Biosynthetic multitasking facilitates thalassospiramide structural diversity in marine bacteria

Journal of the American Chemical Society

Volumn 135, Issue 3, 2013, Pages 1155-1162

  Ross, Avena C ^a   Xu, Ying ^b   Lu, Liang ^b   Kersten, Roland D ^a   Shao, Zongze ^c   Al Suwailem, Abdulaziz M ^d   Dorrestein, Pieter C ^a,e   Qian, Pei Yuan ^b   Moore, Bradley S ^a,e  

^a UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^b HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Hong Kong)

^c Third Institute of Oceanography   (China)

^d KING ABDULLAH UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Saudi Arabia)

^e UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACID ACTIVATION; BIOCHEMICAL ANALYSIS; BIOINFORMATICS ANALYSIS; CALPAINS; COMPLEX SEQUENCES; CYCLIC LIPOPEPTIDES; GENE CLUSTERS; GENOMIC SEQUENCE; MARINE BACTERIUM; MULTIMODULE; N-TERMINALS; NONRIBOSOMAL PEPTIDE SYNTHETASES; PROTEASE INHIBITOR; PROTEOBACTERIUM; SIDE-CHAINS; STRUCTURAL DIVERSITY; SYNTHASES;

ACTIVATION ANALYSIS; AMINO ACIDS; BACTERIA; BIOINFORMATICS; ENZYME ACTIVITY; SUBSTRATES;

BIOSYNTHESIS;

CALPAIN 1; IMMUNOSUPPRESSIVE AGENT; LIPOPEPTIDE; NATURAL PRODUCT; THALASSOSPIRAMIDE A; THALASSOSPIRAMIDE A1; THALASSOSPIRAMIDE A2; THALASSOSPIRAMIDE A3; THALASSOSPIRAMIDE A4; THALASSOSPIRAMIDE A5; THALASSOSPIRAMIDE B; THALASSOSPIRAMIDE B1; THALASSOSPIRAMIDE B2; THALASSOSPIRAMIDE C; THALASSOSPIRAMIDE C1; THALASSOSPIRAMIDE D; THALASSOSPIRAMIDE D1; THALASSOSPIRAMIDE DERIVATIVE; THALASSOSPIRAMIDE E; THALASSOSPIRAMIDE E1; THALASSOSPIRAMIDE F; UNCLASSIFIED DRUG;

ALPHAPROTEOBACTERIA; ARTICLE; DRUG ISOLATION; DRUG STRUCTURE; GENE LOCUS; GENE SEQUENCE; GENOME; NONHUMAN; THALASSOSPIRA; TISTRELLA;

AQUATIC ORGANISMS; CALPAIN; COMPUTATIONAL BIOLOGY; GLYCOPROTEINS; HUMANS; MOLECULAR CONFORMATION; PEPTIDES, CYCLIC; RHODOSPIRILLACEAE; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84872808339     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/ja3119674     Document Type: Article

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