A genetically encoded fluorescent sensor of ERK activity

Proceedings of the National Academy of Sciences of the United States of America

Volumn 105, Issue 49, 2008, Pages 19264-19269

  Harvey, Christopher D ^a,b   Ehrhardt, Anka G ^c   Cellurale, Cristina ^c   Zhong, Haining ^a   Yasuda, Ryohei ^d   Davis, Roger J ^c   Svoboda, Karel ^a,b  

^a HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^b Howard Hughes Medical Institute Cold Spring Harbor Laboratory Cold Spring Harbor   (United States)

^c UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

^d DUKE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Fluorescence lifetime imaging microscopy; FRET; MAPK

Indexed keywords

EPIDERMAL GROWTH FACTOR; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; STRESS ACTIVATED PROTEIN KINASE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL STIMULATION; CONTROLLED STUDY; DENDRITE; ENZYME ACTIVITY; EXTRACELLULAR SIGNAL REGULATED KINASE REPORTER; FLUORESCENCE RESONANCE ENERGY TRANSFER; HIPPOCAMPUS; HUMAN; HUMAN CELL; NONHUMAN; PRIORITY JOURNAL; PYRAMIDAL NERVE CELL; RAT; REPORTER GENE; SENSOR; SIGNAL NOISE RATIO; SIGNAL TRANSDUCTION;

ACTION POTENTIALS; ANIMALS; ARTIFACTS; BACTERIAL PROTEINS; CELL LINE; DENDRITES; ENDOTHELIAL CELLS; ENZYME ACTIVATION; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FLUORESCENCE RESONANCE ENERGY TRANSFER; FLUORESCENT DYES; GENES, REPORTER; GREEN FLUORESCENT PROTEINS; HIPPOCAMPUS; HUMANS; KIDNEY; LUMINESCENT PROTEINS; MAP KINASE SIGNALING SYSTEM; ORGAN CULTURE TECHNIQUES; PATCH-CLAMP TECHNIQUES; PYRAMIDAL CELLS; RATS;

EID: 58049221116     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0804598105     Document Type: Article

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