Exposure to a high-fat diet alters leptin sensitivity and elevates renal sympathetic nerve activity and arterial pressure in rabbits

Hypertension

Volumn 55, Issue 4, 2010, Pages 862-868

  Prior, Larissa J ^a,b   Eikelis, Nina ^a   Armitage, James A ^a,c   Davern, Pamela J ^a   Burke, Sandra L ^a   Montani, Jean Pierre ^d   Barzel, Benjamin ^a,c   Head, Geoffrey A ^a  

^a BAKER IDI HEART AND DIABETES INSTITUTE   (Australia)

^b UNIVERSITY OF MELBOURNE   (Australia)

^c MONASH UNIVERSITY   (Australia)

^d UNIVERSITY OF FRIBOURG   (Switzerland)

Author keywords

Hypothalamus; Leptin; Leptin resistance; New Zealand white rabbit; Obesity related hypertension; Sympathetic nervous system

Indexed keywords

LEPTIN; NORADRENALIN; PROTEIN C FOS; LEPTIN RECEPTOR;

ADRENERGIC ACTIVITY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD PRESSURE FLUCTUATION; BODY FAT DISTRIBUTION; CARDIOVASCULAR EFFECT; CONTROLLED STUDY; HEART RATE; KIDNEY FUNCTION; KIDNEY NERVE; LIPID DIET; MALE; MEAN ARTERIAL PRESSURE; NONHUMAN; NORADRENALIN BLOOD LEVEL; OBESITY; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; RABBIT; WEIGHT GAIN; WHITE ADIPOSE TISSUE; ADRENERGIC SYSTEM; ANALYSIS OF VARIANCE; ANIMAL; BLOOD PRESSURE; BODY WEIGHT; DOSE RESPONSE; DRUG EFFECT; FAT INTAKE; HYPOTHALAMUS; INDWELLING CATHETER; INNERVATION; INTRAABDOMINAL FAT; INTRACEREBROVENTRICULAR DRUG ADMINISTRATION; KIDNEY; METABOLISM; NERVE CELL; PHYSIOLOGY;

ANALYSIS OF VARIANCE; ANIMALS; BLOOD PRESSURE; BODY WEIGHT; CATHETERS, INDWELLING; DIETARY FATS; DOSE-RESPONSE RELATIONSHIP, DRUG; HEART RATE; HYPOTHALAMUS; INJECTIONS, INTRAVENTRICULAR; INTRA-ABDOMINAL FAT; KIDNEY; LEPTIN; MALE; NEURONS; PROTO-ONCOGENE PROTEINS C-FOS; RABBITS; RECEPTORS, LEPTIN; SYMPATHETIC NERVOUS SYSTEM;

EID: 77950507182     PISSN: 0194911X     EISSN: None     Source Type: Journal    
DOI: 10.1161/HYPERTENSIONAHA.109.141119     Document Type: Article

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