.3
, pp. 567-573
-
-
Huo, L.1
Grill, H.J.2
Bjorbaek, C.3
-
59
-
-
84863418840
-
Cardiovascular actions of leptin in the subfornical organ are abolished by diet induced obesity
-
10.1111/j.1365-2826.2011.02257.x
-
Smith PM, Ferguson AV (2011) Cardiovascular actions of leptin in the subfornical organ are abolished by diet induced obesity. J Neuroendocrinol 24(3):504-510
-
(2011)
J Neuroendocrinol
, vol.24
, Issue.3
, pp. 504-510
-
-
Smith, P.M.1
Ferguson, A.V.2
-
60
-
-
0037008480
-
Biomedicine. A sympathetic defense against obesity
-
12161638 10.1126/science.1074923
-
Dulloo AG (2002) Biomedicine. A sympathetic defense against obesity. Science 297(5582):780-781
-
(2002)
Science
, vol.297
, Issue.5582
, pp. 780-781
-
-
Dulloo, A.G.1
|