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Volumn 286, Issue 2 55-2, 2004, Pages

Melanocortin receptors mediate the excitatory effects of blood-borne murine leptin on hypothalamic paraventricular neurons in rat

Author keywords

Extracellular recording; Neuropeptide Y; Obesity; Sympathetic nerve activity; melanocyte stimulating hormone

Indexed keywords

LEPTIN; MELANOCORTIN 3 RECEPTOR; MELANOCORTIN 4 RECEPTOR; MELANOCORTIN RECEPTOR; N ACETYL ALPHA INTERMEDIN[4-10]CYCLO[4 NORLEUCINE 5 ASPARTIC ACID 7 [3 (2 NAPHTHYL)ALANINE] 10 LYSINAMIDE]; NEUROPEPTIDE Y; RECEPTOR SUBTYPE; URETHAN;

EID: 0942298220     PISSN: 03636119     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpregu.00504.2003     Document Type: Article
Times cited : (32)

References (37)
  • 1
    • 0001475715 scopus 로고    scopus 로고
    • Guiding principles for research involving animals and human beings
    • American Physiological Society. Guiding principles for research involving animals and human beings. Am J Physiol Regul Integr Comp Physiol 283: R281-R283, 2002.
    • (2002) Am J Physiol Regul Integr Comp Physiol , vol.283
  • 3
    • 0032443807 scopus 로고    scopus 로고
    • The neuropeptide Y/agouti gene-related protein (AGRP) brain circuitry in normal, anorectic, and monosodium glutamate-treated mice
    • Broberger C, Johansen J, Johansson C, Schalling M, and Hokfelt T. The neuropeptide Y/agouti gene-related protein (AGRP) brain circuitry in normal, anorectic, and monosodium glutamate-treated mice. Proc Natl Acad Sci USA 95: 15043-15048, 1998.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 15043-15048
    • Broberger, C.1    Johansen, J.2    Johansson, C.3    Schalling, M.4    Hokfelt, T.5
  • 4
    • 0036179086 scopus 로고    scopus 로고
    • Chronic cardiovascular and renal actions of leptin: Role of adrenergic activity
    • Carlyle M, Jones OB, Kuo JJ, and Hall JE. Chronic cardiovascular and renal actions of leptin: role of adrenergic activity. Hypertension 39: 496-501, 2002.
    • (2002) Hypertension , vol.39 , pp. 496-501
    • Carlyle, M.1    Jones, O.B.2    Kuo, J.J.3    Hall, J.E.4
  • 5
    • 0035100787 scopus 로고    scopus 로고
    • Leptin acts in the central nervous system to produce dose-dependent changes in arterial pressure
    • Correia ML, Morgan DA, Sivitz WI, Mark AL, and Haynes WG. Leptin acts in the central nervous system to produce dose-dependent changes in arterial pressure. Hypertension 37: 936-942, 2001.
    • (2001) Hypertension , vol.37 , pp. 936-942
    • Correia, M.L.1    Morgan, D.A.2    Sivitz, W.I.3    Mark, A.L.4    Haynes, W.G.5
  • 6
    • 0033200153 scopus 로고    scopus 로고
    • Integration of NPY, AGRP, and melanocortin signals in the hypothalamic paraventricular nucleus: Evidence of a cellular basis for the adipostat
    • Cowley MA, Pronchuk N, Fan W, Dinulescu DM, Colmers WF, and Cone RD. Integration of NPY, AGRP, and melanocortin signals in the hypothalamic paraventricular nucleus: evidence of a cellular basis for the adipostat. Neuron 24: 155-163, 1999.
    • (1999) Neuron , vol.24 , pp. 155-163
    • Cowley, M.A.1    Pronchuk, N.2    Fan, W.3    Dinulescu, D.M.4    Colmers, W.F.5    Cone, R.D.6
  • 8
    • 0037341979 scopus 로고    scopus 로고
    • Central angiotensin modulation of baroreflex control of renal sympathetic nerve activity in the rat: Influence of dietary sodium
    • DiBona GF. Central angiotensin modulation of baroreflex control of renal sympathetic nerve activity in the rat: influence of dietary sodium. Acta Physiol Scand 177: 285-289, 2003.
    • (2003) Acta Physiol Scand , vol.177 , pp. 285-289
    • DiBona, G.F.1
  • 9
    • 0026061245 scopus 로고
    • Neuropeptide Y suppresses sympathetic activity to interscapular brown adipose tissue in rats
    • Egawa M, Yoshimatsu H, and Bray GA. Neuropeptide Y suppresses sympathetic activity to interscapular brown adipose tissue in rats. Am J Physiol Regul Integr Comp Physiol 260: R328-R334, 1991.
    • (1991) Am J Physiol Regul Integr Comp Physiol , vol.260
    • Egawa, M.1    Yoshimatsu, H.2    Bray, G.A.3
  • 11
    • 0035851907 scopus 로고    scopus 로고
    • Hypothalamic pathways underlying the endocrine, autonomic, and behavioral effects of leptin
    • Elmquist JK. Hypothalamic pathways underlying the endocrine, autonomic, and behavioral effects of leptin. Physiol Behav 74: 703-708, 2001.
    • (2001) Physiol Behav , vol.74 , pp. 703-708
    • Elmquist, J.K.1
  • 14
    • 0032177037 scopus 로고    scopus 로고
    • Unraveling the central nervous system pathways underlying responses to leptin
    • Elmquist JK, Maratos-Flier E, Saper CB, and Flier JS. Unraveling the central nervous system pathways underlying responses to leptin. Nat Neurosci 1: 445-450, 1998.
    • (1998) Nat Neurosci , vol.1 , pp. 445-450
    • Elmquist, J.K.1    Maratos-Flier, E.2    Saper, C.B.3    Flier, J.S.4
  • 15
    • 0029946644 scopus 로고    scopus 로고
    • Sensitivity to leptin and susceptibility to seizures of mice lacking neuropeptide Y
    • Erickson JC, Clegg KE, and Palmiter RD. Sensitivity to leptin and susceptibility to seizures of mice lacking neuropeptide Y. Nature 381: 415-421, 1996.
    • (1996) Nature , vol.381 , pp. 415-421
    • Erickson, J.C.1    Clegg, K.E.2    Palmiter, R.D.3
  • 16
    • 0030614331 scopus 로고    scopus 로고
    • Role of melanocortinergic neurons in feeding and the agouti obesity syndrome
    • Fan W, Boston BA, Kesterson RA, Hruby VJ, and Cone RD. Role of melanocortinergic neurons in feeding and the agouti obesity syndrome. Nature 385: 165-168, 1997.
    • (1997) Nature , vol.385 , pp. 165-168
    • Fan, W.1    Boston, B.A.2    Kesterson, R.A.3    Hruby, V.J.4    Cone, R.D.5
  • 17
    • 0023873209 scopus 로고
    • Cardiovascular actions of neuropeptide Y in the hypothalamic paraventricular nucleus of conscious Long Evans and Brattleboro rats
    • Harland D, Bennett T, and Gardiner SM. Cardiovascular actions of neuropeptide Y in the hypothalamic paraventricular nucleus of conscious Long Evans and Brattleboro rats. Neurosci Lett 85: 239-243, 1988.
    • (1988) Neurosci Lett , vol.85 , pp. 239-243
    • Harland, D.1    Bennett, T.2    Gardiner, S.M.3
  • 18
    • 0032899719 scopus 로고    scopus 로고
    • Interactions between the melanocortin system and leptin in control of sympathetic nerve traffic
    • Haynes WG, Morgan DA, Djalali A, Sivitz WI, and Mark AL. Interactions between the melanocortin system and leptin in control of sympathetic nerve traffic. Hypertension 33: 542-547, 1999.
    • (1999) Hypertension , vol.33 , pp. 542-547
    • Haynes, W.G.1    Morgan, D.A.2    Djalali, A.3    Sivitz, W.I.4    Mark, A.L.5
  • 21
    • 0033664890 scopus 로고    scopus 로고
    • Central cardiovascular action of neuropeptide Y in conscious rabbits
    • Matsumura K, Tsuchihashi T, and Abe I. Central cardiovascular action of neuropeptide Y in conscious rabbits. Hypertension 36: 1040-1044, 2000.
    • (2000) Hypertension , vol.36 , pp. 1040-1044
    • Matsumura, K.1    Tsuchihashi, T.2    Abe, I.3
  • 22
    • 0037032105 scopus 로고    scopus 로고
    • Central α-melanocyte-stimulating hormone acts at melanocortin-4 receptor to activate sympathetic nervous system in conscious rabbits
    • Matsumura K, Tsuchihashi T, Abe I, and Iida M. Central α-melanocyte-stimulating hormone acts at melanocortin-4 receptor to activate sympathetic nervous system in conscious rabbits. Brain Res 948: 145-148, 2002.
    • (2002) Brain Res , vol.948 , pp. 145-148
    • Matsumura, K.1    Tsuchihashi, T.2    Abe, I.3    Iida, M.4
  • 23
    • 0035171118 scopus 로고    scopus 로고
    • Differential regulation of brown adipose and splanchnic sympathetic outflows in rat: Roles of raphe and rostral ventrolateral medulla neurons
    • Morrison SF. Differential regulation of brown adipose and splanchnic sympathetic outflows in rat: roles of raphe and rostral ventrolateral medulla neurons. Clin Exp Pharmacol Physiol 28: 138-143, 2001.
    • (2001) Clin Exp Pharmacol Physiol , vol.28 , pp. 138-143
    • Morrison, S.F.1
  • 24
    • 0034937620 scopus 로고    scopus 로고
    • Differential regulation of sympathetic outflows to vasoconstrictor and thermoregulatory effectors
    • Morrison SF. Differential regulation of sympathetic outflows to vasoconstrictor and thermoregulatory effectors. Ann NY Acad Sci 940: 286-298, 2001.
    • (2001) Ann NY Acad Sci , vol.940 , pp. 286-298
    • Morrison, S.F.1
  • 25
    • 0028134706 scopus 로고
    • Localization of the melanocortin-4 receptor (MC4-R) in neuroendocrine and autonomic control circuits in the brain
    • Mountjoy KG, Mortrud MT, Low MJ, Simerly RB, and Cone RD. Localization of the melanocortin-4 receptor (MC4-R) in neuroendocrine and autonomic control circuits in the brain. Mol Endocrinol 8: 1298-1308, 1994.
    • (1994) Mol Endocrinol , vol.8 , pp. 1298-1308
    • Mountjoy, K.G.1    Mortrud, M.T.2    Low, M.J.3    Simerly, R.B.4    Cone, R.D.5
  • 27
    • 0036773262 scopus 로고    scopus 로고
    • Leptin and neuropeptide Y have opposing modulatory effects on nucleus of the solitary tract neurophysiological responses to gastric loads: Implications for the control of food intake
    • Schwartz GJ and Moran TH. Leptin and neuropeptide Y have opposing modulatory effects on nucleus of the solitary tract neurophysiological responses to gastric loads: implications for the control of food intake. Endocrinology 143: 3779-3784, 2002.
    • (2002) Endocrinology , vol.143 , pp. 3779-3784
    • Schwartz, G.J.1    Moran, T.H.2
  • 29
    • 0031606279 scopus 로고    scopus 로고
    • Chronic leptin infusion increases arterial pressure
    • Shek EW, Brands MW, and Hall JE. Chronic leptin infusion increases arterial pressure. Hypertension 31: 409-414, 1998.
    • (1998) Hypertension , vol.31 , pp. 409-414
    • Shek, E.W.1    Brands, M.W.2    Hall, J.E.3
  • 30
    • 0041621613 scopus 로고    scopus 로고
    • Activation of the renal sympathetic nerve by leptin microinjection into the ventromedial hypothalamus in rats
    • Tanida M, Nagai K, and Kaneko H. Activation of the renal sympathetic nerve by leptin microinjection into the ventromedial hypothalamus in rats. In Vivo 17: 213-217, 2003.
    • (2003) In Vivo , vol.17 , pp. 213-217
    • Tanida, M.1    Nagai, K.2    Kaneko, H.3
  • 31
    • 0036085084 scopus 로고    scopus 로고
    • Forebrain renin-angiotensin system has a tonic excitatory influence on renal sympathetic nerve activity
    • Wei SG and Felder RB. Forebrain renin-angiotensin system has a tonic excitatory influence on renal sympathetic nerve activity. Am J Physiol Heart Circ Physiol 282: H890-H895, 2002.
    • (2002) Am J Physiol Heart Circ Physiol , vol.282
    • Wei, S.G.1    Felder, R.B.2
  • 32
    • 0027319108 scopus 로고
    • Increased neuropeptide-Y messenger ribonucleic acid (mRNA) and decreased neurotensin mRNA in the hypothalamus of the obese (ob/ob) mouse
    • Wilding JP, Gilbey SG, Bailey CJ, Batt RA, Williams G, Ghatei MA, and Bloom SR. Increased neuropeptide-Y messenger ribonucleic acid (mRNA) and decreased neurotensin mRNA in the hypothalamus of the obese (ob/ob) mouse. Endocrinology 132: 1939-1944, 1993.
    • (1993) Endocrinology , vol.132 , pp. 1939-1944
    • Wilding, J.P.1    Gilbey, S.G.2    Bailey, C.J.3    Batt, R.A.4    Williams, G.5    Ghatei, M.A.6    Bloom, S.R.7
  • 33
    • 0029949063 scopus 로고    scopus 로고
    • Leptin activation in hypothalamus
    • Woods AJ and Stock MJ. Leptin activation in hypothalamus. Nature 381: 745, 1996.
    • (1996) Nature , vol.381 , pp. 745
    • Woods, A.J.1    Stock, M.J.2
  • 34
    • 0942296208 scopus 로고    scopus 로고
    • Leptin activates hypothalamic paraventricular nucleus (PVN) neurons via the brain melanocortin system
    • Zhang ZH and Felder RB. Leptin activates hypothalamic paraventricular nucleus (PVN) neurons via the brain melanocortin system (Abstract). Soc Neurosci Abstr 27: 733, 2001.
    • (2001) Soc Neurosci Abstr , vol.27 , pp. 733
    • Zhang, Z.H.1    Felder, R.B.2
  • 35
    • 25044454138 scopus 로고    scopus 로고
    • Opposite effects of leptin and NPY on hypothalamic paraventricular nucleus (PVN) neurons
    • Zhang ZH and Felder RB. Opposite effects of leptin and NPY on hypothalamic paraventricular nucleus (PVN) neurons (Abstract). FASEB J 15: A77, 2001.
    • (2001) FASEB J , vol.15
    • Zhang, Z.H.1    Felder, R.B.2
  • 36
    • 0036304948 scopus 로고    scopus 로고
    • The renin-angiotensin-aldosterone system excites hypothalamic paraventricular nucleus neurons in heart failure
    • Zhang ZH, Francis J, Weiss RM, and Felder RB. The renin-angiotensin-aldosterone system excites hypothalamic paraventricular nucleus neurons in heart failure. Am J Physiol Heart Circ Physiol 283: H423-H433, 2002.
    • (2002) Am J Physiol Heart Circ Physiol , vol.283
    • Zhang, Z.H.1    Francis, J.2    Weiss, R.M.3    Felder, R.B.4
  • 37
    • 0037384479 scopus 로고    scopus 로고
    • Cardiovascular and renal sympathetic activation by blood-borne TNF-α in rat: The role of central prostaglandins
    • Zhang ZH, Wei SG, Francis J, and Felder RB. Cardiovascular and renal sympathetic activation by blood-borne TNF-α in rat: the role of central prostaglandins. Am J Physiol Regul Integr Comp Physiol 284: R916-R927, 2003.
    • (2003) Am J Physiol Regul Integr Comp Physiol , vol.284
    • Zhang, Z.H.1    Wei, S.G.2    Francis, J.3    Felder, R.B.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.