-
1
-
-
21044443182
-
Diabetic vascular complications: Pathophysiology, biochemical basis and potential therapeutic strategy
-
Yamagishi S, Imaizumi T. Diabetic vascular complications: Pathophysiology, biochemical basis and potential therapeutic strategy. Curr Pharm Des 2005;11:2279-2299.
-
(2005)
Curr Pharm des
, vol.11
, pp. 2279-2299
-
-
Yamagishi, S.1
Imaizumi, T.2
-
2
-
-
0035856980
-
Biochemistry and molecular cell biology of diabetic complications
-
Brownlee M. Biochemistry and molecular cell biology of diabetic complications. Nature 2001;414:813-820.
-
(2001)
Nature
, vol.414
, pp. 813-820
-
-
Brownlee, M.1
-
3
-
-
0025945553
-
Formation of pentosidine during nonenzymatic browning of proteins by glucose. Identification of glucose and other carbohydrates as possible precursors of pentosidine in vivo
-
Dyer DG, Blackledge JA, Thorpe SR, Baynes JW. Formation of pentosidine during nonenzymatic browning of proteins by glucose. Identification of glucose and other carbohydrates as possible precursors of pentosidine in vivo. J Biol Chem 1991;266:11654-11660.
-
(1991)
J Biol Chem
, vol.266
, pp. 11654-11660
-
-
Dyer, D.G.1
Blackledge, J.A.2
Thorpe, S.R.3
Baynes, J.W.4
-
4
-
-
0025948114
-
Mechanism of formation of the Maillard protein cross-link pentosidine. Glucose, fructose, and ascorbate as pentosidine precursors
-
Grandhee SK, Monnier VM. Mechanism of formation of the Maillard protein cross-link pentosidine. Glucose, fructose, and ascorbate as pentosidine precursors. J Biol Chem 1991;266:11649-11653.
-
(1991)
J Biol Chem
, vol.266
, pp. 11649-11653
-
-
Grandhee, S.K.1
Monnier, V.M.2
-
5
-
-
0028934990
-
Mechanism of protein modification by glyoxal and glycoaldehyde, reactive intermediates of the Maillard reaction
-
Glomb MA, Monnier VM. Mechanism of protein modification by glyoxal and glycoaldehyde, reactive intermediates of the Maillard reaction. J Biol Chem 1995;70:10017-10026.
-
(1995)
J Biol Chem
, vol.70
, pp. 10017-10026
-
-
Glomb, M.A.1
Monnier, V.M.2
-
6
-
-
0026482265
-
Advanced glycosylation: Chemistry, biology, and implications for diabetes and aging
-
Bucala, Cerami A. Advanced glycosylation: Chemistry, biology, and implications for diabetes and aging. Adv Pharmacol 1992; 23:1-34.
-
(1992)
Adv Pharmacol
, vol.23
, pp. 1-34
-
-
Bucala Cerami, A.1
-
7
-
-
0142029114
-
Novel inhibitors of advanced glycation endproducts
-
Rahbar S, Figarola JL. Novel inhibitors of advanced glycation endproducts. Arch Biochem Biophys 2003;419:63-79.
-
(2003)
Arch Biochem Biophys
, vol.419
, pp. 63-79
-
-
Rahbar, S.1
Figarola, J.L.2
-
8
-
-
0036167208
-
Diabetes and advanced glycation endproducts
-
Vlassara H, Palace MR. Diabetes and advanced glycation endproducts. J Intern Med 2002;251:87-101.
-
(2002)
J Intern Med
, vol.251
, pp. 87-101
-
-
Vlassara, H.1
Palace, M.R.2
-
9
-
-
0032029363
-
AGEs and their interaction with AGE-receptors in vascular disease and diabetes mellitus I. The AGE concept
-
Bierhaus A, Hofmann MA, Ziegler R, Nawroth PP. AGEs and their interaction with AGE-receptors in vascular disease and diabetes mellitus. I. The AGE concept. Cardiovasc Res 1998;37:586-600.
-
(1998)
Cardiovasc Res
, pp. 37586-37600
-
-
Bierhaus, A.1
Hofmann, M.A.2
Ziegler, R.3
Nawroth, P.P.4
-
10
-
-
0034277471
-
Atherosclerosis and diabetes: The RAGE connection
-
Schmidt AM, Stern D. Atherosclerosis and diabetes: the RAGE connection. Curr Atheroscler Rep 2000;2:430-436.
-
(2000)
Curr Atheroscler Rep
, vol.2
, pp. 430-436
-
-
Schmidt, A.M.1
Stern, D.2
-
11
-
-
0030790277
-
Atherogenesis and advanced glycation: Promotion, progression, and prevention
-
Stitt AW, Bucala R, Vlassara H. Atherogenesis and advanced glycation: Promotion, progression, and prevention. Ann NY Acad Sci 1997;811:115-127.
-
(1997)
Ann NY Acad Sci
, vol.811
, pp. 115-127
-
-
Stitt, A.W.1
Bucala, R.2
Vlassara, H.3
-
12
-
-
44449179863
-
Possible involvement of advanced glycation end-products (AGEs) in the pathogenesis of Alzheimer's disease
-
Takeuchi M, Yamagishi S. Possible involvement of advanced glycation end-products (AGEs) in the pathogenesis of Alzheimer's disease. Curr Pharm Des 2008;14:973-978.
-
(2008)
Curr Pharm des
, vol.14
, pp. 973-978
-
-
Takeuchi, M.1
Yamagishi, S.2
-
13
-
-
47049105636
-
Inhibitors of advanced glycation end products (AGEs): Potential utility for the treatment of cardiovascular disease
-
Yamagishi S, Nakamura K, Matsui T, Ueda S, Noda Y, Imaizumi T. Inhibitors of advanced glycation end products (AGEs): Potential utility for the treatment of cardiovascular disease. Cardiovasc Ther 2008;26:50-58.
-
(2008)
Cardiovasc Ther
, vol.26
, pp. 50-58
-
-
Yamagishi, S.1
Nakamura, K.2
Matsui, T.3
Ueda, S.4
Noda, Y.5
Imaizumi, T.6
-
14
-
-
42049109529
-
Receptor for advanced glycation end products (RAGE): A novel therapeutic target for diabetic vascular complications
-
Yamagishi S, Nakamura K, Matsui T, Noda Y, Imaizumi T. Receptor for advanced glycation end products (RAGE): A novel therapeutic target for diabetic vascular complications. Curr Pharm Des 2008;14:487-495.
-
(2008)
Curr Pharm des
, vol.14
, pp. 487-495
-
-
Yamagishi, S.1
Nakamura, K.2
Matsui, T.3
Noda, Y.4
Imaizumi, T.5
-
15
-
-
44449097168
-
AGE-RAGE system and carcinogenesis
-
Abe R, Yamagishi S. AGE-RAGE system and carcinogenesis. Curr Pharm Des 2008;14:940-945.
-
(2008)
Curr Pharm des
, vol.14
, pp. 940-945
-
-
Abe, R.1
Yamagishi, S.2
-
16
-
-
44449114217
-
Advanced glycation end-products and insulin resistance
-
Unoki H, Yamagishi S. Advanced glycation end-products and insulin resistance. Curr Pharm Des 2008;14:977-979.
-
(2008)
Curr Pharm des
, vol.14
, pp. 977-979
-
-
Unoki, H.1
Yamagishi, S.2
-
17
-
-
44449166649
-
Advanced glycation end products (AGEs) and their involvement in liver disease
-
Hyogo H, Yamagishi S. Advanced glycation end products (AGEs) and their involvement in liver disease. Curr Pharm Des 2008;14:969-972.
-
(2008)
Curr Pharm des
, vol.14
, pp. 969-972
-
-
Hyogo, H.1
Yamagishi, S.2
-
18
-
-
69949085013
-
The role of advanced glycation end products in retinal ageing and disease
-
Glenn JV, Stitt AW. The role of advanced glycation end products in retinal ageing and disease. Biochim Biophys Acta 2009;1790:1109-1116.
-
(2009)
Biochim Biophys Acta
, vol.1790
, pp. 1109-1116
-
-
Glenn, J.V.1
Stitt, A.W.2
-
20
-
-
79958158204
-
Vardenafil, an inhibitor of phosphodiesterase-5, blocks advanced glycation end product (age)-induced up-regulation of monocyte chemoattractant protein-1 mrna levels in endothelial cells by suppressing age receptor (rage) expression via elevation of cgmp
-
Ishibashi Y, Matsui T, Takeuchi M, Yamagishi S. Vardenafil, an inhibitor of phosphodiesterase-5, blocks advanced glycation end product (AGE)-induced up-regulation of monocyte chemoattractant protein-1 mRNA levels in endothelial cells by suppressing AGE receptor (RAGE) expression via elevation of cGMP. Clin Exp Med 2011;11:131-135.
-
(2011)
Clin Exp Med
, vol.11
, pp. 131-135
-
-
Ishibashi, Y.1
Matsui, T.2
Takeuchi, M.3
Yamagishi, S.4
-
21
-
-
77954716681
-
Smooth muscle cell pathophysiology and advanced glycation end products (AGEs)
-
Yamagishi S, Matsui T. Smooth muscle cell pathophysiology and advanced glycation end products (AGEs). Curr Drug Targets 2010;11:875-881.
-
(2010)
Curr Drug Targets
, vol.11
, pp. 875-881
-
-
Yamagishi, S.1
Matsui, T.2
-
22
-
-
67651099181
-
Regulation of advanced glycation end product (AGE)-receptor (RAGE) system by PPAR-gamma agonists and its implication in cardiovascular disease
-
Yamagishi S, Nakamura K, Matsui T. Regulation of advanced glycation end product (AGE)-receptor (RAGE) system by PPAR-gamma agonists and its implication in cardiovascular disease. Pharmacol Res 2009;60:174-178.
-
(2009)
Pharmacol Res
, vol.60
, pp. 174-178
-
-
Yamagishi, S.1
Nakamura, K.2
Matsui, T.3
-
23
-
-
15844425230
-
An agent cleaving glucosederived protein crosslinks in vitro and in vivo
-
Vasan S, Zhang X, Zhang X, Kapurniotu A, Bernhagen J, Teichberg S, Basgen J, Wagle D, Shih D, Terlecky I, Bucala R, Cerami A, Egan J, Ulrich P. An agent cleaving glucosederived protein crosslinks in vitro and in vivo. Nature 1996;382:275-278.
-
(1996)
Nature
, vol.382
, pp. 275-278
-
-
Vasan, S.1
Zhang, X.2
Zhang, X.3
Kapurniotu, A.4
Bernhagen, J.5
Teichberg, S.6
Basgen, J.7
Wagle, D.8
Shih, D.9
Terlecky, I.10
Bucala, R.11
Cerami, A.12
Egan, J.13
Ulrich, P.14
-
24
-
-
0032515986
-
Breakers of advanced glycation end products restore large artery properties in experimental diabetes
-
Wolffenbuttel BH, Boulanger CM, Crijns FR, Huijberts MS, Poitevin P, Swennen GN, Vasan S, Egan JJ, Ulrich P, Cerami A, Le'vy BI. Breakers of advanced glycation end products restore large artery properties in experimental diabetes. Proc Natl Acad Sci USA 1998;95:4630-4634.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 4630-4634
-
-
Wolffenbuttel, B.H.1
Boulanger, C.M.2
Crijns, F.R.3
Huijberts, M.S.4
Poitevin, P.5
Swennen, G.N.6
Vasan, S.7
Egan, J.J.8
Ulrich, P.9
Cerami, A.10
Le'Vy, B.I.11
-
25
-
-
36949037321
-
Beneficial effects of C36, a novel breaker of advanced glycationendproducts cross-links, on the cardiovascular system of diabetic rats
-
Cheng G, Wang LL, Long L, Liu HY, Cui H, Qu WS, Li S. Beneficial effects of C36, a novel breaker of advanced glycationendproducts cross-links, on the cardiovascular system of diabetic rats. Br J Pharmacol 2007;152:1196-1206.
-
(2007)
Br J Pharmacol
, vol.152
, pp. 1196-1206
-
-
Cheng, G.1
Wang, L.L.2
Long, L.3
Liu, H.Y.4
Cui, H.5
Qu, W.S.6
Li, S.7
-
26
-
-
29044432819
-
C16, a novel advanced glycation endproduct breaker, restores cardiovascular dysfunction in experimental diabetic rats
-
Cheng G, Wang LL, Qu WS, Long L, Cui H, Liu HY, Cao YL, Li S. C16, a novel advanced glycation endproduct breaker, restores cardiovascular dysfunction in experimental diabetic rats. Acta Pharmacol Sin 2005;26:1460-1466.
-
(2005)
Acta Pharmacol Sin
, vol.26
, pp. 1460-1466
-
-
Cheng, G.1
Wang, L.L.2
Qu, W.S.3
Long, L.4
Cui, H.5
Liu, H.Y.6
Cao, Y.L.7
Li, S.8
-
27
-
-
34548484348
-
Arterial stiffness as a risk factor for coronary atherosclerosis
-
Duprez DA, Cohn JN. Arterial stiffness as a risk factor for coronary atherosclerosis. Curr Atheroscler Rep 2007;9:139- 144.
-
(2007)
Curr Atheroscler Rep
, vol.9
, pp. 139-144
-
-
Duprez, D.A.1
Cohn, J.N.2
-
28
-
-
34250711700
-
Arterial stiffness and cardiovascular outcome
-
Zoungas S, Asmar RP. Arterial stiffness and cardiovascular outcome. Clin Exp Pharmacol Physiol 2007;34:647-651.
-
(2007)
Clin Exp Pharmacol Physiol
, vol.34
, pp. 647-651
-
-
Zoungas, S.1
Asmar, R.P.2
-
29
-
-
33644976911
-
Ambulatory arterial stiffness index as a predictor of cardiovascular mortality in the Dublin Outcome Study
-
Dolan E, Thijs L, Li Y, Atkins N, McCormack P, McClory S, O'Brien E, Staessen JA, Stanton AV. Ambulatory arterial stiffness index as a predictor of cardiovascular mortality in the Dublin Outcome Study. Hypertension 2006;47:365-370.
-
(2006)
Hypertension
, vol.47
, pp. 365-370
-
-
Dolan, E.1
Thijs, L.2
Li, Y.3
Atkins, N.4
McCormack, P.5
McClory, S.6
O'Brien, E.7
Staessen, J.A.8
Stanton, A.V.9
-
30
-
-
33751097470
-
Arterial stiffness and extracellular matrix
-
Diez J. Arterial stiffness and extracellular matrix. Adv Cardiol 2007;44:76-95.
-
(2007)
Adv Cardiol
, vol.44
, pp. 76-95
-
-
Diez, J.1
-
31
-
-
78349269124
-
Aging and arterial stiffness
-
Lee HY, Oh BH. Aging and arterial stiffness. Circ J 2010;74: 2257-2262.
-
(2010)
Circ J
, vol.74
, pp. 2257-2262
-
-
Lee, H.Y.1
Oh, B.H.2
-
32
-
-
1842510005
-
Cardiovascular and renal effects of a collagen cross-link breaker (ALT 711) in adult and aged spontaneously hypertensive rats
-
Susic D, Varagic J, Ahn J, Frohlich ED. Cardiovascular and renal effects of a collagen cross-link breaker (ALT 711) in adult and aged spontaneously hypertensive rats. Am J Hypertens 2004;17:328-333.
-
(2004)
Am J Hypertens
, vol.17
, pp. 328-333
-
-
Susic, D.1
Varagic, J.2
Ahn, J.3
Frohlich, E.D.4
-
33
-
-
52149110139
-
Advanced glycation end products accumulate in vascular smooth muscle and modify vascular but not ventricular properties in elderly hypertensive canines
-
Shapiro BP, Owan TE, Mohammed SF, Meyer DM, Mills LD, Schalkwijk CG, et al. Advanced glycation end products accumulate in vascular smooth muscle and modify vascular but not ventricular properties in elderly hypertensive canines. Circulation 2008;118:1002-1010.
-
(2008)
Circulation
, vol.118
, pp. 1002-1010
-
-
Shapiro, B.P.1
Owan, T.E.2
Mohammed, S.F.3
Meyer, D.M.4
Mills, L.D.5
Schalkwijk, C.G.6
-
34
-
-
0035949502
-
Improved arterial compliance by a novel advanced glycation end-product crosslink breaker
-
Kass DA, Shapiro EP, Kawaguchi M, Capriotti AR, Scuteri A, deGroof RC, Redfield MM. Improved arterial compliance by a novel advanced glycation end-product crosslink breaker. Circulation 2001;104:1464-1470.
-
(2001)
Circulation
, vol.104
, pp. 1464-1470
-
-
Kass, D.A.1
Shapiro, E.P.2
Kawaguchi, M.3
Capriotti, A.R.4
Scuteri, A.5
Degroof, R.C.6
Redfield, M.M.7
-
35
-
-
33846849277
-
Advanced glycation endproduct crosslink breaker (alagebrium) improves endothelialfunction in patients with isolated systolic hypertension
-
Zieman SJ, Melenovsky V, Clattenburg L, Corretti MC, Capriotti A, Gerstenblith G, Kass DA. Advanced glycation endproduct crosslink breaker (alagebrium) improves endothelialfunction in patients with isolated systolic hypertension. J Hypertens 2007;25:577-583.
-
(2007)
J Hypertens
, vol.25
, pp. 577-583
-
-
Zieman, S.J.1
Melenovsky, V.2
Clattenburg, L.3
Corretti, M.C.4
Capriotti, A.5
Gerstenblith, G.6
Kass, D.A.7
-
36
-
-
33847112020
-
Advanced glycation endproducts and arterial stiffness in hypertension
-
McNulty M, Mahmud A, Feely J. Advanced glycation endproducts and arterial stiffness in hypertension. Am J Hypertens 2007;20:242-247.
-
(2007)
Am J Hypertens
, vol.20
, pp. 242-247
-
-
McNulty, M.1
Mahmud, A.2
Feely, J.3
-
37
-
-
77956819409
-
Advanced glycation end-products induce vascular dysfunction via resistance to nitric oxide and suppression of endothelial nitric oxide synthase
-
Soro-Paavonen A, Zhang WZ, Venardos K, Coughlan MT, Harris E, Tong DC, Brasacchio D, Paavonen K, Chin- Dusting J, Cooper ME, Kaye D, Thomas MC, Forbes JM. Advanced glycation end-products induce vascular dysfunction via resistance to nitric oxide and suppression of endothelial nitric oxide synthase. J Hypertens 2010;28: 780-788.
-
(2010)
J Hypertens
, vol.28
, pp. 780-788
-
-
Soro-Paavonen, A.1
Zhang, W.Z.2
Venardos, K.3
Coughlan, M.T.4
Harris, E.5
Tong, D.C.6
Brasacchio, D.7
Paavonen, K.8
Chin- Dusting, J.9
Cooper, M.E.10
Kaye, D.11
Thomas, M.C.12
Forbes, J.M.13
-
38
-
-
29144460968
-
Preservation of pressure-induced cutaneous vasodilation by limiting oxidative stress in short-term diabetic mice
-
Demiot C, Fromy B, Saumet JL, Sigaudo-Roussel D. Preservation of pressure-induced cutaneous vasodilation by limiting oxidative stress in short-term diabetic mice. Cardiovasc Res 2006;69:245-252.
-
(2006)
Cardiovasc Res
, vol.69
, pp. 245-252
-
-
Demiot, C.1
Fromy, B.2
Saumet, J.L.3
Sigaudo-Roussel, D.4
-
39
-
-
3042704196
-
Advanced glycation end product interventions reduce diabetes-accelerated atherosclerosis
-
Forbes JM, Yee LT, Thallas V, Lassila M, Candido R, Jandeleit- Dahm KA, Thomas MC, Burns WC, Deemer EK, Thorpe SR, Cooper ME, Allen TJ. Advanced glycation end product interventions reduce diabetes-accelerated atherosclerosis. Diabetes 2004;53:1813-1823.
-
(2004)
Diabetes
, vol.53
, pp. 1813-1823
-
-
Forbes, J.M.1
Yee, L.T.2
Thallas, V.3
Lassila, M.4
Candido, R.5
Jandeleit-Dahm, K.A.6
Thomas, M.C.7
Burns, W.C.8
Deemer, E.K.9
Thorpe, S.R.10
Cooper, M.E.11
Allen, T.J.12
-
40
-
-
79953730567
-
Delayed intervention with AGE inhibitors attenuates the progression of diabetesaccelerated atherosclerosis in diabetic apolipoprotein e knockout mice
-
Watson AM, Soro-Paavonen A, Sheehy K, Li J, Calkin AC, Koitka A, Rajan SN, Brasacchio D, Allen TJ, Cooper ME, Thomas MC, Jandeleit-Dahm KJ. Delayed intervention with AGE inhibitors attenuates the progression of diabetesaccelerated atherosclerosis in diabetic apolipoprotein E knockout mice. Diabetologia. 2011;54:681-169.
-
(2011)
Diabetologia
, vol.54
, pp. 681-169
-
-
Watson, A.M.1
Soro-Paavonen, A.2
Sheehy, K.3
Li, J.4
Calkin, A.C.5
Koitka, A.6
Rajan, S.N.7
Brasacchio, D.8
Allen, T.J.9
Cooper, M.E.10
Thomas, M.C.11
Jandeleit-Dahm, K.J.12
-
41
-
-
78649411753
-
Alagebrium chloride, a novel advanced glycation end-product cross linkage breaker, inhibits neointimal proliferation in a diabetic rat carotid balloon injury model
-
Kim JB, Song BW, Park S, Hwang KC, Cha BS, Jang Y, Lee HC, Lee MH. Alagebrium chloride, a novel advanced glycation end-product cross linkage breaker, inhibits neointimal proliferation in a diabetic rat carotid balloon injury model. Korean Circ J 2010;40:520-526.
-
(2010)
Korean Circ J
, vol.40
, pp. 520-526
-
-
Kim, J.B.1
Song, B.W.2
Park, S.3
Hwang, K.C.4
Cha, B.S.5
Jang, Y.6
Lee, H.C.7
Lee, M.H.8
-
42
-
-
64249090462
-
Methylglyoxal-induced mitochondrial dysfunction in vascular smooth muscle cells
-
Wang H, Liu J, Wu L. Methylglyoxal-induced mitochondrial dysfunction in vascular smooth muscle cells. Biochem Pharmacol 2009;77:1709-1716.
-
(2009)
Biochem Pharmacol
, vol.77
, pp. 1709-1716
-
-
Wang, H.1
Liu, J.2
Wu, L.3
-
43
-
-
77956638706
-
ATP-binding membrane cassette transporter A1 (ABCA1): A possible link between inflammation and reverse cholesterol transport
-
Yin K, Liao DF, Tang CK. ATP-binding membrane cassette transporter A1 (ABCA1): A possible link between inflammation and reverse cholesterol transport. Mol Med 2010;16:438-449.
-
(2010)
Mol Med
, vol.16
, pp. 438-449
-
-
Yin, K.1
Liao, D.F.2
Tang, C.K.3
-
45
-
-
42649134146
-
HDL ABC transporters, and cholesterol efflux: Implications for the treatment of atherosclerosis
-
Tall AR, Yvan-Charvet L, Terasaka N, Pagler T, Wang N. HDL, ABC transporters, and cholesterol efflux: Implications for the treatment of atherosclerosis. Cell Metab 2008;7:365-375.
-
(2008)
Cell Metab
, vol.7
, pp. 365-375
-
-
Tall, A.R.1
Yvan-Charvet, L.2
Terasaka, N.3
Pagler, T.4
Wang, N.5
-
46
-
-
75149124430
-
Role of HDL ABCA1, and ABCG1 transporters in cholesterol efflux and immune responses
-
Yvan-Charvet L, Wang N, Tall AR. Role of HDL, ABCA1, and ABCG1 transporters in cholesterol efflux and immune responses. Arterioscler Thromb Vasc Biol 2010;30:139-143.
-
(2010)
Arterioscler Thromb Vasc Biol
, vol.30
, pp. 139-143
-
-
Yvan-Charvet, L.1
Wang, N.2
Tall, A.R.3
-
47
-
-
36849011221
-
Combined deficiency of ABCA1 and ABCG1 promotes foam cell accumulation and accelerates atherosclerosis in mice
-
Yvan-Charvet L, Ranalletta M, Wang N, Han S, Terasaka N, Li R, Welch C, Tall AR. Combined deficiency of ABCA1 and ABCG1 promotes foam cell accumulation and accelerates atherosclerosis in mice. J Clin Invest 2007;117:3900- 3908.
-
(2007)
J Clin Invest
, vol.117
, pp. 3900-3908
-
-
Yvan-Charvet, L.1
Ranalletta, M.2
Wang, N.3
Han, S.4
Terasaka, N.5
Li, R.6
Welch, C.7
Tall, A.R.8
-
48
-
-
0141835080
-
Clinical significance of high-density lipoproteins and the development of atherosclerosis: Focus on the role of the adenosine triphosphatebinding cassette protein A1 transporter
-
Brewer HB Jr, Santamarina-Fojo S. Clinical significance of high-density lipoproteins and the development of atherosclerosis: Focus on the role of the adenosine triphosphatebinding cassette protein A1 transporter. Am J Cardiol 2003;92:10K-16K.
-
(2003)
Am J Cardiol
, vol.92
-
-
Brewer Jr., H.B.1
Santamarina-Fojo, S.2
-
49
-
-
80051783796
-
Rosuvastatin blocks advanced glycation end products-elicited reduction of macrophage cholesterol efflux by suppressing NADPH oxidase activity via inhibition of geranylgeranylation of Rac-1
-
Ishibashi Y, Matsui T, Takeuchi M, Yamagishi S. Rosuvastatin blocks advanced glycation end products-elicited reduction of macrophage cholesterol efflux by suppressing NADPH oxidase activity via inhibition of geranylgeranylation of Rac-1. Horm Metab Res 2011;43:619-624.
-
(2011)
Horm Metab Res
, vol.43
, pp. 619-624
-
-
Ishibashi, Y.1
Matsui, T.2
Takeuchi, M.3
Yamagishi, S.4
-
50
-
-
34447117721
-
Advanced glycation of apolipoprotein A-I impairs its antiatherogenic properties
-
Hoang A, Murphy AJ, Coughlan MT, Thomas MC, Forbes JM, O'Brien R, Cooper ME, Chin-Dusting JP, Sviridov D. Advanced glycation of apolipoprotein A-I impairs its antiatherogenic properties. Diabetologia 2007;50:1770-1779.
-
(2007)
Diabetologia
, vol.50
, pp. 1770-1779
-
-
Hoang, A.1
Murphy, A.J.2
Coughlan, M.T.3
Thomas, M.C.4
Forbes, J.M.5
O'Brien, R.6
Cooper, M.E.7
Chin-Dusting, J.P.8
Sviridov, D.9
-
51
-
-
43049144209
-
Effects of cross-link breakers, glycation inhibitors and insulin sensitisers on HDL function and the nonenzymatic glycation of apolipoprotein A-I
-
Nobe'court E, Zeng J, Davies MJ, Brown BE, Yadav S, Barter PJ, Rye KA. Effects of cross-link breakers, glycation inhibitors and insulin sensitisers on HDL function and the nonenzymatic glycation of apolipoprotein A-I. Diabetologia 2008;51:1008-1017.
-
(2008)
Diabetologia
, vol.51
, pp. 1008-1017
-
-
Nobe'Court, E.1
Zeng, J.2
Davies, M.J.3
Brown, B.E.4
Yadav, S.5
Barter, P.J.6
Rye, K.A.7
-
52
-
-
0037453647
-
A breaker of advanced glycation end products attenuates diabetes-induced myocardial structural changes
-
Candido R, Forbes JM, Thomas MC, Thallas V, Dean RG, Burns WC, Tikellis C, Ritchie RH, Twigg SM, Cooper ME, Burrell LM. A breaker of advanced glycation end products attenuates diabetes-induced myocardial structural changes. Circ Res 2003;92:785-792.
-
(2003)
Circ Res
, vol.92
, pp. 785-792
-
-
Candido, R.1
Forbes, J.M.2
Thomas, M.C.3
Thallas, V.4
Dean, R.G.5
Burns, W.C.6
Tikellis, C.7
Ritchie, R.H.8
Twigg, S.M.9
Cooper, M.E.10
Burrell, L.M.11
-
53
-
-
66149139773
-
Alagebrium chloride protects the heart against oxidative stress in aging rats
-
Guo Y, Lu M, Qian J, Cheng YL. Alagebrium chloride protects the heart against oxidative stress in aging rats. J Gerontol A Biol Sci Med Sci 2009;64:629-635.
-
(2009)
J Gerontol A Biol Sci Med Sci
, vol.64
, pp. 629-635
-
-
Guo, Y.1
Lu, M.2
Qian, J.3
Cheng, Y.L.4
-
54
-
-
0034646372
-
An advanced glycation endproduct cross-link breaker can reverse age-related increases in myocardial stiffness
-
Asif M, Egan J, Vasan S, Jyothirmayi GN, Masurekar MR, Lopez S, Williams C, Torres RL, Wagle D, Ulrich P, Cerami A, Brines M, Regan TJ. An advanced glycation endproduct cross-link breaker can reverse age-related increases in myocardial stiffness. Proc Natl Acad Sci USA 2000;97:2809-2813.
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 2809-2813
-
-
Asif, M.1
Egan, J.2
Vasan, S.3
Jyothirmayi, G.N.4
Masurekar, M.R.5
Lopez, S.6
Williams, C.7
Torres, R.L.8
Wagle, D.9
Ulrich, P.10
Cerami, A.11
Brines, M.12
Regan, T.J.13
-
55
-
-
0345303768
-
Glycation endproduct cross-link breaker reduces collagen and improves cardiac function in aging diabetic heart
-
Liu J, Masurekar MR, Vatner DE, Jyothirmayi GN, Regan TJ, Vatner SF, Meggs LG, Malhotra A. Glycation endproduct cross-link breaker reduces collagen and improves cardiac function in aging diabetic heart. Am J Physiol Heart Circ Physiol 2003;285:H2587-H2591.
-
(2003)
Am J Physiol Heart Circ Physiol
, vol.285
-
-
Liu, J.1
Masurekar, M.R.2
Vatner, D.E.3
Jyothirmayi, G.N.4
Regan, T.J.5
Vatner, S.F.6
Meggs, L.G.7
Malhotra, A.8
-
56
-
-
0035970120
-
A cross-link breaker has sustained effects on arterial and ventricular properties in older rhesus monkeys
-
Vaitkevicius PV, Lane M, Spurgeon H, Ingram DK, Roth GS, Egan JJ, Vasan S, Wagle DR, Ulrich P, Brines M, Wuerth JP, Cerami A, Lakatta EG. A cross-link breaker has sustained effects on arterial and ventricular properties in older rhesus monkeys. Proc Natl Acad Sci USA 2001;98:1171-1175.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 1171-1175
-
-
Vaitkevicius, P.V.1
Lane, M.2
Spurgeon, H.3
Ingram, D.K.4
Roth, G.S.5
Egan, J.J.6
Vasan, S.7
Wagle, D.R.8
Ulrich, P.9
Brines, M.10
Wuerth, J.P.11
Cerami, A.12
Lakatta, E.G.13
-
57
-
-
52649114296
-
Cardiac inflammation associated with a Western diet is mediated via activation of RAGE by AGEs
-
Tikellis C, Thomas MC, Harcourt BE, Coughlan MT, Pete J, Bialkowski K, Tan A, Bierhaus A, Cooper ME, Forbes JM. Cardiac inflammation associated with a Western diet is mediated via activation of RAGE by AGEs. Am J Physiol Endocrinol Metab 2008;295:E323-E330.
-
(2008)
Am J Physiol Endocrinol Metab
, vol.295
-
-
Tikellis, C.1
Thomas, M.C.2
Harcourt, B.E.3
Coughlan, M.T.4
Pete, J.5
Bialkowski, K.6
Tan, A.7
Bierhaus, A.8
Cooper, M.E.9
Forbes, J.M.10
-
58
-
-
16244371321
-
The effect of alagebrium chloride (ALT- 711), a novel glucose cross-link breaker, in the treatment of elderly patients with diastolic heart failure
-
Little WC, Zile MR, Kitzman DW, Hundley WG, O'Brien TX, Degroof RC. The effect of alagebrium chloride (ALT- 711), a novel glucose cross-link breaker, in the treatment of elderly patients with diastolic heart failure. J Card Fail 2005;11:191-195.
-
(2005)
J Card Fail
, vol.11
, pp. 191-195
-
-
Little, W.C.1
Zile, M.R.2
Kitzman, D.W.3
Hundley, W.G.4
O'Brien, T.X.5
Degroof, R.C.6
-
59
-
-
77249098721
-
Effects of alagebrium, an advanced glycation end-product breaker, in patients with chronic heart failure: Study design and baseline characteristics of the BENEFICIAL trial
-
Willemsen S, Hartog JW, Hummel YM, Posma JL, van Wijk LM, van Veldhuisen DJ, Voors AA. Effects of alagebrium, an advanced glycation end-product breaker, in patients with chronic heart failure: Study design and baseline characteristics of the BENEFICIAL trial. Eur J Heart Fail. 2010;12:294-300.
-
(2010)
Eur J Heart Fail
, vol.12
, pp. 294-300
-
-
Willemsen, S.1
Hartog, J.W.2
Hummel, Y.M.3
Posma, J.L.4
Van Wijk, L.M.5
Van Veldhuisen, D.J.6
Voors, A.A.7
-
60
-
-
79961098801
-
Effects of alagebrium, an advanced glycation endproduct breaker, on exercise tolerance and cardiac function in patients with chronic heart failure
-
Hartog JW, Willemsen S, van Veldhuisen DJ, Posma JL, van Wijk LM, Hummel YM, et al. Effects of alagebrium, an advanced glycation endproduct breaker, on exercise tolerance and cardiac function in patients with chronic heart failure. Eur J Heart Fail 2011;13:899-908.
-
(2011)
Eur J Heart Fail
, vol.13
, pp. 899-908
-
-
Hartog, J.W.1
Willemsen, S.2
Van Veldhuisen, D.J.3
Posma, J.L.4
Van Wijk, L.M.5
Hummel, Y.M.6
-
61
-
-
34548397224
-
Molecular mechanisms of diabetic nephropathy and its therapeutic intervention
-
Yamagishi S, Fukami K, Ueda S, Okuda S. Molecular mechanisms of diabetic nephropathy and its therapeutic intervention. Curr Drug Targets 2007;8:95295-95299.
-
(2007)
Curr Drug Targets
, vol.8
, pp. 95295-95299
-
-
Yamagishi, S.1
Fukami, K.2
Ueda, S.3
Okuda, S.4
-
62
-
-
0027930904
-
Clinical and histological correlations of decline in renal function in diabetic patients with proteinuria
-
Taft JL, Nolan CJ, Yeung SP, Hewitson TD, Martin FI. Clinical and histological correlations of decline in renal function in diabetic patients with proteinuria. Diabetes 1994;43:1046-1051.
-
(1994)
Diabetes
, vol.43
, pp. 1046-1051
-
-
Taft, J.L.1
Nolan, C.J.2
Yeung, S.P.3
Hewitson, T.D.4
Martin, F.I.5
-
63
-
-
0025732119
-
The renal tubulointerstitium in diabetes mellitus
-
Ziyadeh FN, Goldfarb S. The renal tubulointerstitium in diabetes mellitus. Kidney Int 1991;39:464-475.
-
(1991)
Kidney Int
, vol.39
, pp. 464-475
-
-
Ziyadeh, F.N.1
Goldfarb, S.2
-
64
-
-
0035661067
-
Advanced glycation end products cause epithelial- myofibroblast transdifferentiation via the receptor for advanced glycation end products (RAGE)
-
Oldfield MD, Bach LA, Forbes JM, Nikolic-Paterson D, McRobert A, Thallas V, Atkins RC, Osicka T, Jerums G, Cooper ME. Advanced glycation end products cause epithelial- myofibroblast transdifferentiation via the receptor for advanced glycation end products (RAGE). J Clin Invest 2001;108:1853-1863.
-
(2001)
J Clin Invest
, vol.108
, pp. 1853-1863
-
-
Oldfield, M.D.1
Bach, L.A.2
Forbes, J.M.3
Nikolic-Paterson, D.4
McRobert, A.5
Thallas, V.6
Atkins, R.C.7
Osicka, T.8
Jerums, G.9
Cooper, M.E.10
-
65
-
-
0141483457
-
The breakdown of preexisting advanced glycation end products is associated with reduced renal fibrosis in experimental diabetes
-
Forbes JM, Thallas V, Thomas MC, Founds HW, Burns WC, Jerums G, Cooper ME. The breakdown of preexisting advanced glycation end products is associated with reduced renal fibrosis in experimental diabetes. FASEB J 2003;17: 1762-1764.
-
(2003)
FASEB J
, vol.17
, pp. 1762-1764
-
-
Forbes, J.M.1
Thallas, V.2
Thomas, M.C.3
Founds, H.W.4
Burns, W.C.5
Jerums, G.6
Cooper, M.E.7
-
66
-
-
80155172655
-
Renoprotective antioxidant effect of alagebrium in experimental diabetes
-
Park J, Kwon MK, Huh JY, Choi WJ, Jeong LS, Nagai R, Kim WY, Kim J, Lee GT, Lee HB, Ha H. Renoprotective antioxidant effect of alagebrium in experimental diabetes. Nephrol Dial Transplant 2011;26:3474-3484.
-
(2011)
Nephrol Dial Transplant
, vol.26
, pp. 3474-3484
-
-
Park, J.1
Kwon, M.K.2
Huh, J.Y.3
Choi, W.J.4
Jeong, L.S.5
Nagai, R.6
Kim, W.Y.7
Kim, J.8
Lee, G.T.9
Lee, H.B.10
Ha, H.11
-
67
-
-
7044231909
-
Attenuation of extracellular matrix accumulation in diabetic nephropathy by the advanced glycation end product cross-link breaker ALT-711 via a protein kinase C-alpha-dependent pathway
-
Thallas-Bonke V, Lindschau C, Rizkalla B, Bach LA, Boner G, Meier M, Haller H, Cooper ME, Forbes JM. Attenuation of extracellular matrix accumulation in diabetic nephropathy by the advanced glycation end product cross-link breaker ALT-711 via a protein kinase C-alpha-dependent pathway. Diabetes 2004;53:2921-2930.
-
(2004)
Diabetes
, vol.53
, pp. 2921-22930
-
-
Thallas-Bonke, V.1
Lindschau, C.2
Rizkalla, B.3
Bach, L.A.4
Boner, G.5
Meier, M.6
Haller, H.7
Cooper, M.E.8
Forbes, J.M.9
-
68
-
-
65249153029
-
RAGE-induced cytosolic ROS promote mitochondrial superoxide generation in diabetes
-
Coughlan MT, Thorburn DR, Penfold SA, Laskowski A, Harcourt BE, Sourris KC, Tan AL, Fukami K, Thallas-Bonke V, Nawroth PP, Brownlee M, Bierhaus A, Cooper ME, Forbes JM. RAGE-induced cytosolic ROS promote mitochondrial superoxide generation in diabetes. J Am Soc Nephrol 2009;20:742-752.
-
(2009)
J Am Soc Nephrol
, vol.20
, pp. 742-752
-
-
Coughlan, M.T.1
Thorburn, D.R.2
Penfold, S.A.3
Laskowski, A.4
Harcourt, B.E.5
Sourris, K.C.6
Tan, A.L.7
Fukami, K.8
Thallas-Bonke, V.9
Nawroth, P.P.10
Brownlee, M.11
Bierhaus, A.12
Cooper, M.E.13
Forbes, J.M.14
-
69
-
-
3543148984
-
Accelerated nephropathy in diabetic apolipoprotein e-knockout mouse: Role of advanced glycation end products
-
Lassila M, Seah KK, Allen TJ, Thallas V, Thomas MC, Candido R, Burns WC, Forbes JM, Calkin AC, Cooper ME, Jandeleit-Dahm KA. Accelerated nephropathy in diabetic apolipoprotein e-knockout mouse: Role of advanced glycation end products. J Am Soc Nephrol 2004;15:2125-2138.
-
(2004)
J Am Soc Nephrol
, vol.15
, pp. 2125-2138
-
-
Lassila, M.1
Seah, K.K.2
Allen, T.J.3
Thallas, V.4
Thomas, M.C.5
Candido, R.6
Burns, W.C.7
Forbes, J.M.8
Calkin, A.C.9
Cooper, M.E.10
Jandeleit-Dahm, K.A.11
-
70
-
-
79959797020
-
Targeted reduction of advanced glycation improves renal function in obesity
-
Harcourt BE, Sourris KC, Coughlan MT, Walker KZ, Dougherty SL, Andrikopoulos S, Morley AL, Thallas-Bonke V, Chand V, Penfold SA, de Courten MP, Thomas MC, Kingwell BA, Bierhaus A, Cooper ME, Courten B, Forbes JM. Targeted reduction of advanced glycation improves renal function in obesity. Kidney Int 2011;80:190-198.
-
(2011)
Kidney Int
, vol.80
, pp. 190-198
-
-
Harcourt, B.E.1
Sourris, K.C.2
Coughlan, M.T.3
Walker, K.Z.4
Dougherty, S.L.5
Andrikopoulos, S.6
Morley, A.L.7
Thallas-Bonke, V.8
Chand, V.9
Penfold, S.A.10
De Courten, M.P.11
Thomas, M.C.12
Kingwell, B.A.13
Bierhaus, A.14
Cooper, M.E.15
Courten, B.16
Forbes, J.M.17
-
71
-
-
62449320294
-
The breakdown of preformed peritoneal advanced glycation end products by intraperitoneal alagebrium
-
Lee YK, Lee JY, Kim JS, Won KB, Kang HJ, Jang TJ, Tak WT, Lee JH. The breakdown of preformed peritoneal advanced glycation end products by intraperitoneal alagebrium. J Korean Med Sci 2009;Suppl:S189-S194.
-
(2009)
J Korean Med Sci
, vol.SUPPL.
-
-
Lee, Y.K.1
Lee, J.Y.2
Kim, J.S.3
Won, K.B.4
Kang, H.J.5
Jang, T.J.6
Tak, W.T.7
Lee, J.H.8
-
72
-
-
80053408093
-
Advanced glycation end products are direct modulators of b-cell function
-
Coughlan MT, Yap FY, Tong DC, Andrikopoulos S, Gasser A, Thallas-Bonke V, Webster DE, Miyazaki J, Kay TW, Slattery RM, Kaye DM, Drew BG, Kingwell BA, Fourlanos S, Groop PH, Harrison LC, Knip M, Forbes JM. Advanced glycation end products are direct modulators of b-cell function. Diabetes 2011;60:2523-2532.
-
(2011)
Diabetes
, vol.60
, pp. 2523-2532
-
-
Coughlan, M.T.1
Yap, F.Y.2
Tong, D.C.3
Andrikopoulos, S.4
Gasser, A.5
Thallas-Bonke, V.6
Webster, D.E.7
Miyazaki, J.8
Kay, T.W.9
Slattery, R.M.10
Kaye, D.M.11
Drew, B.G.12
Kingwell, B.A.13
Fourlanos, S.14
Groop, P.H.15
Harrison, L.C.16
Knip, M.17
Forbes, J.M.18
-
73
-
-
79952403213
-
Chronic methylglyoxal infusion by minipump causes pancreatic beta-cell dysfunction and induces type 2 diabetes in Sprague- Dawley rats
-
Dhar A, Dhar I, Jiang B, Desai KM, Wu L. Chronic methylglyoxal infusion by minipump causes pancreatic beta-cell dysfunction and induces type 2 diabetes in Sprague- Dawley rats. Diabetes 2011;60:899-908.
-
(2011)
Diabetes
, vol.60
, pp. 899-908
-
-
Dhar, A.1
Dhar, I.2
Jiang, B.3
Desai, K.M.4
Wu, L.5
-
74
-
-
74549163524
-
Alagebrium attenuates acute methylglyoxal-induced glucose intolerance in sprague- dawley rats
-
Dhar A, Desai KM, Wu L. Alagebrium attenuates acute methylglyoxal-induced glucose intolerance in Sprague- Dawley rats. Br J Pharmacol 2010;159:166-175.
-
(2010)
Br J Pharmacol
, vol.159
, pp. 166-175
-
-
Dhar, A.1
Desai, K.M.2
Wu, L.3
-
75
-
-
33947115243
-
Advanced glycation end products attenuate cellular insulin sensitivity by increasing the generation of intracellular reactive oxygen species in adipocytes
-
Unoki H, Bujo H, Yamagishi S, Takeuchi M, Imaizumi T, Saito Y. Advanced glycation end products attenuate cellular insulin sensitivity by increasing the generation of intracellular reactive oxygen species in adipocytes. Diabetes Res Clin Pract 2007;76:236-244.
-
(2007)
Diabetes Res Clin Pract
, vol.76
, pp. 236-244
-
-
Unoki, H.1
Bujo, H.2
Yamagishi, S.3
Takeuchi, M.4
Imaizumi, T.5
Saito, Y.6
-
76
-
-
53649086825
-
Pigment epithelium- derived factor (PEDF) ameliorates advanced glycation end product (AGE)-induced hepatic insulin resistance in vitro by suppressing Rac-1 activation
-
Yoshida T, Yamagishi S, Nakamura K, Matsui T, Imaizumi T, Takeuchi M, Koga H, Ueno T, Sata M. Pigment epithelium- derived factor (PEDF) ameliorates advanced glycation end product (AGE)-induced hepatic insulin resistance in vitro by suppressing Rac-1 activation. Horm Metab Res 2008;40:620-625.
-
(2008)
Horm Metab Res
, vol.40
, pp. 620-625
-
-
Yoshida, T.1
Yamagishi, S.2
Nakamura, K.3
Matsui, T.4
Imaizumi, T.5
Takeuchi, M.6
Koga, H.7
Ueno, T.8
Sata, M.9
-
77
-
-
78650161056
-
Pyridoxamine, an inhibitor of advanced glycation end product (AGE) formation ameliorates insulin resistance in obese, type 2 diabetic mice
-
Unoki-Kubota H, Yamagishi S, Takeuchi M, Bujo H, Saito Y. Pyridoxamine, an inhibitor of advanced glycation end product (AGE) formation ameliorates insulin resistance in obese, type 2 diabetic mice. Protein Pept Lett 2010;17:1177- 1181.
-
(2010)
Protein Pept Lett
, vol.17
, pp. 1177-1181
-
-
Unoki-Kubota, H.1
Yamagishi, S.2
Takeuchi, M.3
Bujo, H.4
Saito, Y.5
-
78
-
-
65549160061
-
Atheroprotective properties of pigment epithelium-derived factor (PEDF) in cardiometabolic disorders
-
Yamagishi S, Matsui T, Nakamura K. Atheroprotective properties of pigment epithelium-derived factor (PEDF) in cardiometabolic disorders. Curr Pharm Des 2009;15:1027- 1033.
-
(2009)
Curr Pharm des
, vol.15
, pp. 1027-1033
-
-
Yamagishi, S.1
Matsui, T.2
Nakamura, K.3
-
79
-
-
84856252632
-
Serum levels of advanced glycation end products (AGEs) are independent correlates of insulin resistance in nondiabetic subjects
-
Tahara N, Yamagishi S, Matsui T, Takeuchi M, Nitta Y, Kodama N, Mizoguchi M, Imaizumi T. Serum levels of advanced glycation end products (AGEs) are independent correlates of insulin resistance in nondiabetic subjects. Cardiovasc Ther 2012;30:42-48.
-
(2012)
Cardiovasc Ther
, vol.30
, pp. 42-48
-
-
Tahara, N.1
Yamagishi, S.2
Matsui, T.3
Takeuchi, M.4
Nitta, Y.5
Kodama, N.6
Mizoguchi, M.7
Imaizumi, T.8
-
80
-
-
80055003490
-
Eye lens in aging and diabetes: Effect of quercetin
-
Stefek M, Karasu C. Eye lens in aging and diabetes: Effect of quercetin. Rejuvenation Res 2011;14:525-534.
-
(2011)
Rejuvenation Res
, vol.14
, pp. 525-534
-
-
Stefek, M.1
Karasu, C.2
-
81
-
-
11144324314
-
Advanced glycation endproducts - Role in pathology of diabetic complications
-
Ahmed N. Advanced glycation endproducts - role in pathology of diabetic complications. Diabetes Res Clin Pract 2005;67:3-21.
-
(2005)
Diabetes Res Clin Pract
, vol.67
, pp. 3-21
-
-
Ahmed, N.1
-
82
-
-
0037281152
-
Cleavage of in vitro and in vivo formed lens protein crosslinks by a novel cross-link breaker
-
Hollenbach S, Thampi P, Viswanathan T, Abraham EC. Cleavage of in vitro and in vivo formed lens protein crosslinks by a novel cross-link breaker. Mol Cell Biochem 2003;243:73-80.
-
(2003)
Mol Cell Biochem
, vol.243
, pp. 73-80
-
-
Hollenbach, S.1
Thampi, P.2
Viswanathan, T.3
Abraham, E.C.4
-
83
-
-
46749107997
-
Reversal of chaperone activity loss of glycated alphaA-crystallin by a crosslink breaker
-
Datta P, Kallur L, Abraham EC. Reversal of chaperone activity loss of glycated alphaA-crystallin by a crosslink breaker. Mol Cell Biochem 2008;315:137-142.
-
(2008)
Mol Cell Biochem
, vol.315
, pp. 137-142
-
-
Datta, P.1
Kallur, L.2
Abraham, E.C.3
-
84
-
-
84858992894
-
Natural history of age-related retinal lesions that precede AMD in mice fed high or low glycemic index diets
-
Weikel KA, Fitzgerald P, Shang F, Caceres MA, Bian Q, Handa JT, Stitt AW, Taylor A. Natural history of age-related retinal lesions that precede AMD in mice fed high or low glycemic index diets. Invest Ophthalmol Vis Sci 2012; 53:622-632.
-
(2012)
Invest Ophthalmol Vis Sci
, vol.53
, pp. 622-632
-
-
Weikel, K.A.1
Fitzgerald, P.2
Shang, F.3
Caceres, M.A.4
Bian, Q.5
Handa, J.T.6
Stitt, A.W.7
Taylor, A.8
-
85
-
-
17044428933
-
Met72Thr polymorphism of pigment epithelium-derived factor gene and susceptibility to age-related macular degeneration
-
Yamagishi S, Nakamura K, Inoue H, Takeuchi M. Met72Thr polymorphism of pigment epithelium-derived factor gene and susceptibility to age-related macular degeneration. Med Hypotheses 2005;64:1202-1204.
-
(2005)
Med Hypotheses
, vol.64
, pp. 1202-1204
-
-
Yamagishi, S.1
Nakamura, K.2
Inoue, H.3
Takeuchi, M.4
-
86
-
-
58249083292
-
Advanced glycation end product (AGE) accumulation on Bruch's membrane: Links to age-related RPE dysfunction
-
Glenn JV, Mahaffy H, Wu K, Smith G, Nagai R, Simpson DA, Boulton ME, Stitt AW. Advanced glycation end product (AGE) accumulation on Bruch's membrane: Links to age-related RPE dysfunction. Invest Ophthalmol Vis Sci 2009;50:441-451.
-
(2009)
Invest Ophthalmol Vis Sci
, vol.50
, pp. 441-451
-
-
Glenn, J.V.1
Mahaffy, H.2
Wu, K.3
Smith, G.4
Nagai, R.5
Simpson, D.A.6
Boulton, M.E.7
Stitt, A.W.8
-
87
-
-
80052475992
-
Advanced glycation endproduct changes to Bruch's membrane promotes lipoprotein retention by lipoprotein lipase
-
Cano M, Fijalkowski N, Kondo N, Dike S, Handa J. Advanced glycation endproduct changes to Bruch's membrane promotes lipoprotein retention by lipoprotein lipase. Am J Pathol 2011;179:850-859.
-
(2011)
Am J Pathol
, vol.179
, pp. 850-859
-
-
Cano, M.1
Fijalkowski, N.2
Kondo, N.3
Dike, S.4
Handa, J.5
-
88
-
-
77953284618
-
Aldose reductase inhibition ameliorates the detrimental effect of estrogen replacement therapy on neuropathology in diabetic rats subjected to transient forebrain ischemia
-
Shen B, Vetri F, Mao L, Xu HL, Paisansathan C, Pelligrino DA. Aldose reductase inhibition ameliorates the detrimental effect of estrogen replacement therapy on neuropathology in diabetic rats subjected to transient forebrain ischemia. Brain Res 2010;1342:118-126.
-
(2010)
Brain Res
, vol.1342
, pp. 118-126
-
-
Shen, B.1
Vetri, F.2
Mao, L.3
Xu, H.L.4
Paisansathan, C.5
Pelligrino, D.A.6
-
89
-
-
38849150982
-
Inhibitors of advanced glycation end-products prevent loss of enteric neuronal nitric oxide synthase in diabetic rats
-
Jeyabal PV, Kumar R, Gangula PR, Micci MA, Pasricha PJ. Inhibitors of advanced glycation end-products prevent loss of enteric neuronal nitric oxide synthase in diabetic rats. Neurogastroenterol Motil 2008;20:253-261.
-
(2008)
Neurogastroenterol Motil
, vol.20
, pp. 253-261
-
-
Jeyabal, P.V.1
Kumar, R.2
Gangula, P.R.3
Micci, M.A.4
Pasricha, P.J.5
-
90
-
-
61849114069
-
A critical appraisal of erectile function in animal models of diabetes mellitus
-
Gur S, Kadowitz PJ, Hellstrom WJ. A critical appraisal of erectile function in animal models of diabetes mellitus. Int J Androl 2009;32:93-114.
-
(2009)
Int J Androl
, vol.32
, pp. 93-114
-
-
Gur, S.1
Kadowitz, P.J.2
Hellstrom, W.J.3
-
91
-
-
43749101797
-
Erectile dysfunction as a predictor of cardiovascular events and death in diabetic patients with angiographically proven asymptomatic coronary artery disease: A potential protective role for statins and 5-phosphodiesterase inhibitors
-
Gazzaruso C, Solerte SB, Pujia A, Coppola A, Vezzoli M, Salvucci F, Valenti C, Giustina A, Garzaniti A. Erectile dysfunction as a predictor of cardiovascular events and death in diabetic patients with angiographically proven asymptomatic coronary artery disease: A potential protective role for statins and 5-phosphodiesterase inhibitors. J Am Coll Cardiol 2008;51:2040-2044.
-
(2008)
J Am Coll Cardiol
, vol.51
, pp. 2040-2044
-
-
Gazzaruso, C.1
Solerte, S.B.2
Pujia, A.3
Coppola, A.4
Vezzoli, M.5
Salvucci, F.6
Valenti, C.7
Giustina, A.8
Garzaniti, A.9
-
92
-
-
33645968445
-
The breakdown of preformed advanced glycation end products reverses erectile dysfunction in streptozotocin-induced diabetic rats: Preventive versus curative treatment
-
Usta MF, Kendirci M, Gur S, Foxwell NA, Bivalacqua TJ, Cellek S, Hellstrom WJ. The breakdown of preformed advanced glycation end products reverses erectile dysfunction in streptozotocin-induced diabetic rats: Preventive versus curative treatment. J Sex Med 2006;3:242-250.
-
(2006)
J Sex Med
, vol.3
, pp. 242-250
-
-
Usta, M.F.1
Kendirci, M.2
Gur, S.3
Foxwell, N.A.4
Bivalacqua, T.J.5
Cellek, S.6
Hellstrom, W.J.7
-
93
-
-
84861235669
-
Therapeutic effect of combination of alagebrium (ALT-711) and sildenafil on erectile function in diabetic rats
-
doi: 10.1038/ijir.2011.54
-
Gurbuz N, Sagdic G, Sanli A, Ciftcioglu A, Bassorgun I, Baykal A, Usta MF. Therapeutic effect of combination of alagebrium (ALT-711) and sildenafil on erectile function in diabetic rats. Int J Impot Res 2011;doi: 10.1038/ijir.2011.54.
-
Int J Impot Res 2011
-
-
Gurbuz, N.1
Sagdic, G.2
Sanli, A.3
Ciftcioglu, A.4
Bassorgun, I.5
Baykal, A.6
Usta, M.F.7
-
94
-
-
79953009599
-
Limited joint mobility in diabetes and ageing: Recent advances in pathogenesis and therapy
-
Abate M, Schiavone C, Pelotti P, Salini V. Limited joint mobility in diabetes and ageing: Recent advances in pathogenesis and therapy. Int J Immunopathol Pharmacol 2010;23:997-1003.
-
(2010)
Int J Immunopathol Pharmacol
, vol.23
, pp. 997-1003
-
-
Abate, M.1
Schiavone, C.2
Pelotti, P.3
Salini, V.4
-
95
-
-
79960103186
-
Limited joint mobility (LJM) in elderly subjects with type II diabetes mellitus
-
Abate M, Schiavone C, Pelotti P, Salini V. Limited joint mobility (LJM) in elderly subjects with type II diabetes mellitus. Arch Gerontol Geriatr 2011;53:135-140.
-
(2011)
Arch Gerontol Geriatr
, vol.53
, pp. 135-140
-
-
Abate, M.1
Schiavone, C.2
Pelotti, P.3
Salini, V.4
-
97
-
-
8144223671
-
RAGE potentiates Abeta-induced perturbation of neuronal function in transgenic mice
-
Arancio O, Zhang HP, Chen X, Lin C, Trinchese F, Puzzo D, Liu S, Hegde A, Yan SF, Stern A, Luddy JS, Lue LF, Walker DG, Roher A, Buttini M, Mucke L, Li W, Schmidt AM, Kindy M, Hyslop PA, Stern DM, Yan SS. RAGE potentiates Abeta-induced perturbation of neuronal function in transgenic mice. EMBO J 2004;23:4096-4105.
-
(2004)
EMBO J
, vol.23
, pp. 4096-4105
-
-
Arancio, O.1
Zhang, H.P.2
Chen, X.3
Lin, C.4
Trinchese, F.5
Puzzo, D.6
Liu, S.7
Hegde, A.8
Yan, S.F.9
Stern, A.10
Luddy, J.S.11
Lue, L.F.12
Walker, D.G.13
Roher, A.14
Buttini, M.15
Mucke, L.16
Li, W.17
Schmidt, A.M.18
Kindy, M.19
Hyslop, P.A.20
Stern, D.M.21
Yan, S.S.22
more..
-
98
-
-
84859723641
-
A multimodal RAGE-specific inhibitor reduces amyloid bmediated brain disorder in a mouse model of Alzheimer disease
-
Deane R, Singh I, Sagare AP, Bell RD, Ross NT, Larue B, Love R, Perry S, Paquette N, Deane RJ, Thiyagarajan M, Zarcone T, Fritz G, Friedman AE, Miller BL, Zlokovic BV. A multimodal RAGE-specific inhibitor reduces amyloid bmediated brain disorder in a mouse model of Alzheimer disease. J Clin Invest 2012;122:1377-1392.
-
(2012)
J Clin Invest
, vol.122
, pp. 1377-1392
-
-
Deane, R.1
Singh, I.2
Sagare, A.P.3
Bell, R.D.4
Ross, N.T.5
Larue, B.6
Love, R.7
Perry, S.8
Paquette, N.9
Deane, R.J.10
Thiyagarajan, M.11
Zarcone, T.12
Fritz, G.13
Friedman, A.E.14
Miller, B.L.15
Zlokovic, B.V.16
-
99
-
-
0034535011
-
Neurotoxicity of advanced glycation end-products for cultured cortical neurons
-
Takeuchi M, Bucala R, Suzuki T, Ohkubo T, Yamazaki M, Koike T, Kameda Y, Makita Z. Neurotoxicity of advanced glycation end-products for cultured cortical neurons. J Neuropathol Exp Neurol 2000;59:1094-1105.
-
(2000)
J Neuropathol Exp Neurol
, vol.59
, pp. 1094-1105
-
-
Takeuchi, M.1
Bucala, R.2
Suzuki, T.3
Ohkubo, T.4
Yamazaki, M.5
Koike, T.6
Kameda, Y.7
Makita, Z.8
-
100
-
-
82255179765
-
Advanced glycation end product level, diabetes, and accelerated cognitive aging
-
Yaffe K, Lindquist K, Schwartz AV, Vitartas C, Vittinghoff E, Satterfield S, Simonsick EM, Launer L, Rosano C, Cauley JA, Harris T. Advanced glycation end product level, diabetes, and accelerated cognitive aging. Neurology 2011; 77:1351-1356.
-
(2011)
Neurology
, vol.77
, pp. 1351-1356
-
-
Yaffe, K.1
Lindquist, K.2
Schwartz, A.V.3
Vitartas, C.4
Vittinghoff, E.5
Satterfield, S.6
Simonsick, E.M.7
Launer, L.8
Rosano, C.9
Cauley, J.A.10
Harris, T.11
-
101
-
-
68249149199
-
TRC4186, a novel AGEbreaker, improves diabetic cardiomyopathy and nephropathy in Ob-ZSF1 model of type 2 diabetes
-
Joshi D, Gupta R, Dubey A, Shiwalkar A, Pathak P, Gupta RC, Chauthaiwale V, Dutt C. TRC4186, a novel AGEbreaker, improves diabetic cardiomyopathy and nephropathy in Ob-ZSF1 model of type 2 diabetes. J Cardiovasc Pharmacol 2009;54:72-81.
-
(2009)
J Cardiovasc Pharmacol
, vol.54
, pp. 72-81
-
-
Joshi, D.1
Gupta, R.2
Dubey, A.3
Shiwalkar, A.4
Pathak, P.5
Gupta, R.C.6
Chauthaiwale, V.7
Dutt, C.8
-
102
-
-
68949098291
-
Phase i clinical studies of the advanced glycation end-product (AGE)-breaker TRC4186: Safety, tolerability and pharmacokinetics in healthy subjects
-
Chandra KP, Shiwalkar A, Kotecha J, Thakkar P, Srivastava A, Chauthaiwale V, Sharma SK, Cross MR, Dutt C. Phase I clinical studies of the advanced glycation end-product (AGE)-breaker TRC4186: Safety, tolerability and pharmacokinetics in healthy subjects. Clin Drug Investig 2009; 29:559-575.
-
(2009)
Clin Drug Investig
, vol.29
, pp. 559-575
-
-
Chandra, K.P.1
Shiwalkar, A.2
Kotecha, J.3
Thakkar, P.4
Srivastava, A.5
Chauthaiwale, V.6
Sharma, S.K.7
Cross, M.R.8
Dutt, C.9
-
103
-
-
51349096936
-
TRC4149 a novel advanced glycation end product breaker improves hemodynamic status in diabetic spontaneously hypertensive rats
-
Pathak P, Gupta R, Chaudhari A, Shiwalkar A, Dubey A, Mandhare AB, Gupta RC, Joshi D, Chauthaiwale V. TRC4149 a novel advanced glycation end product breaker improves hemodynamic status in diabetic spontaneously hypertensive rats. Eur J Med Res 2008;13:388-398.
-
(2008)
Eur J Med Res
, vol.13
, pp. 388-398
-
-
Pathak, P.1
Gupta, R.2
Chaudhari, A.3
Shiwalkar, A.4
Dubey, A.5
Mandhare, A.B.6
Gupta, R.C.7
Joshi, D.8
Chauthaiwale, V.9
-
104
-
-
80051959176
-
The advanced glycation end product-lowering agent ALT-711 is a low-affinity inhibitor of thiamine diphosphokinase
-
Krautwald M, Leech D, Horne S, Steele ML, Forbes J, Rahmadi A, Griffith R, Munch G. The advanced glycation end product-lowering agent ALT-711 is a low-affinity inhibitor of thiamine diphosphokinase. Rejuvenation Res 2011;14:383-391.
-
(2011)
Rejuvenation Res
, vol.14
, pp. 383-391
-
-
Krautwald, M.1
Leech, D.2
Horne, S.3
Steele, M.L.4
Forbes, J.5
Rahmadi, A.6
Griffith, R.7
Munch, G.8
-
105
-
-
0032944619
-
Rapid hydrolysis and slow alpha, beta-dicarbonyl cleavage of an agent proposed to cleave glucose-derived protein cross-links
-
Thornalley PJ, Minhas HS. Rapid hydrolysis and slow alpha, beta-dicarbonyl cleavage of an agent proposed to cleave glucose-derived protein cross-links. Biochem Pharmacol 1999;57:303-307.
-
(1999)
Biochem Pharmacol
, vol.57
, pp. 303-307
-
-
Thornalley, P.J.1
Minhas, H.S.2
-
106
-
-
0037376556
-
AGE-breakers cleave model compounds, but do not break Maillard crosslinks in skin and tail collagen from diabetic rats
-
Yang S, Litchfield JE, Baynes JW. AGE-breakers cleave model compounds, but do not break Maillard crosslinks in skin and tail collagen from diabetic rats. Arch Biochem Biophys 2003;412:42-46.
-
(2003)
Arch Biochem Biophys
, vol.412
, pp. 42-46
-
-
Yang, S.1
Litchfield, J.E.2
Baynes, J.W.3
-
107
-
-
84857430527
-
Chelation: A fundamental mechanism of action of AGE inhibitors, AGE breakers, and other inhibitors of diabetes complications
-
Nagai R, Murray DB, Metz TO, Baynes JW. Chelation: A fundamental mechanism of action of AGE inhibitors, AGE breakers, and other inhibitors of diabetes complications. Diabetes 2012;61:549-559.
-
(2012)
Diabetes
, vol.61
, pp. 549-559
-
-
Nagai, R.1
Murray, D.B.2
Metz, T.O.3
Baynes, J.W.4
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