Cleavage of in vitro and in vivo formed lens protein cross-links by a novel cross-link breaker

Molecular and Cellular Biochemistry

Volumn 243, Issue 1-2, 2003, Pages 73-80

  Hollenbach, Seth ^a   Thampi, Prajitha ^a   Viswanathan, Tito ^b   Abraham, Edathara C ^a  

^a UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES   (United States)

^b University of Arkansas   (United States)

Author keywords

Cross link breakers; Diabetes; Eye lens; Glycation; Protein cross linking; Thiazolium compounds

Indexed keywords

ACETYLSALICYLIC ACID; ADVANCED GLYCATION END PRODUCT; ALAGEBRIUM; ALPHA CRYSTALLIN; AMINOGUANIDINE; GLUCOSE 6 PHOSPHATE; LENS PROTEIN; N PHENACYL 4,5 DIMETHYLTHIAZOLIUM BROMIDE; STREPTOZOCIN; THIAZOLE DERIVATIVE; UNCLASSIFIED DRUG;

ADULT; ARTICLE; CASE REPORT; CHEMICAL BOND; CHEMICAL STRUCTURE; CONTROLLED STUDY; DIABETES MELLITUS; DIABETIC RETINOPATHY; DRUG MECHANISM; DRUG STRUCTURE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; IN VITRO STUDY; IN VIVO STUDY; MOLECULAR WEIGHT; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; POLYACRYLAMIDE GEL ELECTROPHORESIS; PROTEIN CROSS LINKING; PROTEIN DEGRADATION; PROTEIN GLYCOSYLATION;

ALPHA-CRYSTALLIN A CHAIN; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DENSITOMETRY; DIABETES MELLITUS; ELECTROPHORESIS, POLYACRYLAMIDE GEL; GLUCOSE-6-PHOSPHATE; GLYCOSYLATION END PRODUCTS, ADVANCED; HUMANS; LENS, CRYSTALLINE; MIDDLE AGED; MODELS, CHEMICAL; RECOMBINANT PROTEINS; THIAZOLES; TIME FACTORS;

EID: 0037281152     PISSN: 03008177     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1021660105893     Document Type: Article

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