-
2
-
-
0032438210
-
Tuberous sclerosis complex consensus conference: revised clinical diagnostic criteria
-
Roach ES, Gomez MR, Northrup H, (1998) Tuberous sclerosis complex consensus conference: revised clinical diagnostic criteria. J Child Neurol 13: 624-628.
-
(1998)
J Child Neurol
, vol.13
, pp. 624-628
-
-
Roach, E.S.1
Gomez, M.R.2
Northrup, H.3
-
3
-
-
77949882117
-
The tuberous sclerosis complex
-
Orlova KA, Crino PB, (2010) The tuberous sclerosis complex. Ann NY Acad Sci 1184: 87-105.
-
(2010)
Ann NY Acad Sci
, vol.1184
, pp. 87-105
-
-
Orlova, K.A.1
Crino, P.B.2
-
4
-
-
0036712905
-
Tsc tumour suppressor proteins antagonize amino-acid-TOR signalling
-
Gao X, Zhang Y, Arrazola P, Hino O, Kobayashi T, et al. (2002) Tsc tumour suppressor proteins antagonize amino-acid-TOR signalling. Nat Cell Biol 4: 699-704.
-
(2002)
Nat Cell Biol
, vol.4
, pp. 699-704
-
-
Gao, X.1
Zhang, Y.2
Arrazola, P.3
Hino, O.4
Kobayashi, T.5
-
5
-
-
0037108750
-
Tuberous sclerosis complex-1 and -2 gene products function together to inhibit mammalian target of rapamycin (mTOR)-mediated downstream signaling
-
Tee AR, Fingar DC, Manning BD, Kwiatkowski DJ, Cantley LC, et al. (2002) Tuberous sclerosis complex-1 and-2 gene products function together to inhibit mammalian target of rapamycin (mTOR)-mediated downstream signaling. Proc Natl Acad Sci USA 99: 13571-13576.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 13571-13576
-
-
Tee, A.R.1
Fingar, D.C.2
Manning, B.D.3
Kwiatkowski, D.J.4
Cantley, L.C.5
-
6
-
-
0036713778
-
TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signalling
-
Inoki K, Li Y, Zhu T, Wu J, Guan KL, (2002) TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signalling. Nat Cell Biol 4: 648-657.
-
(2002)
Nat Cell Biol
, vol.4
, pp. 648-657
-
-
Inoki, K.1
Li, Y.2
Zhu, T.3
Wu, J.4
Guan, K.L.5
-
7
-
-
3342958797
-
The TSC1-2 tumor suppressor controls insulin-PI3K signaling via regulation of IRS proteins
-
Harrington LS, Findlay GM, Gray A, Tolkacheva T, Wigfield S, et al. (2004) The TSC1-2 tumor suppressor controls insulin-PI3K signaling via regulation of IRS proteins. J Cell Biol 166: 213-223.
-
(2004)
J Cell Biol
, vol.166
, pp. 213-223
-
-
Harrington, L.S.1
Findlay, G.M.2
Gray, A.3
Tolkacheva, T.4
Wigfield, S.5
-
8
-
-
4544343980
-
Inappropriate activation of the TSC/Rheb/mTOR/S6K cassette induces IRS1/2 depletion, insulin resistance, and cell survival deficiencies
-
Shah OJ, Wang Z, Hunter T, (2004) Inappropriate activation of the TSC/Rheb/mTOR/S6K cassette induces IRS1/2 depletion, insulin resistance, and cell survival deficiencies. Curr Biol 14: 1650-1656.
-
(2004)
Curr Biol
, vol.14
, pp. 1650-1656
-
-
Shah, O.J.1
Wang, Z.2
Hunter, T.3
-
9
-
-
0030696314
-
Molecular genetic and phenotypic analysis reveals differences between TSC1 and TSC2 associated familial and sporadic tuberous sclerosis
-
Jones AC, Daniells CE, Snell RG, Tachataki M, Idziaszczyk SA, et al. (1997) Molecular genetic and phenotypic analysis reveals differences between TSC1 and TSC2 associated familial and sporadic tuberous sclerosis. Hum Mol Genet 6: 2155-2161.
-
(1997)
Hum Mol Genet
, vol.6
, pp. 2155-2161
-
-
Jones, A.C.1
Daniells, C.E.2
Snell, R.G.3
Tachataki, M.4
Idziaszczyk, S.A.5
-
10
-
-
0035167932
-
Mutational analysis in a cohort of 224 tuberous sclerosis patients indicates increased severity of TSC2, compared with TSC1, disease in multiple organs
-
Dabora SL, Jozwiak S, Franz DN, Roberts PS, Nieto A, et al. (2001) Mutational analysis in a cohort of 224 tuberous sclerosis patients indicates increased severity of TSC2, compared with TSC1, disease in multiple organs. Am J Hum Genet 68: 64-80.
-
(2001)
Am J Hum Genet
, vol.68
, pp. 64-80
-
-
Dabora, S.L.1
Jozwiak, S.2
Franz, D.N.3
Roberts, P.S.4
Nieto, A.5
-
11
-
-
0043127125
-
Rheb GTPase is a direct target of TSC2 GAP activity and regulates mTOR signaling
-
Inoki K, Li Y, Xu T, Guan KL, (2003) Rheb GTPase is a direct target of TSC2 GAP activity and regulates mTOR signaling. Genes Dev. 17: 1829-1834.
-
(2003)
Genes Dev
, vol.17
, pp. 1829-1834
-
-
Inoki, K.1
Li, Y.2
Xu, T.3
Guan, K.L.4
-
12
-
-
0030064915
-
Presence of potent transcriptional activation domains in the predisposing tuberous sclerosis (Tsc2) gene product of the Eker rat model
-
Tsuchiya H, Orimoto K, Kobayashi T, Hino O, (1996) Presence of potent transcriptional activation domains in the predisposing tuberous sclerosis (Tsc2) gene product of the Eker rat model. Cancer Res 56: 429-433.
-
(1996)
Cancer Res
, vol.56
, pp. 429-433
-
-
Tsuchiya, H.1
Orimoto, K.2
Kobayashi, T.3
Hino, O.4
-
13
-
-
0032493629
-
Tuberous sclerosis gene 2 product modulates transcription mediated by steroid hormone receptor family members
-
Henry KW, Yuan X, Koszewski NJ, Onda H, Kwiatkowski DJ, et al. (1998) Tuberous sclerosis gene 2 product modulates transcription mediated by steroid hormone receptor family members. J Biol Chem 273: 20535-20539.
-
(1998)
J Biol Chem
, vol.273
, pp. 20535-20539
-
-
Henry, K.W.1
Yuan, X.2
Koszewski, N.J.3
Onda, H.4
Kwiatkowski, D.J.5
-
14
-
-
0032580368
-
A role of the tuberous sclerosis gene-2 product during neuronal differentiation
-
Soucek T, Hölzl G, Bernaschek G, Hengstschläger M, (1998) A role of the tuberous sclerosis gene-2 product during neuronal differentiation. Oncogene 16: 2197-2204.
-
(1998)
Oncogene
, vol.16
, pp. 2197-2204
-
-
Soucek, T.1
Hölzl, G.2
Bernaschek, G.3
Hengstschläger, M.4
-
15
-
-
0035019467
-
Tuberin-dependent membrane localization of polycystin-1: a functional link between polycystic kidney disease and the TSC2 tumor suppressor gene
-
Kleymenova E, Ibraghimov-Beskrovnaya O, Kugoh H, Everitt J, Xu H, et al. (2001) Tuberin-dependent membrane localization of polycystin-1: a functional link between polycystic kidney disease and the TSC2 tumor suppressor gene. Mol Cell 7: 823-832.
-
(2001)
Mol Cell
, vol.7
, pp. 823-832
-
-
Kleymenova, E.1
Ibraghimov-Beskrovnaya, O.2
Kugoh, H.3
Everitt, J.4
Xu, H.5
-
16
-
-
0042701991
-
Tuberous sclerosis complex gene products, Tuberin and Hamartin, control mTOR signaling by acting as a GTPase-activating protein complex toward Rheb
-
Tee AR, Manning BD, Roux PP, Cantley LC, Blenis J, (2003) Tuberous sclerosis complex gene products, Tuberin and Hamartin, control mTOR signaling by acting as a GTPase-activating protein complex toward Rheb. Curr Biol 13: 1259-1268.
-
(2003)
Curr Biol
, vol.13
, pp. 1259-1268
-
-
Tee, A.R.1
Manning, B.D.2
Roux, P.P.3
Cantley, L.C.4
Blenis, J.5
-
17
-
-
12744255189
-
Distinct effects of single amino-acid changes to tuberin on the function of the tuberin-hamartin complex
-
Nellist M, Sancak O, Goedbloed MA, Rohe C, van Netten D, et al. (2005) Distinct effects of single amino-acid changes to tuberin on the function of the tuberin-hamartin complex. Eur J Hum Genet 13: 59-68.
-
(2005)
Eur J Hum Genet
, vol.13
, pp. 59-68
-
-
Nellist, M.1
Sancak, O.2
Goedbloed, M.A.3
Rohe, C.4
van Netten, D.5
-
18
-
-
4444276510
-
Biochemical and functional characterizations of small GTPase Rheb and TSC2 GAP activity
-
Li Y, Inoki K, Guan KL, (2004) Biochemical and functional characterizations of small GTPase Rheb and TSC2 GAP activity. Mol Cell Biol 24: 7965-7975.
-
(2004)
Mol Cell Biol
, vol.24
, pp. 7965-7975
-
-
Li, Y.1
Inoki, K.2
Guan, K.L.3
-
19
-
-
21244477860
-
Aberrant beta-catenin signaling in tuberous sclerosis
-
Mak BC, Kenerson HL, Aicher LD, Barnes EA, Yeung RS, (2005) Aberrant beta-catenin signaling in tuberous sclerosis. Am J Patho 167: 107-116.
-
(2005)
Am J Patho
, vol.167
, pp. 107-116
-
-
Mak, B.C.1
Kenerson, H.L.2
Aicher, L.D.3
Barnes, E.A.4
Yeung, R.S.5
-
20
-
-
0033775869
-
The TSC1 tumour suppressor hamartin regulates cell adhesion through ERM proteins and the GTPase Rho
-
Lamb RF, Roy C, Diefenbach TJ, Vinters HV, Johnson MW, et al. (2000) The TSC1 tumour suppressor hamartin regulates cell adhesion through ERM proteins and the GTPase Rho. Nat Cell Biol 2: 281-287.
-
(2000)
Nat Cell Biol
, vol.2
, pp. 281-287
-
-
Lamb, R.F.1
Roy, C.2
Diefenbach, T.J.3
Vinters, H.V.4
Johnson, M.W.5
-
21
-
-
0037113967
-
The TSC1 tumor suppressor hamartin interacts with neurofilament-L and possibly functions as a novel integrator of the neuronal cytoskeleton
-
Haddad LA, Smith N, Bowser M, Niida Y, Murthy V, et al. (2002) The TSC1 tumor suppressor hamartin interacts with neurofilament-L and possibly functions as a novel integrator of the neuronal cytoskeleton. J Biol Chem 277: 44180-44186.
-
(2002)
J Biol Chem
, vol.277
, pp. 44180-44186
-
-
Haddad, L.A.1
Smith, N.2
Bowser, M.3
Niida, Y.4
Murthy, V.5
-
22
-
-
0037069690
-
Rho GTPases in cell biology
-
Etienne-Manneville S, Hall A, (2002) Rho GTPases in cell biology. Nature 420: 629-35.
-
(2002)
Nature
, vol.420
, pp. 629-635
-
-
Etienne-Manneville, S.1
Hall, A.2
-
23
-
-
42049092972
-
Regulation of actin assembly associated with protrusion and adhesion in cell migration
-
Le Clainche C, Carlier MF, (2008) Regulation of actin assembly associated with protrusion and adhesion in cell migration. Physiol Rev 88: 489-513.
-
(2008)
Physiol Rev
, vol.88
, pp. 489-513
-
-
Le Clainche, C.1
Carlier, M.F.2
-
24
-
-
79959677602
-
Life at the leading edge
-
Ridley AJ, (2011) Life at the leading edge. Cell 145: 1012-1022.
-
(2011)
Cell
, vol.145
, pp. 1012-1022
-
-
Ridley, A.J.1
-
25
-
-
3042822399
-
Plakins: goliaths that link cell junctions and the cytoskeleton
-
Jefferson JJ, Leung CL, Liem RK, (2004) Plakins: goliaths that link cell junctions and the cytoskeleton. Nat Rev Mol Cell Biol 5: 542-553.
-
(2004)
Nat Rev Mol Cell Biol
, vol.5
, pp. 542-553
-
-
Jefferson, J.J.1
Leung, C.L.2
Liem, R.K.3
-
26
-
-
33846847701
-
Rap1: a key regulator in cell-cell junction formation
-
Kooistra MR, Dubé N, Bos JL, (2007) Rap1: a key regulator in cell-cell junction formation. J Cell Sci 120: 17-22.
-
(2007)
J Cell Sci
, vol.120
, pp. 17-22
-
-
Kooistra, M.R.1
Dubé, N.2
Bos, J.L.3
-
27
-
-
50249107474
-
Paxillin comes of age
-
Deakin NO, Turner CE, (2008) Paxillin comes of age. J Cell Sci 121: 2435-2444.
-
(2008)
J Cell Sci
, vol.121
, pp. 2435-2444
-
-
Deakin, N.O.1
Turner, C.E.2
-
28
-
-
76349098227
-
Rho signaling and tight junction functions
-
Terry S, Nie M, Matter K, Balda MS, (2010) Rho signaling and tight junction functions. Physiology 25: 16-26.
-
(2010)
Physiology
, vol.25
, pp. 16-26
-
-
Terry, S.1
Nie, M.2
Matter, K.3
Balda, M.S.4
-
29
-
-
11244277987
-
TSC2 modulates actin cytoskeleton and focal adhesion through TSC1-binding domain and the Rac1 GTPase
-
Goncharova E, Goncharov D, Noonan D, Krymskaya VP, (2004) TSC2 modulates actin cytoskeleton and focal adhesion through TSC1-binding domain and the Rac1 GTPase. J Cell Biol 167: 1171-82.
-
(2004)
J Cell Biol
, vol.167
, pp. 1171-1182
-
-
Goncharova, E.1
Goncharov, D.2
Noonan, D.3
Krymskaya, V.P.4
-
30
-
-
17844369428
-
The tuberous sclerosis-1 (TSC1) gene product hamartin suppresses cell growth and augments the expression of the TSC2 product tuberin by inhibiting its ubiquitination
-
Benvenuto G, Li S, Brown SJ, Braverman R, Vass WC, et al. (2000) The tuberous sclerosis-1 (TSC1) gene product hamartin suppresses cell growth and augments the expression of the TSC2 product tuberin by inhibiting its ubiquitination. Oncogene 19: 6306-6316.
-
(2000)
Oncogene
, vol.19
, pp. 6306-6316
-
-
Benvenuto, G.1
Li, S.2
Brown, S.J.3
Braverman, R.4
Vass, W.C.5
-
31
-
-
33646854721
-
TSC1 stabilizes TSC2 by inhibiting the interaction between TSC2 and the HERC1 ubiquitin ligase
-
Chong-Kopera H, Inoki K, Li Y, Zhu T, Garcia-Gonzalo FR, et al. (2006) TSC1 stabilizes TSC2 by inhibiting the interaction between TSC2 and the HERC1 ubiquitin ligase. J Biol Chem 281: 8313-8316.
-
(2006)
J Biol Chem
, vol.281
, pp. 8313-8316
-
-
Chong-Kopera, H.1
Inoki, K.2
Li, Y.3
Zhu, T.4
Garcia-Gonzalo, F.R.5
-
32
-
-
0036501277
-
A mouse model of TSC1 reveals sex-dependent lethality from liver hemangiomas, and up-regulation of p70S6 kinase activity in Tsc1 null cells
-
Kwiatkowski DJ, Zhang H, Bandura JL, Heiberger KM, Glogauer M, et al. (2002) A mouse model of TSC1 reveals sex-dependent lethality from liver hemangiomas, and up-regulation of p70S6 kinase activity in Tsc1 null cells. Hum Mol Genet 11: 525-534.
-
(2002)
Hum Mol Genet
, vol.11
, pp. 525-534
-
-
Kwiatkowski, D.J.1
Zhang, H.2
Bandura, J.L.3
Heiberger, K.M.4
Glogauer, M.5
-
33
-
-
0029814436
-
Suppression of tumorigenicity by the wild-type tuberous sclerosis 2 (Tsc2) gene and its C-terminal region
-
Jin F, Wienecke R, Xiao GH, Maize JC Jr, DeClue JE, et al. (1996) Suppression of tumorigenicity by the wild-type tuberous sclerosis 2 (Tsc2) gene and its C-terminal region. Proc Natl Acad Sci USA 93: 9154-9159.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 9154-9159
-
-
Jin, F.1
Wienecke, R.2
Xiao, G.H.3
Maize Jr., J.C.4
DeClue, J.E.5
-
34
-
-
0030044323
-
Suppression of the neoplastic phenotype by replacement of the Tsc2 gene in Eker rat renal carcinoma cells
-
Orimoto K, Tsuchiya H, Kobayashi T, Matsuda T, Hino O, (1996) Suppression of the neoplastic phenotype by replacement of the Tsc2 gene in Eker rat renal carcinoma cells. Biochem Biophys Res Commun 219: 70-75.
-
(1996)
Biochem Biophys Res Commun
, vol.219
, pp. 70-75
-
-
Orimoto, K.1
Tsuchiya, H.2
Kobayashi, T.3
Matsuda, T.4
Hino, O.5
-
35
-
-
0033861013
-
The TSC1 gene product, hamartin, negatively regulates cell proliferation
-
Miloloza A, Rosner M, Nellist M, Halley D, Bernaschek G, et al. (2000) The TSC1 gene product, hamartin, negatively regulates cell proliferation. Hum Mol Genet 9: 1721-1727.
-
(2000)
Hum Mol Genet
, vol.9
, pp. 1721-1727
-
-
Miloloza, A.1
Rosner, M.2
Nellist, M.3
Halley, D.4
Bernaschek, G.5
-
36
-
-
39849100440
-
Adherens and tight junctions: structure, function and connections to the actin cytoskeleton
-
Hartsock A, Nelson WJ, (2008) Adherens and tight junctions: structure, function and connections to the actin cytoskeleton. Biochim Biophys Acta 1778: 660-669.
-
(2008)
Biochim Biophys Acta
, vol.1778
, pp. 660-669
-
-
Hartsock, A.1
Nelson, W.J.2
-
37
-
-
33646023695
-
Prolonged rapamycin treatment inhibits mTORC2 assembly and Akt/PKB
-
Sarbassov DD, Ali SM, Sengupta S, Sheen JH, Hsu PP, et al. (2006) Prolonged rapamycin treatment inhibits mTORC2 assembly and Akt/PKB. Mol Cell 22: 159-168.
-
(2006)
Mol Cell
, vol.22
, pp. 159-168
-
-
Sarbassov, D.D.1
Ali, S.M.2
Sengupta, S.3
Sheen, J.H.4
Hsu, P.P.5
-
38
-
-
34147146014
-
Rapamycin derivatives reduce mTORC2 signaling and inhibit AKT activation in AML
-
Zeng Z, Sarbassov dos D, Samudio IJ, Yee KW, Munsell MF, et al. (2007) Rapamycin derivatives reduce mTORC2 signaling and inhibit AKT activation in AML. Blood 109: 3509-3512.
-
(2007)
Blood
, vol.109
, pp. 3509-3512
-
-
Zeng, Z.1
dos Sarbassov, D.2
Samudio, I.J.3
Yee, K.W.4
Munsell, M.F.5
-
39
-
-
0035902509
-
A germ-line Tsc1 mutation causes tumor development and embryonic lethality that are similar, but not identical to, those caused by Tsc2 mutation in mice
-
Kobayashi T, Minowa O, Sugitani Y, Takai S, Mitani H, et al. (2001) A germ-line Tsc1 mutation causes tumor development and embryonic lethality that are similar, but not identical to, those caused by Tsc2 mutation in mice. Proc Natl Acad Sci USA 98: 8762-8767.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 8762-8767
-
-
Kobayashi, T.1
Minowa, O.2
Sugitani, Y.3
Takai, S.4
Mitani, H.5
-
40
-
-
0035805162
-
Drosophila Tsc1 functions with Tsc2 to antagonize insulin signaling in regulating cell growth, cell proliferation, and organ size
-
Potter CJ, Huang H, Xu T, (2001) Drosophila Tsc1 functions with Tsc2 to antagonize insulin signaling in regulating cell growth, cell proliferation, and organ size. Cell 105: 357-368.
-
(2001)
Cell
, vol.105
, pp. 357-368
-
-
Potter, C.J.1
Huang, H.2
Xu, T.3
-
41
-
-
0037028305
-
Tuberin, the tuberous sclerosis complex 2 tumor suppressor gene product, regulates Rho activation, cell adhesion and migration
-
Astrinidis A, Cash TP, Hunter DS, Walker CL, Chernoff J, et al. (2002) Tuberin, the tuberous sclerosis complex 2 tumor suppressor gene product, regulates Rho activation, cell adhesion and migration. Oncogene 21: 8470-8476.
-
(2002)
Oncogene
, vol.21
, pp. 8470-8476
-
-
Astrinidis, A.1
Cash, T.P.2
Hunter, D.S.3
Walker, C.L.4
Chernoff, J.5
-
42
-
-
77955296990
-
Tuberous sclerosis complex 2 (TSC2) regulates cell migration and polarity through activation of CDC42 and RAC1
-
Larson Y, Liu J, Stevens PD, Li X, Li J, et al. (2010) Tuberous sclerosis complex 2 (TSC2) regulates cell migration and polarity through activation of CDC42 and RAC1. J Biol Chem 285: 24987-24998.
-
(2010)
J Biol Chem
, vol.285
, pp. 24987-24998
-
-
Larson, Y.1
Liu, J.2
Stevens, P.D.3
Li, X.4
Li, J.5
-
43
-
-
80051495791
-
Tsc1 mutant neural stem/progenitor cells exhibit migration deficits and give rise to subependymal lesions in the lateral ventricle
-
Zhou J, Shrikhande G, Xu J, McKay RM, Burns DK, et al. (2011) Tsc1 mutant neural stem/progenitor cells exhibit migration deficits and give rise to subependymal lesions in the lateral ventricle. Genes Dev 25: 1595-1600.
-
(2011)
Genes Dev
, vol.25
, pp. 1595-1600
-
-
Zhou, J.1
Shrikhande, G.2
Xu, J.3
McKay, R.M.4
Burns, D.K.5
-
44
-
-
0033594123
-
Rho GTPases control polarity, protrusion, and adhesion during cell movement
-
Nobes CD, Hall A, (1999) Rho GTPases control polarity, protrusion, and adhesion during cell movement. J Cell Biol 144: 1235-1244.
-
(1999)
J Cell Biol
, vol.144
, pp. 1235-1244
-
-
Nobes, C.D.1
Hall, A.2
-
45
-
-
0028821093
-
Cell-to-cell adherens junction formation and actin filament organization: similarities and differences between non-polarized fibroblasts and polarized epithelial cells
-
Yonemura S, Itoh M, Nagafuchi A, Tsukita S, (1995) Cell-to-cell adherens junction formation and actin filament organization: similarities and differences between non-polarized fibroblasts and polarized epithelial cells. J Cell Sci 108: 127-142.
-
(1995)
J Cell Sci
, vol.108
, pp. 127-142
-
-
Yonemura, S.1
Itoh, M.2
Nagafuchi, A.3
Tsukita, S.4
-
46
-
-
0036746704
-
Actin cable dynamics and Rho/Rock orchestrate a polarized cytoskeletal architecture in the early steps of assembling a stratified epithelium
-
Vaezi A, Bauer C, Vasioukhin V, Fuchs E, (2002) Actin cable dynamics and Rho/Rock orchestrate a polarized cytoskeletal architecture in the early steps of assembling a stratified epithelium. Dev Cell 3: 367-381.
-
(2002)
Dev Cell
, vol.3
, pp. 367-381
-
-
Vaezi, A.1
Bauer, C.2
Vasioukhin, V.3
Fuchs, E.4
-
47
-
-
29244449302
-
Shroom regulates epithelial cell shape via the apical positioning of an actomyosin network
-
Hildebrand JD, (2005) Shroom regulates epithelial cell shape via the apical positioning of an actomyosin network. J Cell Sci 118: 5191-5203.
-
(2005)
J Cell Sci
, vol.118
, pp. 5191-5203
-
-
Hildebrand, J.D.1
-
48
-
-
38349138921
-
EPLIN mediates linkage of the cadherin catenin complex to F-actin and stabilizes the circumferential actin belt
-
Abe K, Takeichi M, (2008) EPLIN mediates linkage of the cadherin catenin complex to F-actin and stabilizes the circumferential actin belt. Proc Natl Acad Sci USA 105: 3-19.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 3-19
-
-
Abe, K.1
Takeichi, M.2
-
49
-
-
77951919561
-
Adherens junctions connect stress fibres between adjacent endothelial cells
-
Millán J, Cain RJ, Reglero-Real N, Bigarella C, Marcos-Ramiro B, et al. (2010) Adherens junctions connect stress fibres between adjacent endothelial cells. BMC Biol 8: 11.
-
(2010)
BMC Biol
, vol.8
, pp. 11
-
-
Millán, J.1
Cain, R.J.2
Reglero-Real, N.3
Bigarella, C.4
Marcos-Ramiro, B.5
-
50
-
-
44949215822
-
The TSC1-TSC2 complex is required for proper activation of mTOR complex 2
-
Huang J, Dibble CC, Matsuzaki M, Manning BD, (2008) The TSC1-TSC2 complex is required for proper activation of mTOR complex 2. Mol Cell Biol 8: 4104-1415.
-
(2008)
Mol Cell Biol
, vol.8
, pp. 1415-4104
-
-
Huang, J.1
Dibble, C.C.2
Matsuzaki, M.3
Manning, B.D.4
-
51
-
-
68049126433
-
Signaling events downstream of mammalian target of rapamycin complex 2 are attenuated in cells and tumors deficient for the tuberous sclerosis complex tumor suppressors
-
Huang J, Wu S, Wu CL, Manning BD, (2009) Signaling events downstream of mammalian target of rapamycin complex 2 are attenuated in cells and tumors deficient for the tuberous sclerosis complex tumor suppressors. Cancer Res 69: 6107-6114.
-
(2009)
Cancer Res
, vol.69
, pp. 6107-6114
-
-
Huang, J.1
Wu, S.2
Wu, C.L.3
Manning, B.D.4
-
52
-
-
81055130119
-
Balanced Rac1 and RhoA activities regulate cell shape and drive invagination morphogenesis in epithelia
-
Chauhan BK, Lou M, Zheng Y, Lang RA, (2011) Balanced Rac1 and RhoA activities regulate cell shape and drive invagination morphogenesis in epithelia. Proc Natl Acad Sci USA 108: 18289-94.
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, pp. 18289-18294
-
-
Chauhan, B.K.1
Lou, M.2
Zheng, Y.3
Lang, R.A.4
-
53
-
-
0033558236
-
Isolation and characterization of a rat homologue of the human tuberous sclerosis 1 gene (Tsc1) and analysis of its mutations in rat renal carcinomas
-
Satake N, Kobayashi T, Kobayashi E, Izumi K, Hino O, (1999) Isolation and characterization of a rat homologue of the human tuberous sclerosis 1 gene (Tsc1) and analysis of its mutations in rat renal carcinomas. Cancer Res 59: 849-855.
-
(1999)
Cancer Res
, vol.59
, pp. 849-855
-
-
Satake, N.1
Kobayashi, T.2
Kobayashi, E.3
Izumi, K.4
Hino, O.5
-
54
-
-
56149090835
-
The G1556S-type tuberin variant suppresses tumor formation in tuberous sclerosis 2 mutant (Eker) rats despite its deficiency in mTOR inhibition
-
Shiono M, Kobayashi T, Takahashi R, Sun G, Abe M, et al. (2008) The G1556S-type tuberin variant suppresses tumor formation in tuberous sclerosis 2 mutant (Eker) rats despite its deficiency in mTOR inhibition. Oncogene 27: 6690-6697.
-
(2008)
Oncogene
, vol.27
, pp. 6690-6697
-
-
Shiono, M.1
Kobayashi, T.2
Takahashi, R.3
Sun, G.4
Abe, M.5
-
55
-
-
0034667869
-
A new Western blotting method using polymer immunocomplexes: detection of Tsc1 and Tsc2 expression in various cultured cell lines
-
Fukuda T, Tani Y, Kobayashi T, Hirayama Y, Hino O, (2000) A new Western blotting method using polymer immunocomplexes: detection of Tsc1 and Tsc2 expression in various cultured cell lines. Anal Biochem 285: 274-276.
-
(2000)
Anal Biochem
, vol.285
, pp. 274-276
-
-
Fukuda, T.1
Tani, Y.2
Kobayashi, T.3
Hirayama, Y.4
Hino, O.5
|