메뉴 건너뛰기




Volumn 314, Issue 3, 2008, Pages 509-529

TNFα acting on TNFR1 promotes breast cancer growth via p42/P44 MAPK, JNK, Akt and NF-κB-dependent pathways

Author keywords

Breast cancer; NF B; TNF ; TNF receptors

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PROTEIN KINASE B; STRESS ACTIVATED PROTEIN KINASE; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR RECEPTOR 1;

EID: 38349043768     PISSN: 00144827     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.yexcr.2007.10.005     Document Type: Article
Times cited : (126)

References (58)
  • 1
    • 0027274028 scopus 로고
    • Tumor necrosis factor alpha as an autocrine and paracrine growth factor for ovarian cancer: monokine induction of tumor cell proliferation and tumor necrosis factor alpha expression
    • Wu S., Boyer C.M., Whitaker R.S., Berchuck A., Wiener J.R., Weinberg J.B., and Bast Jr. R.C. Tumor necrosis factor alpha as an autocrine and paracrine growth factor for ovarian cancer: monokine induction of tumor cell proliferation and tumor necrosis factor alpha expression. Cancer Res. 53 (1993) 1939-1944
    • (1993) Cancer Res. , vol.53 , pp. 1939-1944
    • Wu, S.1    Boyer, C.M.2    Whitaker, R.S.3    Berchuck, A.4    Wiener, J.R.5    Weinberg, J.B.6    Bast Jr., R.C.7
  • 2
    • 0026673687 scopus 로고
    • Tumor necrosis factor receptors - structure and function
    • Rothe J., Gehr G., Loetscher H., and Lesslauer W. Tumor necrosis factor receptors - structure and function. Immunol. Res. 11 (1992) 81-90
    • (1992) Immunol. Res. , vol.11 , pp. 81-90
    • Rothe, J.1    Gehr, G.2    Loetscher, H.3    Lesslauer, W.4
  • 3
    • 0030298294 scopus 로고    scopus 로고
    • Dissection of TNF receptor 1 effector functions: JNK activation is not linked to apoptosis while NF-kappaB activation prevents cell death
    • Liu Z.G., Hsu H., Goeddel D.V., and Karin M. Dissection of TNF receptor 1 effector functions: JNK activation is not linked to apoptosis while NF-kappaB activation prevents cell death. Cell 87 (1996) 565-576
    • (1996) Cell , vol.87 , pp. 565-576
    • Liu, Z.G.1    Hsu, H.2    Goeddel, D.V.3    Karin, M.4
  • 4
    • 0028124428 scopus 로고
    • A novel family of putative signal transducers associated with the cytoplasmic domain of the 75 kDa tumor necrosis factor receptor
    • Rothe M., Wong S.C., Henzel W.J., and Goeddel D.V. A novel family of putative signal transducers associated with the cytoplasmic domain of the 75 kDa tumor necrosis factor receptor. Cell 78 (1994) 681-692
    • (1994) Cell , vol.78 , pp. 681-692
    • Rothe, M.1    Wong, S.C.2    Henzel, W.J.3    Goeddel, D.V.4
  • 6
    • 0029007855 scopus 로고
    • The TNF receptor 1-associated protein TRADD signals cell death and NF-kappa B activation
    • Hsu H., Xiong J., and Goeddel D.V. The TNF receptor 1-associated protein TRADD signals cell death and NF-kappa B activation. Cell 81 (1995) 495-504
    • (1995) Cell , vol.81 , pp. 495-504
    • Hsu, H.1    Xiong, J.2    Goeddel, D.V.3
  • 7
    • 0033517189 scopus 로고    scopus 로고
    • NF-kappaB activation by tumour necrosis factor requires the Akt serine-threonine kinase
    • Ozes O.N., Mayo L.D., Gustin J.A., Pfeffer S.R., Pfeffer L.M., and Donner D.B. NF-kappaB activation by tumour necrosis factor requires the Akt serine-threonine kinase. Nature 401 (1999) 82-85
    • (1999) Nature , vol.401 , pp. 82-85
    • Ozes, O.N.1    Mayo, L.D.2    Gustin, J.A.3    Pfeffer, S.R.4    Pfeffer, L.M.5    Donner, D.B.6
  • 8
    • 33745298519 scopus 로고    scopus 로고
    • Nuclear factor-kappaB in cancer development and progression
    • Karin M. Nuclear factor-kappaB in cancer development and progression. Nature 441 (2006) 431-436
    • (2006) Nature , vol.441 , pp. 431-436
    • Karin, M.1
  • 9
    • 0036771765 scopus 로고    scopus 로고
    • Two pathways to NF-kappaB
    • Pomerantz J.L., and Baltimore D. Two pathways to NF-kappaB. Mol. Cell 10 (2002) 693-695
    • (2002) Mol. Cell , vol.10 , pp. 693-695
    • Pomerantz, J.L.1    Baltimore, D.2
  • 10
    • 0033752746 scopus 로고    scopus 로고
    • Functional significance of MMP-9 in tumor necrosis factor-induced proliferation and branching morphogenesis of mammary epithelial cells
    • Lee P.P., Hwang J.J., Murphy G., and Ip M.M. Functional significance of MMP-9 in tumor necrosis factor-induced proliferation and branching morphogenesis of mammary epithelial cells. Endocrinology 141 (2000) 3764-3773
    • (2000) Endocrinology , vol.141 , pp. 3764-3773
    • Lee, P.P.1    Hwang, J.J.2    Murphy, G.3    Ip, M.M.4
  • 11
    • 0029850644 scopus 로고    scopus 로고
    • Tumor necrosis factor-alpha: a multifunctional regulator of mammary gland development
    • Varela L.M., and Ip M.M. Tumor necrosis factor-alpha: a multifunctional regulator of mammary gland development. Endocrinology 137 (1996) 4915-4924
    • (1996) Endocrinology , vol.137 , pp. 4915-4924
    • Varela, L.M.1    Ip, M.M.2
  • 12
    • 0033568358 scopus 로고    scopus 로고
    • Essential role of tumor necrosis factor alpha (TNF-alpha) in tumor promotion as revealed by TNF-alpha-deficient mice
    • Suganuma M., Okabe S., Marino M.W., Sakai A., Sueoka E., and Fujiki H. Essential role of tumor necrosis factor alpha (TNF-alpha) in tumor promotion as revealed by TNF-alpha-deficient mice. Cancer Res. 59 (1999) 4516-4518
    • (1999) Cancer Res. , vol.59 , pp. 4516-4518
    • Suganuma, M.1    Okabe, S.2    Marino, M.W.3    Sakai, A.4    Sueoka, E.5    Fujiki, H.6
  • 14
    • 0034677776 scopus 로고    scopus 로고
    • HER-2/neu blocks tumor necrosis factor-induced apoptosis via the Akt/NF-kappaB pathway
    • Zhou B.P., Hu M.C., Miller S.A., Yu Z., Xia W., Lin S.Y., and Hung M.C. HER-2/neu blocks tumor necrosis factor-induced apoptosis via the Akt/NF-kappaB pathway. J. Biol. Chem. 275 (2000) 8027-8031
    • (2000) J. Biol. Chem. , vol.275 , pp. 8027-8031
    • Zhou, B.P.1    Hu, M.C.2    Miller, S.A.3    Yu, Z.4    Xia, W.5    Lin, S.Y.6    Hung, M.C.7
  • 16
    • 0034744035 scopus 로고    scopus 로고
    • TNFalpha induces NFkappaB/p50 in association with the growth and morphogenesis of normal and transformed rat mammary epithelial cells
    • Varela L.M., Stangle-Castor N.C., Shoemaker S.F., Shea-Eaton W.K., and Ip M.M. TNFalpha induces NFkappaB/p50 in association with the growth and morphogenesis of normal and transformed rat mammary epithelial cells. J. Cell. Physiol. 188 (2001) 120-131
    • (2001) J. Cell. Physiol. , vol.188 , pp. 120-131
    • Varela, L.M.1    Stangle-Castor, N.C.2    Shoemaker, S.F.3    Shea-Eaton, W.K.4    Ip, M.M.5
  • 17
    • 0035857473 scopus 로고    scopus 로고
    • Interactions of vitamin D analogue CB1093, TNFalpha and ceramide on breast cancer cell apoptosis
    • Pirianov G., and Colston K.W. Interactions of vitamin D analogue CB1093, TNFalpha and ceramide on breast cancer cell apoptosis. Mol. Cell. Endocrinol. 172 (2001) 69-78
    • (2001) Mol. Cell. Endocrinol. , vol.172 , pp. 69-78
    • Pirianov, G.1    Colston, K.W.2
  • 18
    • 3142717695 scopus 로고    scopus 로고
    • Inhibition of in vivo breast cancer growth by antisense oligodeoxynucleotides to type I insulin-like growth factor receptor mRNA involves inactivation of ErbBs, PI-3K/Akt and p42/p44 MAPK signaling pathways but not modulation of progesterone receptor activity
    • Salatino M., Schillaci R., Proietti C.J., Carnevale R., Frahm I., Molinolo A.A., Iribarren A., Charreau E.H., and Elizalde P.V. Inhibition of in vivo breast cancer growth by antisense oligodeoxynucleotides to type I insulin-like growth factor receptor mRNA involves inactivation of ErbBs, PI-3K/Akt and p42/p44 MAPK signaling pathways but not modulation of progesterone receptor activity. Oncogene 23 (2004) 5161-5174
    • (2004) Oncogene , vol.23 , pp. 5161-5174
    • Salatino, M.1    Schillaci, R.2    Proietti, C.J.3    Carnevale, R.4    Frahm, I.5    Molinolo, A.A.6    Iribarren, A.7    Charreau, E.H.8    Elizalde, P.V.9
  • 20
    • 0022975342 scopus 로고
    • Induction of mammary adenocarcinomas by medroxyprogesterone acetate in BALB/c female mice
    • Lanari C., Molinolo A.A., and Pasqualini C.D. Induction of mammary adenocarcinomas by medroxyprogesterone acetate in BALB/c female mice. Cancer Lett. 33 (1986) 215-223
    • (1986) Cancer Lett. , vol.33 , pp. 215-223
    • Lanari, C.1    Molinolo, A.A.2    Pasqualini, C.D.3
  • 21
    • 0035870130 scopus 로고    scopus 로고
    • Mechanisms of cell cycle arrest in response to TGF-beta in progestin-dependent and -independent growth of mammary tumors
    • Salatino M., Labriola L., Schillaci R., Charreau E.H., and Elizalde P.V. Mechanisms of cell cycle arrest in response to TGF-beta in progestin-dependent and -independent growth of mammary tumors. Exp. Cell Res. 265 (2001) 152-166
    • (2001) Exp. Cell Res. , vol.265 , pp. 152-166
    • Salatino, M.1    Labriola, L.2    Schillaci, R.3    Charreau, E.H.4    Elizalde, P.V.5
  • 22
    • 0035879752 scopus 로고    scopus 로고
    • Sensitization to TNF-induced apoptosis by 1,25-dihydroxy vitamin D(3) involves up-regulation of the TNF receptor 1 and cathepsin B
    • Mathiasen I.S., Hansen C.M., Foghsgaard L., and Jaattela M. Sensitization to TNF-induced apoptosis by 1,25-dihydroxy vitamin D(3) involves up-regulation of the TNF receptor 1 and cathepsin B. Int. J. Cancer 93 (2001) 224-231
    • (2001) Int. J. Cancer , vol.93 , pp. 224-231
    • Mathiasen, I.S.1    Hansen, C.M.2    Foghsgaard, L.3    Jaattela, M.4
  • 23
    • 0035813225 scopus 로고    scopus 로고
    • Identification of tumor necrosis factor (TNF) amino acids crucial for binding to the murine p75 TNF receptor and construction of receptor-selective mutants
    • Ameloot P., Fiers W., De Bleser P., Ware C.F., Vandenabeele P., and Brouckaert P. Identification of tumor necrosis factor (TNF) amino acids crucial for binding to the murine p75 TNF receptor and construction of receptor-selective mutants. J. Biol. Chem. 276 (2001) 37426-37430
    • (2001) J. Biol. Chem. , vol.276 , pp. 37426-37430
    • Ameloot, P.1    Fiers, W.2    De Bleser, P.3    Ware, C.F.4    Vandenabeele, P.5    Brouckaert, P.6
  • 24
    • 0028063591 scopus 로고
    • Characterization of two monoclonal antibodies directed against bactericidal/permeability-increasing protein
    • Dentener M.A., Smit F.T., Francot G.J., and Buurman W.A. Characterization of two monoclonal antibodies directed against bactericidal/permeability-increasing protein. J. Infect. Dis. 170 (1994) 1483-1489
    • (1994) J. Infect. Dis. , vol.170 , pp. 1483-1489
    • Dentener, M.A.1    Smit, F.T.2    Francot, G.J.3    Buurman, W.A.4
  • 25
    • 0029073322 scopus 로고
    • Effect of medroxyprogesterone acetate (MPA) and serum factors on cell proliferation in primary cultures of an MPA-induced mammary adenocarcinoma
    • Dran G., Luthy I.A., Molinolo A.A., Montecchia F., Charreau E.H., Pasqualini C.D., and Lanari C. Effect of medroxyprogesterone acetate (MPA) and serum factors on cell proliferation in primary cultures of an MPA-induced mammary adenocarcinoma. Breast Cancer Res. Treat. 35 (1995) 173-186
    • (1995) Breast Cancer Res. Treat. , vol.35 , pp. 173-186
    • Dran, G.1    Luthy, I.A.2    Molinolo, A.A.3    Montecchia, F.4    Charreau, E.H.5    Pasqualini, C.D.6    Lanari, C.7
  • 27
    • 0028961574 scopus 로고
    • Monoclonal antibodies specific for murine p55 and p75 tumor necrosis factor receptors: identification of a novel in vivo role for p75
    • Sheehan K.C., Pinckard J.K., Arthur C.D., Dehner L.P., Goeddel D.V., and Schreiber R.D. Monoclonal antibodies specific for murine p55 and p75 tumor necrosis factor receptors: identification of a novel in vivo role for p75. J. Exp. Med. 181 (1995) 607-617
    • (1995) J. Exp. Med. , vol.181 , pp. 607-617
    • Sheehan, K.C.1    Pinckard, J.K.2    Arthur, C.D.3    Dehner, L.P.4    Goeddel, D.V.5    Schreiber, R.D.6
  • 28
    • 0030772376 scopus 로고    scopus 로고
    • Novel inhibitors of cytokine-induced IkappaBalpha phosphorylation and endothelial cell adhesion molecule expression show anti-inflammatory effects in vivo
    • Pierce J.W., Schoenleber R., Jesmok G., Best J., Moore S.A., Collins T., and Gerritsen M.E. Novel inhibitors of cytokine-induced IkappaBalpha phosphorylation and endothelial cell adhesion molecule expression show anti-inflammatory effects in vivo. J. Biol. Chem. 272 (1997) 21096-21103
    • (1997) J. Biol. Chem. , vol.272 , pp. 21096-21103
    • Pierce, J.W.1    Schoenleber, R.2    Jesmok, G.3    Best, J.4    Moore, S.A.5    Collins, T.6    Gerritsen, M.E.7
  • 29
    • 0036009115 scopus 로고    scopus 로고
    • NF-kappaB at the crossroads of life and death
    • Karin M., and Lin A. NF-kappaB at the crossroads of life and death. Nat. Immunol. 3 (2002) 221-227
    • (2002) Nat. Immunol. , vol.3 , pp. 221-227
    • Karin, M.1    Lin, A.2
  • 30
    • 33644773386 scopus 로고    scopus 로고
    • TNF-alpha enhances estrogen-induced cell proliferation of estrogen-dependent breast tumor cells through a complex containing nuclear factor-kappa B
    • Rubio M.F., Werbajh S., Cafferata E.G., Quaglino A., Colo G.P., Nojek I.M., Kordon E.C., Nahmod V.E., and Costas M.A. TNF-alpha enhances estrogen-induced cell proliferation of estrogen-dependent breast tumor cells through a complex containing nuclear factor-kappa B. Oncogene 25 (2006) 1367-1377
    • (2006) Oncogene , vol.25 , pp. 1367-1377
    • Rubio, M.F.1    Werbajh, S.2    Cafferata, E.G.3    Quaglino, A.4    Colo, G.P.5    Nojek, I.M.6    Kordon, E.C.7    Nahmod, V.E.8    Costas, M.A.9
  • 31
    • 0029855760 scopus 로고    scopus 로고
    • Tumor necrosis factor receptors (Tnfr) in mouse fibroblasts deficient in Tnfr1 or Tnfr2 are signaling competent and activate the mitogen-activated protein kinase pathway with differential kinetics
    • Kalb A., Bluethmann H., Moore M.W., and Lesslauer W. Tumor necrosis factor receptors (Tnfr) in mouse fibroblasts deficient in Tnfr1 or Tnfr2 are signaling competent and activate the mitogen-activated protein kinase pathway with differential kinetics. J. Biol. Chem. 271 (1996) 28097-28104
    • (1996) J. Biol. Chem. , vol.271 , pp. 28097-28104
    • Kalb, A.1    Bluethmann, H.2    Moore, M.W.3    Lesslauer, W.4
  • 32
    • 0035943617 scopus 로고    scopus 로고
    • Genetic deletion of the tumor necrosis factor receptor p60 or p80 abrogates ligand-mediated activation of nuclear factor-kappa B and of mitogen-activated protein kinases in macrophages
    • Mukhopadhyay A., Suttles J., Stout R.D., and Aggarwal B.B. Genetic deletion of the tumor necrosis factor receptor p60 or p80 abrogates ligand-mediated activation of nuclear factor-kappa B and of mitogen-activated protein kinases in macrophages. J. Biol. Chem. 276 (2001) 31906-31912
    • (2001) J. Biol. Chem. , vol.276 , pp. 31906-31912
    • Mukhopadhyay, A.1    Suttles, J.2    Stout, R.D.3    Aggarwal, B.B.4
  • 33
    • 0033563648 scopus 로고    scopus 로고
    • Conversion of TNF alpha from antiproliferative to proliferative ligand in mouse intestinal epithelial cells by regulating mitogen-activated protein kinase
    • Kaiser G.C., Yan F., and Polk D.B. Conversion of TNF alpha from antiproliferative to proliferative ligand in mouse intestinal epithelial cells by regulating mitogen-activated protein kinase. Exp. Cell Res. 249 (1999) 349-358
    • (1999) Exp. Cell Res. , vol.249 , pp. 349-358
    • Kaiser, G.C.1    Yan, F.2    Polk, D.B.3
  • 35
    • 0035504199 scopus 로고    scopus 로고
    • Type II tumour necrosis factor-alpha receptor (TNFR2) activates c-Jun N-terminal kinase (JNK) but not mitogen-activated protein kinase (MAPK) or p38 MAPK pathways
    • Jupp O.J., McFarlane S.M., Anderson H.M., Littlejohn A.F., Mohamed A.A., MacKay R.H., Vandenabeele P., and MacEwan D.J. Type II tumour necrosis factor-alpha receptor (TNFR2) activates c-Jun N-terminal kinase (JNK) but not mitogen-activated protein kinase (MAPK) or p38 MAPK pathways. Biochem. J. 359 (2001) 525-535
    • (2001) Biochem. J. , vol.359 , pp. 525-535
    • Jupp, O.J.1    McFarlane, S.M.2    Anderson, H.M.3    Littlejohn, A.F.4    Mohamed, A.A.5    MacKay, R.H.6    Vandenabeele, P.7    MacEwan, D.J.8
  • 36
    • 0036882166 scopus 로고    scopus 로고
    • The absence of NF-kappaB-mediated inhibition of c-Jun N-terminal kinase activation contributes to tumor necrosis factor alpha-induced apoptosis
    • Tang F., Tang G., Xiang J., Dai Q., Rosner M.R., and Lin A. The absence of NF-kappaB-mediated inhibition of c-Jun N-terminal kinase activation contributes to tumor necrosis factor alpha-induced apoptosis. Mol. Cell. Biol. 22 (2002) 8571-8579
    • (2002) Mol. Cell. Biol. , vol.22 , pp. 8571-8579
    • Tang, F.1    Tang, G.2    Xiang, J.3    Dai, Q.4    Rosner, M.R.5    Lin, A.6
  • 39
    • 0035930905 scopus 로고    scopus 로고
    • Alternative splicing variants of c-FLIP transduce the differential signal through the Raf or TRAF2 in TNF-induced cell proliferation
    • Park S.J., Kim Y.Y., Ju J.W., Han B.G., Park S.I., and Park B.J. Alternative splicing variants of c-FLIP transduce the differential signal through the Raf or TRAF2 in TNF-induced cell proliferation. Biochem. Biophys. Res. Commun. 289 (2001) 1205-1210
    • (2001) Biochem. Biophys. Res. Commun. , vol.289 , pp. 1205-1210
    • Park, S.J.1    Kim, Y.Y.2    Ju, J.W.3    Han, B.G.4    Park, S.I.5    Park, B.J.6
  • 40
    • 0034705271 scopus 로고    scopus 로고
    • A novel mechanism of TRAF signaling revealed by structural and functional analyses of the TRADD-TRAF2 interaction
    • Park Y.C., Ye H., Hsia C., Segal D., Rich R.L., Liou H.C., Myszka D.G., and Wu H. A novel mechanism of TRAF signaling revealed by structural and functional analyses of the TRADD-TRAF2 interaction. Cell 101 (2000) 777-787
    • (2000) Cell , vol.101 , pp. 777-787
    • Park, Y.C.1    Ye, H.2    Hsia, C.3    Segal, D.4    Rich, R.L.5    Liou, H.C.6    Myszka, D.G.7    Wu, H.8
  • 41
    • 0027301244 scopus 로고
    • Ligand passing: the 75-kDa tumor necrosis factor (TNF) receptor recruits TNF for signaling by the 55-kDa TNF receptor
    • Tartaglia L.A., Pennica D., and Goeddel D.V. Ligand passing: the 75-kDa tumor necrosis factor (TNF) receptor recruits TNF for signaling by the 55-kDa TNF receptor. J. Biol. Chem. 268 (1993) 18542-18548
    • (1993) J. Biol. Chem. , vol.268 , pp. 18542-18548
    • Tartaglia, L.A.1    Pennica, D.2    Goeddel, D.V.3
  • 42
    • 33748291392 scopus 로고    scopus 로고
    • Role of tumor necrosis factor-alpha and its receptors in human benign breast lesions and tumors (in situ and infiltrative)
    • Garcia-Tunon I., Ricote M., Ruiz A., Fraile B., Paniagua R., and Royuela M. Role of tumor necrosis factor-alpha and its receptors in human benign breast lesions and tumors (in situ and infiltrative). Cancer Sci. 97 (2006) 1044-1049
    • (2006) Cancer Sci. , vol.97 , pp. 1044-1049
    • Garcia-Tunon, I.1    Ricote, M.2    Ruiz, A.3    Fraile, B.4    Paniagua, R.5    Royuela, M.6
  • 43
    • 33750432183 scopus 로고    scopus 로고
    • Nuclear factor-kappaB and inhibitor of kappaB kinase pathways in oncogenic initiation and progression
    • Basseres D.S., and Baldwin A.S. Nuclear factor-kappaB and inhibitor of kappaB kinase pathways in oncogenic initiation and progression. Oncogene 25 (2006) 6817-6830
    • (2006) Oncogene , vol.25 , pp. 6817-6830
    • Basseres, D.S.1    Baldwin, A.S.2
  • 44
    • 0037181492 scopus 로고    scopus 로고
    • Differential activation of nuclear factor-kappaB by tumour necrosis factor receptor subtypes. TNFR1 predominates whereas TNFR2 activates transcription poorly
    • McFarlane S.M., Pashmi G., Connell M.C., Littlejohn A.F., Tucker S.J., Vandenabeele P., and MacEwan D.J. Differential activation of nuclear factor-kappaB by tumour necrosis factor receptor subtypes. TNFR1 predominates whereas TNFR2 activates transcription poorly. FEBS Lett. 515 (2002) 119-126
    • (2002) FEBS Lett. , vol.515 , pp. 119-126
    • McFarlane, S.M.1    Pashmi, G.2    Connell, M.C.3    Littlejohn, A.F.4    Tucker, S.J.5    Vandenabeele, P.6    MacEwan, D.J.7
  • 45
    • 0030587125 scopus 로고    scopus 로고
    • Differential activation of the nuclear factor-kappa B by TNF muteins specific for the p60 and p80 TNF receptors
    • Chainy G.B., Singh S., Raju U., and Aggarwal B.B. Differential activation of the nuclear factor-kappa B by TNF muteins specific for the p60 and p80 TNF receptors. J. Immunol. 157 (1996) 2410-2417
    • (1996) J. Immunol. , vol.157 , pp. 2410-2417
    • Chainy, G.B.1    Singh, S.2    Raju, U.3    Aggarwal, B.B.4
  • 46
    • 0032055981 scopus 로고    scopus 로고
    • Overexpression of the p80 TNF receptor leads to TNF-dependent apoptosis, nuclear factor-kappa B activation, and c-Jun kinase activation
    • Haridas V., Darnay B.G., Natarajan K., Heller R., and Aggarwal B.B. Overexpression of the p80 TNF receptor leads to TNF-dependent apoptosis, nuclear factor-kappa B activation, and c-Jun kinase activation. J. Immunol. 160 (1998) 3152-3162
    • (1998) J. Immunol. , vol.160 , pp. 3152-3162
    • Haridas, V.1    Darnay, B.G.2    Natarajan, K.3    Heller, R.4    Aggarwal, B.B.5
  • 48
    • 11144265329 scopus 로고    scopus 로고
    • Involvement of p42/p44 MAPK, JNK, and NF-kappaB in IL-1beta-induced ICAM-1 expression in human pulmonary epithelial cells
    • Lin F.S., Lin C.C., Chien C.S., Luo S.F., and Yang C.M. Involvement of p42/p44 MAPK, JNK, and NF-kappaB in IL-1beta-induced ICAM-1 expression in human pulmonary epithelial cells. J. Cell Physiol 202 (2005) 464-473
    • (2005) J. Cell Physiol , vol.202 , pp. 464-473
    • Lin, F.S.1    Lin, C.C.2    Chien, C.S.3    Luo, S.F.4    Yang, C.M.5
  • 49
    • 0035379555 scopus 로고    scopus 로고
    • Akt stimulates the transactivation potential of the RelA/p65 Subunit of NF-kappa B through utilization of the Ikappa B kinase and activation of the mitogen-activated protein kinase p38
    • Madrid L.V., Mayo M.W., Reuther J.Y., and Baldwin Jr. A.S. Akt stimulates the transactivation potential of the RelA/p65 Subunit of NF-kappa B through utilization of the Ikappa B kinase and activation of the mitogen-activated protein kinase p38. J. Biol. Chem. 276 (2001) 18934-18940
    • (2001) J. Biol. Chem. , vol.276 , pp. 18934-18940
    • Madrid, L.V.1    Mayo, M.W.2    Reuther, J.Y.3    Baldwin Jr., A.S.4
  • 50
    • 0037039665 scopus 로고    scopus 로고
    • Distinct roles of the Ikappa B kinase alpha and beta subunits in liberating nuclear factor kappa B (NF-kappa B) from Ikappa B and in phosphorylating the p65 subunit of NF-kappa B
    • Sizemore N., Lerner N., Dombrowski N., Sakurai H., and Stark G.R. Distinct roles of the Ikappa B kinase alpha and beta subunits in liberating nuclear factor kappa B (NF-kappa B) from Ikappa B and in phosphorylating the p65 subunit of NF-kappa B. J. Biol. Chem. 277 (2002) 3863-3869
    • (2002) J. Biol. Chem. , vol.277 , pp. 3863-3869
    • Sizemore, N.1    Lerner, N.2    Dombrowski, N.3    Sakurai, H.4    Stark, G.R.5
  • 51
    • 0035963435 scopus 로고    scopus 로고
    • Specific protection against breast cancers by cyclin D1 ablation
    • Yu Q., Geng Y., and Sicinski P. Specific protection against breast cancers by cyclin D1 ablation. Nature 411 (2001) 1017-1021
    • (2001) Nature , vol.411 , pp. 1017-1021
    • Yu, Q.1    Geng, Y.2    Sicinski, P.3
  • 52
    • 0032588170 scopus 로고    scopus 로고
    • NF-kappaB function in growth control: regulation of cyclin D1 expression and G0/G1-to-S-phase transition
    • Hinz M., Krappmann D., Eichten A., Heder A., Scheidereit C., and Strauss M. NF-kappaB function in growth control: regulation of cyclin D1 expression and G0/G1-to-S-phase transition. Mol. Cell. Biol. 19 (1999) 2690-2698
    • (1999) Mol. Cell. Biol. , vol.19 , pp. 2690-2698
    • Hinz, M.1    Krappmann, D.2    Eichten, A.3    Heder, A.4    Scheidereit, C.5    Strauss, M.6
  • 54
    • 0025293539 scopus 로고
    • Progestin regulation of cellular proliferation
    • Clarke C.L., and Sutherland R.L. Progestin regulation of cellular proliferation. Endocr. Rev. 11 (1990) 266-301
    • (1990) Endocr. Rev. , vol.11 , pp. 266-301
    • Clarke, C.L.1    Sutherland, R.L.2
  • 55
    • 4544224979 scopus 로고    scopus 로고
    • Inhibition of NF-kappaB in cancer cells converts inflammation-induced tumor growth mediated by TNFalpha to TRAIL-mediated tumor regression
    • Luo J.L., Maeda S., Hsu L.C., Yagita H., and Karin M. Inhibition of NF-kappaB in cancer cells converts inflammation-induced tumor growth mediated by TNFalpha to TRAIL-mediated tumor regression. Cancer Cells 6 (2004) 297-305
    • (2004) Cancer Cells , vol.6 , pp. 297-305
    • Luo, J.L.1    Maeda, S.2    Hsu, L.C.3    Yagita, H.4    Karin, M.5
  • 57
    • 12944273470 scopus 로고    scopus 로고
    • Targeting of nuclear factor kappaB pathways by dehydroxymethylepoxyquinomicin, a novel inhibitor of breast carcinomas: antitumor and antiangiogenic potential in vivo
    • Matsumoto G., Namekawa J., Muta M., Nakamura T., Bando H., Tohyama K., Toi M., and Umezawa K. Targeting of nuclear factor kappaB pathways by dehydroxymethylepoxyquinomicin, a novel inhibitor of breast carcinomas: antitumor and antiangiogenic potential in vivo. Clin. Cancer Res. 11 (2005) 1287-1293
    • (2005) Clin. Cancer Res. , vol.11 , pp. 1287-1293
    • Matsumoto, G.1    Namekawa, J.2    Muta, M.3    Nakamura, T.4    Bando, H.5    Tohyama, K.6    Toi, M.7    Umezawa, K.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.