메뉴 건너뛰기




Volumn 64, Issue 5, 2003, Pages 1109-1116

Role of Mitochondrial Aldehyde Dehydrogenase in Nitrate Tolerance

Author keywords

[No Author keywords available]

Indexed keywords

1,1 DIETHYL 2 HYDROXY 2 NITROSOHYDRAZINE; ALDEHYDE DEHYDROGENASE ISOENZYME 2; CYANAMIDE; GLYCERYL TRINITRATE; HYDRAZINE DERIVATIVE; NITRATE; NITRIC OXIDE; PROPIONALDEHYDE; UNCLASSIFIED DRUG;

EID: 0142185107     PISSN: 0026895X     EISSN: None     Source Type: Journal    
DOI: 10.1124/mol.64.5.1109     Document Type: Article
Times cited : (72)

References (56)
  • 1
    • 0025748846 scopus 로고
    • Acute and chronic antianginal efficacy of continuous twenty-four-hour application of transdermal nitroglycerin. Steering Committee, Transdermal Nitroglycerin Cooperative Study
    • Anonymous (1991) Acute and chronic antianginal efficacy of continuous twenty-four-hour application of transdermal nitroglycerin. Steering Committee, Transdermal Nitroglycerin Cooperative Study. Am J Cardiol 68:1263-1273.
    • (1991) Am J Cardiol , vol.68 , pp. 1263-1273
  • 2
    • 0035822633 scopus 로고    scopus 로고
    • In vitro activation of soluble guanylyl cyclase and nitric oxide release: A comparison of NO-donors and NO-mimetics
    • Artz JD, Toader V, Zavorin SI, Bennett BM, and Thatcher GRJ (2001) In vitro activation of soluble guanylyl cyclase and nitric oxide release: a comparison of NO-donors and NO-mimetics. Biochemistry 40:9256-9264.
    • (2001) Biochemistry , vol.40 , pp. 9256-9264
    • Artz, J.D.1    Toader, V.2    Zavorin, S.I.3    Bennett, B.M.4    Thatcher, G.R.J.5
  • 4
    • 0022576564 scopus 로고
    • Requirement for reduced, unliganded hemoprotein for the hemoglobin-and myoglobin-mediated biotransformation of glyceryl trinitrate
    • Bennett BM, Kobus SM, Brien JF, Nakatsu K, and Marks GS (1986) Requirement for reduced, unliganded hemoprotein for the hemoglobin-and myoglobin-mediated biotransformation of glyceryl trinitrate. J Pharmacol Exp Ther 237:629-635.
    • (1986) J Pharmacol Exp Ther , vol.237 , pp. 629-635
    • Bennett, B.M.1    Kobus, S.M.2    Brien, J.F.3    Nakatsu, K.4    Marks, G.S.5
  • 5
    • 0024392917 scopus 로고
    • Relationship between biotransformation of glyceryl trinitrate and cyclic GMP accumulation in various cultured cell lines
    • Bennett BM, Leitman DC, Schröder H, Kawamoto JH, Nakatsu K, and Murad F (1989) Relationship between biotransformation of glyceryl trinitrate and cyclic GMP accumulation in various cultured cell lines. J Pharmacol Exp Ther 250:316-323.
    • (1989) J Pharmacol Exp Ther , vol.250 , pp. 316-323
    • Bennett, B.M.1    Leitman, D.C.2    Schröder, H.3    Kawamoto, J.H.4    Nakatsu, K.5    Murad, F.6
  • 6
    • 0142199177 scopus 로고
    • How does nitroglycerin induce vascular smooth muscle relaxation?
    • Bennett BM and Marks GS (1984) How does nitroglycerin induce vascular smooth muscle relaxation? Trends Pharmacol Sci 5:329-332.
    • (1984) Trends Pharmacol Sci , vol.5 , pp. 329-332
    • Bennett, B.M.1    Marks, G.S.2
  • 7
    • 0028260356 scopus 로고
    • Biotransformation of organic nitrates and vascular smooth muscle cell function
    • Bennett BM, McDonald BJ, Nigam R, and Simon WC (1994) Biotransformation of organic nitrates and vascular smooth muscle cell function. Trends Pharmacol Sci 15:245-249.
    • (1994) Trends Pharmacol Sci , vol.15 , pp. 245-249
    • Bennett, B.M.1    McDonald, B.J.2    Nigam, R.3    Simon, W.C.4
  • 8
    • 0023758976 scopus 로고
    • Effect of in vitro organic nitrate tolerance on relaxation, cyclic GMP accumulation and guanylate cyclase activation by glyceryl trinitrate and the enantiomers of isoidide dinitrate
    • Bennett BM, Schroder H, Hayward LD, Waldman SA, and Murad F (1988) Effect of in vitro organic nitrate tolerance on relaxation, cyclic GMP accumulation and guanylate cyclase activation by glyceryl trinitrate and the enantiomers of isoidide dinitrate. Circ Res 63:693-701.
    • (1988) Circ Res , vol.63 , pp. 693-701
    • Bennett, B.M.1    Schroder, H.2    Hayward, L.D.3    Waldman, S.A.4    Murad, F.5
  • 9
    • 0030571564 scopus 로고    scopus 로고
    • Inhibition of chicken liver carboxylesterase by activated carbonyls and carbonyl hydrates
    • Berndt MC, Bowles MR, King GJ, and Zerner B (1996) Inhibition of chicken liver carboxylesterase by activated carbonyls and carbonyl hydrates. Biochim Biophys Acta 1298:159-166.
    • (1996) Biochim Biophys Acta , vol.1298 , pp. 159-166
    • Berndt, M.C.1    Bowles, M.R.2    King, G.J.3    Zerner, B.4
  • 11
    • 0023928805 scopus 로고
    • Mechanism of glyceryl trinitrate-induced vasodilation. I. Relationship between drug biotransformation, tissue cyclic GMP elevation and relaxation of rabbit aorta
    • Brien JF, McLaughlin BE, Kobus SM, Kawamoto JH, Nakatsu K, and Marks GS (1988) Mechanism of glyceryl trinitrate-induced vasodilation. I. Relationship between drug biotransformation, tissue cyclic GMP elevation and relaxation of rabbit aorta. J Pharmacol Exp Ther 244:322-327.
    • (1988) J Pharmacol Exp Ther , vol.244 , pp. 322-327
    • Brien, J.F.1    McLaughlin, B.E.2    Kobus, S.M.3    Kawamoto, J.H.4    Nakatsu, K.5    Marks, G.S.6
  • 12
    • 0019322671 scopus 로고
    • Reactions of nitric oxide with cytochrome c oxidase
    • Brudvig GW, Stevens TH, and Chan SI (1980) Reactions of nitric oxide with cytochrome c oxidase. Biochemistry 19:5275-5285.
    • (1980) Biochemistry , vol.19 , pp. 5275-5285
    • Brudvig, G.W.1    Stevens, T.H.2    Chan, S.I.3
  • 13
    • 0037062518 scopus 로고    scopus 로고
    • Identification of the enzymatic mechanism of nitroglycerin bioactivation
    • Chen Z, Zhang J, and Stamler JS (2002) Identification of the enzymatic mechanism of nitroglycerin bioactivation. Proc Natl Acad Sci USA 99:8306-8311.
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 8306-8311
    • Chen, Z.1    Zhang, J.2    Stamler, J.S.3
  • 14
    • 0033064430 scopus 로고    scopus 로고
    • Tolerance induction by transdermal glyceryl trinitrate in rats
    • De la Lande IS, Stafford I, and Horowitz JD (1999) Tolerance induction by transdermal glyceryl trinitrate in rats. Eur J Pharmacol 374:71-75.
    • (1999) Eur J Pharmacol , vol.374 , pp. 71-75
    • De la Lande, I.S.1    Stafford, I.2    Horowitz, J.D.3
  • 15
    • 0032525919 scopus 로고    scopus 로고
    • Mechanisms of inhibition of aldehyde dehydrogenase by nitroxyl, the active metabolite of the alcohol deterrent agent cyanamide
    • DeMaster EG, Redfern B, and Nagasawa HT (1998) Mechanisms of inhibition of aldehyde dehydrogenase by nitroxyl, the active metabolite of the alcohol deterrent agent cyanamide. Biochem Pharmacol 55:2007-2015.
    • (1998) Biochem Pharmacol , vol.55 , pp. 2007-2015
    • DeMaster, E.G.1    Redfern, B.2    Nagasawa, H.T.3
  • 17
    • 0034696803 scopus 로고    scopus 로고
    • Reduction of organic nitrites to nitric oxide catalyzed by xanthine oxidase: Possible role in metabolism of nitrovasodilators
    • Doel JJ, Godber BL, Goult TA, Eisenthal R, and Harrison R (2000) Reduction of organic nitrites to nitric oxide catalyzed by xanthine oxidase: possible role in metabolism of nitrovasodilators. Biochem Biophys Res Commun 270:880-885.
    • (2000) Biochem Biophys Res Commun , vol.270 , pp. 880-885
    • Doel, J.J.1    Godber, B.L.2    Goult, T.A.3    Eisenthal, R.4    Harrison, R.5
  • 19
    • 0022992843 scopus 로고
    • Nitrosothiol and nitrate tolerance
    • Fung H-L and Poliszczuk R (1986) Nitrosothiol and nitrate tolerance. Z Kardiol 75:25-27.
    • (1986) Z Kardiol , vol.75 , pp. 25-27
    • Fung, H.-L.1    Poliszczuk, R.2
  • 20
    • 0034687716 scopus 로고    scopus 로고
    • Reaction of nitric oxide with the turnover intermediates of cytochrome c oxidase: Reaction pathway and functional effects
    • Giuffre A, Barone MC, Mastronicola D, D'Itri E, Sarti P, and Brunori M (2000) Reaction of nitric oxide with the turnover intermediates of cytochrome c oxidase: reaction pathway and functional effects. Biochemistry 39:15446-15453.
    • (2000) Biochemistry , vol.39 , pp. 15446-15453
    • Giuffre, A.1    Barone, M.C.2    Mastronicola, D.3    D'Itri, E.4    Sarti, P.5    Brunori, M.6
  • 21
    • 0016811999 scopus 로고
    • Glutathione S-transferase in the formation of cyanide from organic thiocyanates and as an organic nitrate reductase
    • Habig WH, Keen JH, and Jackoby WB (1975) Glutathione S-transferase in the formation of cyanide from organic thiocyanates and as an organic nitrate reductase. Biochem Biophys Res Commun 64:501-506.
    • (1975) Biochem Biophys Res Commun , vol.64 , pp. 501-506
    • Habig, W.H.1    Keen, J.H.2    Jackoby, W.B.3
  • 22
    • 0028070184 scopus 로고
    • Identification of novel glutathione conjugates of disulfiram and diethyldithiocarbamate in rat bile by liquid chromatography-tandem mass spectrometry. Evidence for metabolic activation of disulfiram in vivo
    • Jin L, Davis MR, Hu P, and Baillie TA (1994) Identification of novel glutathione conjugates of disulfiram and diethyldithiocarbamate in rat bile by liquid chromatography-tandem mass spectrometry. Evidence for metabolic activation of disulfiram in vivo. Chem Res Toxicol 7:526-533.
    • (1994) Chem Res Toxicol , vol.7 , pp. 526-533
    • Jin, L.1    Davis, M.R.2    Hu, P.3    Baillie, T.A.4
  • 23
    • 0033035767 scopus 로고    scopus 로고
    • Nitrite reductase activity is a novel function of mammalian mitochondria
    • Kozlov AV, Staniek K, and Nohl H (1999) Nitrite reductase activity is a novel function of mammalian mitochondria. FEBS Lett 454:127-130.
    • (1999) FEBS Lett , vol.454 , pp. 127-130
    • Kozlov, A.V.1    Staniek, K.2    Nohl, H.3
  • 24
    • 0035969873 scopus 로고    scopus 로고
    • In vivo inhibition of aldehyde dehydrogenase by disulfiram
    • Lipsky JJ, Shen ML, and Naylor S (2001) In vivo inhibition of aldehyde dehydrogenase by disulfiram. Chem Biol Interact 130-132:93-102.
    • (2001) Chem Biol Interact , vol.130-132 , pp. 93-102
    • Lipsky, J.J.1    Shen, M.L.2    Naylor, S.3
  • 25
    • 0021029588 scopus 로고
    • Inhibition of hepatic aldehyde dehydrogenases in the rat by calcium carbimide (calcium cyanamide)
    • Loomis CW and Brien JF (1983) Inhibition of hepatic aldehyde dehydrogenases in the rat by calcium carbimide (calcium cyanamide). Can J Physiol Pharmacol 61:1025-1034.
    • (1983) Can J Physiol Pharmacol , vol.61 , pp. 1025-1034
    • Loomis, C.W.1    Brien, J.F.2
  • 26
    • 0035902511 scopus 로고    scopus 로고
    • Old yellow enzyme: Reduction of nitrate esters, glycerin trinitrate and propylene 1,2-dinitrate
    • Meah Y, Brown BJ, Chakraborty S, and Massey V (2001) Old yellow enzyme: reduction of nitrate esters, glycerin trinitrate and propylene 1,2-dinitrate. Proc Natl Acad Sci USA 98:8560-8565.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 8560-8565
    • Meah, Y.1    Brown, B.J.2    Chakraborty, S.3    Massey, V.4
  • 27
    • 0025638838 scopus 로고
    • Cytochrome P-450-mediated biotransformation of organic nitrates
    • McDonald BJ and Bennett BM (1990) Cytochrome P-450-mediated biotransformation of organic nitrates. Can J Physiol Pharmacol 68:1552-1557.
    • (1990) Can J Physiol Pharmacol , vol.68 , pp. 1552-1557
    • McDonald, B.J.1    Bennett, B.M.2
  • 28
    • 0027463904 scopus 로고
    • Biotransformation of glyceryl trinitrate by rat aortic cytochrome P450
    • McDonald BJ and Bennett BM (1993) Biotransformation of glyceryl trinitrate by rat aortic cytochrome P450. Biochem Pharmacol 45:268-270.
    • (1993) Biochem Pharmacol , vol.45 , pp. 268-270
    • McDonald, B.J.1    Bennett, B.M.2
  • 29
    • 0028020180 scopus 로고
    • Inhibition of the biotransformation and pharmacological actions of glyceryl trinitrate by the flavoprotein inhibitor, diphenyleneiodonium sulfate
    • McGuire JJ, Anderson DJ, and Bennett BM (1994) Inhibition of the biotransformation and pharmacological actions of glyceryl trinitrate by the flavoprotein inhibitor, diphenyleneiodonium sulfate. J Pharmacol Exp Ther 271:708-714.
    • (1994) J Pharmacol Exp Ther , vol.271 , pp. 708-714
    • McGuire, J.J.1    Anderson, D.J.2    Bennett, B.M.3
  • 30
    • 0032189899 scopus 로고    scopus 로고
    • Inhibition of NADPH-cytochrome P450 reductase and glyceryl trinitrate biotransformation by diphenyleneiodonium sulfate
    • McGuire JJ, Anderson DJ, McDonald BJ, Narayanasami R, and Bennett BM (1998) Inhibition of NADPH-cytochrome P450 reductase and glyceryl trinitrate biotransformation by diphenyleneiodonium sulfate. Biochem Pharmacol 56:881-893.
    • (1998) Biochem Pharmacol , vol.56 , pp. 881-893
    • McGuire, J.J.1    Anderson, D.J.2    McDonald, B.J.3    Narayanasami, R.4    Bennett, B.M.5
  • 31
    • 0028086127 scopus 로고
    • Inactivation of human aldehyde dehydrogenase by isosorbide dinitrate
    • Mukerjee N and Pietruszko R (1994) Inactivation of human aldehyde dehydrogenase by isosorbide dinitrate. J Biol Chem 269:21664-21669.
    • (1994) J Biol Chem , vol.269 , pp. 21664-21669
    • Mukerjee, N.1    Pietruszko, R.2
  • 32
    • 0028799761 scopus 로고
    • Evidence for enhanced vascular superoxide anion production in nitrate tolerance: A novel mechanism of tolerance and cross tolerance
    • Münzel T, Snyegh H, Freeman BA, Tarpey MM, and Harrison DG (1995) Evidence for enhanced vascular superoxide anion production in nitrate tolerance: a novel mechanism of tolerance and cross tolerance. J Clin Investig 95:187-194.
    • (1995) J Clin Investig , vol.95 , pp. 187-194
    • Münzel, T.1    Snyegh, H.2    Freeman, B.A.3    Tarpey, M.M.4    Harrison, D.G.5
  • 33
    • 0035891628 scopus 로고    scopus 로고
    • Catalysis of NO production by a molybdoenzyme model
    • Murray J, Macartney D, and Thatcher GR (2001) Catalysis of NO production by a molybdoenzyme model. Org Lett 3:3635-3638.
    • (2001) Org Lett , vol.3 , pp. 3635-3638
    • Murray, J.1    Macartney, D.2    Thatcher, G.R.3
  • 34
    • 0015595425 scopus 로고
    • Mechanism of tolerance development to organic nitrates
    • Needleman P and Johnson EM Jr (1973) Mechanism of tolerance development to organic nitrates. J Pharmacol Exp Ther 184:709-715.
    • (1973) J Pharmacol Exp Ther , vol.184 , pp. 709-715
    • Needleman, P.1    Johnson E.M., Jr.2
  • 35
    • 0030426903 scopus 로고    scopus 로고
    • Isoform-specific biotransformation of glyceryl trinitrate by rat aortic glutathione S-transferases
    • Nigam R, Lee S-F, Anderson DJ, and Bennett BM (1996) Isoform-specific biotransformation of glyceryl trinitrate by rat aortic glutathione S-transferases. J Pharmacol Exp Ther 279:1527-1534.
    • (1996) J Pharmacol Exp Ther , vol.279 , pp. 1527-1534
    • Nigam, R.1    Lee, S.-F.2    Anderson, D.J.3    Bennett, B.M.4
  • 37
    • 0029062052 scopus 로고
    • Nitrate esters as inhibitors and substrates of aldehyde dehydrogenase
    • Pietruszko R, Mukerjee N, Blatter EE, and Lehmann T (1995) Nitrate esters as inhibitors and substrates of aldehyde dehydrogenase. Adv Exp Med Biol 372:25-34.
    • (1995) Adv Exp Med Biol , vol.372 , pp. 25-34
    • Pietruszko, R.1    Mukerjee, N.2    Blatter, E.E.3    Lehmann, T.4
  • 38
    • 0036902539 scopus 로고    scopus 로고
    • Effect of in vivo nitrate tolerance on the hypersensitivity to NO-donors after NO-synthase blockade
    • Ratz JD, Adams MA, and Bennett BM (2002) Effect of in vivo nitrate tolerance on the hypersensitivity to NO-donors after NO-synthase blockade. Can J Physiol Pharmacol 80:1106-1118.
    • (2002) Can J Physiol Pharmacol , vol.80 , pp. 1106-1118
    • Ratz, J.D.1    Adams, M.A.2    Bennett, B.M.3
  • 39
    • 0033771601 scopus 로고    scopus 로고
    • Endothelin receptor antagonism does not prevent the development of in vivo glyceryl trinitrate tolerance in the rat
    • Ratz JD, Fraser AB, Rees-Milton KJ, Adams MA, and Bennett BM (2000a) Endothelin receptor antagonism does not prevent the development of in vivo glyceryl trinitrate tolerance in the rat. J Pharmacol Exp Ther 295:578-585.
    • (2000) J Pharmacol Exp Ther , vol.295 , pp. 578-585
    • Ratz, J.D.1    Fraser, A.B.2    Rees-Milton, K.J.3    Adams, M.A.4    Bennett, B.M.5
  • 40
    • 0034091976 scopus 로고    scopus 로고
    • Effects of the flavoprotein inhibitor, diphenyleneiodonium sulfate, on ex vivo organic nitrate tolerance in the rat
    • Ratz JD, McGuire JJ, Anderson DJ, and Bennett BM (2000b) Effects of the flavoprotein inhibitor, diphenyleneiodonium sulfate, on ex vivo organic nitrate tolerance in the rat. J Pharmacol Exp Ther 293:569-577.
    • (2000) J Pharmacol Exp Ther , vol.293 , pp. 569-577
    • Ratz, J.D.1    McGuire, J.J.2    Anderson, D.J.3    Bennett, B.M.4
  • 44
    • 0032168108 scopus 로고    scopus 로고
    • Evaluation of the magnitude and rate of nitric oxide production from nitrite in biological systems
    • Samouilov A, Kuppusamy P, and Zweier JL (1998) Evaluation of the magnitude and rate of nitric oxide production from nitrite in biological systems. Arch Biochem Biophys 357:1-7.
    • (1998) Arch Biochem Biophys , vol.357 , pp. 1-7
    • Samouilov, A.1    Kuppusamy, P.2    Zweier, J.L.3
  • 46
    • 0034976054 scopus 로고    scopus 로고
    • Inhibition of purified pig and human liver retinyl ester hydrolase by pharmacologic agents
    • Schindler R (2001) Inhibition of purified pig and human liver retinyl ester hydrolase by pharmacologic agents. Lipids 36:543-548.
    • (2001) Lipids , vol.36 , pp. 543-548
    • Schindler, R.1
  • 47
    • 0024787770 scopus 로고
    • Biotransformation of glyceryl trinitrate and isosorbide dinitrate in vascular smooth muscle made tolerant to organic nitrates
    • Slack CJ, McLaughlin BE, Brien JF, Marks GS, and Nakatsu K (1989) Biotransformation of glyceryl trinitrate and isosorbide dinitrate in vascular smooth muscle made tolerant to organic nitrates. Can J Physiol Pharmacol 67:1381-1385.
    • (1989) Can J Physiol Pharmacol , vol.67 , pp. 1381-1385
    • Slack, C.J.1    McLaughlin, B.E.2    Brien, J.F.3    Marks, G.S.4    Nakatsu, K.5
  • 48
    • 0024517914 scopus 로고
    • Subcellular localization of aldehyde dehydrogenase isozymes in human liver
    • Takase S, Tsutsumi M, and Takada A (1989) Subcellular localization of aldehyde dehydrogenase isozymes in human liver. Gastroenterol Jpn 24:31-39.
    • (1989) Gastroenterol Jpn , vol.24 , pp. 31-39
    • Takase, S.1    Tsutsumi, M.2    Takada, A.3
  • 49
    • 0032382795 scopus 로고    scopus 로고
    • NO problem for nitroglycerin: Organic nitrate chemistry and therapy
    • Thatcher GRJ and Weldon H (1998) NO problem for nitroglycerin: organic nitrate chemistry and therapy. Chem Soc Rev 27:331-337.
    • (1998) Chem Soc Rev , vol.27 , pp. 331-337
    • Thatcher, G.R.J.1    Weldon, H.2
  • 50
    • 0015737202 scopus 로고
    • The subcellular distribution and properties of aldehyde dehydrogenases in rat liver
    • Tottmar SOC, Pettersson H, and Kiessling K-H (1973) The subcellular distribution and properties of aldehyde dehydrogenases in rat liver. Biochem J 135:577-586.
    • (1973) Biochem J , vol.135 , pp. 577-586
    • Tottmar, S.O.C.1    Pettersson, H.2    Kiessling, K.-H.3
  • 51
    • 0022353721 scopus 로고
    • Erythrocyte aldehyde dehydrogenase and disulfiram-like side effects of hypoglycemics and antianginals
    • Towell J, Garthwaite T, and Wang R (1985) Erythrocyte aldehyde dehydrogenase and disulfiram-like side effects of hypoglycemics and antianginals. Alcohol Clin Exp Res 9:438-442.
    • (1985) Alcohol Clin Exp Res , vol.9 , pp. 438-442
    • Towell, J.1    Garthwaite, T.2    Wang, R.3
  • 52
    • 0025357203 scopus 로고
    • Purification and characterization of glutathione transferases with an activity toward nitroglycerin from human aorta and heart. Multiplicity of the human class mu forms
    • Tsuchida S, Maki T, and Sato K (1990) Purification and characterization of glutathione transferases with an activity toward nitroglycerin from human aorta and heart. Multiplicity of the human class mu forms. J Biol Chem 265:7150-7157.
    • (1990) J Biol Chem , vol.265 , pp. 7150-7157
    • Tsuchida, S.1    Maki, T.2    Sato, K.3
  • 53
    • 0023818387 scopus 로고
    • Hepatic aldehyde dehydrogenase isoenzymes: Differences with respect to species
    • Tsutsumi M, Takada A, Takase S, and Sugata K (1988) Hepatic aldehyde dehydrogenase isoenzymes: differences with respect to species. Alcohol 5:33-38.
    • (1988) Alcohol , vol.5 , pp. 33-38
    • Tsutsumi, M.1    Takada, A.2    Takase, S.3    Sugata, K.4
  • 54
    • 0033824324 scopus 로고    scopus 로고
    • Polymorphisms of human aldehyde dehydrogenases. Consequences for drug metabolism and disease
    • Vasiliou V and Pappa A (2000) Polymorphisms of human aldehyde dehydrogenases. Consequences for drug metabolism and disease. Pharmacology 61:192-198.
    • (2000) Pharmacology , vol.61 , pp. 192-198
    • Vasiliou, V.1    Pappa, A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.