Functional heterogeneity of breast fibroblasts is defined by a prostaglandin secretory phenotype that promotes expansion of cancer-stem like cells

PLoS ONE

Volumn 6, Issue 9, 2011, Pages

  Rudnick, Jenny A ^a   Arendt, Lisa M ^b   Klebba, Ina ^b   Hinds, John W ^b   Iyer, Vandana ^b   Gupta, Piyush B ^c   Naber, Stephen P ^b   Kuperwasser, Charlotte ^a,b  

^a TUFTS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b TUFTS MEDICAL CENTER   (United States)

^c WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 6; PROSTAGLANDIN E2;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BREAST CARCINOMA; BREAST RECONSTRUCTION; CANCER GROWTH; CANCER STEM CELL; CANCER STEM LIKE CELL; CANCER TISSUE; CELL COUNT; CELL FUNCTION; CELL HETEROGENEITY; CELL ISOLATION; CELL LEVEL; CELL POPULATION; CONTROLLED STUDY; CYTOKINE RELEASE; FEMALE; FIBROBLAST; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VIVO STUDY; MOUSE; NONHUMAN; PROSTAGLANDIN RELEASE; PROTEIN EXPRESSION; STEM CELL EXPANSION; TUMOR PROMOTION; ANIMAL; BREAST; BREAST TUMOR; CELL SEPARATION; METABOLISM; PATHOLOGY; PHENOTYPE; SECRETION; SIGNAL TRANSDUCTION; TUMOR CELL LINE;

ANIMALS; BREAST; BREAST NEOPLASMS; CELL LINE, TUMOR; CELL SEPARATION; DINOPROSTONE; FEMALE; FIBROBLASTS; HUMANS; INTERLEUKIN-6; MAMMAPLASTY; MICE; NEOPLASTIC STEM CELLS; PHENOTYPE; SIGNAL TRANSDUCTION;

EID: 80053012538     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0024605     Document Type: Article

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