Effect of overexpression of human aldehyde dehydrogenase 2 in LLC-PK1 cells on glyceryl trinitrate biotransformation and cGMP accumulation

British Journal of Pharmacology

Volumn 168, Issue 4, 2013, Pages 978-987

  D'Souza, Y ^a   Ji, Y ^a   Bennett, B M ^a  

^a QUEEN S UNIVERSITY   (Canada)

Author keywords

aldehyde dehydrogenase; cGMP; glyceryl trinitrate; nitrate tolerance; NO

Indexed keywords

ALDEHYDE DEHYDROGENASE ISOENZYME 2; CYCLIC GMP; GLYCEROL 1,2 DINITRATE; GLYCERYL TRINITRATE; SMALL INTERFERING RNA;

ANIMAL CELL; ARTICLE; BIOACCUMULATION; CELL CULTURE; CONTROLLED STUDY; DRUG TRANSFORMATION; ENZYME ACTIVITY; NONHUMAN; NUCLEOTIDE METABOLISM; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEIN EXPRESSION;

ALDEHYDE DEHYDROGENASE; ANIMALS; CELL CULTURE TECHNIQUES; CYCLIC GMP; HUMANS; IMMUNOBLOTTING; LLC-PK1 CELLS; MICROSCOPY, CONFOCAL; MICROSCOPY, FLUORESCENCE; NITROGLYCERIN; RNA, SMALL INTERFERING; SWINE; TRANSFECTION;

EID: 84872933638     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1111/j.1476-5381.2012.02220.x     Document Type: Article

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