Ablation of the leptin receptor in the hypothalamic arcuate nucleus abrogates leptin-induced sympathetic activation

Circulation Research

Volumn 108, Issue 7, 2011, Pages 808-812

  Harlan, Shannon M ^a   Morgan, Donald A ^a   Agassandian, Khristofor ^a   Guo, Deng Fu ^a   Cassell, Martin D ^a   Sigmund, Curt D ^a   Mark, Allyn L ^a   Rahmouni, Kamal ^a  

^a UNIVERSITY OF IOWA   (United States)

Author keywords

arcuate nucleus; hypertension; leptin; obesity; sympathetic tone

Indexed keywords

CRE RECOMBINASE; LEPTIN RECEPTOR; STAT3 PROTEIN;

ADIPOSE TISSUE; ADRENERGIC SYSTEM; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARCUATE NUCLEUS; ARTERIAL PRESSURE; ARTICLE; CONTROLLED STUDY; HYPOTHALAMUS NUCLEUS; KIDNEY NERVE; MOUSE; NONHUMAN; OBESITY; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; SYMPATHETIC TONE;

ADENOVIRIDAE; ANIMALS; ARCUATE NUCLEUS; DISEASE MODELS, ANIMAL; GENE DELETION; GREEN FLUORESCENT PROTEINS; HOMOZYGOTE; INTEGRASES; LEPTIN; MICE; MICE, INBRED C57BL; OBESITY; RECEPTORS, LEPTIN; SYMPATHETIC NERVOUS SYSTEM;

EID: 79954701326     PISSN: 00097330     EISSN: 15244571     Source Type: Journal    
DOI: 10.1161/CIRCRESAHA.111.240226     Document Type: Article

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