Role of omega-3 fatty acids in cardiovascular disease prevention;Papel de los ácidos grasos omega-3 en la prevención de enfermedades cardiovasculares

Nutricion Hospitalaria

Volumn 28, Issue 1, 2013, Pages 1-5

  Piñeiro Corrales, Guadalupe ^a   Lago Rivero, N ^a   Culebras Fernández, Jesús M ^b  

^a UNIVERSITY OF VIGO   (Spain)

^b Gerencia Regional de Salud de Castilla y León   (Spain)

Author keywords

Cardiovascular disease; Omega 3; Polyunsaturated fatty acids

Indexed keywords

DOCOSAHEXAENOIC ACID; ICOSAPENTAENOIC ACID; OMEGA 3 FATTY ACID;

ANIMAL; CARDIOVASCULAR DISEASES; DEATH, SUDDEN, CARDIAC; DIET; FISH; HUMAN; METABOLISM; MORTALITY; CARDIOVASCULAR DISEASE; REVIEW; SUDDEN CARDIAC DEATH;

ANIMALS; CARDIOVASCULAR DISEASES; DEATH, SUDDEN, CARDIAC; DIET; DOCOSAHEXAENOIC ACIDS; EICOSAPENTAENOIC ACID; FATTY ACIDS, OMEGA-3; FISHES; HUMANS;

EID: 84872790479     PISSN: 02121611     EISSN: 16995198     Source Type: Journal    
DOI: 10.3305/nh.2013.28.1.6312     Document Type: Review

References (59)

1. Jiménez Jiménez FJ, Cervera Montes M, Blesa Malpica AL; Metabolism and Nutrition Working Group of the Spanish Society of Intensive Care Medicine and Coronary units. Guidelines for specialized nutritional and metabolic support in the critically-ill patient: update. Consensus SEMICYUC-SENPE: cardiac patient. Nutr Hosp 2011; 26 (Suppl. 2): 76-80.
2. Mori TA, Beilin LJ, Burke V, Morris J, Ritchie J. Interactions between dietary fat, fish, and fish oils and their effects on platelet function in men at risk of cardiovascular disease. Arterioscler Thromb Vasc Biol 1997; 17: 279-286.
3. Harris WS, Pottala JV, Sands SA, Jones PG. Comparison of the effects of fish and fish-oil capsules on the n-3 fatty acid content of blood cells and plasma phospholipids. Am J Clin Nutr 2007; 86: 1621-1625.
4. Metcalf, RG James MJ, Gibson RA, et al. Effects of fish-oil supplementation on myocardial fatty acids in humans. Am J Clin Nutr 2007; 85: 1222-1228.
5. Reed CF. Phospholipid exchange between plasma and erythrocytes in man and the dog. J Clin Invest 1968; 47: 749-760.
6. Park Y, Harris WS. EPA but not DHA, decrease mean platlet volume in normal subjects. Lipids 2002; 37: 941-946.
7. Park Y, Harris WS. Omega -3 fatty acid supplementation accelerates chylomicron triglyceride clearance. J Lip Res 2003; 44: 455-463.
8. Luostarinen R, Boberg M, Saldeen T. Fatty acid composition in total phospholipids of human coronary arteries in sudden cardiac death. Atherosclerosis 1993; 99: 187-193.
9. Hallgren CG, Hallmans G, Jansson JH, et al. Markers of high fish intake are associated with decreased risk of a first myocardial infarction. Br J Nutr 2001; 86: 397-404.
10. Erkkila AT, Lehto S, Pyorala K et al. N-3 fatty acids and 5-y risks of death and cardiovascular disease events in patients with coronary artery disease. Am J Clin Nutr 2003; 78: 65-71.
11. Rissanen T, Voutilainen S, Nyyssönen K et al. Fish oil-derived fatty acids, docosahexaenoic acid and docosapentaenoic acid, and the risk of acute coronary events. The Kuopio Ischaemic Heart Disease Risk Factor study. Circulation 2000; 102: 2677-2679.
12. He K, Song Y, Daviglus ML, Liu K, Van Horn L, Dyer AR et al. Accumulated evidence on fish consumption and coronary heart disease mortality: a meta-analysis of cohort studies. Circulation 2004; 109: 2705-2711.
13. Parks JS, Gebre AK. Studies on the effect of dietary fish oil on the physical and chemical properties of low density lipoproteins in cynomolgus monkeys. J Lipid Res 1991; 32: 305-315.
14. Gebauer SK, Psota TL, Harris WS, Kris-Etherton PM. N-3 Fatty acid dietary recommendations and food sources to achieve essentiality and cardiovascular benefits. Am J Clin Nutr 2006; 83: S1526-1535S.
15. Jump D. Fatty acid regulation of gene transcription. Crit Rev Clin Lab Sci 2004; 41: 41-78.
16. von Schacky C, Angerer P, Kothny W et al. The effect of dietary n-3 fatty acids on coronary atherosclerosis. A randomized, double-blind, placebo-controlled trial. Ann Intern Med 1999; 130: 554-562.
17. Neuringer M, Anderson GJ, Connor WE. The essentiality of n-3 fatty acids for the development and function of the retina and brain. Annu Rev Nutr 1988; 8: 517-541.
18. Soderberg M, Edlund C, Kristensson K, Dallner G. Fatty acid composition of brain phospholipids in aging and in Alzheimer's disease. Lipids 1991; 26: 421-425.
19. De Lorgeril M, Salen P, Martin JL, Monjaud I, Delaye J, Mamelle N. Mediterranean diet, traditional risk factors, and the rate of cardiovascular complications after myocardial infarction: final report of the Lyon Diet Heart Study. Circulation 1999; 99: 779-785.
20. Burr ML, Fehily AM, Gilbert JF et al. Effects of changes in fat, fish, and fibre intakes on death and myocardial reinfarction: diet and reinfarction trial (DART). Lancet 1989; 2: 757-761.
21. GISSI-Prevenzione Investigators. Dietary supplementation with n-3 polyunsaturated fatty acids and vitamin E in 11,324 patients with myocardial infarction: results of the GISSI-Prevenzione trial. Lancet 1999; 354: 447-455.
22. Rissanen T, Voutilainen S, Nyyssönen K et al. Fish oil-derived fatty acids, docosahexaenoic acid and docosapentaenoic acid, and the risk of acute coronary events. The Kuopio Ischaemic Heart Disease Risk Factor study. Circulation 2000; 102: 2677-2679.
23. Harris WS. Omega-3 fatty acids and cardiovascular disease: A case for omega-3 index as a new risk factor. Pharmacological Research 2007; 55: 217-223.
24. Mozaffarian D. Fish and n-3 fatty acids for the prevention of fatal coronary heart disease and sudden cardiac death. American Journal of Clinical Nutrition 2008; (87) 6: 1991S-1996S.
25. Daviglus ML, Stamler J, Orencia AJ et al. Fish consumption and the 30-year risk of fatal myocardial infarction. N Engl J Med 1997; 336:1046-1053.
26. Kromhout D, Feskens EJ, Bowles CH. The protective effect of a small amount of fish on coronary heart disease mortality in an elderly population. Int J Epidemiol 1995; 24: 340-345.
27. Siscovick DS, Raghunathan TE, King I et al. Dietary intake and cell membrane levels of long-chain n-3 polyunsaturated fatty acids and the risk of primary cardiac arrest. JAMA 1995; 274: 1363-1367.
28. Oomen CM, Feskens EJ, Rasanen L et al. Fish consumption and coronary heart disease mortality in Finland, Italy, and The Netherlands. Am J Epidemiol 2000; 151: 999-1006.
29. Yuan JM, Ross RK, Gao YT, Yu MC. Fish and shellfish consumption in relation to death from myocardial infarction among men in Shanghai, China. Am J Epidemiol 2001; 154: 809-816.
30. Hu FB, Bronner L, Willett WC et al. Fish and omega-3 fatty acid intake and risk of coronary heart disease in women. JAMA 2002; 287: 1815-1821.
31. Lemaitre RN, King IB, Mozaffarian D, Kuller LH, Tracy RP, Siscovick DS. N-3 Polyunsaturated fatty acids, fatal ischemic heart disease, and nonfatal myocardial infarction in older adults: the Cardiovascular Health Study. Am J Clin Nutr 2003; 77: 319-325.
32. Fraser GE, Sabate J, Beeson WL, Strahan TM. A possible protective effect of nut consumption on risk of coronary heart disease: the Adventist Health Study. Arch Intern Med 1992; 152: 1416-1424.
33. Mann JI, Appleby PN, Key TJ, Thorogood M. Dietary determinants of ischaemic heart disease in health conscious individuals. Heart 1997; 78: 450-455.
34. Osler M, Andreasen AH, Hoidrup S. No inverse association between fish consumption and risk of death from all-causes, and incidence of coronary heart disease in middle-aged, Danish adults. J Clin Epidemiol 2003; 56: 274-279.
35. Folsom AR, Demissie Z. Fish intake, marine omega-3 fatty acids, and mortality in a cohort of postmenopausal women. Am J Epidemiol 2004; 160: 1005-1010.
36. Nakamura Y, Ueshima H, Okamura T et al. Association between fish consumption and all-cause and cause-specific mortality in Japan: NIPPON DATA80, 1980-99. Am J Med 2005; 118: 239-245.
37. Siscovick DS, Lemaitre RN, Mozaffarian D. The fish story: a diet-heart hypothesis with clinical implications: n-3 polyunsaturated fatty acids, myocardial vulnerability, and sudden death. Circulation 2003; 107: 2632-2634.
38. Burr ML, Ashfield-Watt PA, Dunstan FD et al. Lack of benefit of dietary advice to men with angina: results of a controlled trial. Eur J Clin Nutr 2003; 57: 193-200.
39. Durrleman S, Simon R. Flexible regression models with cubic splines. Stat Med 1989; 8: 551-561.
40. Smith PL. Splines as a useful and convenient statistical tool. Am Stat 1979; 33: 57-62.
41. Burr ML, Fehily AM, Gilbert JF et al. Effects of changes in fat, fish, and fibre intakes on death and myocardial reinfarction: diet and reinfarction trial (DART). Lancet 1989; 2: 757-761.
42. Chiuve SE, Rimm EB, Sandhu RK, Bernstein AM, Rexrode KM, Manson JE, Willett WC, Albert CM. Dietary fat quality and risk of sudden cardiac death in women. Am J Clin Nutr 2012; 96 (3): 498-507.
43. He K, Song Y, Daviglus ML, Liu K, Van Horn L, Dyer AR et al. Accumulated evidence on fish consumption and coronary heart disease mortality: a meta-analysis of cohort studies. Circulation 2004; 109: 2705-2711.
44. Sekikawa A, Curb JD, Ueshima H, El-Saed A, Kadowaki T et al. Marine-derived n-3 fatty acids and atherosclerosis in Japanese, Japanese-American, and white men: a cross-sectional study. J Am Coll Cardiol 2008; 52 (6): 417-424.
45. Calder PC. The role of marine omega-3 (n-3) fatty acids in inflammatory processes, atherosclerosis and plaque stability. Mol Nutr Food Res 2012; 56 (7): 1073-1080.
46. Nozue T, Yamamoto S, Tohyama S, Fukui K, Umezawa S, Onishi Y, Kunishima T et al. Effects of Serum n-3 to n-6 Polyunsaturated Fatty Acids Ratios on Coronary Atherosclerosis in Statin-Treated Patients With Coronary Artery Disease. Am J Cardiol 2012; Oct 2. pii: S0002-9149(12)02055-3. doi: 10.1016/j.amjcard.2012.08.038.
47. Welch AA, Bingham SA, Ive J, Friesen MD, Wareham NJ, Riboli E and Khaw KT. Dietary fish intake and plasma phospholipid n-3 polyunsaturated fatty acid concentrations in men and women in the European Prospective Investigation into Cancer-Norfolk United Kingdom cohort. Am J Clin Nutr 2006; 84 (6): 1330-1339.
48. Whelan J, Rust C. Innovative dietary sources of n-3 fatty acids. Annu Rev Nutr 2006; 26: 75-103.
49. Burdge G. Alpha-linolenic acid metabolism in men and women: nutritional and biological implications. Curr Opin Clin Nutr Metab Care 2004; 7: 137-144.
50. Mozaffarian D, Ascherio A, Hu FB, Stampfer MJ, Willett WC, Siscovick DS, Rimm EB. Interplay between different polyunsaturated fatty acids and risk of coronary heart disease in men. Circulation 2005; 111: 157-164.
51. Mozaffarian D. Does alpha-linolenic acid intake reduce the risk of coronary heart disease? A review of the evidence [review]. Altern Ther Health Med 2005; 11: 24-30; quiz 31, 79.
52. Albert CM, Oh K, Whang W, Manson JE, Chae CU, Stampfer MJ, Willett WC, Hu FB. Dietary alpha-linolenic acid intake and risk of sudden cardiac death and coronary heart disease. Circulation 2005; 112: 3232-3238.
53. London B, Albert C, Anderson ME et al. Omega-3 Fatty Acids and Cardiac Arrhythmias: Prior Studies and Recommendations for Future Research.A Report from the National Heart, Lung, and Blood Institute and Office of Dietary Supplements Omega-3 Fatty Acids and Their Role in Cardiac Arrhythmogenesis. Workshop Circulation 2007; 116: 320-335.
54. Guallar E, Aro A, Jiménez FJ, Martín-Moreno JM, Salminen I, Van't Veer P et al. Omega-3 fatty acids in adipose tissue and risk of myocardial infarction: the EURAMIC Study. Arterioscler Thromb Vasc Biol 1999; 19: 1111-1118.
55. Hu FB, Stampfer MJ, Manson JE, Rimm EB, Wolk A, Colditz GA et al. Dietary intake of linolenic acid and risk of fatal ischemic heart disease among women. Am J Clin Nutr 1999; 69: 890-897.
56. Pan A, Chen M, Chowdhury R, Wu JH, Sun Q, Campos H, Mozaffarian D, Hu FB. α-Linolenic acid and risk of cardiovascular disease: a systematic review and meta-analysis. Am J Clin Nutr 2012; doi: 10.3945/ajcn.112.044040.
57. Djousse L, Rautaharju PM, Hopkins PN, Whitsel EA, Arnett DK, Eckfeldt JH et al; Investigators of the NHLBI Family Heart Study. Dietary linolenic acid and adjusted QT and JT intervals in the National Heart, Lung, and Blood Institute Family Heart study. J Am Coll Cardiol 2005; 45: 1716-1722.
58. Christensen JH. N-3 fatty acids and the risk of sudden cardiac death. Emphasis on heart rate variability. Dan Med Bull 2003; 50: 347-367.
59. Mozaffarian D, Rimm EB. Fish intake, contaminants, and human health: evaluating the risks and the benefits. JAMA 2006; 296: 1885-1899.